Pesticidal compounds

ABSTRACT

The present invention relates to the compounds of formula (I), and the N-oxides, stereoisomers, tautomers and agriculturally or veterinarily acceptable salts thereof wherein the variables are defined according to description formula (I). The compounds of formula (I), as well as the N-oxides, stereoisomers, tautomers and agriculturally or veterinarily acceptable salts thereof, are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.

Invertebrate pests and in particular insects, arachnids and nematodes destroy growing and harvested crops and attack wooden dwelling and commercial structures, thereby causing large economic loss to the food supply and to property. Accordingly, there is an ongoing need for new agents for combating invertebrate pests.

Carbamoylated and thiocarbamoylated oxime derivatives are known for pesticidal use, for example, in patent publications WO 2016/156076, semi-carbazones and thiosemicarbazones derivatives are known for pesticidal use in patent publication WO 2016/116445.

Due to the ability of target pests to develop resistance to pesticidally-active agents, there is an ongoing need to identify further compounds, which are suitable for combating invertebrate pests such as insects, arachnids and nematodes. Furthermore, there is a need for new compounds having a high pesticidal activity and showing a broad activity spectrum against a large number of different invertebrate pests, especially against difficult to control insects, arachnids and nematodes.

It is therefore an object of the present invention to identify and provide compounds, which exhibit a high pesticidal activity and have a broad activity spectrum against invertebrate pests.

It has been found that these objects can be achieved by substituted bicyclic compounds of formula I, as depicted and defined below, including their stereoisomers, their salts, in particular their agriculturally or veterinarily acceptable salts, their tautomers and their N-oxides.

In a first aspect, the present invention relates to the compounds of formula I,

-   -   wherein     -   A¹ is N or CR^(A1);     -   A² is N or CR^(A2);     -   A³ is N or CR^(A3);     -   wherein at least one of the A¹, A², A³ is N;     -   B¹ is N or CR^(B1); preferably B¹ is CR^(B1);     -   B² is N or CR^(B2); preferably B² is CR^(B2);     -   B³ is N or CR^(B3); preferably B³ is CR^(B3);     -   R^(A1), R^(A2), and R^(A3) independently of each other are         selected from H, halogen, N₃, OH, CN, NO₂, —SCN, —SF₅,         C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, tri-C₁-C₆-alkylsilyl,         C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl,         C₁-C₆-alkoxy-C₁-C₄-alkoxy, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkoxy,         C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₁-C₄-alkyl-C₃-C₆-cycloalkoxy,         wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and         cycloalkoxy moieties are unsubstituted or substituted with         halogen,     -    C(═O)—OR^(a), NR^(b)R^(c), C₁-C₆-alkylene-NR^(b)R^(c),         O—C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN,         NH—C₁-C₆-alkylene-NR^(b)R^(c), C(═O)—NR^(b)R^(c), C(═O)—R^(d),         SO₂NR^(b)R^(c), or S(═O)_(m)R^(e), phenyl, phenoxy,         phenylcarbonyl, phenylthio, or —CH₂-phenyl, wherein the phenyl         rings are unsubstituted or substituted with R^(f);     -   R^(B1), R^(B2), and R^(B3), independently of each other are H,         halogen, N3, OH, CN, NO₂, —SCN, —SF₅, C₁-C₆-alkyl, C₁-C₆-alkoxy,         C₂-C₆-alkenyl, tri-C₁-C₆-alkylsilyl, C₂-C₆-alkynyl,         C₁-C₆-alkoxy-C₁-C₄-alkyl, C₁-C₆-alkoxy-C₁-C₄-alkoxy,         C₃-C₆-cycloalkyl, C₃-C₆-cycloalkoxy,         C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₁-C₄-alkyl-C₃-C₆-cycloalkoxy,         wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and         cycloalkoxy moieties are unsubstituted or substituted with         halogen,     -    C(═O)—OR^(a), NR^(b)R^(c), C₁-C₆-alkylene-NR^(b)R^(c),         O—C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN,         NH—C₁-C₆-alkylene-NR^(b)R^(c), C(═O)—NR^(b)R^(c), C(═O)—R^(d),         SO₂NR^(b)R^(c), or S(═O)_(m)R^(e), phenyl, phenoxy,         phenylcarbonyl, phenylthio, or —CH₂-phenyl, wherein the phenyl         rings are unsubstituted or substituted with R^(f);     -   Q is —N═C(X)—, —N(R²)—C(═NR)—, or —N(R²)—C(═S)—, —C(R⁴R⁵)—O—,         —C(═O)—O—, —S(═O)_(m)—C(R⁷R⁸)—, —N(R²)—S(═O)_(m)—,         —N(R²)—C(R⁹R¹⁰)—, —C(═O)—C(R¹⁹R²⁰)—, —N(R²)—C(═O)—,         —C(R¹³R¹⁴)—C(R¹⁵R¹⁶)—, or —C(R¹⁷)═C(R¹⁸)—; wherein Ar is bound         to either side of Q;     -   X is identical or different, H, halogen, SR⁷, OR⁸, N(R³)₂,         —CR⁴═N(OCH₃), CN, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl,         C₃-C₆-cycloalkyl, wherein the alkyl, alkenyl, alkynyl and         cycloalkyl moieties are unsubstituted or substituted with         halogen; phenyl, or —CH₂-phenyl, wherein the phenyl rings are         unsubstituted or substituted with R^(f);     -   R is identical or different, H, CN, C₁-C₆-alkyl, C₂-C₆-alkenyl,         C₂-C₆-alkynyl, C₃-C₆-cycloalkyl, wherein the alkyl, alkenyl,         alkynyl and cycloalkyl moieties are unsubstituted or substituted         with halogen,     -    SR⁷, OR⁸, N(R³)₂, phenyl, or —CH₂-phenyl, wherein the phenyl         rings are unsubstituted or substituted with R^(f);     -   R² is H, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl,         C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl,         C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl,         wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and         cycloalkoxy moieties are unsubstituted or substituted with         halogen,     -    C(O)—OR^(a), C₁-C₆-alkylen-NR^(b)R^(c), C₁-C₆-alkylen-CN,         C(O)—NR^(b)R^(c), C(O)—R^(d), SO₂NR^(b)R^(c), S(═O)_(m)R^(e),         phenyl, or —CH₂-phenyl, wherein the phenyl rings are         unsubstituted or substituted with R^(f);     -   R³ is H, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl,         C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl,         C₃-C₆-cycloalkyl-C₁-C₄-alkyl, or C₃-C₆-cycloalkoxy-C₁-C₄-alkyl,         wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and         cycloalkoxy moieties are unsubstituted or substituted with         halogen,     -    C₁-C₆-alkylene-CN, phenyl, or —CH₂-phenyl, wherein the phenyl         rings are unsubstituted or substituted with R^(f);     -   R⁴, R⁵, R⁷, R⁸, R⁹, R¹⁰, R¹³, R¹⁴, R¹⁵, R¹⁶, R¹⁷, R¹⁸, R¹⁹, R²⁰         are, identical or different, H, halogen, C₁-C₆-alkyl,         C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl,         C₃-C₆-cycloalkyl, C₃-C₆-cycloalkyl-C₁-C₄-alkyl,         C₃-C₆-cycloalkoxy-C₁-C₄-alkyl, wherein the alkyl, alkoxy,         alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are         unsubstituted or substituted with halogen,     -    C(═O)—OR^(a), C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN,         C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), S(═O)_(m)R^(e),         phenyl, or —CH₂-phenyl, wherein the phenyl rings are         unsubstituted or substituted with R^(f);     -   R⁶ is H, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl,         C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl,         C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl,         wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and         cycloalkoxy moieties are unsubstituted or substituted with         halogen,     -    C(═O)—OR^(a), C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN,         C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), S(═O)_(m)R^(e),         phenyl, —CH₂—C(═O)—OR^(a), or —CH₂-phenyl, wherein the phenyl         rings are unsubstituted or substituted with R^(f);     -   Ar is phenyl or 5- or 6-membered hetaryl, which are         unsubstituted or substituted with R^(Ar), wherein     -   R^(Ar) is halogen, N₃, OH, CN, NO₂, —SCN, —SF₅, C₁-C₆-alkyl,         C₁-C₆-alkoxy, C₂-C₆-alkenyl, tri-C₁-C₆-alkylsilyl,         C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl,         C₁-C₆-alkoxy-C₁-C₄-alkoxy, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkoxy,         C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl,         wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and         cycloalkoxy moieties are unsubstituted or substituted with         halogen,     -    C(═O)—OR^(a), NR^(b)R^(c), C₁-C₆-alkylene-NR^(b)R^(c),         O—C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN,         NH—C₁-C₆-alkylene-NR^(b)R^(c), C(═O)—NR^(b)R^(c), C(═O)—R^(d),         SO₂NR^(b)R^(c), or S(═O)_(m)R^(e), phenyl, phenoxy,         phenylcarbonyl, phenylthio or —CH₂-phenyl, wherein phenyl rings         are unsubstituted or substituted with R^(f);     -   R¹ is a moiety of formula Y—Z-T-R¹¹ or Y—Z-T-R¹²; wherein         -   Y is —CR^(ya)═N—, wherein the N is bound to Z;         -   —NR^(yc)—C(═O)—, wherein C(═O) is bound to Z; or         -   —NR^(yc)—C(═S)_wherein C(═S) is bound to Z;         -   Z is a single bond;         -   —NR^(zc)—C(═O)—, wherein C(═O) is bound to T;         -   —NR^(zc)—C(═S)—, wherein C(═S) is bound to T;         -   —N═C(S—R^(za))—, wherein T is bound to the carbon atom;         -   O—C(═O)—, wherein T is bound to the carbon atom; or         -   —NR^(zc)—C(S—R^(za))═, wherein T is bound to the carbon             atom;         -   T is O, N or N—R^(T);         -   R¹¹ is C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl,             C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl,             C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₁-C₄-alkyl-C₃-C₆-cycloalkoxy,             wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and             cycloalkoxy moieties are unsubstituted or substituted with             halogen,     -    C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN,         C(═O)—NR^(b)R^(c), C(═O)—R^(d), aryl, aryl-carbonyl,         aryl-C₁-C₄-alkyl, aryloxy-C₁-C₄-alkyl, heteroaryl,         carbonyl-heteroaryl, heteroaryl-C₁-C₄-alkyl or         heteroaryloxy-C₁-C₄-alkyl, wherein the phenyl rings are         unsubstituted or substituted with R^(g) and wherein the         heteroaryl is a 5- or 6-membered monocyclic heteroaryl or a 8-,         9- or 10-membered bicyclic heteroaryl;         -   R¹² is a radical of the formula A¹;

-   -   wherein # indicates the point of attachment to T;         -   R¹²¹, R¹²², R¹²³ are, identical or different, H, halogen,             C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl,             C₁-C₆-alkoxy-C₁-C₄-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyloxy,             C₂-C₆-alkynyloxy, C₁-C₆-alkoxy-C₁-C₄-alkoxy,             C₁-C₆-alkylcarbonlyoxy, C₁-C₆-alkenylcarbonlyoxy,             C₃-C₆-cycloalkylcarbonlyoxy, wherein the alkyl, alkoxy,             alkenyl, alkenyloxy, alkynyl, alkynyloxy and cycloalkyl             moieties are unsubstituted or substituted with halogen, or             NR^(b)R^(c), or one of R¹²¹, R¹²², R¹²³ may also be oxo;         -   R¹²⁴ is H, C₁-C₆-alkyl, C₁-C₆-alkoxy-C₁-C₄-alkyl,             C₁-C₆-alkoxy, or C₂-C₆-alkenyloxy, wherein the alkyl,             alkoxy, alkenyl and alkenyloxy moieties are unsubstituted or             substituted with halogen;         -   and where     -   R^(ya) is H, halogen, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl,         C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl,         C₁-C₄-alkyl-C₃-C₆-cycloalkyl, C₁-C₄-alkyl-C₃-C₆-cycloalkoxy,         wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and         cycloalkoxy moieties are unsubstituted or substituted with         halogen,     -    C(═O)—OR^(a), C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN,         C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), S(═O)_(m)R^(e),         phenyl, or —CH₂-phenyl, wherein the phenyl rings are         unsubstituted or substituted with R^(f);     -   R^(yc), R^(zc) are, identical or different, H, C₁-C₆-alkyl,         C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₄-alkyl-C₁-C₆-alkoxy,         C₃-C₆-cycloalkyl, C₁-C₄-alkyl-C₃-C₆-cycloalkyl, or         C₁-C₄-alkyl-C₃-C₆-cycloalkoxy, wherein the alkyl, alkoxy,         alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are         unsubstituted or substituted with halogen;     -   R^(T) is H, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl,         C₁-C₄-alkyl-C₁-C₆-alkoxy, C₃-C₆-cycloalkyl,         C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl,         wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and         cycloalkoxy moieties are unsubstituted or substituted with         halogen,     -    C(═O)—OR^(a), C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN,         C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), S(═O)_(m)R^(e),         phenyl, or —CH₂-phenyl, wherein the phenyl rings are         unsubstituted or substituted with R^(f);     -   R^(zc) together with R^(T) if present, may form C₁-C₆-alkylene         or a linear C₂-C₆-alkenylene group, where in the linear         C₁-C₆-alkylene and the linear C₂-C₆-alkenylene a CH₂ moiety may         be replaced by a carbonyl or a C═N—R′ and/or wherein 1 or 2 CH₂         moieties may be replaced by O or S and/or wherein the linear         C₁-C₆-alkylene and the linear C₂-C₆-alkenylene may be         unsubstituted or substituted with R^(h);     -   R^(za) is H, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl,         tri-C₁-C₆-alkylsilyl, C₂-C₆-alkynyl, C₁-C₄-alkyl-C₁-C₆-alkoxy,         C₃-C₆-cycloalkyl, C₁-C₄-alkyl-C₃-C₆-cycloalkoxy,         C₁-C₄-alkyl-C₃-C₆-cycloalkyl, wherein the alkyl, alkoxy,         alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are         unsubstituted or substituted with halogen,     -    C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN,         C(═O)—NR^(b)R^(c), C(═O)—R^(d), phenyl, phenylcarbonyl, or         —CH₂-phenyl, wherein the phenyl rings are unsubstituted or         substituted with R^(f);     -   R^(za) together with R^(T) if present, may form C₁-C₆-alkylene         or a linear C₂-C₆-alkenylene group, where in the linear         C₁-C₆-alkylene and the linear C₂-C₆-alkenylene a CH₂ moiety may         be replaced by a carbonyl or a C═N—R′ and/or wherein 1 or 2 CH₂         moieties may be replaced by O or S and/or wherein the linear         C₁-C₆-alkylene and the linear C₂-C₆-alkenylene may be         unsubstituted or substituted with R^(h);     -   R^(a), R^(b) and R^(c) are, identical or different, H,         C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, C₂-C₆-alkynyl,         C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl,         C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl,         wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and         cycloalkoxy moieties are unsubstituted or substituted with         halogen,     -    C₁-C₆-alkylene-CN, phenyl, or —CH₂-phenyl, wherein the phenyl         rings are unsubstituted or substituted with R^(f);     -   R^(b) and R^(c) together with the nitrogen they are attached may         form 5- or 6-membered saturated, partially or fully unsaturated         heterocyclic ring;     -   R^(d) is H, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl,         C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl,         C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl,         wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and         cycloalkoxy moieties are unsubstituted or substituted with         halogen,     -    phenyl, or —CH₂-phenyl, wherein the phenyl rings are         unsubstituted or substituted with R^(f);     -   R^(e) is C₁-C₆-alkyl, C₃-C₆-cycloalkyl,         C₃-C₆-cycloalkyl-C₁-C₄-alkyl, wherein the alkyl, cycloalkyl         moieties are unsubstituted or substituted with halogen,     -    phenyl and —CH₂-phenyl, wherein the phenyl rings are         unsubstituted or substituted with R^(f);     -   R^(f) is halogen, N3, OH, CN, NO₂, —SCN, —SF₅, C₁-C₆-alkyl,         C₁-C₆-alkoxy, C₂-C₆-alkenyl, tri-C₁-C₆-alkylsilyl,         C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl,         C₃-C₆-alkoxy-C₁-C₄-alkoxy, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkoxy,         C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxyx-C₁-C₄-alkyl,         wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and         cycloalkoxy moieties are unsubstituted or substituted with         halogen,     -    C(═O)—OR^(a), NR^(b)R^(c), C₁-C₆-alkylene-NR^(b)R^(c),         O—C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN,         NH—C₁-C₆-alkylene-NR^(b)R^(c), C(═O)—NR^(b)R^(c), C(═O)—R^(d),         SO₂NR^(b)R^(c), or S(═O)_(m)R^(e);     -   R^(g) is halogen, N₃, OH, CN, NO₂, —SCN, —SF₅, C₁-C₆-alkyl,         C₁-C₆-alkoxy, C₂-C₆-alkenyl, tri-C₁-C₆-alkylsilyl,         C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl,         C₁-C₆-alkoxy-C₁-C₄-alkoxy, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkoxy,         C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl,         wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and         cycloalkoxy moieties are unsubstituted or substituted with         halogen,     -    C(═O)—OR^(a), NR^(b)R^(c), C₁-C₆-alkylene-NR^(b)R^(c),         O—C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN,         NH—C₁-C₆-alkylene-NR^(b)R^(c), C(═O)—NR^(b)R^(c), C(═O)—R^(d),         SO₂NR^(b)R^(c), or S(═O)_(m)R^(e);     -   R^(h) is halogen, OH, C₁-C₆-alkyl, C₃-C₆-cycloalkyl, or CN;     -   m is 0, 1, or 2;         and the N-oxides, stereoisomers, tautomers and agriculturally or         veterinarily acceptable salts thereof.

Moreover, the present invention also relates to processes and intermediates for preparing compounds of formula I and to active compound combinations comprising them. Moreover, the present invention relates to agricultural or veterinary compositions comprising the compounds of formula I, and to the use of the compounds of formula I or compositions comprising them for combating or controlling invertebrate pests and/or for protecting crops, plants, plant propagation material and/or growing plants from attack and/or infestation by invertebrate pests. The present invention also relates to methods of applying the compounds of formula I. Furthermore, the present invention relates to seed comprising compounds of formula I. Wherein the compounds of formula I includes N-oxides, stereoisomers, tautomers and agriculturally or veterinarily acceptable salts thereof.

With due modification of the starting compounds, the compounds of formula I can be prepared by procedures as given in below schemes.

Compounds of the formula S1-2 can be prepared in amide coupling reactions between an amine (ArNHR²) and compounds of the formula S1-1 using a coupling reagent such as HATU as described by, for example, Tobinaga, et al WO 2018/021447 (Scheme 1). Alternatively compounds of the formula S1-1 can be pre-activated as an acid chloride by reaction with, for example, SOCl₂, prior to reaction with an amine (ArNHR²) in the presense of a base (e.g. Et₃N) to form compounds of the formula S1-2. Compounds of the formula S1-3 can, in turn, be prepared by reaction of compounds of the formula S1-2 with a thionating reagent such at P₂S₅ as described by, for example, Carroll et al, WO 2008/130953. Compounds of the formula S1-4 can be synthesized by reaction of compounds of the formula S1-2 with a reducing agent such as BH₃.SMe₂ as described by, for example, Chen et al, WO 2009/135299.

Compounds of the formula S2-2 can be prepared from compounds of the formula S2-1 by reaction with, for example, hydroxylamine hydrochloride in the presence of a base (e.g. NaOH, pyridine, triethylamine, K₂CO₃, NaH) as described by, for example, Sanders et al, J. Am. Chem. Soc. 2011, 133, 949-957 (Scheme 2). Compounds of the formula S2-3 can be prepared from compounds of the formula S2-2 by reaction with a chlorinating reagent (e.g. N-chlorosuccinimide, NaOCl, t-butylhypochlorite) as described by, for example, Sanders et al, J. Am. Chem. Soc. 2011, 133, 949-957. Compounds of the formula S2-4 can be prepared from compounds of the formula S2-3 by reaction with an amine nucleophile (ArNHR²) as described by, for example, Altug et al, Tetrahedron Lett. 2009, 50, 7392-7394. Compounds of the formula S2-5 can be prepared from compounds of the formula S2-4 by reaction with an electrophile (e.g. methyl iodide, cyanogen bromide, acetyl chloride etc.) in the presence of a base (e.g. NaOH, pyridine, triethylamine, K₂CO₃, NaH) as described by, for example, Lui et al, Pest. Manag. Sci. 2009, 65, 229-234.

Compounds of the formula S3-2 (R=Me, Et) can be prepared from compounds of the formula S3-1 by reaction with, for example, hydrochloric acid in methanol as described by, for example, Laurent et al, Molecules, 2010, 15, 4283-4293 (Scheme 3). Compounds of the formula S3-3 can be prepared from compounds of the formula S3-2 by reaction with an amine nucleophile (ArNHR²) as described by, for example, Arnold et al, WO 2008/124849.

Compounds of the formula S4-2 can be prepared via compounds of the formula S4-1 by reaction of compounds of the formula S1-2 with a chlorinating agent (e.g. N-chlorosuccinimide, NaOCl, t-butylhypochlorite) followed by a hydrazine [H₂NN(R³)₂] as described by, for example, Crimmin et al, Dalton Trans., 2011, 42, 514-522 (Scheme 4). Compounds of the formula S4-2 can also be prepared from compounds of the formula S1-3 by reaction with, for example, a hydrazine [H₂NN(R³)₂] as described by, for example, Burlison et al, WO 2009/158026.

Compounds of the formula S5-3 can be prepared by reaction of compounds of the formula S5-1 with a reducing agent, for example, LiAlH₄. The resultant compounds of the formula S5-2 can then by reacted with aryl alcohol (ArOH) under Mitsonobu conditions to form compounds of the formula S5-3 (Scheme 5). Compounds for the formula S5-5 can be prepared by reaction of compounds of the formula S5-2 with a chlorinating reagent (e.g. SOCl₂, POCl₃) as described by, for example, Miyahara et al, WO 2017/209155. The resultant compounds of the formula S5-4 can then be converted into compounds of the formula S5-2 by reaction with an arylthiol (ArSH). Compounds of the formula of the formula S5-6 can, in turn, be prepared by reaction of compounds of the formula S5-5 with an oxidizing agent (e.g. MCPBA). Compounds of the formula S1-4 can also be prepared by reducing compounds of the formula of the formula S5-1 with, e.g. DIBAL. The resultant compounds of the formula 52-1 can then be reacted with an amine (ArNHR²) in a reductive amination with, e.g. Na(CN)BH₃ to form compounds of the formula S1-4.

Compounds of the formula S6-4 can be prepared by treating compounds of the formula S6-1 a halogenating agent (e.g. POCl₃, PBr₃) (Scheme 6). The resultant compounds of the formula S6-2 can then be reacted with an amine (R²NH₂) in an S_(N)Ar reaction or palladium-catalyzed amination as described by, for example, Ojida et al, WO 2018/084321 or Hatakeyama et al, WO 2018/110497, respectively. Alternatively The resultant compounds of the formula S6-2 can be acylated with an aryl acid (or chloride) to form compounds of the formula S6-3.

Compounds of the formula S7-1, S7-2, S7-3 and S7-4 are isomers of compounds depicted in Scheme 1-4 and, as such, can be synthesized using analogous procedures are those described above (Scheme 7).

Compounds of the formula S8-1 can be prepared in analogy to compounds of the formula S6-3 (Scheme 8). Compounds of the formula S8-2 can be prepared from compounds of the formula S6-1 by reaction with an alcohol [ArC(R⁹)(R¹⁰)OH] in an S_(N)Ar reaction or copper-catalyzed ether formation reaction as described by, for example, Long et al, WO 2018/059534 or Gao et al WO 2016/150193, respectively. Compounds of the formula S8-3 can be prepared from compounds of the formula S6-1 by reaction with a thiol [ArC(R⁹)(R¹⁰)SH] in an S_(N)Ar reaction or palladium-catalyzed thioether formation reaction as described by, for example, Wang et al, WO 2017/198196 or Barrow et al, WO 2016/123577.

Compounds of the formula S9-3 can be prepared by oxidation of compounds of the formula S9-1 with, e.g. MCPBA as described by, for example, Rinderspacher et al, US 2017/0210759 (Scheme 9). The resultant compounds of the formula S9-2 can be converted into compounds of the formula S9-3 by reaction with an acylating agent (e.g. Ac₂O) followed by a basic hydrolysis (e.g. with NaOH).

Compounds of the formula S10-2 can be prepared by condensation of compounds of the formula S10-1 with, e.g. formamide as described by, for example, Ojida et al, WO 2018/084321 (Scheme 10).

Compounds of the formula S11-2 can be prepared by reaction of compounds of the formula S11-1 with hydrazine as described by, for example, Siu et al, WO 2016/164285 (Scheme 11).

Compounds of the formula S12-2 (R=Me, Et) can be prepared in a palladium-catalyzed carbonylation of compounds of the formula S12-1 using CO (g) and MeOH or EtOH as described by, for example, Evans et al, WO 2017/214269 (Scheme 12). Compounds of the formula S12-4 can, in turn, be prepared from Compounds of the formula S12-2 by, e.g. basic hydrolysis, compounds of the formula S12-3 can also be prepared from compounds of the formula S12-2 by reduction with, e.g. DIBAL.

Compounds of the formula S12-4, S12-3 and S13-1 can be converted in known syntheses into compounds on the formula (I) as described by, for example, Crouse et al, WO 2009/102736, Crouse et al, WO 2010/093764, Crouse et al, US 2012/0202687, Crouse et al, WO 2013/009791, Baum et al, WO 2013/116052, Fischer et al, WO 2013/116053, Crouse et al, WO 2014/011429, Jeanguenat et al, WO 2016/116445 and Narine et al, WO 2018/177781 (Scheme 13).

Individual compounds of formula I can also be prepared by derivatisation of other compounds of formula I or the intermediates thereof.

If the synthesis yields mixtures of isomers, a separation is generally not necessarily required since in some cases the individual isomers can be interconverted during work-up for use or during application (for example under the action of light, acids or bases). Such conversions may also take place after use, for example in the treatment of plants in the treated plant, or in the harmful fungus to be controlled.

A skilled person will readily understand that the preferences for the substituents, also in particular the ones given in the tables below for the respective substituents, given herein in connection with compounds I apply for the intermediates accordingly. Thereby, the substituents in each case have independently of each other or more preferably in combination the meanings as defined herein.

Unless otherwise indicated, the term “compound(s) according to the invention” or “compound(s) of the invention” or “compound(s) of formula (I)”, refers to the compounds of formula I.

The term “compound(s) according to the invention”, or “compounds of formula I” comprises the compound(s) as defined herein as well as a stereoisomer, salt, tautomer or N-oxide thereof. The term “compound(s) of the present invention” is to be understood as equivalent to the term “compound(s) according to the invention”, therefore also comprising a stereoisomer, salt, tautomer or N-oxide thereof.

The term “composition(s) according to the invention” or “composition(s) of the present invention” encompasses composition(s) comprising at least one compound of formula I according to the invention as defined above. The compositions of the invention are preferably agricultural or veterinary compositions.

Depending on the substitution pattern, the compounds according to the invention may have one or more centers of chirality, in which case they are present as mixtures of enantiomers or diastereomers. The invention provides both the single pure enantiomers or pure diastereomers of the compounds according to the invention, and their mixtures and the use according to the invention of the pure enantiomers or pure diastereomers of the compounds according to the invention or their mixtures. Suitable compounds according to the invention also include all possible geometrical stereoisomers (cis/trans isomers) and mixtures thereof. Cis/trans isomers may be present with respect to an alkene, carbon-nitrogen double-bond or amide group. The term “stereoisomer(s)” encompasses both optical isomers, such as enantiomers or diastereomers, the latter existing due to more than one center of chirality in the molecule, as well as geometrical isomers (cis/trans isomers). The present invention relates to every possible stereoisomer of the compounds of formula I, i.e. to single enantiomers or diastereomers, as well as to mixtures thereof.

The compounds according to the invention may be amorphous or may exist in one or more different crystalline states (polymorphs) which may have different macroscopic properties such as stability or show different biological properties such as activities. The present invention relates to amorphous and crystalline compounds according to the invention, mixtures of different crystalline states of the respective compounds according to the invention, as well as amorphous or crystalline salts thereof.

The term “tautomers” encompasses isomers, which are derived from the compounds of formula I by the shift of an H-atom involving at least one H-atom located at a nitrogen, oxygen or sulphur atom. Examples of tautomeric forms are keto-enol forms, imine-enamine forms, urea-isourea forms, thiourea-isothiourea forms, (thio)amide-(thio)imidate forms etc.

The term “stereoisomers” encompasses both optical isomers, such as enantiomers or diastereomers, the latter existing due to more than one center of chirality in the molecule, as well as geometrical isomers (cis/trans isomers).

Depending on the substitution pattern, the compounds of the formula I may have one or more centers of chirality, in which case they are present as mixtures of enantiomers or diastereomers. One center of chirality is the carbon ring atom of the isothiazoline ring carrying radical R¹. The invention provides both the pure enantiomers or diastereomers and their mixtures and the use according to the invention of the pure enantiomers or diastereomers of the compound I or its mixtures. Suitable compounds of the formula I also include all possible geometrical stereoisomers (cis/trans isomers) and mixtures thereof.

The term N-oxides relates to a form of compounds I in which at least one nitrogen atom is present in oxidized form (as NO). To be more precise, it relates to any compound of the present invention which has at least one tertiary nitrogen atom that is oxidized to an N-oxide moiety. N-oxides of compounds I can in particular be prepared by oxidizing e.g. the ring nitrogen atom of an N-heterocycle, e.g. a pyridine or pyrimidine ring present in Ar or R¹¹, or an imino-nitrogen present in central tricyclic core, with a suitable oxidizing agent, such as peroxo carboxylic acids or other peroxides. The person skilled in the art knows if and in which positions compounds of the present invention may form N-oxides.

Salts of the compounds of the formula I are preferably agriculturally and veterinarily acceptable salts. They can be formed in a customary method, e.g. by reacting the compound with an acid of the anion in question if the compound of formula I has a basic functionality or by reacting an acidic compound of formula I with a suitable base.

Suitable agriculturally or veterinarily acceptable salts are especially the salts of those cations or the acid addition salts of those acids whose cations and anions, which are known and accepted in the art for the formation of salts for agricultural or veterinary use respectively, and do not have any adverse effect on the action of the compounds according to the present invention. Suitable cations are in particular the ions of the alkali metals, preferably lithium, sodium and potassium, of the alkaline earth metals, preferably calcium, magnesium and barium, and of the transition metals, preferably manganese, copper, zinc and iron, and also ammonium (NH⁴⁺) and substituted ammonium in which one to four of the hydrogen atoms are replaced by C₁-C₄-alkyl, C₁-C₄-hydroxyalkyl, C₁-C₄-alkoxy, C₁-C₄-alkoxy-C₁-C₄-alkyl, hydroxy-C₁-C₄-alkoxy-C₁-C₄-alkyl, phenyl or —CH₂-phenyl. Examples of substituted ammonium ions comprise methylammonium, isopropylammonium, dimethylammonium, diisopropylammonium, trimethylammonium, tetramethylammonium, tetraethylammonium, tetrabutylammonium, 2-hydroxyethylammonium, 2-(2-hydroxy-ethoxy)ethylammonium, bis(2-hydroxyethyl)ammonium, benzyltrimethylammonium and benzyl-triethylammonium, furthermore phosphonium ions, sulfonium ions, preferably tri(C₁-C₄-alkyl)sulfonium, and sulfoxonium ions, preferably tri(C₁-C₄-alkyl)sulfoxonium. Suitable acid addition veterinarily acceptable salts, e.g. formed by compounds of formula I containing a basic nitrogen atom, e.g. an amino group, include salts with inorganic acids, for example hydrochlorides, sulphates, phosphates, and nitrates and salts of organic acids for example acetic acid, maleic acid, dimaleic acid, fumaric acid, difumaric acid, methane sulfenic acid, methane sulfonic acid, and succinic acid.

Anions of useful acid addition salts are primarily chloride, bromide, fluoride, hydrogen sulfate, sulfate, dihydrogen phosphate, hydrogen phosphate, phosphate, nitrate, hydrogen carbonate, carbonate, hexafluorosilicate, hexafluorophosphate, benzoate, and the anions of C₁-C₄-alkanoic acids, preferably formate, acetate, propionate and butyrate. They can be formed by reacting a compound of formulae I with an acid of the corresponding anion, preferably of hydrochloric acid, hydrobromic acid, sulfuric acid, phosphoric acid or nitric acid.

The term “invertebrate pest” as used herein encompasses animal populations, such as insects, arachnids and nematodes, which may attack plants, thereby causing substantial damage to the plants attacked, as well as ectoparasites which may infest animals, in particular warm blooded animals such as e.g. mammals or birds, or other higher animals such as reptiles, amphibians or fish, thereby causing substantial damage to the animals infested.

The term “plant propagation material” is to be understood to denote all the generative parts of the plant such as seeds and vegetative plant material such as cuttings and tubers (e. g. potatoes), which can be used for the multiplication of the plant. This includes seeds, roots, fruits, tubers, bulbs, rhizomes, shoots, sprouts and other parts of plants, including seedlings and young plants, which are to be transplanted after germination or after emergence from soil. The plant propagation materials may be treated prophylactically with a plant protection compound either at or before planting or transplanting. Said young plants may also be protected before transplantation by a total or partial treatment by immersion or pouring.

The term “plants” comprises any types of plants including “modified plants” and in particular “cultivated plants”.

The term “modified plants” refers to any wild type species or related species or related genera of a cultivated plant.

The term “cultivated plants” is to be understood as including plants which have been modified by breeding, mutagenesis or genetic engineering including but not limiting to agricultural biotech products on the market or in development (cf. http://www.bio.org/speeches/pubs/er/agri_products.asp). Genetically modified plants are plants, which genetic material has been so modified by the use of recombinant DNA techniques that under natural circumstances cannot readily be obtained by cross breeding, mutations or natural recombination. Typically, one or more genes have been integrated into the genetic material of a genetically modified plant in order to improve certain properties of the plant. Such genetic modifications also include but are not limited to targeted post-translational modification of protein(s), oligo- or polypeptides e. g. by glycosylation or polymer additions such as prenylated, acetylated or farnesylated moieties or PEG moieties.

Plants that have been modified by breeding, mutagenesis or genetic engineering, e. g. have been rendered tolerant to applications of specific classes of herbicides, such as auxin herbicides such as dicamba or2,4-D; bleacher herbicides such as hydroxylphenylpyruvate dioxygenase (HPPD) inhibitors or phytoene desaturase (PDS) inhibitors; acetolactate synthase (ALS) inhibitors such as sulfonyl ureas or imidazolinones; enolpyruvylshikimate-3-phosphate synthase (EPSPS) inhibitors, such as glyphosate; glutamine synthetase (GS) inhibitors such as glufosinate; protoporphyrinogen-IX oxidase inhibitors; lipid biosynthesis inhibitors such as acetyl CoA carboxylase (ACCase) inhibitors; or oxynil (i. e. bromoxynil or ioxynil) herbicides as a result of conventional methods of breeding or genetic engineering. Furthermore, plants have been made resistant to multiple classes of herbicides through multiple genetic modifications, such as resistance to both glyphosate and glufosinate or to both glyphosate and a herbicide from another class such as ALS inhibitors, HPPD inhibitors, auxin herbicides, or ACCase inhibitors. These herbicide resistance technologies are e. g. described in Pest Managem. Sci. 61, 2005, 246; 61, 2005, 258; 61, 2005, 277; 61, 2005, 269; 61, 2005, 286; 64, 2008, 326; 64, 2008, 332; Weed Sci. 57, 2009, 108; Austral. J. Agricult. Res. 58, 2007, 708; Science 316, 2007, 1185; and references quoted therein. Several cultivated plants have been rendered tolerant to herbicides by conventional methods of breeding (mutagenesis), e. g. Clearfield® summer rape (Canola, BASF SE, Germany) being tolerant to imidazolinones, e. g. imazamox, or ExpressSun® sunflowers (DuPont, USA) being tolerant to sulfonyl ureas, e. g. tribenuron. Genetic engineering methods have been used to render cultivated plants such as soybean, cotton, corn, beets and rape, tolerant to herbicides such as glyphosate and glufosinate, some of which are commercially available under the trade names RoundupReady® (glyphosate-tolerant, Monsanto, U.S.A.), Cultivance® (imidazolinone tolerant, BASF SE, Germany) and LibertyLink® (glufosinate-tolerant, Bayer CropScience, Germany).

Furthermore, plants are also covered that are by the use of recombinant DNA techniques capable to synthesize one or more insecticidal proteins, especially those known from the bacterial genus Bacillus, particularly from Bacillus thuringiensis, such as 5-endotoxins, e. g. CryIA(b), CryIA(c), CryIF, CryIF(a2), CryIIA(b), CryIIIA, CryIIIB(b1) or Cry9c; vegetative insecticidal proteins (VIP), e. g. VIP1, VIP2, VIP3 or VIP3A; insecticidal proteins of bacteria colonizing nematodes, e. g. Photorhabdus spp. or Xenorhabdus spp.; toxins produced by animals, such as scorpion toxins, arachnid toxins, wasp toxins, or other insect-specific neurotoxins; toxins produced by fungi, such Streptomycetes toxins, plant lectins, such as pea or barley lectins; agglutinins; proteinase inhibitors, such as trypsin inhibitors, serine protease inhibitors, patatin, cystatin or papain inhibitors; ribosome-inactivating proteins (RIP), such as ricin, maize-RIP, abrin, luffin, saporin or bryodin; steroid metabolism enzymes, such as 3-hydroxysteroid oxidase, ecdysteroid-IDP-glycosyl-transferase, cholesterol oxidases, ecdysone inhibitors or HMG-CoA-reductase; ion channel blockers, such as blockers of sodium or calcium channels; juvenile hormone esterase; diuretic hormone receptors (helicokinin receptors); stilben synthase, bibenzyl synthase, chitinases or glucanases. In the context of the present invention these insecticidal proteins or toxins are to be understood expressly also as pre-toxins, hybrid proteins, truncated or otherwise modified proteins. Hybrid proteins are characterized by a new combination of protein domains, (see, e. g. WO 02/015701). Further examples of such toxins or genetically modified plants capable of synthesizing such toxins are disclosed, e. g., in EP-A 374 753, WO 93/007278, WO 95/34656, EP-A 427 529, EP-A 451 878, WO 03/18810 und WO 03/52073. The methods for producing such genetically modified plants are generally known to the person skilled in the art and are described, e. g. in the publications mentioned above. These insecticidal proteins contained in the genetically modified plants impart to the plants producing these proteins tolerance to harmful pests from all taxonomic groups of athropods, especially to beetles (Coeloptera), two-winged insects (Diptera), and moths (Lepidoptera) and to nematodes (Nematoda). Genetically modified plants capable to synthesize one or more insecticidal proteins are, e. g., described in the publications mentioned above, and some of which are commercially available such as YieldGard® (corn cultivars producing the CryIAb toxin), YieldGard® Plus (corn cultivars producing CryIAb and Cry3Bb1 toxins), Starlink® (corn cultivars producing the Cry9c toxin), Herculex® RW (corn cultivars producing Cry34Ab1, Cry35Ab1 and the enzyme Phosphinothricin-N-Acetyltransferase [PAT]); NuCOTN® 33B (cotton cultivars producing the Cry1Ac toxin), Bollgard® I (cotton cultivars producing the Cry1Ac toxin), Bollgard® II (cotton cultivars producing Cry1Ac and Cry2Ab2 toxins); VIPCOT® (cotton cultivars producing a VIP-toxin); NewLeaf® (potato cultivars producing the Cry3A toxin); Bt-Xtra®, NatureGard®, KnockOut®, BiteGard®, Protecta®, Bt11 (e. g. Agrisure® CB) and Bt176 from Syngenta Seeds SAS, France, (corn cultivars producing the Cry1Ab toxin and PAT enyzme), MIR604 from Syngenta Seeds SAS, France (corn cultivars producing a modified version of the Cry3A toxin, c.f. WO 03/018810), MON 863 from Monsanto Europe S.A., Belgium (corn cultivars producing the Cry3Bb1 toxin), IPC 531 from Monsanto Europe S.A., Belgium (cotton cultivars producing a modified version of the Cry1Ac toxin) and 1507 from Pioneer Overseas Corporation, Belgium (corn cultivars producing the Cry1F toxin and PAT enzyme).

Furthermore, plants are also covered that are by the use of recombinant DNA techniques capable to synthesize one or more proteins to increase the resistance or tolerance of those plants to bacterial, viral or fungal pathogens. Examples of such proteins are the so-called “pathogenesis-related proteins” (PR proteins, see, e. g. EP-A 392 225), plant disease resistance genes (e. g. potato cultivars, which express resistance genes acting against Phytophthora infestans derived from the mexican wild potato Solanum bulbocastanum) or T4-lysozym (e. g. potato cultivars capable of synthesizing these proteins with increased resistance against bacteria such as Erwinia amylvora). The methods for producing such genetically modified plants are generally known to the person skilled in the art and are described, e. g. in the publications mentioned above.

Furthermore, plants are also covered that are by the use of recombinant DNA techniques capable to synthesize one or more proteins to increase the productivity (e. g. bio mass production, grain yield, starch content, oil content or protein content), tolerance to drought, salinity or other growth-limiting environmental factors or tolerance to pests and fungal, bacterial or viral pathogens of those plants.

Furthermore, plants are also covered that contain by the use of recombinant DNA techniques a modified amount of substances of content or new substances of content, specifically to improve human or animal nutrition, e. g. oil crops that produce health-promoting long-chain omega-3 fatty acids or unsaturated omega-9 fatty acids (e. g. Nexera® rape, DOW Agro Sciences, Canada).

Furthermore, plants are also covered that contain by the use of recombinant DNA techniques a modified amount of substances of content or new substances of content, specifically to improve raw material production, e. g. potatoes that produce increased amounts of amylopectin (e. g. Amflora® potato, BASF SE, Germany).

The organic moieties mentioned in the above definitions of the variables are—like the term halogen—collective terms for individual listings of the individual members. The prefix C_(n)-C_(m) indicates in each case the possible number of carbon atoms in the group.

The term halogen denotes in each case F, Br, Cl or I, in particular F, Cl or Br.

The term “alkyl” as used herein and in the alkyl moieties of alkoxy, alkylthio, and the like refers to saturated straight-chain or branched hydrocarbon radicals having 1 to 2 (“C₁-C₂-alkyl”), 1 to 3 (“C₁-C₃-alky”), 1 to 4 (“C₁-C₆-alkyl”) or 1 to 6 (“C₁-C₆-alkyl”) carbon atoms. C₁-C₂-Alkyl is CH₃ or C₂H₅. C₁-C₃-Alkyl is additionally propyl and isopropyl. C₁-C₄-Alkyl is additionally butyl, 1-methylpropyl (sec-butyl), 2-methylpropyl (isobutyl) or 1,1-dimethylethyl (tert-butyl). C₁-C₆-Alkyl is additionally also, for example, pentyl, 1-methylbutyl, 2-methylbutyl, 3-methylbutyl, 2,2-dimethylpropyl, 1-ethylpropyl, 1,1-dimethylpropyl, 1,2-dimethylpropyl, hexyl, 1-methylpentyl, 2-methylpentyl, 3-methylpentyl, 4-methylpentyl, 1,1-dimethylbutyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, 2,2-dimethylbutyl, 2,3-dimethylbutyl, 3,3-dimethylbutyl, 1-ethylbutyl, 2-ethylbutyl, 1,1,2-trimethylpropyl, 1,2,2-trimethylpropyl, 1-ethyl-1-methylpropyl, or 1-ethyl-2-methylpropyl.

The term “haloalkyl” as used herein, which is also expressed as “alkyl which is partially or fully halogenated”, refers to straight-chain or branched alkyl groups having 1 to 2 (“C₁-C₂-haloalkyl”), 1 to 3 (“C₁-C₃-haloalkyl”), 1 to 4 (“C₁-C₄-haloalkyl”) or 1 to 6 (“C₁-C₆-haloalkyl”) carbon atoms (as mentioned above), where some or all of the hydrogen atoms in these groups are replaced by halogen atoms as mentioned above: in particular C₁-C₂-haloalkyl, such as chloromethyl, bromomethyl, dichloromethyl, trichloromethyl, fluoromethyl, difluoromethyl, trifluoromethyl, chlorofluoromethyl, dichlorofluoromethyl, chlorodifluoromethyl, 1-chloroethyl, 1-bromoethyl, 1-fluoroethyl, 2-fluoroethyl, 2,2-difluoroethyl, 2,2,2-trifluoroethyl, 2-chloro-2-fluoroethyl, 2-chloro-2,2-difluoroethyl, 2,2-dichloro-2-fluoroethyl, 2,2,2-trichloroethyl or pentafluoroethyl. C₁-C₃-haloalkyl is additionally, for example, 1-fluoropropyl, 2-fluoropropyl, 3-fluoropropyl, 1,1-difluoropropyl, 2,2-difluoropropyl, 1,2-difluoropropyl, 3,3-difluoropropyl, 3,3,3-trifluoropropyl, heptafluoropropyl, 1,1,1-trifluoroprop-2-yl, 3-chloropropyl and the like. Examples for C₁-C₄-haloalkyl are, apart those mentioned for C₁-C₃-haloalkyl, 4-chlorobutyl and the like.

The term “alkylene” (or alkanediyl) as used herein in each case denotes an alkyl radical as defined above, wherein one hydrogen atom at any position of the carbon backbone is replaced by one further binding site, thus forming a bivalent moiety. Alkylene has preferably 1 to 6 carbon atoms (C₁-C₆-alkylene), 2 to 6 carbon atoms (C₂-C₆-alkylene), in particular 1 to 4 carbon atoms (C₁-C₄-alkylene) or 2 to 4 carbon atoms (C₂-C₄-alkylene). Examples of alkylene are methylene (CH₂), 1,1-ethandiyl, 1,2-ethandiyl, 1,3-propandiyl, 1,2-propandiyl, 2,2-propandiyl, 1,4-butandiyl, 1,2-butandiyl, 1,3-butandiyl, 2,3-butandiyl, 2,2-butandiyl, 1,5-pentandiyl, 2,2-dimethylpropan-1,3-diyl, 1,3-dimethyl-1,3-propandiyl, 1,6-hexandiyl etc.

The term “alkenyl” as used herein refers to monounsaturated straight-chain or branched hydrocarbon radicals having 2 to 3 (“C₂-C₃-alkenyl”), 2 to 4 (“C₂-C₄-alkenyl”) or 2 to 6 (“C₂-C₆-alkenyl) carbon atoms and a double bond in any position, for example C₂-C₃-alkenyl, such as ethenyl, 1-propenyl, 2-propenyl or 1-methylethenyl; C₂-C₄-alkenyl, such as ethenyl, 1-propenyl, 2-propenyl, 1-methylethenyl, 1-butenyl, 2-butenyl, 3-butenyl, 1-methyl-1-propenyl, 2-methyl-1-propenyl, 1-methyl-2-propenyl or 2-methyl-2-propenyl; C₂-C₆-alkenyl, such as ethenyl, 1-propenyl, 2-propenyl, 1-methylethenyl, 1-butenyl, 2-butenyl, 3-butenyl, 1-methyl-1-propenyl, 2-methyl-1-propenyl, 1-methyl-2-propenyl, 2-methyl-2-propenyl, 1-pentenyl, 2-pentenyl, 3-pentenyl, 4-pentenyl, 1-methyl-1-butenyl, 2-methyl-1-butenyl, 3-methyl-1-butenyl, 1-methyl-2-butenyl, 2-methyl-2-butenyl, 3-methyl-2-butenyl, 1-methyl-3-butenyl, 2-methyl-3-butenyl, 3-methyl-3-butenyl, 1,1-dimethyl-2-propenyl, 1,2-dimethyl-1-propenyl, 1,2-dimethyl-2-propenyl, 1-ethyl-1-propenyl, 1-ethyl-2-propenyl, 1-hexenyl, 2-hexenyl, 3-hexenyl, 4-hexenyl, 5-hexenyl, 1-methyl-1-pentenyl, 2-methyl-1-pentenyl, 3-methyl-1-pentenyl, 4-methyl-1-pentenyl, 1-methyl-2-pentenyl, 2-methyl-2-pentenyl, 3-methyl-2-pentenyl, 4-methyl-2-pentenyl, 1-methyl-3-pentenyl, 2-methyl-3-pentenyl, 3-methyl-3-pentenyl, 4-methyl-3-pentenyl, 1-methyl-4-pentenyl, 2-methyl-4-pentenyl, 3-methyl-4-pentenyl, 4-methyl-4-pentenyl, 1,1-dimethyl-2-butenyl, 1,1-dimethyl-3-butenyl, 1,2-dimethyl-1-butenyl, 1,2-dimethyl-2-butenyl, 1,2-dimethyl-3-butenyl, 1,3-dimethyl-1-butenyl, 1,3-dimethyl-2-butenyl, 1,3-dimethyl-3-butenyl, 2,2-dimethyl-3-butenyl, 2,3-dimethyl-1-butenyl, 2,3-dimethyl-2-butenyl, 2,3-dimethyl-3-butenyl, 3,3-dimethyl-1-butenyl, 3,3-dimethyl-2-butenyl, 1-ethyl-1-butenyl, 1-ethyl-2-butenyl, 1-ethyl-3-butenyl, 2-ethyl-1-butenyl, 2-ethyl-2-butenyl, 2-ethyl-3-butenyl, 1,1,2-trimethyl-2-propenyl, 1-ethyl-1-methyl-2-propenyl, 1-ethyl-2-methyl-1-propenyl, 1-ethyl-2-methyl-2-propenyl and the like.

The term “alkynyl” as used herein refers to straight-chain or branched hydrocarbon groups having 2 to 3 (“C₂-C₃-alkynyl”), 2 to 4 (“C₂-C₄-alkynyl”) or 2 to 6 (“C₂-C₆-alkynyl”) carbon atoms and one or two triple bonds in any position, for example C₂-C₃-alkynyl, such as ethynyl, 1-propynyl or 2-propynyl; C₂-C₄-alkynyl, such as ethynyl, 1-propynyl, 2-propynyl, 1-butynyl, 2-butynyl, 3-butynyl, 1-methyl-2-propynyl and the like, C₂-C₆-alkynyl, such as ethynyl, 1-propynyl, 2-propynyl, 1-butynyl, 2-butynyl, 3-butynyl, 1-methyl-2-propynyl, 1-pentynyl, 2-pentynyl, 3-pentynyl, 4-pentynyl, 1-methyl-2-butynyl, 1-methyl-3-butynyl, 2-methyl-3-butynyl, 3-methyl-1-butynyl, 1,1-dimethyl-2-propynyl, 1-ethyl-2-propynyl, 1-hexynyl, 2-hexynyl, 3-hexynyl, 4-hexynyl, 5-hexynyl, 1-methyl-2-pentynyl, 1-methyl-3-pentynyl, 1-methyl-4-pentynyl, 2-methyl-3-pentynyl, 2-methyl-4-pentynyl, 3-methyl-1-pentynyl, 3-methyl-4-pentynyl, 4-methyl-1-pentynyl, 4-methyl-2-pentynyl, 1,1-dimethyl-2-butynyl, 1,1-dimethyl-3-butynyl, 1,2-dimethyl-3-butynyl, 2,2-dimethyl-3-butynyl, 3,3-dimethyl-1-butynyl, 1-ethyl-2-butynyl, 1-ethyl-3-butynyl, 2-ethyl-3-butynyl, 1-ethyl-1-methyl-2-propynyl and the like;

The term “cycloalkyl” as used herein refers to mono- or bi- or polycyclic saturated hydrocarbon radicals having in particular 3 to 6 (“C₃-C₆-cycloalkyl”) or 3 to 5 (“C₃-C₅-cycloalkyl”) or 3 to 4 (“C₃-C₄-cycloalkyl”) carbon atoms. Examples of monocyclic radicals having 3 to 4 carbon atoms comprise cyclopropyl and cyclobutyl. Examples of monocyclic radicals having 3 to 5 carbon atoms comprise cyclopropyl, cyclobutyl and cyclopentyl. Examples of monocyclic radicals having 3 to 6 carbon atoms comprise cyclopropyl, cyclobutyl, cyclopentyl and cyclohexyl. Examples of monocyclic radicals having 3 to 8 carbon atoms comprise cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, cycloheptyl and cyclooctyl. Examples of bicyclic radicals having 7 or 8 carbon atoms comprise bicyclo[2.2.1]heptyl, bicyclo[3.1.1]heptyl, bicyclo[2.2.2]octyl and bicyclo[3.2.1]octyl. Preferably, the term cycloalkyl denotes a monocyclic saturated hydrocarbon radical.

The term “cycloalkoxy” as used herein refers to a cycloalkyl radical, in particular a monocyclic cycloalkyl radical, as defined above having in particular 3 to 6 (“C₃-C₆-cycloalkoxy”) or 3 to 5 (“C₅C₈-cycloalkoxy”) or 3 to 4 (“C₃-C₄-cycloalksoxy”) carbon atoms, which is bound via an oxygen atom to the remainder of the molecule.

The term “cycloalkyl-C₁-C₄-alkyl” refers to a C₅C₈-cycloalkyl (“C₅C₈-cycloalkyl-C₁-C₄-alkyl”), preferably a C₃-C₆-cycloalkyl (“C₃-C₆-cycloalkyl-C₁-C₄-alkyl”), more preferably a C₃-C₄-cycloalkyl (“C₃-C₄-cycloalkyl-C₁-C₄-alkyl”) as defined above (preferably a monocyclic cycloalkyl group) which is bound to the remainder of the molecule via a C₁-C₄-alkyl group, as defined above. Examples for C₃-C₄-cycloalkyl-C₁-C₄-alkyl are cyclopropylmethyl, cyclopropylethyl, cyclopropylpropyl, cyclobutylmethyl, cyclobutylethyl and cyclobutylpropyl, Examples for C₃-C₆-cycloalkyl-C₁-C₄-alkyl, apart those mentioned for C₃-C₄-cycloalkyl-C₁-C₄-alkyl, are cyclopentylmethyl, cyclopentylethyl, cyclopentyl propyl, cyclohexylmethyl, cyclohexylethyl and cyclohexylpropyl.

The term “C₁-C₂-alkoxy” is a C₁-C₂-alkyl group, as defined above, attached via an oxygen atom. The term “C₁C₃-alkoxy” is a C₁-C₃-alkyl group, as defined above, attached via an oxygen atom. The term “C₁-C₄-alkoxy” is a C₁-C₄-alkyl group, as defined above, attached via an oxygen atom. The term “C₁-C₆-alkoxy” is a C₁-C₆-alkyl group, as defined above, attached via an oxygen atom. The term “C₁C₁₀-alkoxy” is a C₁-C₁₀-alkyl group, as defined above, attached via an oxygen atom. C₁-C₂-Alkoxy is OCH₃ or OC₂H₅. C₁-C₃-Alkoxy is additionally, for example, n-propoxy and 1-methylethoxy (isopropoxy). C₁-C₄-Alkoxy is additionally, for example, butoxy, 1-methylpropoxy (sec-butoxy), 2-methylpropoxy (isobutoxy) or 1,1-dimethylethoxy (tert-butoxy). C₁-C₆-Alkoxy is additionally, for example, pentoxy, 1-methylbutoxy, 2-methylbutoxy, 3-methylbutoxy, 1,1-dimethylpropoxy, 1,2-dimethylpropoxy, 2,2-dimethylpropoxy, 1-ethylpropoxy, hexoxy, 1-methylpentoxy, 2-methylpentoxy, 3-methylpentoxy, 4-methylpentoxy, 1,1-dimethylbutoxy, 1,2-dimethylbutoxy, 1,3-dimethylbutoxy, 2,2-dimethylbutoxy, 2,3-dimethylbutoxy, 3,3-dimethylbutoxy, 1-ethylbutoxy, 2-ethylbutoxy, 1,1,2-trimethylpropoxy, 1,2,2-trimethylpropoxy, 1-ethyl-1-methylpropoxy or 1-ethyl-2-methylpropoxy. C₁-C₈-Alkoxy is additionally, for example, heptyloxy, octyloxy, 2-ethylhexyloxy and positional isomers thereof. C₁-C₁₀-Alkoxy is additionally, for example, nonyloxy, decyloxy and positional isomers thereof.

The term “C₁-C₂-haloalkoxy” is a C₁-C₂-haloalkyl group, as defined above, attached via an oxygen atom. The term “C₁-C₃-haloalkoxy” is a C₁-C₃-haloalkyl group, as defined above, attached via an oxygen atom. The term “C₁-C₄-haloalkoxy” is a C₁-C₄-haloalkyl group, as defined above, attached via an oxygen atom. The term “C₁-C₆-haloalkoxy” is a C₁-C₆-haloalkyl group, as defined above, attached via an oxygen atom. C₁-C₂-Haloalkoxy is, for example, OCH₂F, OCHF₂, OCF₃, OCH₂Cl, OCHCl₂, OCCl₃, chlorofluoromethoxy, dichlorofluoromethoxy, chlorodifluoromethoxy, 2-fluoroethoxy, 2-chloroethoxy, 2-bromoethoxy, 2-iodoethoxy, 2,2-difluoroethoxy, 2,2,2-trifluoroethoxy, 2-chloro-2-fluoroethoxy, 2-chloro-2,2-difluoroethoxy, 2,2-dichloro-2-fluoroethoxy, 2,2,2-trichloroethoxy or OC₂F₅. C₁-C₃-Haloalkoxy is additionally, for example, 2-fluoropropoxy, 3-fluoropropoxy, 2,2-difluoropropoxy, 2,3-difluoropropoxy, 2-chloropropoxy, 3-chloropropoxy, 2,3-dichloropropoxy, 2-bromopropoxy, 3-bromopropoxy, 3,3,3-trifluoropropoxy, 3,3,3-trichloropropoxy, OCH₂—C₂F₅, OCF₂—C₂F₅, 1-(CH₂F)-2-fluoroethoxy, 1-(CH₂Cl)-2-chloroethoxy or 1-(CH₂Br)-2-bromoethoxy. C₁-C₄-Haloalkoxy is additionally, for example, 4-fluorobutoxy, 4-chlorobutoxy, 4-bromobutoxy or nonafluorobutoxy. C₁-C₆-Haloalkoxy is additionally, for example, 5-fluoropentoxy, 5-chloropentoxy, 5-brompentoxy, 5-iodopentoxy, undecafluoropentoxy, 6-fluorohexoxy, 6-chlorohexoxy, 6-bromohexoxy, 6-iodohexoxy or dodecafluorohexoxy.

The term “C₁-C₆-alkoxy-C₁-C₄-alkyl” as used herein, refers to a straight-chain or branched alkyl having 1 to 4 carbon atoms, as defined above, where one hydrogen atom is replaced by a C₁-C₆-alkoxy group, as defined above. Examples are methoxymethyl, ethoxymethyl, propoxymethyl, isopropoxymethyl, n-butoxymethyl, sec-butoxymethyl, isobutoxymethyl, tert-butoxymethyl, 1-methoxyethyl, 1-ethoxyethyl, 1-propoxyethyl, 1-isopropoxyethyl, 1-n-butoxyethyl, 1-sec-butoxyethyl, 1-isobutoxyethyl, 1-tert-butoxyethyl, 2-methoxyethyl, 2-ethoxyethyl, 2-propoxyethyl, 2-isopropoxyethyl, 2-n-butoxyethyl, 2-sec-butoxyethyl, 2-isobutoxyethyl, 2-tert-butoxyethyl, 1-methoxypropyl, 1-ethoxypropyl, 1-propoxypropyl, 1-isopropoxypropyl, 1-n-butoxypropyl, 1-sec-butoxypropyl, 1-isobutoxypropyl, 1-tert-butoxypropyl, 2-methoxypropyl, 2-ethoxypropyl, 2-propoxypropyl, 2-isopropoxypropyl, 2-n-butoxypropyl, 2-sec-butoxypropyl, 2-isobutoxypropyl, 2-tert-butoxypropyl, 3-methoxypropyl, 3-ethoxypropyl, 3-propoxypropyl, 3-isopropoxypropyl, 3-n-butoxypropyl, 3-sec-butoxypropyl, 3-isobutoxypropyl, 3-tert-butoxypropyl and the like.

The term “alkoxyalkoxy” as used herein refers to an alkoxyalkyl radical, in particular a C₁-C₆-alkoxy-C₁-C₄-alkyl radical, as defined above, which is bound via an oxygen atom to the remainder of the molecule. Examples thereof are OCH₂—OCH₃, OCH₂—OC₂H₅, n-propoxymethoxy, OCH₂—OCH(CH₃)₂, n-butoxymethoxy, (1-methylpropoxy)methoxy, (2-methylpropoxy)methoxy, OCH₂—OC(CH₃)₃, 2-(methoxy)ethoxy, 2-(ethoxy)ethoxy, 2-(n-propoxy)ethoxy, 2-(1-methylethoxy)ethoxy, 2-(n-butoxy)ethoxy, 2-(1-methylpropoxy)ethoxy, 2-(2-methylpropoxy)ethoxy, 2-(1,1-dimethylethoxy)ethoxy, etc.

The substituent “oxo” replaces a CH₂ by a C(═O) group.

The term “aryl” relates to phenyl and bi- or polycyclic carbocycles having at least one fused phenylene ring, which is bound to the remainder of the molecule. Examples of bi- or polycyclic carbocycles having at least one phenylene ring include naphthyl, tetrahydronaphthyl, indanyl, indenyl, anthracenyl, fluorenyl etc.

The term “aryl-C₁-C₄-alkyl” relates to C₁-C₄-alkyl, as defined above, wherein one hydrogen atom has been replaced by an aryl radical, in particular a phenyl radical. Particular examples of aryl-C₁-C₄-alkyl include —CH₂-phenyl, 1-phenethyl, 2-phenetyl, 1-phenylpropyl, 2-phenylpropyl, 3-phenyl-1-propyl and 2-phenyl-2-propyl.

The term “aryloxy-C₁-C₄-alkyl” relates to C₁-C₄-alkyl, as defined above, wherein one hydrogen atom has been replaced by an aryloxy radical, in particular a phenoxy radical. Particular examples of aryloxy-C₁-C₄-alkyl include phenoxymethyl, 1-phenoxyethyl, 2-phenoxyetyl, 1-phenoxypropyl, 2-phenoxypropyl, 3-phenoxy-1-propyl and 2-phenoxy-2-propyl.

The term “aryl-C₁-C₄-carbonyl” relates to aryl as defined above, in particular a phenyl radical, which is bound by a carbonyl to the remainder of the molecule. Particular examples of arylcarbonyl include benzoyl, 1-naphthoyl and 2-naphthoyl.

The term “hetaryl” relates to aromatic heterocycles having either 5 or 6 ring atoms (5- or 6-membered hetaryl) and being monocyclic or 8, 9 or 10 ring atoms and bing bicyclic. Hetaryl will generally have at least one ring atom selected from O, S and N, which in case of N may be an imino-nitrogen or an amino-nitrogen, which carries hydrogen or a radical different from hydrogen. Hetaryl may have 1, 2, 3 or 4 further nitrogen atoms as ring members, which are imino nitrogens. Examples of 5- or 6-membered hetaryl include 2-furyl, 3-furyl, 2-thienyl, 3-thienyl, 1-pyrrolyl, 2-pyrrolyl, 3-pyrrolyl, 1-pyrazolyl, 3-pyrazolyl, 4-pyrazolyl, 5-pyrazolyl, 2-oxazolyl, 4-oxazolyl, 5-oxazolyl, 2-thiazolyl, 4-thiazolyl, 5-thiazolyl, 1-imidazolyl, 2-imidazolyl, 4-imidazolyl, 1,3,4-triazol-1-yl, 1,3,4-triazol-2-yl, 1,3,4-oxadiazolyl-2-yl, 1,3,4-thiadiazol-2-yl, 2-pyridinyl, 3-pyridinyl, 4-pyridinyl, 3-pyridazinyl, 4-pyridazinyl, 2-pyrimidinyl, 4-pyrimidinyl, 5-pyrimidinyl, 2-pyrazinyl and 1,3,5-triazin-2-yl. Examples of 8-, 9- or 10-membered hetaryl include, for example, quinolinyl, isoquinolinyl, cinnolinyl, indolyl, indolizynyl, isoindolyl, indazolyl, benzofuryl, benzothienyl, benzo[b]thiazolyl, benzoxazolyl, benzthiazolyl, benzimidazolyl, imidazo[1,2-a]pyridine-2-yl, thieno[3,2-b]pyridine-5-yl, imidazo-[2,1-b]-thiazol-6-yl and 1,2,4-triazolo[1,5-a]pyridine-2-yl.

Examples of N-bound 5-, 6-, 7 or 8-membered saturated heterocycles include: pyrrolidin-1-yl, pyrazolidin-1-yl, imidazolidin-1-yl, oxazolidin-3-yl, isoxazolidin-2-yl, thiazolidin-3-yl, isothiazolidin-2-yl, piperidin-1-yl, piperazin-1-yl, morpholin-4-yl, thiomorpholin-4-yl, 1-oxothiomorpholin-4-yl, 1,1-dioxothiomorpholin-4-yl, azepan-1-yl and the like.

The term “hetaryl-C₁-C₄-alkyl” relates to C₁-C₄-alkyl, as defined above, wherein one hydrogen atom has been replaced by a hetaryl radical, in particular a pyridyl radical. Particular examples of hetaryl-C₁-C₄-alkyl include 2-pyridylmethyl, 3-pyridylmethyl, 4-pyridylmethyl, 1-(2-pyridyl)ethyl, 2-(2-pyridyl)ethyl, 1-(3-pyridyl)ethyl, 2-(3-pyridyl)ethyl, 1-(4-pyridyl)ethyl, 2-(4-pyridyl)ethyl etc.

The term “hetaryloxy-C₁-C₄-alkyl” relates to C₁-C₄-alkyl, as defined above, wherein one hydrogen atom has been replaced by an hetaryloxy radical, in particular a pyridyloxy radical. Particular examples of hetaryloxy-C₁-C₄-alkyl include 2-pyridyloxymethyl, 3-pyridyloxymethyl, 4-pyridyloxymethyl, 1-(2-pyridyloxy)ethyl, 2-(2-pyridyloxy)ethyl, 1-(3-pyridyloxy)ethyl, 2-(3-pyridyloxy)ethyl, 1-(4-pyridyloxy)ethyl, 2-(4-pyridyloxy)ethyl etc.

The term “hetaryl-C₁-C₄-carbonyl” relates to hetaryl as defined above, in particular a C-bound hetaryl radical, e.g. 2-, 3- or 4-pyridyl, 2- or 3-thienyl, 2- or 3-furyl, 1-, 2- or 3-pyrrolyl, 2- or 4-pyrimidinyl, pyridazinyl, 1-, 3- or 4-pyrazolyl, 1-, 2- or 4-imidazolyl radical, which is bound by a carbonyl to the remainder of the molecule.

The term “substituted” if not specified otherwise refers to substituted with 1, 2 or maximum possible number of substituents. If substituents as defined in compounds of formula I are more than one then they are independently from each other are same or different if not mentioned otherwise.

In one preferred embodiment, A¹ is N, A² is CR^(A2), A³ is CR^(A3);

In another preferred embodiment, A¹ is CR^(A1), A² is N, A³ is CR^(A3);

In another preferred embodiment, A¹ is CR^(A1), A² is CR^(A2), A³ is N;

In another preferred embodiment, A¹ is N, A² is N, A³ is CR^(A3);

In another preferred embodiment, A¹ is N, A² is CR^(A2), A³ is N;

In another preferred embodiment, A¹ is CR^(A1), A² is N, A³ is N;

In one preferred embodiment, B¹ is CR^(B1), B² is CR^(B2), B³ is CR^(B3);

In another preferred embodiment, B¹ is N, B² is CR^(B2), B³ is CR^(B3);

In another preferred embodiment, B¹ is CR^(B1), B² is N, B³ is CR^(B3);

In another preferred embodiment, B¹ is N, B² is N, B³ is CR^(B3);

In another preferred embodiment, B¹ is N, B² is N, B³ is N;

In another preferred embodiment, A¹ is N, A² is CR^(A2), A³ is CR^(A3), B¹ is CR^(B1), B² is CR^(B2), B³ is CR^(B3);

In another preferred embodiment, A¹ is N, A² is CR^(A2), A³ is CR^(A3), B¹ is N, B² is CR^(B2), B³ is CR^(B3);

In another preferred embodiment, A¹ is N, A² is CR^(A2), A³ is CR^(A3), B¹ is CR^(B1), B² is N, B³ is CR^(B3);

In another preferred embodiment, A¹ is N, A² is CR^(A2), A³ is CR^(A3), B¹ is N, B² is N, B³ is CR^(B3);

In another preferred embodiment, A¹ is N, A² is CR^(A2), A³ is CR^(A3), B¹ is N, B² is N, B³ is N;

In another preferred embodiment, A¹ is CR^(A1), A² is N, A³ is CR^(A3), B¹ is CR^(B1), B² is CR^(B2), B³ is CR^(B3);

In another preferred embodiment, A¹ is CR^(A1), A² is N, A³ is CR^(A3), B¹ is N, B² is CR^(B2), B³ is CR^(B3);

In another preferred embodiment, A¹ is CR^(A1), A² is N, A³ is CR^(A3), B¹ is CR^(B1), B² is N, B³ is CR^(B3);

In another preferred embodiment, A¹ is CR^(A1), A² is N, A³ is CR^(A3), B¹ is N, B² is N, B³ is CR^(B3);

In another preferred embodiment, A¹ is CR^(A1), A² is N, A³ is CR^(A3), B¹ is N, B² is N, B³ is N;

In another preferred embodiment, A¹ is CR^(A1), A² is CR^(A2), A³ is N, B¹ is CR^(B1), B² is CR^(B2), B³ is CR^(B3);

In another preferred embodiment, A¹ is CR^(A1), A² is CR^(A2), A³ is N, B¹ is N, B² is CR^(B2), B³ is CR^(B3);

In another preferred embodiment, A¹ is CR^(A1), A² is CR^(A2), A³ is N, B¹ is CR^(B1), B² is N, B³ is CR^(B3);

In another preferred embodiment, A¹ is CR^(A1), A² is CR^(A2), A³ is N, B¹ is N, B² is N, B³ is CR^(B3);

In another preferred embodiment, A¹ is CR^(A1), A² is CR^(A2), A³ is N, B¹ is N, B² is N, B³ is N;

In another preferred embodiment, A¹ is N, A² is N, A³ is CR^(A3), B¹ is CR^(B1), B² is CR^(B2), B³ is CR^(B3);

In another preferred embodiment, A¹ is N, A² is N, A³ is CR^(A3), B¹ is N, B² is CR^(B2), B³ is CR^(B3);

In another preferred embodiment, A¹ is N, A² is N, A³ is CR^(A3), B¹ is CR^(B1), B² is N, B³ is CR^(B3);

In another preferred embodiment, A¹ is N, A² is N, A³ is CR^(A3), B¹ is N, B² is N, B³ is CR^(B3);

In another preferred embodiment, A¹ is N, A² is N, A³ is CR^(A3), B¹ is N, B² is N, B³ is N;

In another preferred embodiment, A¹ is N, A² is CR^(A2), A³ is N, B¹ is CR^(B1), B² is CR^(B2), B³ is CR^(B3);

In another preferred embodiment, A¹ is N, A² is CR^(A2), A³ is N, B¹ is N, B² is CR^(B2), B³ is CR^(B3);

In another preferred embodiment, A¹ is N, A² is CR^(A2), A³ is N, B¹ is CR^(B1), B² is N, B³ is CR^(B3);

In another preferred embodiment, A¹ is N, A² is CR^(A2), A³ is N, B¹ is N, B² is N, B³ is CR^(B3);

In another preferred embodiment, A¹ is N, A² is CR^(A2), A³ is N, B¹ is N, B² is N, B³ is N;

In one preferred embodiment, R^(A1), R^(A2), R^(A3) independently of each other are selected from H, halogen, OH, CN, C₁-C₆-alkyl, C₁-C₆-alkoxy, tri-C₁-C₆-alkylsilyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl, wherein the alkyl, alkoxy, cycloalkyl moieties are unsubstituted or substituted with halogen,

C(═O)—OR^(a), NR^(b)R^(c), C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), and S(═O)_(m)R^(e);

In another preferred embodiment, R^(A1), R^(A2), R^(A3) independently of each other are selected from H, halogen, C₁-C₆-alkyl, and C₃-C₆-cycloalkyl, wherein the alkyl or cycloalkyl moieties are unsubstituted or substituted with halogen.

In another preferred embodiment, R^(A1), R^(A2), R^(A3) independently of each other are selected from H, Cl, Br, F, CH₃, C₂H₅, n-C₃H₇, isopropyl, cyclopropyl, CH₂F, CHF₂, and CF₃.

In another preferred embodiment, R^(A1), R^(A2), R^(A3) are H.

In one preferred embodiment, R^(B1), R^(B2), R^(B3) independently of each other are H, halogen, or C₁-C₆-alkyl;

In another preferred embodiment, R^(B1), R^(B2), R^(B3) independently of each other are H, Cl, Br, F, CH₃, C₂H₅, n-C₃H₇, or isopropyl.

In another preferred embodiment, R^(B1), R^(B2), R^(B3) independently of each other are H, or CH₃.

In another preferred embodiment, R^(B1), R^(B2), R^(B3) are H.

In one preferred embodiment, Q is —C(R⁴R⁵)—O—, wherein C is bound to Ar.

In another preferred embodiment, Q is —C(R⁴R⁵)—O—, wherein O is bound to Ar.

In another preferred embodiment, Q is —C(═O)—O—, wherein C is bound to Ar.

In another preferred embodiment, Q is —C(═O)—O—, wherein O is bound to Ar.

In another preferred embodiment, Q is —S(═O)_(m)—C(R⁷R⁸)—, wherein S is bound to Ar.

In another preferred embodiment, Q is —S(═O)_(m)—C(R⁷R⁸)—, wherein C is bound to Ar.

In another preferred embodiment, Q is —N(R²)—S(═O)_(m)—, wherein N is bound to Ar.

In another preferred embodiment, Q is —N(R²)—S(═O)_(m)—, wherein S is bound to Ar.

In another preferred embodiment, Q is —N(R²)—C(R⁹R¹⁰)—, wherein N is bound to Ar.

In another preferred embodiment, Q is —N(R²)—C(R⁹R¹⁰)—, wherein C is bound to Ar.

In another preferred embodiment, Q is —C(═O)—C(R¹⁹R²⁰)—, wherein C(═O) is bound to Ar.

In another preferred embodiment, Q is —C(═O)—C(R¹⁹R²⁰)—, wherein C(R¹⁹R²⁰) is bound to Ar.

In another preferred embodiment, Q is —N(R²)—C(═O)—, wherein N is bound to Ar.

In another preferred embodiment, Q is —N(R²)—C(═O)—, wherein C is bound to Ar.

In another preferred embodiment, Q is —N(R²)—C(═S)—, wherein N is bound to Ar.

In another preferred embodiment, Q is —N(R²)—C(═S)—, wherein C is bound to Ar.

In another preferred embodiment, Q is —N═C(X)—, wherein N is bound to Ar.

In another preferred embodiment, Q is —N═C(X)—, wherein C is bound to Ar.

In another preferred embodiment, Q is —N(R²)—C(═NR)—, wherein N is bound to Ar.

In another preferred embodiment, Q is —N(R²)—C(═NR)—, wherein C is bound to Ar.

In another preferred embodiment, Q is —C(R¹³R¹⁴)—C(R¹⁵R¹⁶)—.

In another preferred embodiment, Q is —C(R¹⁷)═C(R¹⁸)—.

In another preferred embodiment, Q is —C(R⁴R⁵)—O—, —N(R²)—S(═O)_(m)—, —N(R²)—C(R⁹R¹⁰)—, —N(R²)—C(═O)—, —N(R²)—C(═S)—, —N═C(X)—, or —N(R²)—C(═NR)—, wherein Ar is bound to either side of Q;

In another preferred embodiment, Q is —C(R⁴R⁵)—O—, —N(R²)—C(R⁹R¹⁰)—, —N(R²)—C(═O)—, —N(R²)—C(═NR)—, wherein Ar is bound to either side of Q;

In another preferred embodiment, Q is —C(R⁴R⁵)—O—, —N(R²)—C(R⁹R¹⁰)—, or —N(R²)—C(═O)—, wherein Ar is bound to either side of Q;

In another preferred embodiment, Q is-N(R²)—C(R⁹R¹⁰)—, wherein C is bound to Ar, or —N(R²)—C(═O)—, wherein N is bound to Ar, or —C(R⁴R⁵)—O—, wherein C is bound to Ar;

In one preferred embodiment, X is H or N(R³)₂;

In another preferred embodiment, X is H;

In another preferred embodiment, X is N(R³)₂;

In one preferred embodiment, R³ is C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, or C₃-C₆-cycloalkoxy-C₁-C₄-alkyl, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,

C₁-C₆-alkylene-CN, phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f);

In another preferred embodiment, R³ is H, C₁-C₆-alkyl, or C₁-C₆-alkoxy-C₁-C₄-alkyl;

In another preferred embodiment, R³ is H, or C₁-C₆-alkyl;

In another preferred embodiment, R³ is C₁-C₆-alkyl;

In another preferred embodiment, R³ is H;

In one preferred embodiment, R is H, CN, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₂-C₆-alkenyl, C₂-C₆-haloalkenyl, C₂-C₆-alkynyl, C₂-C₆-haloalkynyl, C₃-C₆-cycloalkyl, C₃-C₆-halocycloalkyl, OR⁸, or N(R³)₂;

In another preferred embodiment, R is H, CN, C₁-C₆-alkyl, or OR⁸;

In another preferred embodiment, R is H, or C₁-C₆-alkyl;

In another preferred embodiment, R is H, CH₃, C₂H₅, n-C₃H₇, or isopropyl;

In one preferred embodiment, R⁶ is H, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,

C(═O)—OR^(a), C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN, C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), S(═O)_(m)R^(e), phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f);

In another preferred embodiment, R⁶ is H, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,

In another preferred embodiment, R⁶ is C(═O)—OR^(a), C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN, C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), S(═O)_(m)R^(e), phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f);

In another preferred embodiment, R⁶ is H, C₁-C₆-alkyl, C₁-C₆-haloalkyl, —CH₂—C(═O)—OR^(a), or —CH₂-phenyl;

In another preferred embodiment, R⁶ is H, C₁-C₆-alkyl, C₁-C₆-haloalkyl, or —CH₂-phenyl;

In another preferred embodiment, R⁶ is H, C₁-C₆-alkyl, C₁-C₆-haloalkyl, or —CH₂—C(═O)—OR^(a);

In another preferred embodiment, R⁶ is H, C₁-C₆-alkyl, or C₁-C₆-haloalkyl;

In another preferred embodiment, R⁶ is H;

In another preferred embodiment, R⁶ is C₁-C₆-alkyl;

In another preferred embodiment, R⁶ is C₁-C₆-haloalkyl;

In another preferred embodiment, R⁶ is H, CH₃, C₂H₅, CH₂CF₃, or CHF₂;

In another preferred embodiment, R⁶ is H, CH₃, C₂H₅, or CH₂CF₃;

In one preferred embodiment, R⁴, R⁵, R⁷, R⁸, R⁹, R¹⁰, R¹³, R¹⁴, R¹⁵, R¹⁶, R¹⁷, R¹⁸, R¹⁹, R²⁰ are, identical or different, H, halogen, C₁-C₆-alkyl, C₁-C₆-haloalkylalkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl, C₃-C₆-halocycloalkyl, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl, C(═O)—OR^(a), C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), S(═O)_(m)R^(e), phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f);

In another preferred embodiment, R⁴, R⁵, R⁷, R⁸, R⁹, R¹⁰, R¹³, R¹⁴, R¹⁵, R¹⁶, R¹⁷, R¹⁸, R¹⁹, R²⁰ are, identical or different, H, halogen, C₁-C₆-alkyl, C₁-C₆-haloalkylalkyl, C₃-C₆-cycloalkyl, C₃-C₆-halocycloalkyl, C(═O)—OR^(a), C(═O)—NR^(b)R^(c), C(═O)—R^(d), phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f);

In another preferred embodiment, R⁴, R⁵, R⁷, R⁸, R⁹, R¹⁰, R¹³, R¹⁴, R¹⁵, R¹⁶, R¹⁷, R¹⁸, R¹⁹, R²⁰ are, identical or different, H, halogen, C₁-C₆-alkyl, or C₁-C₆-haloalkylalkyl;

In another preferred embodiment, R⁴, R⁵, R⁷, R⁸, R⁹, R¹⁰, R¹³, R¹⁴, R¹⁵, R¹⁶, R¹⁷, R¹⁸, R¹⁹, R²⁰ are, identical or different, H, halogen, or C₁-C₆-alkyl;

In another preferred embodiment, R⁴, R⁵, R⁷, R⁸, R⁹, R¹⁰, R¹³, R¹⁴, R¹⁵, R¹⁶, R¹⁷, R¹⁸, R¹⁹, R²⁰ are, identical or different, H or C₁-C₆-alkyl;

In one preferred embodiment, Ar is phenyl which is unsubstituted or substituted with R^(Ar).

In another preferred embodiment, Ar is 5- or 6-membered hetaryl, which is unsubstituted or substituted with R^(Ar).

In more preferred embodiment, Ar is phenyl, pyrimidinyl, pyridazinyl, or pyridyl, which are unsubstituted or substituted with R^(Ar).

In one preferred embodiment, R^(Ar) is halogen, OH, CN, NO₂, SCN, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy, or S—R^(e).

In more preferred embodiment, R^(Ar) is F, Cl, Br, OH, CN, NO₂, SCN, CH₃, C₂H₅, n-C₃H₇, isopropyl, CH₂F, CHF₂, CF₃, CH₂CF₃, CF₂CHF₂, C₂F₅, CH₂CH₂CF₃, CH₂CF₂CHF₂, CH₂CF₂CF₃, OCH₃, OC₂H₅, n-propyloxy, isopropyloxy, OCH₂F, OCHF₂, OCF₃, OCH₂CF₃, OCF₂CHF₂, OC₂F₅, OCH₂CH₂CF₃, OCH₂CF₂CHF₂, OCH₂CF₂CF₃, or S—R^(e), where R^(e) is C₁-C₆-alkyl, in particular C₁-C₃-alkyl such as CH₃, C₂H₅, n-C₃H₇ or isopropyl, or C₁-C₆-haloalkyl, in particular fluorinated C₁-C₃-alkyl such as CH₂F, CHF₂, CF₃, CH₂CF₃, CF₂CHF₂, C₂F₅, CH₂CH₂CF₃, CH₂CF₂CHF₂ or CH₂CF₂CF₃.

Particularly preferred Ar are listed in Table A below.

TABLE A Ar-1 

Ar-2 

Ar-3 

Ar-4 

Ar-5 

Ar-6 

Ar-7 

Ar-8 

Ar-9 

Ar-10

Ar-11

Ar-12

Ar-13

Ar-14

Ar-15

Ar-16

Ar-17

Ar-18

Ar-19

Ar-20

Particularly preferred Ar is selected from Ar-1 to Ar-20;

also particularly preferred Ar is selected from Ar-1 to Ar-13;

also particularly preferred Ar is selected from Ar-1 to Ar-13 and Ar-17 to Ar-18;

also particularly preferred Ar is selected from Ar-1, Ar-2, Ar-3, Ar-4, Ar-10, Ar-17, and Ar-18.

also particularly preferred Ar is Ar-2;

also particularly preferred Ar is selected from Ar-17 and Ar-18;

also particularly preferred Ar is Ar-17;

also particularly preferred Ar is Ar-18;

In one preferred embodiment, R¹ is Y—Z-T-R¹¹.

In another preferred embodiment, R¹ is Y—Z-T-R¹².

In one preferred embodiment, Y is —CR^(ya)═N—, wherein the N is bound to Z.

In another preferred embodiment, Y is —NR^(yc)—C(═S)—, wherein C(═S) is bound to Z.

In another preferred embodiment, Y is —NR^(yc)—C(═O)—, wherein C(═O) is bound to Z.

In one preferred embodiment, Z is a single bond;

—NR^(zc)—C(═O)—, wherein C(═O) is bound to T;

—NR^(zc)—C(═S)—, wherein C(═S) is bound to T;

—N═C(S—R^(za))—, wherein T is bound to the carbon atom; or

—NR^(zc)—C(S—R^(za))═, wherein T is bound to the carbon atom;

In another preferred embodiment, Z is —NR^(zc)—C(═S)—, wherein C(═S) is bound to T.

In another preferred embodiment, Z is —NR^(zc)—C(═O)—, wherein C(═O) is bound to T.

In another preferred embodiment, Z is-N═C(S—R^(za))—, wherein T is bound to the carbon atom.

In another preferred embodiment, Z is-NR^(zc)—C(S—R^(za))═, wherein T is bound to the carbon atom.

In another preferred embodiment, Z is —O—C(═O)—, wherein T is bound to the carbon atom;

In another preferred embodiment, Z is a single bond.

In one preferred embodiment, T is O.

In another preferred embodiment, T is N—R^(T).

In another preferred embodiment, T is N.

In one preferred embodiment, R^(ya) is H, halogen, C₁-C₆-alkyl, C₁-C₆-alkoxy, which are unsubstituted or substituted with halogen,

phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f).

In more preferred embodiment, R^(ya) is H, halogen, C₁-C₆-alkyl, C₁-C₆-alkoxy, which are unsubstituted or substituted with halogen,

or phenyl which is unsubstituted or substituted with R^(f).

In most preferred embodiment, R^(ya) is H, F, Cl, Br, CH₃, C₂H₅, n-C₃H₇, isopropyl, CH₂F, CHF₂, CF₃, CH₂CF₃, CF₂CHF₂, C₂F₅, CH₂CH₂CF₃, CH₂CF₂CHF₂, CH₂CF₂CF₃, OCH₃, OC₂H₅, n-propyloxy, isopropyloxy, OCH₂F, OCHF₂, OCF₃, OCH₂CF₃, OCF₂CHF₂, OC₂F₅, OCH₂CH₂CF₃, OCH₂CF₂CHF₂, OCH₂CF₂CF₃, or phenyl which is unsubstituted or substituted with R^(f).

In further most preferred embodiment, R^(ya) is H or CH₃;

In one embodiment, R^(yc), R^(zc) independently are H, C₁-C₆-alkyl, C₃-C₆-cycloalkyl, which are unsubstituted or substituted with halogen,

phenyl, or —CH₂-phenyl, wherein the rings are unsubstituted or substituted with R^(f).

In more preferred embodiment, R^(yc) and R^(zc) are H, C₁-C₆-alkyl, C₁-C₆-haloalkyl, or phenyl which is unsubstituted or substituted with R^(f).

In most preferred embodiment, R^(yc) and R^(zc) are H, CH₃, C₂H₅, n-C₃H₇, isopropyl, CH₂F, CHF₂, CF₃, CH₂CF₃, CF₂CHF₂, C₂F₅, CH₂CH₂CF₃, CH₂CF₂CHF₂, CH₂CF₂CF₃, or phenyl which is unsubstituted or substituted with R^(f).

In further most preferred embodiment, R^(yc) and R^(zc) are H or CH₃;

In one preferred embodiment, R^(T) is H, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₄-alkyl-C₁-C₆-alkoxy, which are unsubstituted or substituted with halogen,

C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), S(═O)_(m)R^(e), phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f).

In more preferred embodiment, R^(T) is H, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₄-alkyl-C₁-C₆-alkoxy, which are unsubstituted or substituted with halogen.

In most preferred embodiment, R^(T) is H or C₁-C₆-alkyl.

In another preferred embodiment, R^(zc) together with R^(T) if present, forms C₁-C₆-alkylene or a linear C₂-C₆-alkenylene group, where in the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene a CH₂ moiety may be replaced by a carbonyl or a C═N—R′ and/or wherein 1 or 2 CH₂ moieties may be replaced by O or S and/or wherein the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene may be unsubstituted or substituted with R^(h).

In more preferred embodiment, R^(zc) together with R^(T) if present, forms C₁-C₆-alkylene or a linear C₂-C₆-alkenylene group, where in the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene a CH₂ moiety is replaced by a carbonyl group.

In another more preferred embodiment, R^(zc) together with R^(T) if present, forms C₁-C₆-alkylene or a linear C₂-C₆-alkenylene group, where in the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene a CH₂ moiety is replaced by a C═N—R′ and wherein 1 or 2 CH₂ moieties may be replaced by O or S and/or wherein the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene may be unsubstituted or substituted with R^(h).

In another more preferred embodiment, R^(zc) together with R^(T) if present, forms C₁-C₆-alkylene or a linear C₂-C₆-alkenylene group, where in the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene 1 or 2 CH₂ moieties are replaced by O or S and/or wherein the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene may be unsubstituted or substituted with R^(h).

In one preferred embodiment, R^(za) is H, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆—C(═O)—R^(d), phenyl, phenylcarbonyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f);

In more preferred embodiment, R^(za) is H, C₁-C₆-alkyl, or C₁-C₆-haloalkyl;

In most preferred embodiment, R^(za) is H, C₁-C₆-alkyl.

In another preferred embodiment, R^(za) together with R^(T) if present, forms C₁-C₆-alkylene or a linear C₂-C₆-alkenylene group, where in the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene a CH₂ moiety may be replaced by a carbonyl or a C═N—R′ and/or wherein 1 or 2 CH₂ moieties may be replaced by O or S and/or wherein the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene may be unsubstituted or substituted with R^(h);

In more preferred embodiment, R^(za) together with R^(T) if present, forms C₁-C₆-alkylene or a linear C₂-C₆-alkenylene group, where in the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene a CH₂ moiety is replaced by a carbonyl group.

In another more preferred embodiment, R^(za) together with R^(T) if present, forms C₁-C₆-alkylene or a linear C₂-C₆-alkenylene group, where in the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene a CH₂ moiety is replaced by a C═N—R′ and wherein 1 or 2 CH₂ moieties may be replaced by O or S and/or wherein the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene may be unsubstituted or substituted with R^(h).

In another more preferred embodiment, R^(za) together with R^(T) if present, forms C₁-C₆-alkylene or a linear C₂-C₆-alkenylene group, where in the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene 1 or 2 CH₂ moieties are replaced by O or S and/or wherein the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene may be unsubstituted or substituted with R^(h).

In a preferred embodiment, R^(a), R^(b) and R^(c) are H, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, which are unsubstituted or substituted with halogen,

C₁-C₆-alkylene-CN, phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f);

In more preferred embodiment, R^(a), R^(b) and R^(c) are H, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, which are unsubstituted or substituted with halogen,

phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f).

In a preferred embodiment, R^(d) is H, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, which are unsubstituted or substituted with halogen,

phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f).

In more preferred embodiment, R^(d) is H, C₁-C₆-alkyl, C₁-C₆-haloalkyl, or phenyl which is unsubstituted or substituted with R^(f).

In one preferred embodiment, R^(e) is C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₃-C₆-cycloalkyl, C₃-C₆-halocycloalkyl, phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f).

In more preferred embodiment, R^(e) is H, C₁-C₆-alkyl, C₁-C₆-haloalkyl, or phenyl unsubstituted or substituted with R^(f).

In one preferred embodiment, R^(f) is halogen, N3, OH, CN, NO₂, —SCN, —SF₅, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkoxy, which are unsubstituted or substituted with halogen,

C(═O)—OR^(a), NR^(b)R^(c), C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN, C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), or S(═O)_(m)R^(e).

In more preferred embodiment, R^(f) is halogen, N3, OH, CN, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkoxy, which are unsubstituted or substituted with halogen,

C(═O)—OR^(a), NR^(b)R^(c), C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN, C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), or S(═O)_(m)R^(e).

In a preferred embodiment, R⁹ is halogen, N3, OH, CN, NO₂, —SCN, —SF₅, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkoxy, which are unsubstituted or substituted with halogen,

C(═O)—OR^(a), NR^(b)R^(c), C₁-C₆-alkylene-NR^(b)R^(c), NH—C₁-C₆-alkylene-NR^(b)R^(c), C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), or S(═O)_(m)R^(e).

In more preferred embodiment, R⁹ is halogen, N₃, OH, CN, NO₂, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkoxy, which are unsubstituted or substituted with halogen,

C(═O)—OR^(a), NR^(b)R^(c), C₁-C₆-alkylene-NR^(b)R^(c), C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), or S(═O)_(m)R^(e).

In one embodiment, m is 0.

In another embodiment, m is 1.

In another embodiment, m is 2.

In another embodiment, m is 0 or 1.

In another embodiment, m is 1 or 2.

In more preferred embodiment, R¹ are formulas Y-1 to Y-9 wherein

denotes attachment to the 10 membered hetaryl, D is R¹¹ or R¹² and wherein R^(T), R¹¹, R¹², R^(ya), R^(yc), R^(za) and R^(zc) are as defined in compounds of formula I.

In more preferred embodiment, R¹ are formulas Y-1 to Y-8 wherein

denotes attachment to the 10 membered hetaryl, D is R¹¹ or R¹² and wherein R^(T), R¹¹, R¹², R^(ya), R^(yc), R^(za) and R^(zc) are as defined in compounds of formula I.

In another more preferred embodiment, R¹ are formulas YZT-1 to YZT-9, wherein

denotes attachment to the 10 membered hetaryl and R¹¹, R¹², R^(T), R^(ya), R^(za) and R^(zc) are as defined in compounds of formula I.

In another more preferred embodiment, R¹ are formulas YZT-1 to YZT-8, wherein

denotes attachment to the 10 membered hetaryl and R¹¹, R¹², R^(T), R^(ya), R^(za) and R^(zc) are as defined in compounds of formula I.

In another more preferred embodiment, R¹ are formulas YZT-1, YZT-5, YZT-6, or YZT-8, wherein

denotes attachment to the 10 membered hetaryl and R¹¹, R¹², R^(T), R^(ya), R^(za) and R^(zc) are as defined in compounds of formula I.

In most preferred embodiment, R¹ are formulas Y-1A to Y-9A, wherein

denotes attachment to the 10 membered hetaryl, D is R¹¹ or R¹².

In most preferred embodiment, R¹ are formulas Y-1A to Y-8B, wherein

denotes attachment to the 10 membered hetaryl, D is R¹¹ or R¹².

In most preferred embodiment, R¹ are formulas Y-1 A, Y-5A, Y-6A, or Y-8A, wherein

denotes attachment to the 10 membered hetaryl, D is R¹¹ or R¹².

In one preferred embodiment, R¹¹ is C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₁-C₄-alkyl-C₃-C₆-cycloalkoxy, which are unsubstituted or substituted with halogen,

aryl, arylcarbonyl, aryl-C₁-C₄-alkyl, aryloxy-C₁-C₄-alkyl, hetaryl, carbonylhetaryl, C₁-C₄-alkyl-hetaryl and C₁-C₄-alkyl-hetaryloxy, wherein the aryl or hetaryl rings are unsubstituted or substituted with R^(g) and wherein the hetaryl is a 5- or 6-membered monocyclic hetaryl or a 8-, 9- or 10-membered bicyclic hetaryl.

In more preferred embodiment, R¹¹ is C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₃-C₆-cycloalkyl, which are unsubstituted or substituted with halogen,

aryl, arylcarbonyl, aryl-C₁-C₄-alkyl, aryloxy-C₁-C₄-alkyl, hetaryl, carbonylhetaryl, C₁-C₄-alkyl-hetaryl and C₁-C₄-alkyl-hetaryloxy, where the rings are unsubstituted or substituted with R^(g) and wherein the hetaryl is a 5- or 6-membered monocyclic hetaryl or a 8-, 9- or 10-membered bicyclic hetaryl.

In most preferred embodiment, R¹¹ is aryl, aryl-C₁-C₄-alkyl, hetaryl, or hetaryl-C₁-C₄-alkyl, wherein the rings are unsubstituted or substituted with R^(g) and where hetaryl in hetaryl or hetaryl-C₁-C₄-alkyl, is preferably a 5- or 6-membered monocyclic hetaryl such as pyridyl, pyrimidinyl, pyridazinyl, pyrrolyl, pyrazolyl, imidazolyl, oxazolyl, thiazolyl, isoxazolyl or isothiazolyl which is unsubstituted or substituted with R⁹.

Examples of particularly preferred radicals R¹¹ are the radicals R¹¹-1 to R¹¹-29 summarized in Table A-1 below.

TABLE A-1 R¹¹-1 

R¹¹-2 

R¹¹-3 

R¹¹-4 

R¹¹-5 

R¹¹-6 

R¹¹-7 

R¹¹-8 

R¹¹-9 

R¹¹-10

R¹¹-11

R¹¹-12

R¹¹-13

R¹¹-14

R¹¹-15

R¹¹-16

R¹¹-17

R¹¹-18

R¹¹-19

R¹¹-20

R¹¹-21

R¹¹-22

R¹¹-23

R¹¹-24

R¹¹-25

R¹¹-26

R¹¹-27

R¹¹-28

R¹¹-29

In another preferred embodiment, R¹¹ is R¹¹-1 or R¹¹-29;

In another preferred embodiment, R¹¹ is R¹¹-1;

In one embodiment, R¹² is a radical of the formula (A¹),

-   -   wherein # indicates the point of attachment to T and wherein         R¹²¹, R¹²², R¹²³ and R¹²⁴ are as defined above and wherein R¹²¹,         R¹²², R¹²³ and R¹²⁴ independently of each other and especially         in combination preferably have the following meanings:         -   R¹²¹ is C₁-C₄-alkoxy, in particular OCH₃, OC₂H₅;         -   R¹²² is C₁-C₄-alkoxy, such as OCH₃, OC₂H₅, n-propoxyx or             isopropoxy, or C₃-C₄-alkenyloxy, such as allyloxy, with R¹²²             in particular being OCH₃, OC₂H₅, or n-propoxy;         -   R¹²³ is OH, C₁-C₄-alkoxy, such as OCH₃, OC₂H₅, or             C₃-C₄-alkenyloxy, such as allyloxy, with R¹²³ in particular             being OCH₃, OC₂H₅;         -   R¹²⁴ is C₁-C₄-alkyl, such as CH₃ or C₂H₅, or             C₁-C₄-alkoxy-C₁-C₄-alkyl, such as methoxymethyl,             ethoxymethyl, 2-methoxyethyl or 2-ethoxyethyl, with R¹²⁴ in             particular being methyl.

In more preferred embodiment, R¹² is in particular a radical of the formula (A¹¹), e.g. (A¹¹-a) or (A¹¹-b)

-   -   wherein # indicates the point of attachment to T and wherein         R¹²¹, R¹²², R¹²³ and R¹²⁴ are as defined above and wherein R¹²¹,         R¹²², R¹²³ and R¹²⁴ independently of each other and especially         in combination preferably have the following meanings:         -   R¹²¹ is C₁-C₄-alkoxy, in particular OCH₃ or OC₂H₅;         -   R¹²² is C₁-C₄-alkoxy, such as OCH₃, OC₂H₅, n-propoxyx or             isopropoxy, or C₃-C₄-alkenyloxy, such as allyloxy, with R¹²²             in particular being OCH₃, OC₂H₅ or n-propoxy;         -   R¹²³ is OH, C₁-C₄-alkoxy, such as OCH₃ or OC₂H₅, or             C₃-C₄-alkenyloxy, such as allyloxy, with R¹²³ in particular             being OCH₃ or OC₂H₅;         -   R¹²⁴ is C₁-C₄-alkyl, such as CH₃ or C₂H₅, or             C₁-C₄-alkoxy-C₁-C₄-alkyl, such as methoxymethyl,             ethoxymethyl, 2-methoxyethyl or 2-ethoxyethyl, with R¹²⁴ in             particular being methyl.

Particular examples of radicals R¹² are the following radicals A¹¹-1, A¹¹-1a, A¹¹-1b, A¹¹-2, A¹¹-2a, A¹¹-2b, A¹¹-3, A¹¹-3a and A¹¹-3b:

In another preferred embodiment compounds of formula I, R¹² is A¹¹, preferably A¹¹-1;

In another preferred embodiment compounds of formula I are selected from compounds of formula I.A to I.F;

-   -   wherein, Ar is phenyl or 5- or 6-membered hetaryl ring which is         substituted with R^(Ar);     -   R^(Ar) is halogen, OH, CN, NO₂, SCN, C₁-C₆-alkyl, C₁-C₆-alkoxy,         or S—R^(e), wherein the alkyl and alkoxy are unsubstituted or         substituted with halogen;     -   B¹ is CR^(B1);     -   B² is CR^(B2);     -   B³ is CR^(B3);     -   R^(B1), R^(B2), and R^(B3) independently of each other are H,         halogen, or C₁-C₆-alkyl;     -   Q is —C(R⁴R⁵)—O—, —N(R²)—S(═O)_(m)—, —N(R²)—C(R⁹R¹⁰)—,         —N(R²)—C(═O)—, —N(R²)—C(═S)—, —N═C(X)—, —N(R²)—C(═NR)—; wherein         Ar is bound to either side of Q;     -   X is N(R³)₂;     -   and R¹ is Y—Z-T-R¹¹ or Y—Z-T-R¹², as defined in formula I.

also In a more preferred embodiment compounds of formula I are compounds of formula I.A or I.F, wherein Ar is phenyl or 5- or 6-membered hetaryl ring which is substituted with R^(Ar);

-   -   R^(Ar) is halogen, OH, CN, NO₂, SCN, C₁-C₆-alkyl, C₁-C₆-alkoxy,         or S—R^(e), wherein the alkyl and alkoxy are unsubstituted or         substituted with halogen;     -   B¹ is CR^(B1);     -   B² is CR^(B2);     -   B³ is CR^(B3);     -   R^(B1), R^(B2), and R^(B3) independently of each other are H,         halogen, or C₁-C₆-alkyl;     -   Ar is Ar¹, Ar², Ar³, Ar⁴, Ar¹⁰, Ar¹⁷, or Ar¹⁸;     -   Q is —C(R⁴R⁵)—O—, —N(R²)—C(R⁹R¹⁰)—, or —N(R²)—C(═O)—; wherein Ar         is bound to either side of Q;     -   R¹ are formulas YZT-1, YZT-5, YZT-6, or YZT-8;

In another preferred embodiment of compounds of formula I, wherein

-   A¹ is N or CR^(A1); -   A² is N or CR^(A2); -   A³ is N or CR^(A3);     -   wherein at least one of the A¹, A², A³ is N; -   B¹ is CR^(B1), B² is CR^(B2), B³ is CR^(B3);     -   R^(B1), R^(B2), R^(B3) independently of each other are H,         halogen, or C₁-C₆-alkyl; -   Q is —C(R⁴R⁵)—O—, —N(R²)—C(R⁹R¹⁰)—, or —N(R²)—C(═O)—; wherein Ar is     bound to either side of Q; -   Ar is Ar¹, Ar², Ar³, Ar⁴, Ar¹⁰, Ar¹⁷, or Ar¹⁸; -   R¹ are formulas Y-1A, Y-5A, Y-6A, or Y-8A, wherein D is R¹¹ or R¹²; -   R¹¹ is selected from R¹¹-1 to R¹¹-29 -   R¹² is A¹¹; preferably A¹¹-1;

In another preferred embodiment of compounds of formula I, wherein

-   A¹ is N, A² is CR^(A2), and A³ is N; or A¹ is CR^(A1), A² is N, and     A³ is N; or A¹ is CR^(A1), A² is CR^(A2), and A³ is N; -   B¹ is CR^(B1), B² is CR^(B2), B³ is CR^(B3);     -   R^(B1),R^(B2), R⁶³ are H; -   Ar is Ar²; -   Q is —N(R²)—C(R⁹R¹⁰)—, wherein C is bound to Ar; or -   Q is —N(R²)—C(═O)—, wherein N is bound to Ar; or -   Q is —C(R⁴R⁵)—O—, wherein C is bound to Ar; -   R¹ are formulas Y-1A, Y-5A, Y-6A, or Y-8A, wherein D is R¹¹ or R¹²; -   R¹¹ is R¹¹-1 or R¹¹-29; -   R¹² is A¹¹-1;     -   more preferred compounds of formula I are selected from         compounds of formula I.1 A to I.6C as shown below, wherein R¹ is         selected from Y-1 A, Y-1B, Y-2A, Y-2B, Y-3A, Y-3B, Y-3C, Y-3D,         Y-4A, Y-4B, Y-4C, Y-4D, Y-5A, Y-5B, Y-6A, Y-6B, Y-7A, Y-7B,         Y-8A, and Y-8B; wherein D is R¹¹ or R¹², and other variables are         as defined herein.

Also more preferred compound of formula I are formulae I.1 to 1.6, wherein

-   -   B¹ is CR^(B1), B² is CR^(B2), B³ is CR^(B3),     -   R^(B1), R^(B2), and R^(B3) independently of each other are H,         halogen, C₁-C₆-alkyl;     -   Q is —C(R⁴R⁵)—O—, —N(R²)—C(R⁹R¹⁰)—, —N(R²)—C(═O)—,         —N(R²)—C(═NR)—; wherein Ar is bound to either side of Q;     -   m is 0, 1, or 2;     -   R is H, CN, or C₁-C₆-alkyl;     -   R² is H or C₁-C₆-alkyl;     -   R⁴, R⁵, R⁹, R¹⁰, are identical or different H or C₁-C₆-alkyl;     -   R⁶ is H, C₁-C₆-alkyl, C₁-C₆-haloalkyl, or —CH₂-phenyl;     -   Ar is Ar¹, Ar², Ar³, Ar⁴, Ar¹⁰, Ar¹⁷, or Ar¹⁸;     -   R¹ is Y-1 A, Y-3C, Y-5A, Y-6A, Y-7A, Y-8A, or Y-9A;     -   D is R¹¹ or R¹²;     -   R¹¹ is R¹¹-1 or R¹¹-10;     -   R¹² is A¹¹-1b or A¹¹-3b;

In another preferred embodiment, the compound of formula I are selected from compounds of formula I.1 to I.48, wherein the variables are as defined in the compound of formula I;

In another preferred embodiment, the compound of formula I are selected from compounds of formula I.1 to I.48, wherein

-   -   Ar is Ar¹, Ar², Ar³, Ar⁴, Ar¹⁰, Ar¹⁷, or Ar¹⁸;     -   B¹ is CH;     -   B² is CH;     -   B³ is CH;     -   R¹ is Y-1 A, Y-1B, Y-2A, Y-2B, Y-3A, Y-3B, Y-3C, Y-3D, Y-4A,         Y-4B, Y-4C, Y-4D, Y-5A, Y-5B, Y-6A, Y-6B, Y-7A, Y-7B, Y-8A, or         Y-8B; wherein D is R¹¹ or R¹²;     -   R¹¹ is R¹¹-1, R¹¹-2, R¹¹-3, R¹¹-4, R¹¹-5, R¹¹-6, R¹¹-7, R¹¹-8,         R¹¹-9, R¹¹-10, R¹¹-11, R¹¹-12, R¹¹-13, R¹¹-14, R¹¹-15, R¹¹-16,         R¹¹-17, R¹¹-18, R¹¹-19, R¹¹-20, R¹¹-21, R¹¹-22, R¹¹-23, R¹¹-24,         R¹¹-25, R¹¹-26, R¹¹-27, R¹¹-28, or R¹¹-29;     -   R¹² is (A¹¹-1), (A¹¹-2), or (A¹¹-3).     -   R⁴ and R⁵ independently are H or CH₃,     -   R⁹ and R¹⁰ independently are H or CH₃,     -   R² is H, CH₃, or c-C₃H₅     -   R is NH, NCH₃, or NCN;

Particular compounds of formula I are the compounds of the formulae I.1 to I.24 that are compiled in the following tables 1 to 2160, wherein the term Formula denotes compounds of formula, and wherein combination of variables B¹, B², B³, Ar, and D for each compound of tables 1 to 2160 corresponds to each line of Table B. Each of the groups mentioned fora substituent in the tables is furthermore per se, independently of the combination in which it is mentioned, a particularly preferred aspect of the substituent in question.

Table 1. Formula I.1 wherein R¹ is Y-1 A, R⁴ is H and R⁵ is H. Table 2. Formula I.1 wherein R¹ is Y-1B, R⁴ is H and R⁵ is H. Table 3. Formula I.1 wherein R¹ is Y-2A, R⁴ is H and R⁵ is H. Table 4. Formula I.1 wherein R¹ is Y-2B, R⁴ is H and R⁵ is H. Table 5. Formula I.1 wherein R¹ is Y-3A, R⁴ is H and R⁵ is H. Table 6. Formula I.1 wherein R¹ is Y-3B, R⁴ is H and R⁵ is H. Table 7. Formula I.1 wherein R¹ is Y-3C, R⁴ is H and R⁵ is H. Table 8. Formula I.1 wherein R¹ is Y-3D, R⁴ is H and R⁵ is H. Table 9. Formula I.1 wherein R¹ is Y-4A, R⁴ is H and R⁵ is H. Table 10. Formula I.1 wherein R¹ is Y-4B, R⁴ is H and R⁵ is H. Table 11. Formula I.1 wherein R¹ is Y-4C, R⁴ is H and R⁵ is H. Table 12. Formula I.1 wherein R¹ is Y-4D, R⁴ is H and R⁵ is H. Table 13. Formula I.1 wherein R¹ is Y-5A, R⁴ is H and R⁵ is H. Table 14. Formula I.1 wherein R¹ is Y-5B, R⁴ is H and R⁵ is H. Table 15. Formula I.1 wherein R¹ is Y-6A, R⁴ is H and R⁵ is H. Table 16. Formula I.1 wherein R¹ is Y-6B, R⁴ is H and R⁵ is H. Table 17. Formula I.1 wherein R¹ is Y-7A, R⁴ is H and R⁵ is H. Table 18. Formula I.1 wherein R¹ is Y-7B, R⁴ is H and R⁵ is H. Table 19. Formula I.1 wherein R¹ is Y-8A, R⁴ is H and R⁵ is H. Table 20. Formula I.1 wherein R¹ is Y-8B, R⁴ is H and R⁵ is H. Table 21. Formula I.1 wherein R¹ is Y-1 A, R⁴ is CH₃ and R⁵ is H. Table 22. Formula I.1 wherein R¹ is Y-1B, R⁴ is CH₃ and R⁵ is H. Table 23. Formula I.1 wherein R¹ is Y-2A, R⁴ is CH₃ and R⁵ is H. Table 24. Formula I.1 wherein R¹ is Y-2B, R⁴ is CH₃ and R⁵ is H. Table 25. Formula I.1 wherein R¹ is Y-3A, R⁴ is CH₃ and R⁵ is H. Table 26. Formula I.1 wherein R¹ is Y-3B, R⁴ is CH₃ and R⁵ is H. Table 27. Formula I.1 wherein R¹ is Y-3C, R⁴ is CH₃ and R⁵ is H. Table 28. Formula I.1 wherein R¹ is Y-3D, R⁴ is CH₃ and R⁵ is H. Table 29. Formula I.1 wherein R¹ is Y-4A, R⁴ is CH₃ and R⁵ is H. Table 30. Formula I.1 wherein R¹ is Y-4B, R⁴ is CH₃ and R⁵ is H. Table 31. Formula I.1 wherein R¹ is Y-4C, R⁴ is CH₃ and R⁵ is H. Table 32. Formula I.1 wherein R¹ is Y-4D, R⁴ is CH₃ and R⁵ is H. Table 33. Formula I.1 wherein R¹ is Y-5A, R⁴ is CH₃ and R⁵ is H. Table 34. Formula I.1 wherein R¹ is Y-5B, R⁴ is CH₃ and R⁵ is H. Table 35. Formula I.1 wherein R¹ is Y-6A, R⁴ is CH₃ and R⁵ is H. Table 36. Formula I.1 wherein R¹ is Y-6B, R⁴ is CH₃ and R⁵ is H. Table 37. Formula I.1 wherein R¹ is Y-7A, R⁴ is CH₃ and R⁵ is H. Table 38. Formula I.1 wherein R¹ is Y-7B, R⁴ is CH₃ and R⁵ is H. Table 39. Formula I.1 wherein R¹ is Y-8A, R⁴ is CH₃ and R⁵ is H. Table 40. Formula I.1 wherein R¹ is Y-8B, R⁴ is CH₃ and R⁵ is H. Table 41. Formula I.1 wherein R¹ is Y-1 A, R⁴ is CH₃ and R⁵ is CH₃. Table 42. Formula I.1 wherein R¹ is Y-1B, R⁴ is CH₃ and R⁵ is CH₃. Table 43. Formula I.1 wherein R¹ is Y-2A, R⁴ is CH₃ and R⁵ is CH₃. Table 44. Formula I.1 wherein R¹ is Y-2B, R⁴ is CH₃ and R⁵ is CH₃. Table 45. Formula I.1 wherein R¹ is Y-3A, R⁴ is CH₃ and R⁵ is CH₃. Table 46. Formula I.1 wherein R¹ is Y-3B, R⁴ is CH₃ and R⁵ is CH₃. Table 47. Formula I.1 wherein R¹ is Y-3C, R⁴ is CH₃ and R⁵ is CH₃. Table 48. Formula I.1 wherein R¹ is Y-3D, R⁴ is CH₃ and R⁵ is CH₃. Table 49. Formula I.1 wherein R¹ is Y-4A, R⁴ is CH₃ and R⁵ is CH₃. Table 50. Formula I.1 wherein R¹ is Y-4B, R⁴ is CH₃ and R⁵ is CH₃. Table 51. Formula I.1 wherein R¹ is Y-4C, R⁴ is CH₃ and R⁵ is CH₃. Table 52. Formula I.1 wherein R¹ is Y-4D, R⁴ is CH₃ and R⁵ is CH₃. Table 53. Formula I.1 wherein R¹ is Y-5A, R⁴ is CH₃ and R⁵ is CH₃. Table 54. Formula I.1 wherein R¹ is Y-5B, R⁴ is CH₃ and R⁵ is CH₃. Table 55. Formula I.1 wherein R¹ is Y-6A, R⁴ is CH₃ and R⁵ is CH₃. Table 56. Formula I.1 wherein R¹ is Y-6B, R⁴ is CH₃ and R⁵ is CH₃. Table 57. Formula I.1 wherein R¹ is Y-7A, R⁴ is CH₃ and R⁵ is CH₃. Table 58. Formula I.1 wherein R¹ is Y-7B, R⁴ is CH₃ and R⁵ is CH₃. Table 59. Formula I.1 wherein R¹ is Y-8A, R⁴ is CH₃ and R⁵ is CH₃. Table 60. Formula I.1 wherein R¹ is Y-8B, R⁴ is CH₃ and R⁵ is CH₃. Table 61. Formula I.2 wherein R¹ is Y-1 A, R⁴ is H and R⁵ is H. Table 62. Formula I.2 wherein R¹ is Y-1B, R⁴ is H and R⁵ is H. Table 63. Formula I.2 wherein R¹ is Y-2A, R⁴ is H and R⁵ is H. Table 64. Formula I.2 wherein R¹ is Y-2B, R⁴ is H and R⁵ is H. Table 65. Formula I.2 wherein R¹ is Y-3A, R⁴ is H and R⁵ is H. Table 66. Formula I.2 wherein R¹ is Y-3B, R⁴ is H and R⁵ is H. Table 67. Formula I.2 wherein R¹ is Y-3C, R⁴ is H and R⁵ is H. Table 68. Formula I.2 wherein R¹ is Y-3D, R⁴ is H and R⁵ is H. Table 69. Formula I.2 wherein R¹ is Y-4A, R⁴ is H and R⁵ is H. Table 70. Formula I.2 wherein R¹ is Y-4B, R⁴ is H and R⁵ is H. Table 71. Formula I.2 wherein R¹ is Y-4C, R⁴ is H and R⁵ is H. Table 72. Formula I.2 wherein R¹ is Y-4D, R⁴ is H and R⁵ is H. Table 73. Formula I.2 wherein R¹ is Y-5A, R⁴ is H and R⁵ is H. Table 74. Formula I.2 wherein R¹ is Y-5B, R⁴ is H and R⁵ is H. Table 75. Formula I.2 wherein R¹ is Y-6A, R⁴ is H and R⁵ is H. Table 76. Formula I.2 wherein R¹ is Y-6B, R⁴ is H and R⁵ is H. Table 77. Formula I.2 wherein R¹ is Y-7A, R⁴ is H and R⁵ is H. Table 78. Formula I.2 wherein R¹ is Y-7B, R⁴ is H and R⁵ is H. Table 79. Formula I.2 wherein R¹ is Y-8A, R⁴ is H and R⁵ is H. Table 80. Formula I.2 wherein R¹ is Y-8B, R⁴ is H and R⁵ is H. Table 81. Formula I.2 wherein R¹ is Y-1 A, R⁴ is CH₃ and R⁵ is H. Table 82. Formula I.2 wherein R¹ is Y-1B, R⁴ is CH₃ and R⁵ is H. Table 83. Formula I.2 wherein R¹ is Y-2A, R⁴ is CH₃ and R⁵ is H. Table 84. Formula I.2 wherein R¹ is Y-2B, R⁴ is CH₃ and R⁵ is H. Table 85. Formula I.2 wherein R¹ is Y-3A, R⁴ is CH₃ and R⁵ is H. Table 86. Formula I.2 wherein R¹ is Y-3B, R⁴ is CH₃ and R⁵ is H. Table 87. Formula I.2 wherein R¹ is Y-3C, R⁴ is CH₃ and R⁵ is H. Table 88. Formula I.2 wherein R¹ is Y-3D, R⁴ is CH₃ and R⁵ is H. Table 89. Formula I.2 wherein R¹ is Y-4A, R⁴ is CH₃ and R⁵ is H. Table 90. Formula I.2 wherein R¹ is Y-4B, R⁴ is CH₃ and R⁵ is H. Table 91. Formula I.2 wherein R¹ is Y-4C, R⁴ is CH₃ and R⁵ is H. Table 92. Formula I.2 wherein R¹ is Y-4D, R⁴ is CH₃ and R⁵ is H. Table 93. Formula I.2 wherein R¹ is Y-5A, R⁴ is CH₃ and R⁵ is H. Table 94. Formula I.2 wherein R¹ is Y-5B, R⁴ is CH₃ and R⁵ is H. Table 95. Formula I.2 wherein R¹ is Y-6A, R⁴ is CH₃ and R⁵ is H. Table 96. Formula I.2 wherein R¹ is Y-6B, R⁴ is CH₃ and R⁵ is H. Table 97. Formula I.2 wherein R¹ is Y-7A, R⁴ is CH₃ and R⁵ is H. Table 98. Formula I.2 wherein R¹ is Y-7B, R⁴ is CH₃ and R⁵ is H. Table 99. Formula I.2 wherein R¹ is Y-8A, R⁴ is CH₃ and R⁵ is H. Table 100. Formula I.2 wherein R¹ is Y-8B, R⁴ is CH₃ and R⁵ is H. Table 101. Formula I.2 wherein R¹ is Y-1 A, R⁴ is CH₃ and R⁵ is CH₃. Table 102. Formula I.2 wherein R¹ is Y-1B, R⁴ is CH₃ and R⁵ is CH₃. Table 103. Formula I.2 wherein R¹ is Y-2A, R⁴ is CH₃ and R⁵ is CH₃. Table 104. Formula I.2 wherein R¹ is Y-2B, R⁴ is CH₃ and R⁵ is CH₃. Table 105. Formula I.2 wherein R¹ is Y-3A, R⁴ is CH₃ and R⁵ is CH₃. Table 106. Formula I.2 wherein R¹ is Y-3B, R⁴ is CH₃ and R⁵ is CH₃. Table 107. Formula I.2 wherein R¹ is Y-3C, R⁴ is CH₃ and R⁵ is CH₃. Table 108. Formula I.2 wherein R¹ is Y-3D, R⁴ is CH₃ and R⁵ is CH₃. Table 109. Formula I.2 wherein R¹ is Y-4A, R⁴ is CH₃ and R⁵ is CH₃. Table 110. Formula I.2 wherein R¹ is Y-4B, R⁴ is CH₃ and R⁵ is CH₃. Table 111. Formula I.2 wherein R¹ is Y-4C, R⁴ is CH₃ and R⁵ is CH₃. Table 112. Formula I.2 wherein R¹ is Y-4D, R⁴ is CH₃ and R⁵ is CH₃. Table 113. Formula I.2 wherein R¹ is Y-5A, R⁴ is CH₃ and R⁵ is CH₃. Table 114. Formula I.2 wherein R¹ is Y-5B, R⁴ is CH₃ and R⁵ is CH₃. Table 115. Formula I.2 wherein R¹ is Y-6A, R⁴ is CH₃ and R⁵ is CH₃. Table 116. Formula I.2 wherein R¹ is Y-6B, R⁴ is CH₃ and R⁵ is CH₃. Table 117. Formula I.2 wherein R¹ is Y-7A, R⁴ is CH₃ and R⁵ is CH₃. Table 118. Formula I.2 wherein R¹ is Y-7B, R⁴ is CH₃ and R⁵ is CH₃. Table 119. Formula I.2 wherein R¹ is Y-8A, R⁴ is CH₃ and R⁵ is CH₃. Table 120. Formula I.2 wherein R¹ is Y-8B, R⁴ is CH₃ and R⁵ is CH₃. Table 121. Formula I.5 wherein R¹ is Y-1A, R⁴ is H and R⁵ is H. Table 122. Formula I.5 wherein R¹ is Y-1B, R⁴ is H and R⁵ is H. Table 123. Formula I.5 wherein R¹ is Y-2A, R⁴ is H and R⁵ is H. Table 124. Formula I.5 wherein R¹ is Y-2B, R⁴ is H and R⁵ is H. Table 125. Formula I.5 wherein R¹ is Y-3A, R⁴ is H and R⁵ is H. Table 126. Formula I.5 wherein R¹ is Y-3B, R⁴ is H and R⁵ is H. Table 127. Formula I.5 wherein R¹ is Y-3C, R⁴ is H and R⁵ is H. Table 128. Formula I.5 wherein R¹ is Y-3D, R⁴ is H and R⁵ is H. Table 129. Formula I.5 wherein R¹ is Y-4A, R⁴ is H and R⁵ is H. Table 130. Formula I.5 wherein R¹ is Y-4B, R⁴ is H and R⁵ is H. Table 131. Formula I.5 wherein R¹ is Y-4C, R⁴ is H and R⁵ is H. Table 132. Formula I.5 wherein R¹ is Y-4D, R⁴ is H and R⁵ is H. Table 133. Formula I.5 wherein R¹ is Y-5A, R⁴ is H and R⁵ is H. Table 134. Formula I.5 wherein R¹ is Y-5B, R⁴ is H and R⁵ is H. Table 135. Formula I.5 wherein R¹ is Y-6A, R⁴ is H and R⁵ is H. Table 136. Formula I.5 wherein R¹ is Y-6B, R⁴ is H and R⁵ is H. Table 137. Formula I.5 wherein R¹ is Y-7A, R⁴ is H and R⁵ is H. Table 138. Formula I.5 wherein R¹ is Y-7B, R⁴ is H and R⁵ is H. Table 139. Formula I.5 wherein R¹ is Y-8A, R⁴ is H and R⁵ is H. Table 140. Formula I.5 wherein R¹ is Y-8B, R⁴ is H and R⁵ is H. Table 141. Formula I.5 wherein R¹ is Y-1 A, R⁴ is CH₃ and R⁵ is H. Table 142. Formula I.5 wherein R¹ is Y-1B, R⁴ is CH₃ and R⁵ is H. Table 143. Formula I.5 wherein R¹ is Y-2A, R⁴ is CH₃ and R⁵ is H. Table 144. Formula I.5 wherein R¹ is Y-2B, R⁴ is CH₃ and R⁵ is H. Table 145. Formula I.5 wherein R¹ is Y-3A, R⁴ is CH₃ and R⁵ is H. Table 146. Formula I.5 wherein R¹ is Y-3B, R⁴ is CH₃ and R⁵ is H. Table 147. Formula I.5 wherein R¹ is Y-3C, R⁴ is CH₃ and R⁵ is H. Table 148. Formula I.5 wherein R¹ is Y-3D, R⁴ is CH₃ and R⁵ is H. Table 149. Formula I.5 wherein R¹ is Y-4A, R⁴ is CH₃ and R⁵ is H. Table 150. Formula I.5 wherein R¹ is Y-4B, R⁴ is CH₃ and R⁵ is H. Table 151. Formula I.5 wherein R¹ is Y-4C, R⁴ is CH₃ and R⁵ is H. Table 152. Formula I.5 wherein R¹ is Y-4D, R⁴ is CH₃ and R⁵ is H. Table 153. Formula I.5 wherein R¹ is Y-5A, R⁴ is CH₃ and R⁵ is H. Table 154. Formula I.5 wherein R¹ is Y-5B, R⁴ is CH₃ and R⁵ is H. Table 155. Formula I.5 wherein R¹ is Y-6A, R⁴ is CH₃ and R⁵ is H. Table 156. Formula I.5 wherein R¹ is Y-6B, R⁴ is CH₃ and R⁵ is H. Table 157. Formula I.5 wherein R¹ is Y-7A, R⁴ is CH₃ and R⁵ is H. Table 158. Formula I.5 wherein R¹ is Y-7B, R⁴ is CH₃ and R⁵ is H. Table 159. Formula I.5 wherein R¹ is Y-8A, R⁴ is CH₃ and R⁵ is H. Table 160. Formula I.5 wherein R¹ is Y-8B, R⁴ is CH₃ and R⁵ is H. Table 161. Formula I.5 wherein R¹ is Y-1 A, R⁴ is CH₃ and R⁵ is CH₃. Table 162. Formula I.5 wherein R¹ is Y-1B, R⁴ is CH₃ and R⁵ is CH₃. Table 163. Formula I.5 wherein R¹ is Y-2A, R⁴ is CH₃ and R⁵ is CH₃. Table 164. Formula I.5 wherein R¹ is Y-2B, R⁴ is CH₃ and R⁵ is CH₃. Table 165. Formula I.5 wherein R¹ is Y-3A, R⁴ is CH₃ and R⁵ is CH₃. Table 166. Formula I.5 wherein R¹ is Y-3B, R⁴ is CH₃ and R⁵ is CH₃. Table 167. Formula I.5 wherein R¹ is Y-3C, R⁴ is CH₃ and R⁵ is CH₃. Table 168. Formula I.5 wherein R¹ is Y-3D, R⁴ is CH₃ and R⁵ is CH₃. Table 169. Formula I.5 wherein R¹ is Y-4A, R⁴ is CH₃ and R⁵ is CH₃. Table 170. Formula I.5 wherein R¹ is Y-4B, R⁴ is CH₃ and R⁵ is CH₃. Table 171. Formula I.5 wherein R¹ is Y-4C, R⁴ is CH₃ and R⁵ is CH₃. Table 172. Formula I.5 wherein R¹ is Y-4D, R⁴ is CH₃ and R⁵ is CH₃. Table 173. Formula I.5 wherein R¹ is Y-5A, R⁴ is CH₃ and R⁵ is CH₃. Table 174. Formula I.5 wherein R¹ is Y-5B, R⁴ is CH₃ and R⁵ is CH₃. Table 175. Formula I.5 wherein R¹ is Y-6A, R⁴ is CH₃ and R⁵ is CH₃. Table 176. Formula I.5 wherein R¹ is Y-6B, R⁴ is CH₃ and R⁵ is CH₃. Table 177. Formula I.5 wherein R¹ is Y-7A, R⁴ is CH₃ and R⁵ is CH₃. Table 178. Formula I.5 wherein R¹ is Y-7B, R⁴ is CH₃ and R⁵ is CH₃. Table 179. Formula I.5 wherein R¹ is Y-8A, R⁴ is CH₃ and R⁵ is CH₃. Table 180. Formula I.5 wherein R¹ is Y-8B, R⁴ is CH₃ and R⁵ is CH₃. Table 181. Formula I.6 wherein R¹ is Y-1 A, R⁴ is H and R⁵ is H. Table 182. Formula I.6 wherein R¹ is Y-1B, R⁴ is H and R⁵ is H. Table 183. Formula I.6 wherein R¹ is Y-2A, R⁴ is H and R⁵ is H. Table 184. Formula I.6 wherein R¹ is Y-2B, R⁴ is H and R⁵ is H. Table 185. Formula I.6 wherein R¹ is Y-3A, R⁴ is H and R⁵ is H. Table 186. Formula I.6 wherein R¹ is Y-3B, R⁴ is H and R⁵ is H. Table 187. Formula I.6 wherein R¹ is Y-3C, R⁴ is H and R⁵ is H. Table 188. Formula I.6 wherein R¹ is Y-3D, R⁴ is H and R⁵ is H. Table 189. Formula I.6 wherein R¹ is Y-4A, R⁴ is H and R⁵ is H. Table 190. Formula I.6 wherein R¹ is Y-4B, R⁴ is H and R⁵ is H. Table 191. Formula I.6 wherein R¹ is Y-4C, R⁴ is H and R⁵ is H. Table 192. Formula I.6 wherein R¹ is Y-4D, R⁴ is H and R⁵ is H. Table 193. Formula I.6 wherein R¹ is Y-5A, R⁴ is H and R⁵ is H. Table 194. Formula I.6 wherein R¹ is Y-5B, R⁴ is H and R⁵ is H. Table 195. Formula I.6 wherein R¹ is Y-6A, R⁴ is H and R⁵ is H. Table 196. Formula I.6 wherein R¹ is Y-6B, R⁴ is H and R⁵ is H. Table 197. Formula I.6 wherein R¹ is Y-7A, R⁴ is H and R⁵ is H. Table 198. Formula I.6 wherein R¹ is Y-7B, R⁴ is H and R⁵ is H. Table 199. Formula I.6 wherein R¹ is Y-8A, R⁴ is H and R⁵ is H. Table 200. Formula I.6 wherein R¹ is Y-8B, R⁴ is H and R⁵ is H. Table 201. Formula I.6 wherein R¹ is Y-1 A, R⁴ is CH₃ and R⁵ is H. Table 202. Formula I.6 wherein R¹ is Y-1B, R⁴ is CH₃ and R⁵ is H. Table 203. Formula I.6 wherein R¹ is Y-2A, R⁴ is CH₃ and R⁵ is H. Table 204. Formula I.6 wherein R¹ is Y-2B, R⁴ is CH₃ and R⁵ is H. Table 205. Formula I.6 wherein R¹ is Y-3A, R⁴ is CH₃ and R⁵ is H. Table 206. Formula I.6 wherein R¹ is Y-3B, R⁴ is CH₃ and R⁵ is H. Table 207. Formula I.6 wherein R¹ is Y-3C, R⁴ is CH₃ and R⁵ is H. Table 208. Formula I.6 wherein R¹ is Y-3D, R⁴ is CH₃ and R⁵ is H. Table 209. Formula I.6 wherein R¹ is Y-4A, R⁴ is CH₃ and R⁵ is H. Table 210. Formula I.6 wherein R¹ is Y-4B, R⁴ is CH₃ and R⁵ is H. Table 211. Formula I.6 wherein R¹ is Y-4C, R⁴ is CH₃ and R⁵ is H. Table 212. Formula I.6 wherein R¹ is Y-4D, R⁴ is CH₃ and R⁵ is H. Table 213. Formula I.6 wherein R¹ is Y-5A, R⁴ is CH₃ and R⁵ is H. Table 214. Formula I.6 wherein R¹ is Y-5B, R⁴ is CH₃ and R⁵ is H. Table 215. Formula I.6 wherein R¹ is Y-6A, R⁴ is CH₃ and R⁵ is H. Table 216. Formula I.6 wherein R¹ is Y-6B, R⁴ is CH₃ and R⁵ is H. Table 217. Formula I.6 wherein R¹ is Y-7A, R⁴ is CH₃ and R⁵ is H. Table 218. Formula I.6 wherein R¹ is Y-7B, R⁴ is CH₃ and R⁵ is H. Table 219. Formula I.6 wherein R¹ is Y-8A, R⁴ is CH₃ and R⁵ is H. Table 220. Formula I.6 wherein R¹ is Y-8B, R⁴ is CH₃ and R⁵ is H. Table 221. Formula I.6 wherein R¹ is Y-1 A, R⁴ is CH₃ and R⁵ is CH₃. Table 222. Formula I.6 wherein R¹ is Y-1B, R⁴ is CH₃ and R⁵ is CH₃. Table 223. Formula I.6 wherein R¹ is Y-2A, R⁴ is CH₃ and R⁵ is CH₃. Table 224. Formula I.6 wherein R¹ is Y-2B, R⁴ is CH₃ and R⁵ is CH₃. Table 225. Formula I.6 wherein R¹ is Y-3A, R⁴ is CH₃ and R⁵ is CH₃. Table 226. Formula I.6 wherein R¹ is Y-3B, R⁴ is CH₃ and R⁵ is CH₃. Table 227. Formula I.6 wherein R¹ is Y-3C, R⁴ is CH₃ and R⁵ is CH₃. Table 228. Formula I.6 wherein R¹ is Y-3D, R⁴ is CH₃ and R⁵ is CH₃. Table 229. Formula I.6 wherein R¹ is Y-4A, R⁴ is CH₃ and R⁵ is CH₃. Table 230. Formula I.6 wherein R¹ is Y-4B, R⁴ is CH₃ and R⁵ is CH₃. Table 231. Formula I.6 wherein R¹ is Y-4C, R⁴ is CH₃ and R⁵ is CH₃. Table 232. Formula I.6 wherein R¹ is Y-4D, R⁴ is CH₃ and R⁵ is CH₃. Table 233. Formula I.6 wherein R¹ is Y-5A, R⁴ is CH₃ and R⁵ is CH₃. Table 234. Formula I.6 wherein R¹ is Y-5B, R⁴ is CH₃ and R⁵ is CH₃. Table 235. Formula I.6 wherein R¹ is Y-6A, R⁴ is CH₃ and R⁵ is CH₃. Table 236. Formula I.6 wherein R¹ is Y-6B, R⁴ is CH₃ and R⁵ is CH₃. Table 237. Formula I.6 wherein R¹ is Y-7A, R⁴ is CH₃ and R⁵ is CH₃. Table 238. Formula I.6 wherein R¹ is Y-7B, R⁴ is CH₃ and R⁵ is CH₃. Table 239. Formula I.6 wherein R¹ is Y-8A, R⁴ is CH₃ and R⁵ is CH₃. Table 240. Formula I.6 wherein R¹ is Y-8B, R⁴ is CH₃ and R⁵ is CH₃. Table 241. Formula I.7 wherein R¹ is Y-1 A, R⁴ is H and R⁵ is H. Table 242. Formula I.7 wherein R¹ is Y-1B, R⁴ is H and R⁵ is H. Table 243. Formula I.7 wherein R¹ is Y-2A, R⁴ is H and R⁵ is H. Table 244. Formula I.7 wherein R¹ is Y-2B, R⁴ is H and R⁵ is H. Table 245. Formula I.7 wherein R¹ is Y-3A, R⁴ is H and R⁵ is H. Table 246. Formula I.7 wherein R¹ is Y-3B, R⁴ is H and R⁵ is H. Table 247. Formula I.7 wherein R¹ is Y-3C, R⁴ is H and R⁵ is H. Table 248. Formula I.7 wherein R¹ is Y-3D, R⁴ is H and R⁵ is H. Table 249. Formula I.7 wherein R¹ is Y-4A, R⁴ is H and R⁵ is H. Table 250. Formula I.7 wherein R¹ is Y-4B, R⁴ is H and R⁵ is H. Table 251. Formula I.7 wherein R¹ is Y-4C, R⁴ is H and R⁵ is H. Table 252. Formula I.7 wherein R¹ is Y-4D, R⁴ is H and R⁵ is H. Table 253. Formula I.7 wherein R¹ is Y-5A, R⁴ is H and R⁵ is H. Table 254. Formula I.7 wherein R¹ is Y-5B, R⁴ is H and R⁵ is H. Table 255. Formula I.7 wherein R¹ is Y-6A, R⁴ is H and R⁵ is H. Table 256. Formula I.7 wherein R¹ is Y-6B, R⁴ is H and R⁵ is H. Table 257. Formula I.7 wherein R¹ is Y-7A, R⁴ is H and R⁵ is H. Table 258. Formula I.7 wherein R¹ is Y-7B, R⁴ is H and R⁵ is H. Table 259. Formula I.7 wherein R¹ is Y-8A, R⁴ is H and R⁵ is H. Table 260. Formula I.7 wherein R¹ is Y-8B, R⁴ is H and R⁵ is H. Table 261. Formula I.7 wherein R¹ is Y-1 A, R⁴ is CH₃ and R⁵ is H. Table 262. Formula I.7 wherein R¹ is Y-1B, R⁴ is CH₃ and R⁵ is H. Table 263. Formula I.7 wherein R¹ is Y-2A, R⁴ is CH₃ and R⁵ is H. Table 264. Formula I.7 wherein R¹ is Y-2B, R⁴ is CH₃ and R⁵ is H. Table 265. Formula I.7 wherein R¹ is Y-3A, R⁴ is CH₃ and R⁵ is H. Table 266. Formula I.7 wherein R¹ is Y-3B, R⁴ is CH₃ and R⁵ is H. Table 267. Formula I.7 wherein R¹ is Y-3C, R⁴ is CH₃ and R⁵ is H. Table 268. Formula I.7 wherein R¹ is Y-3D, R⁴ is CH₃ and R⁵ is H. Table 269. Formula I.7 wherein R¹ is Y-4A, R⁴ is CH₃ and R⁵ is H. Table 270. Formula I.7 wherein R¹ is Y-4B, R⁴ is CH₃ and R⁵ is H. Table 271. Formula I.7 wherein R¹ is Y-4C, R⁴ is CH₃ and R⁵ is H. Table 272. Formula I.7 wherein R¹ is Y-4D, R⁴ is CH₃ and R⁵ is H. Table 273. Formula I.7 wherein R¹ is Y-5A, R⁴ is CH₃ and R⁵ is H. Table 274. Formula I.7 wherein R¹ is Y-5B, R⁴ is CH₃ and R⁵ is H. Table 275. Formula I.7 wherein R¹ is Y-6A, R⁴ is CH₃ and R⁵ is H. Table 276. Formula I.7 wherein R¹ is Y-6B, R⁴ is CH₃ and R⁵ is H. Table 277. Formula I.7 wherein R¹ is Y-7A, R⁴ is CH₃ and R⁵ is H. Table 278. Formula I.7 wherein R¹ is Y-7B, R⁴ is CH₃ and R⁵ is H. Table 279. Formula I.7 wherein R¹ is Y-8A, R⁴ is CH₃ and R⁵ is H. Table 280. Formula I.7 wherein R¹ is Y-8B, R⁴ is CH₃ and R⁵ is H. Table 281. Formula I.7 wherein R¹ is Y-1 A, R⁴ is CH₃ and R⁵ is CH₃. Table 282. Formula I.7 wherein R¹ is Y-1B, R⁴ is CH₃ and R⁵ is CH₃. Table 283. Formula I.7 wherein R¹ is Y-2A, R⁴ is CH₃ and R⁵ is CH₃. Table 284. Formula I.7 wherein R¹ is Y-2B, R⁴ is CH₃ and R⁵ is CH₃. Table 285. Formula I.7 wherein R¹ is Y-3A, R⁴ is CH₃ and R⁵ is CH₃. Table 286. Formula I.7 wherein R¹ is Y-3B, R⁴ is CH₃ and R⁵ is CH₃. Table 287. Formula I.7 wherein R¹ is Y-3C, R⁴ is CH₃ and R⁵ is CH₃. Table 288. Formula I.7 wherein R¹ is Y-3D, R⁴ is CH₃ and R⁵ is CH₃. Table 289. Formula I.7 wherein R¹ is Y-4A, R⁴ is CH₃ and R⁵ is CH₃. Table 290. Formula I.7 wherein R¹ is Y-4B, R⁴ is CH₃ and R⁵ is CH₃. Table 291. Formula I.7 wherein R¹ is Y-4C, R⁴ is CH₃ and R⁵ is CH₃. Table 292. Formula I.7 wherein R¹ is Y-4D, R⁴ is CH₃ and R⁵ is CH₃. Table 293. Formula I.7 wherein R¹ is Y-5A, R⁴ is CH₃ and R⁵ is CH₃. Table 294. Formula I.7 wherein R¹ is Y-5B, R⁴ is CH₃ and R⁵ is CH₃. Table 295. Formula I.7 wherein R¹ is Y-6A, R⁴ is CH₃ and R⁵ is CH₃. Table 296. Formula I.7 wherein R¹ is Y-6B, R⁴ is CH₃ and R⁵ is CH₃. Table 297. Formula I.7 wherein R¹ is Y-7A, R⁴ is CH₃ and R⁵ is CH₃. Table 298. Formula I.7 wherein R¹ is Y-7B, R⁴ is CH₃ and R⁵ is CH₃. Table 299. Formula I.7 wherein R¹ is Y-8A, R⁴ is CH₃ and R⁵ is CH₃. Table 300. Formula I.7 wherein R¹ is Y-8B, R⁴ is CH₃ and R⁵ is CH₃. Table 301. Formula I.8 wherein R¹ is Y-1 A, R⁴ is H and R⁵ is H. Table 302. Formula I.8 wherein R¹ is Y-1B, R⁴ is H and R⁵ is H. Table 303. Formula I.8 wherein R¹ is Y-2A, R⁴ is H and R⁵ is H. Table 304. Formula I.8 wherein R¹ is Y-2B, R⁴ is H and R⁵ is H. Table 305. Formula I.8 wherein R¹ is Y-3A, R⁴ is H and R⁵ is H. Table 306. Formula I.8 wherein R¹ is Y-3B, R⁴ is H and R⁵ is H. Table 307. Formula I.8 wherein R¹ is Y-3C, R⁴ is H and R⁵ is H. Table 308. Formula I.8 wherein R¹ is Y-3D, R⁴ is H and R⁵ is H. Table 309. Formula I.8 wherein R¹ is Y-4A, R⁴ is H and R⁵ is H. Table 310. Formula I.8 wherein R¹ is Y-4B, R⁴ is H and R⁵ is H. Table 311. Formula I.8 wherein R¹ is Y-4C, R⁴ is H and R⁵ is H. Table 312. Formula I.8 wherein R¹ is Y-4D, R⁴ is H and R⁵ is H. Table 313. Formula I.8 wherein R¹ is Y-5A, R⁴ is H and R⁵ is H. Table 314. Formula I.8 wherein R¹ is Y-5B, R⁴ is H and R⁵ is H. Table 315. Formula I.8 wherein R¹ is Y-6A, R⁴ is H and R⁵ is H. Table 316. Formula I.8 wherein R¹ is Y-6B, R⁴ is H and R⁵ is H. Table 317. Formula I.8 wherein R¹ is Y-7A, R⁴ is H and R⁵ is H. Table 318. Formula I.8 wherein R¹ is Y-7B, R⁴ is H and R⁵ is H. Table 319. Formula I.8 wherein R¹ is Y-8A, R⁴ is H and R⁵ is H. Table 320. Formula I.8 wherein R¹ is Y-8B, R⁴ is H and R⁵ is H. Table 321. Formula I.8 wherein R¹ is Y-1 A, R⁴ is CH₃ and R⁵ is H. Table 322. Formula I.8 wherein R¹ is Y-1B, R⁴ is CH₃ and R⁵ is H. Table 323. Formula I.8 wherein R¹ is Y-2A, R⁴ is CH₃ and R⁵ is H. Table 324. Formula I.8 wherein R¹ is Y-2B, R⁴ is CH₃ and R⁵ is H. Table 325. Formula I.8 wherein R¹ is Y-3A, R⁴ is CH₃ and R⁵ is H. Table 326. Formula I.8 wherein R¹ is Y-3B, R⁴ is CH₃ and R⁵ is H. Table 327. Formula I.8 wherein R¹ is Y-3C, R⁴ is CH₃ and R⁵ is H. Table 328. Formula I.8 wherein R¹ is Y-3D, R⁴ is CH₃ and R⁵ is H. Table 329. Formula I.8 wherein R¹ is Y-4A, R⁴ is CH₃ and R⁵ is H. Table 330. Formula I.8 wherein R¹ is Y-4B, R⁴ is CH₃ and R⁵ is H. Table 331. Formula I.8 wherein R¹ is Y-4C, R⁴ is CH₃ and R⁵ is H. Table 332. Formula I.8 wherein R¹ is Y-4D, R⁴ is CH₃ and R⁵ is H. Table 333. Formula I.8 wherein R¹ is Y-5A, R⁴ is CH₃ and R⁵ is H. Table 334. Formula I.8 wherein R¹ is Y-5B, R⁴ is CH₃ and R⁵ is H. Table 335. Formula I.8 wherein R¹ is Y-6A, R⁴ is CH₃ and R⁵ is H. Table 336. Formula I.8 wherein R¹ is Y-6B, R⁴ is CH₃ and R⁵ is H. Table 337. Formula I.8 wherein R¹ is Y-7A, R⁴ is CH₃ and R⁵ is H. Table 338. Formula I.8 wherein R¹ is Y-7B, R⁴ is CH₃ and R⁵ is H. Table 339. Formula I.8 wherein R¹ is Y-8A, R⁴ is CH₃ and R⁵ is H. Table 340. Formula I.8 wherein R¹ is Y-8B, R⁴ is CH₃ and R⁵ is H. Table 341. Formula I.8 wherein R¹ is Y-1 A, R⁴ is CH₃ and R⁵ is CH₃. Table 342. Formula I.8 wherein R¹ is Y-1B, R⁴ is CH₃ and R⁵ is CH₃. Table 343. Formula I.8 wherein R¹ is Y-2A, R⁴ is CH₃ and R⁵ is CH₃. Table 344. Formula I.8 wherein R¹ is Y-2B, R⁴ is CH₃ and R⁵ is CH₃. Table 345. Formula I.8 wherein R¹ is Y-3A, R⁴ is CH₃ and R⁵ is CH₃. Table 346. Formula I.8 wherein R¹ is Y-3B, R⁴ is CH₃ and R⁵ is CH₃. Table 347. Formula I.8 wherein R¹ is Y-3C, R⁴ is CH₃ and R⁵ is CH₃. Table 348. Formula I.8 wherein R¹ is Y-3D, R⁴ is CH₃ and R⁵ is CH₃. Table 349. Formula I.8 wherein R¹ is Y-4A, R⁴ is CH₃ and R⁵ is CH₃. Table 350. Formula I.8 wherein R¹ is Y-4B, R⁴ is CH₃ and R⁵ is CH₃. Table 351. Formula I.8 wherein R¹ is Y-4C, R⁴ is CH₃ and R⁵ is CH₃. Table 352. Formula I.8 wherein R¹ is Y-4D, R⁴ is CH₃ and R⁵ is CH₃. Table 353. Formula I.8 wherein R¹ is Y-5A, R⁴ is CH₃ and R⁵ is CH₃. Table 354. Formula I.8 wherein R¹ is Y-5B, R⁴ is CH₃ and R⁵ is CH₃. Table 355. Formula I.8 wherein R¹ is Y-6A, R⁴ is CH₃ and R⁵ is CH₃. Table 356. Formula I.8 wherein R¹ is Y-6B, R⁴ is CH₃ and R⁵ is CH₃. Table 357. Formula I.8 wherein R¹ is Y-7A, R⁴ is CH₃ and R⁵ is CH₃. Table 358. Formula I.8 wherein R¹ is Y-7B, R⁴ is CH₃ and R⁵ is CH₃. Table 359. Formula I.8 wherein R¹ is Y-8A, R⁴ is CH₃ and R⁵ is CH₃. Table 360. Formula I.8 wherein R¹ is Y-8B, R⁴ is CH₃ and R⁵ is CH₃. Table 361. Formula I.13 wherein R¹ is Y-1 A, R² is H, R⁹ is H and R¹⁰ is H. Table 362. Formula I.13 wherein R¹ is Y-1 A, R² is H, R⁹ is CH₃ and, R¹⁰ is H. Table 363. Formula I.13 wherein R¹ is Y-1 A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 364. Formula I.13 wherein R¹ is Y-1B, R² is H, R⁹ is H and R¹⁰ is H. Table 365. Formula I.13 wherein R¹ is Y-1B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 366. Formula I.13 wherein R¹ is Y-1B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 367. Formula I.13 wherein R¹ is Y-2A, R² is H, R⁹ is H and R¹⁰ is H. Table 368. Formula I.13 wherein R¹ is Y-2A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 369. Formula I.13 wherein R¹ is Y-2A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 370. Formula I.13 wherein R¹ is Y-2B, R² is H, R⁹ is H and R¹⁰ is H. Table 371. Formula I.13 wherein R¹ is Y-2B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 372. Formula I.13 wherein R¹ is Y-2B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 373. Formula I.13 wherein R¹ is Y-3A, R² is H, R⁹ is H and R¹⁰ is H. Table 374. Formula I.13 wherein R¹ is Y-3A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 375. Formula I.13 wherein R¹ is Y-3A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 376. Formula I.13 wherein R¹ is Y-3B, R² is H, R⁹ is H and R¹⁰ is H. Table 377. Formula I.13 wherein R¹ is Y-3B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 378. Formula I.13 wherein R¹ is Y-3B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 379. Formula I.13 wherein R¹ is Y-3C, R² is H, R⁹ is H and R¹⁰ is H. Table 380. Formula I.13 wherein R¹ is Y-3C, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 381. Formula I.13 wherein R¹ is Y-3C, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 382. Formula I.13 wherein R¹ is Y-3D, R² is H, R⁹ is H and R¹⁰ is H. Table 383. Formula I.13 wherein R¹ is Y-3D, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 384. Formula I.13 wherein R¹ is Y-3D, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 385. Formula I.13 wherein R¹ is Y-4A, R² is H, R⁹ is H and R¹⁰ is H. Table 386. Formula I.13 wherein R¹ is Y-4A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 387. Formula I.13 wherein R¹ is Y-4A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 388. Formula I.13 wherein R¹ is Y-4B, R² is H, R⁹ is H and R¹⁰ is H. Table 389. Formula I.13 wherein R¹ is Y-4B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 390. Formula I.13 wherein R¹ is Y-4B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 391. Formula I.13 wherein R¹ is Y-4C, R² is H, R⁹ is H and R¹⁰ is H. Table 392. Formula I.13 wherein R¹ is Y-4C, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 393. Formula I.13 wherein R¹ is Y-4C, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 394. Formula I.13 wherein R¹ is Y-4D, R² is H, R⁹ is H and R¹⁰ is H. Table 395. Formula I.13 wherein R¹ is Y-4D, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 396. Formula I.13 wherein R¹ is Y-4D, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 397. Formula I.13 wherein R¹ is Y-5A, R² is H, R⁹ is H and R¹⁰ is H. Table 398. Formula I.13 wherein R¹ is Y-5A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 399. Formula I.13 wherein R¹ is Y-5A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 400. Formula I.13 wherein R¹ is Y-5B, R² is H, R⁹ is H and R¹⁰ is H. Table 401. Formula I.13 wherein R¹ is Y-5B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 402. Formula I.13 wherein R¹ is Y-5B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 403. Formula I.13 wherein R¹ is Y-6A, R² is H, R⁹ is H and R¹⁰ is H. Table 404. Formula I.13 wherein R¹ is Y-6A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 405. Formula I.13 wherein R¹ is Y-6A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 406. Formula I.13 wherein R¹ is Y-6B, R² is H, R⁹ is H and R¹⁰ is H. Table 407. Formula I.13 wherein R¹ is Y-6B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 408. Formula I.13 wherein R¹ is Y-6B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 409. Formula I.13 wherein R¹ is Y-7A, R² is H, R⁹ is H and R¹⁰ is H. Table 410. Formula I.13 wherein R¹ is Y-7A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 411. Formula I.13 wherein R¹ is Y-7A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 412. Formula I.13 wherein R¹ is Y-7B, R² is H, R⁹ is H and R¹⁰ is H. Table 413. Formula I.13 wherein R¹ is Y-7B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 414. Formula I.13 wherein R¹ is Y-7B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 415. Formula I.13 wherein R¹ is Y-8A, R² is H, R⁹ is H and R¹⁰ is H. Table 416. Formula I.13 wherein R¹ is Y-8A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 417. Formula I.13 wherein R¹ is Y-8A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 418. Formula I.13 wherein R¹ is Y-8B, R² is H, R⁹ is H and R¹⁰ is H. Table 419. Formula I.13 wherein R¹ is Y-8B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 420. Formula I.13 wherein R¹ is Y-8B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 421. Formula I.13 wherein R¹ is Y-1A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 422. Formula I.13 wherein R¹ is Y-1A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 423. Formula I.13 wherein R¹ is Y-1A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 424. Formula I.13 wherein R¹ is Y-1B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 425. Formula I.13 wherein R¹ is Y-1B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 426. Formula I.13 wherein R¹ is Y-1B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 427. Formula I.13 wherein R¹ is Y-2A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 428. Formula I.13 wherein R¹ is Y-2A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 429. Formula I.13 wherein R¹ is Y-2A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 430. Formula I.13 wherein R¹ is Y-2B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 431. Formula I.13 wherein R¹ is Y-2B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 432. Formula I.13 wherein R¹ is Y-2B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 433. Formula I.13 wherein R¹ is Y-3A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 434. Formula I.13 wherein R¹ is Y-3A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 435. Formula I.13 wherein R¹ is Y-3A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 436. Formula I.13 wherein R¹ is Y-3B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 437. Formula I.13 wherein R¹ is Y-3B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 438. Formula I.13 wherein R¹ is Y-3B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 439. Formula I.13 wherein R¹ is Y-3C, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 440. Formula I.13 wherein R¹ is Y-3C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 441. Formula I.13 wherein R¹ is Y-3C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 442. Formula I.13 wherein R¹ is Y-3D, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 443. Formula I.13 wherein R¹ is Y-3D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 444. Formula I.13 wherein R¹ is Y-3D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 445. Formula I.13 wherein R¹ is Y-4A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 446. Formula I.13 wherein R¹ is Y-4A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 447. Formula I.13 wherein R¹ is Y-4A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 448. Formula I.13 wherein R¹ is Y-4B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 449. Formula I.13 wherein R¹ is Y-4B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 450. Formula I.13 wherein R¹ is Y-4B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 451. Formula I.13 wherein R¹ is Y-4C, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 452. Formula I.13 wherein R¹ is Y-4C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 453. Formula I.13 wherein R¹ is Y-4C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 454. Formula I.13 wherein R¹ is Y-4D, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 455. Formula I.13 wherein R¹ is Y-4D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 456. Formula I.13 wherein R¹ is Y-4D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 457. Formula I.13 wherein R¹ is Y-5A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 458. Formula I.13 wherein R¹ is Y-5A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 459. Formula I.13 wherein R¹ is Y-5A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 460. Formula I.13 wherein R¹ is Y-5B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 461. Formula I.13 wherein R¹ is Y-5B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 462. Formula I.13 wherein R¹ is Y-5B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 463. Formula I.13 wherein R¹ is Y-6A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 464. Formula I.13 wherein R¹ is Y-6A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 465. Formula I.13 wherein R¹ is Y-6A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 466. Formula I.13 wherein R¹ is Y-6B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 467. Formula I.13 wherein R¹ is Y-6B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 468. Formula I.13 wherein R¹ is Y-6B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 469. Formula I.13 wherein R¹ is Y-7A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 470. Formula I.13 wherein R¹ is Y-7A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 471. Formula I.13 wherein R¹ is Y-7A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 472. Formula I.13 wherein R¹ is Y-7B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 473. Formula I.13 wherein R¹ is Y-7B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 474. Formula I.13 wherein R¹ is Y-7B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 475. Formula I.13 wherein R¹ is Y-8A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 476. Formula I.13 wherein R¹ is Y-8A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 477. Formula I.13 wherein R¹ is Y-8A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 478. Formula I.13 wherein R¹ is Y-8B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 479. Formula I.13 wherein R¹ is Y-8B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 480. Formula I.13 wherein R¹ is Y-8B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 481. Formula I.13 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 482. Formula I.13 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 483. Formula I.13 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 484. Formula I.13 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 485. Formula I.13 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 486. Formula I.13 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 487. Formula I.13 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 488. Formula I.13 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 489. Formula I.13 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 490. Formula I.13 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 491. Formula I.13 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 492. Formula I.13 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 493. Formula I.13 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 494. Formula I.13 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 495. Formula I.13 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 496. Formula I.13 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 497. Formula I.13 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 498. Formula I.13 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 499. Formula I.13 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 500. Formula I.13 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 501. Formula I.13 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 502. Formula I.13 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 503. Formula I.13 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 504. Formula I.13 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 505. Formula I.13 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 506. Formula I.13 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 507. Formula I.13 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 508. Formula I.13 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 509. Formula I.13 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 510. Formula I.13 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 511. Formula I.13 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 512. Formula I.13 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 513. Formula I.13 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 514. Formula I.13 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 515. Formula I.13 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 516. Formula I.13 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 517. Formula I.13 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 518. Formula I.13 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 519. Formula I.13 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 520. Formula I.13 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 521. Formula I.13 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 522. Formula I.13 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 523. Formula I.13 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 524. Formula I.13 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 525. Formula I.13 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 526. Formula I.13 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 527. Formula I.13 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 528. Formula I.13 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 529. Formula I.13 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 530. Formula I.13 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 531. Formula I.13 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 532. Formula I.13 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 533. Formula I.13 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 534. Formula I.13 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 535. Formula I.13 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 536. Formula I.13 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 537. Formula I.13 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 538. Formula I.13 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 539. Formula I.13 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 540. Formula I.13 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 541. Formula I.13 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 542. Formula I.13 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 543. Formula I.13 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 544. Formula I.13 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 545. Formula I.13 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is CH₃, R¹⁰ is H. Table 546. Formula I.13 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 547. Formula I.13 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 548. Formula I.13 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 549. Formula I.13 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 550. Formula I.13 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 551. Formula I.13 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 552. Formula I.13 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 553. Formula I.13 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 554. Formula I.13 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 555. Formula I.13 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 556. Formula I.13 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 557. Formula I.13 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 558. Formula I.13 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 559. Formula I.13 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 560. Formula I.13 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 561. Formula I.13 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 562. Formula I.13 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 563. Formula I.13 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 564. Formula I.13 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 565. Formula I.13 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 566. Formula I.13 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 567. Formula I.13 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 568. Formula I.13 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 569. Formula I.13 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 570. Formula I.13 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 571. Formula I.13 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 572. Formula I.13 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 573. Formula I.13 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 574. Formula I.13 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 575. Formula I.13 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 576. Formula I.13 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 577. Formula I.13 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 578. Formula I.13 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 579. Formula I.13 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 580. Formula I.13 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 581. Formula I.13 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 582. Formula I.13 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 583. Formula I.13 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 584. Formula I.13 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 585. Formula I.13 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 586. Formula I.13 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 587. Formula I.13 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 588. Formula I.13 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 589. Formula I.13 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 590. Formula I.13 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 591. Formula I.13 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 592. Formula I.13 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 593. Formula I.13 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 594. Formula I.13 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 595. Formula I.13 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 596. Formula I.13 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 597. Formula I.13 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 598. Formula I.13 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 599. Formula I.13 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 600. Formula I.13 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 601. Formula I.14 wherein R¹ is Y-1A, R² is H, R⁹ is H and R¹⁰ is H. Table 602. Formula I.14 wherein R¹ is Y-1A, R² is H, R⁹ is CH₃ and, R¹⁰ is H. Table 603. Formula I.14 wherein R¹ is Y-1A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 604. Formula I.14 wherein R¹ is Y-1B, R² is H, R⁹ is H and R¹⁰ is H. Table 605. Formula I.14 wherein R¹ is Y-1B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 606. Formula I.14 wherein R¹ is Y-1B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 607. Formula I.14 wherein R¹ is Y-2A, R² is H, R⁹ is H and R¹⁰ is H. Table 608. Formula I.14 wherein R¹ is Y-2A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 609. Formula I.14 wherein R¹ is Y-2A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 610. Formula I.14 wherein R¹ is Y-2B, R² is H, R⁹ is H and R¹⁰ is H. Table 611. Formula I.14 wherein R¹ is Y-2B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 612. Formula I.14 wherein R¹ is Y-2B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 613. Formula I.14 wherein R¹ is Y-3A, R² is H, R⁹ is H and R¹⁰ is H. Table 614. Formula I.14 wherein R¹ is Y-3A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 615. Formula I.14 wherein R¹ is Y-3A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 616. Formula I.14 wherein R¹ is Y-3B, R² is H, R⁹ is H and R¹⁰ is H. Table 617. Formula I.14 wherein R¹ is Y-3B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 618. Formula I.14 wherein R¹ is Y-3B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 619. Formula I.14 wherein R¹ is Y-3C, R² is H, R⁹ is H and R¹⁰ is H. Table 620. Formula I.14 wherein R¹ is Y-3C, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 621. Formula I.14 wherein R¹ is Y-3C, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 622. Formula I.14 wherein R¹ is Y-3D, R² is H, R⁹ is H and R¹⁰ is H. Table 623. Formula I.14 wherein R¹ is Y-3D, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 624. Formula I.14 wherein R¹ is Y-3D, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 625. Formula I.14 wherein R¹ is Y-4A, R² is H, R⁹ is H and R¹⁰ is H. Table 626. Formula I.14 wherein R¹ is Y-4A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 627. Formula I.14 wherein R¹ is Y-4A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 628. Formula I.14 wherein R¹ is Y-4B, R² is H, R⁹ is H and R¹⁰ is H. Table 629. Formula I.14 wherein R¹ is Y-4B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 630. Formula I.14 wherein R¹ is Y-4B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 631. Formula I.14 wherein R¹ is Y-4C, R² is H, R⁹ is H and R¹⁰ is H. Table 632. Formula I.14 wherein R¹ is Y-4C, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 633. Formula I.14 wherein R¹ is Y-4C, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 634. Formula I.14 wherein R¹ is Y-4D, R² is H, R⁹ is H and R¹⁰ is H. Table 635. Formula I.14 wherein R¹ is Y-4D, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 636. Formula I.14 wherein R¹ is Y-4D, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 637. Formula I.14 wherein R¹ is Y-5A, R² is H, R⁹ is H and R¹⁰ is H. Table 638. Formula I.14 wherein R¹ is Y-5A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 639. Formula I.14 wherein R¹ is Y-5A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 640. Formula I.14 wherein R¹ is Y-5B, R² is H, R⁹ is H and R¹⁰ is H. Table 641. Formula I.14 wherein R¹ is Y-5B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 642. Formula I.14 wherein R¹ is Y-5B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 643. Formula I.14 wherein R¹ is Y-6A, R² is H, R⁹ is H and R¹⁰ is H. Table 644. Formula I.14 wherein R¹ is Y-6A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 645. Formula I.14 wherein R¹ is Y-6A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 646. Formula I.14 wherein R¹ is Y-6B, R² is H, R⁹ is H and R¹⁰ is H. Table 647. Formula I.14 wherein R¹ is Y-6B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 648. Formula I.14 wherein R¹ is Y-6B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 649. Formula I.14 wherein R¹ is Y-7A, R² is H, R⁹ is H and R¹⁰ is H. Table 650. Formula I.14 wherein R¹ is Y-7A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 651. Formula I.14 wherein R¹ is Y-7A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 652. Formula I.14 wherein R¹ is Y-7B, R² is H, R⁹ is H and R¹⁰ is H. Table 653. Formula I.14 wherein R¹ is Y-7B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 654. Formula I.14 wherein R¹ is Y-7B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 655. Formula I.14 wherein R¹ is Y-8A, R² is H, R⁹ is H and R¹⁰ is H. Table 656. Formula I.14 wherein R¹ is Y-8A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 657. Formula I.14 wherein R¹ is Y-8A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 658. Formula I.14 wherein R¹ is Y-8B, R² is H, R⁹ is H and R¹⁰ is H. Table 659. Formula I.14 wherein R¹ is Y-8B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 660. Formula I.14 wherein R¹ is Y-8B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 661. Formula I.14 wherein R¹ is Y-1A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 662. Formula I.14 wherein R¹ is Y-1A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 663. Formula I.14 wherein R¹ is Y-1A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 664. Formula I.14 wherein R¹ is Y-1B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 665. Formula I.14 wherein R¹ is Y-1B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 666. Formula I.14 wherein R¹ is Y-1B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 667. Formula I.14 wherein R¹ is Y-2A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 668. Formula I.14 wherein R¹ is Y-2A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 669. Formula I.14 wherein R¹ is Y-2A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 670. Formula I.14 wherein R¹ is Y-2B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 671. Formula I.14 wherein R¹ is Y-2B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 672. Formula I.14 wherein R¹ is Y-2B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 673. Formula I.14 wherein R¹ is Y-3A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 674. Formula I.14 wherein R¹ is Y-3A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 675. Formula I.14 wherein R¹ is Y-3A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 676. Formula I.14 wherein R¹ is Y-3B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 677. Formula I.14 wherein R¹ is Y-3B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 678. Formula I.14 wherein R¹ is Y-3B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 679. Formula I.14 wherein R¹ is Y-3C, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 680. Formula I.14 wherein R¹ is Y-3C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 681. Formula I.14 wherein R¹ is Y-3C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 682. Formula I.14 wherein R¹ is Y-3D, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 683. Formula I.14 wherein R¹ is Y-3D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 684. Formula I.14 wherein R¹ is Y-3D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 685. Formula I.14 wherein R¹ is Y-4A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 686. Formula I.14 wherein R¹ is Y-4A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 687. Formula I.14 wherein R¹ is Y-4A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 688. Formula I.14 wherein R¹ is Y-4B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 689. Formula I.14 wherein R¹ is Y-4B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 690. Formula I.14 wherein R¹ is Y-4B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 691. Formula I.14 wherein R¹ is Y-4C, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 692. Formula I.14 wherein R¹ is Y-4C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 693. Formula I.14 wherein R¹ is Y-4C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 694. Formula I.14 wherein R¹ is Y-4D, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 695. Formula I.14 wherein R¹ is Y-4D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 696. Formula I.14 wherein R¹ is Y-4D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 697. Formula I.14 wherein R¹ is Y-5A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 698. Formula I.14 wherein R¹ is Y-5A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 699. Formula I.14 wherein R¹ is Y-5A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 700. Formula I.14 wherein R¹ is Y-5B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 701. Formula I.14 wherein R¹ is Y-5B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 702. Formula I.14 wherein R¹ is Y-5B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 703. Formula I.14 wherein R¹ is Y-6A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 704. Formula I.14 wherein R¹ is Y-6A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 705. Formula I.14 wherein R¹ is Y-6A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 706. Formula I.14 wherein R¹ is Y-6B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 707. Formula I.14 wherein R¹ is Y-6B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 708. Formula I.14 wherein R¹ is Y-6B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 709. Formula I.14 wherein R¹ is Y-7A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 710. Formula I.14 wherein R¹ is Y-7A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 711. Formula I.14 wherein R¹ is Y-7A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 712. Formula I.14 wherein R¹ is Y-7B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 713. Formula I.14 wherein R¹ is Y-7B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 714. Formula I.14 wherein R¹ is Y-7B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 715. Formula I.14 wherein R¹ is Y-8A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 716. Formula I.14 wherein R¹ is Y-8A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 717. Formula I.14 wherein R¹ is Y-8A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 718. Formula I.14 wherein R¹ is Y-8B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 719. Formula I.14 wherein R¹ is Y-8B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 720. Formula I.14 wherein R¹ is Y-8B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 721. Formula I.14 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 722. Formula I.14 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 723. Formula I.14 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 724. Formula I.14 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 725. Formula I.14 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 726. Formula I.14 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 727. Formula I.14 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 728. Formula I.14 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 729. Formula I.14 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 730. Formula I.14 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 731. Formula I.14 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 732. Formula I.14 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 733. Formula I.14 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 734. Formula I.14 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 735. Formula I.14 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 736. Formula I.14 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 737. Formula I.14 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 738. Formula I.14 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 739. Formula I.14 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 740. Formula I.14 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 741. Formula I.14 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 742. Formula I.14 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 743. Formula I.14 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 744. Formula I.14 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 745. Formula I.14 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 746. Formula I.14 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 747. Formula I.14 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 748. Formula I.14 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 749. Formula I.14 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 750. Formula I.14 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 751. Formula I.14 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 752. Formula I.14 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 753. Formula I.14 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 754. Formula I.14 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 755. Formula I.14 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 756. Formula I.14 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 757. Formula I.14 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 758. Formula I.14 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 759. Formula I.14 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 760. Formula I.14 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 761. Formula I.14 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 762. Formula I.14 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 763. Formula I.14 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 764. Formula I.14 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 765. Formula I.14 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 766. Formula I.14 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 767. Formula I.14 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 768. Formula I.14 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 769. Formula I.14 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 770. Formula I.14 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 771. Formula I.14 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 772. Formula I.14 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 773. Formula I.14 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 774. Formula I.14 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 775. Formula I.14 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 776. Formula I.14 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 777. Formula I.14 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 778. Formula I.14 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 779. Formula I.14 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 780. Formula I.14 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 781. Formula I.14 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 782. Formula I.14 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 783. Formula I.14 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 784. Formula I.14 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 785. Formula I.14 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is CH₃, R¹⁰ is H. Table 786. Formula I.14 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 787. Formula I.14 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 788. Formula I.14 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 789. Formula I.14 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 790. Formula I.14 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 791. Formula I.14 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 792. Formula I.14 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 793. Formula I.14 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 794. Formula I.14 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 795. Formula I.14 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 796. Formula I.14 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 797. Formula I.14 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 798. Formula I.14 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 799. Formula I.14 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 800. Formula I.14 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 801. Formula I.14 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 802. Formula I.14 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 803. Formula I.14 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 804. Formula I.14 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 805. Formula I.14 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 806. Formula I.14 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 807. Formula I.14 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 808. Formula I.14 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 809. Formula I.14 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 810. Formula I.14 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 811. Formula I.14 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 812. Formula I.14 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 813. Formula I.14 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 814. Formula I.14 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 815. Formula I.14 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 816. Formula I.14 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 817. Formula I.14 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 818. Formula I.14 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 819. Formula I.14 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 820. Formula I.14 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 821. Formula I.14 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 822. Formula I.14 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 823. Formula I.14 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 824. Formula I.14 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 825. Formula I.14 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 826. Formula I.14 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 827. Formula I.14 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 828. Formula I.14 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 829. Formula I.14 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 830. Formula I.14 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 831. Formula I.14 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 832. Formula I.14 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 833. Formula I.14 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 834. Formula I.14 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 835. Formula I.14 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 836. Formula I.14 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 837. Formula I.14 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 838. Formula I.14 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 839. Formula I.14 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 840. Formula I.14 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 841. Formula I.17 wherein R¹ is Y-1A, R² is H, R⁹ is H and R¹⁰ is H. Table 842. Formula I.17 wherein R¹ is Y-1A, R² is H, R⁹ is CH₃ and, R¹⁰ is H. Table 843. Formula I.17 wherein R¹ is Y-1A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 844. Formula I.17 wherein R¹ is Y-1B, R² is H, R⁹ is H and R¹⁰ is H. Table 845. Formula I.17 wherein R¹ is Y-1B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 846. Formula I.17 wherein R¹ is Y-1B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 847. Formula I.17 wherein R¹ is Y-2A, R² is H, R⁹ is H and R¹⁰ is H. Table 848. Formula I.17 wherein R¹ is Y-2A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 849. Formula I.17 wherein R¹ is Y-2A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 850. Formula I.17 wherein R¹ is Y-2B, R² is H, R⁹ is H and R¹⁰ is H. Table 851. Formula I.17 wherein R¹ is Y-2B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 852. Formula I.17 wherein R¹ is Y-2B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 853. Formula I.17 wherein R¹ is Y-3A, R² is H, R⁹ is H and R¹⁰ is H. Table 854. Formula I.17 wherein R¹ is Y-3A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 855. Formula I.17 wherein R¹ is Y-3A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 856. Formula I.17 wherein R¹ is Y-3B, R² is H, R⁹ is H and R¹⁰ is H. Table 857. Formula I.17 wherein R¹ is Y-3B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 858. Formula I.17 wherein R¹ is Y-3B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 859. Formula I.17 wherein R¹ is Y-3C, R² is H, R⁹ is H and R¹⁰ is H. Table 860. Formula I.17 wherein R¹ is Y-3C, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 861. Formula I.17 wherein R¹ is Y-3C, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 862. Formula I.17 wherein R¹ is Y-3D, R² is H, R⁹ is H and R¹⁰ is H. Table 863. Formula I.17 wherein R¹ is Y-3D, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 864. Formula I.17 wherein R¹ is Y-3D, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 865. Formula I.17 wherein R¹ is Y-4A, R² is H, R⁹ is H and R¹⁰ is H. Table 866. Formula I.17 wherein R¹ is Y-4A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 867. Formula I.17 wherein R¹ is Y-4A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 868. Formula I.17 wherein R¹ is Y-4B, R² is H, R⁹ is H and R¹⁰ is H. Table 869. Formula I.17 wherein R¹ is Y-4B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 870. Formula I.17 wherein R¹ is Y-4B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 871. Formula I.17 wherein R¹ is Y-4C, R² is H, R⁹ is H and R¹⁰ is H. Table 872. Formula I.17 wherein R¹ is Y-4C, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 873. Formula I.17 wherein R¹ is Y-4C, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 874. Formula I.17 wherein R¹ is Y-4D, R² is H, R⁹ is H and R¹⁰ is H. Table 875. Formula I.17 wherein R¹ is Y-4D, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 876. Formula I.17 wherein R¹ is Y-4D, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 877. Formula I.17 wherein R¹ is Y-5A, R² is H, R⁹ is H and R¹⁰ is H. Table 878. Formula I.17 wherein R¹ is Y-5A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 879. Formula I.17 wherein R¹ is Y-5A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 880. Formula I.17 wherein R¹ is Y-5B, R² is H, R⁹ is H and R¹⁰ is H. Table 881. Formula I.17 wherein R¹ is Y-5B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 882. Formula I.17 wherein R¹ is Y-5B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 883. Formula I.17 wherein R¹ is Y-6A, R² is H, R⁹ is H and R¹⁰ is H. Table 884. Formula I.17 wherein R¹ is Y-6A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 885. Formula I.17 wherein R¹ is Y-6A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 886. Formula I.17 wherein R¹ is Y-6B, R² is H, R⁹ is H and R¹⁰ is H. Table 887. Formula I.17 wherein R¹ is Y-6B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 888. Formula I.17 wherein R¹ is Y-6B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 889. Formula I.17 wherein R¹ is Y-7A, R² is H, R⁹ is H and R¹⁰ is H. Table 890. Formula I.17 wherein R¹ is Y-7A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 891. Formula I.17 wherein R¹ is Y-7A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 892. Formula I.17 wherein R¹ is Y-7B, R² is H, R⁹ is H and R¹⁰ is H. Table 893. Formula I.17 wherein R¹ is Y-7B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 894. Formula I.17 wherein R¹ is Y-7B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 895. Formula I.17 wherein R¹ is Y-8A, R² is H, R⁹ is H and R¹⁰ is H. Table 896. Formula I.17 wherein R¹ is Y-8A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 897. Formula I.17 wherein R¹ is Y-8A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 898. Formula I.17 wherein R¹ is Y-8B, R² is H, R⁹ is H and R¹⁰ is H. Table 899. Formula I.17 wherein R¹ is Y-8B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 900. Formula I.17 wherein R¹ is Y-8B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 901. Formula I.17 wherein R¹ is Y-1A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 902. Formula I.17 wherein R¹ is Y-1A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 903. Formula I.17 wherein R¹ is Y-1A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 904. Formula I.17 wherein R¹ is Y-1B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 905. Formula I.17 wherein R¹ is Y-1B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 906. Formula I.17 wherein R¹ is Y-1B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 907. Formula I.17 wherein R¹ is Y-2A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 908. Formula I.17 wherein R¹ is Y-2A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 909. Formula I.17 wherein R¹ is Y-2A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 910. Formula I.17 wherein R¹ is Y-2B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 911. Formula I.17 wherein R¹ is Y-2B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 912. Formula I.17 wherein R¹ is Y-2B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 913. Formula I.17 wherein R¹ is Y-3A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 914. Formula I.17 wherein R¹ is Y-3A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 915. Formula I.17 wherein R¹ is Y-3A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 916. Formula I.17 wherein R¹ is Y-3B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 917. Formula I.17 wherein R¹ is Y-3B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 918. Formula I.17 wherein R¹ is Y-3B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 919. Formula I.17 wherein R¹ is Y-3C, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 920. Formula I.17 wherein R¹ is Y-3C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 921. Formula I.17 wherein R¹ is Y-3C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 922. Formula I.17 wherein R¹ is Y-3D, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 923. Formula I.17 wherein R¹ is Y-3D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 924. Formula I.17 wherein R¹ is Y-3D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 925. Formula I.17 wherein R¹ is Y-4A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 926. Formula I.17 wherein R¹ is Y-4A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 927. Formula I.17 wherein R¹ is Y-4A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 928. Formula I.17 wherein R¹ is Y-4B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 929. Formula I.17 wherein R¹ is Y-4B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 930. Formula I.17 wherein R¹ is Y-4B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 931. Formula I.17 wherein R¹ is Y-4C, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 932. Formula I.17 wherein R¹ is Y-4C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 933. Formula I.17 wherein R¹ is Y-4C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 934. Formula I.17 wherein R¹ is Y-4D, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 935. Formula I.17 wherein R¹ is Y-4D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 936. Formula I.17 wherein R¹ is Y-4D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 937. Formula I.17 wherein R¹ is Y-5A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 938. Formula I.17 wherein R¹ is Y-5A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 939. Formula I.17 wherein R¹ is Y-5A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 940. Formula I.17 wherein R¹ is Y-5B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 941. Formula I.17 wherein R¹ is Y-5B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 942. Formula I.17 wherein R¹ is Y-5B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 943. Formula I.17 wherein R¹ is Y-6A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 944. Formula I.17 wherein R¹ is Y-6A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 945. Formula I.17 wherein R¹ is Y-6A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 946. Formula I.17 wherein R¹ is Y-6B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 947. Formula I.17 wherein R¹ is Y-6B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 948. Formula I.17 wherein R¹ is Y-6B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 949. Formula I.17 wherein R¹ is Y-7A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 950. Formula I.17 wherein R¹ is Y-7A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 951. Formula I.17 wherein R¹ is Y-7A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 952. Formula I.17 wherein R¹ is Y-7B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 953. Formula I.17 wherein R¹ is Y-7B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 954. Formula I.17 wherein R¹ is Y-7B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 955. Formula I.17 wherein R¹ is Y-8A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 956. Formula I.17 wherein R¹ is Y-8A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 957. Formula I.17 wherein R¹ is Y-8A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 958. Formula I.17 wherein R¹ is Y-8B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 959. Formula I.17 wherein R¹ is Y-8B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 960. Formula I.17 wherein R¹ is Y-8B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 961. Formula I.17 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 962. Formula I.17 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 963. Formula I.17 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 964. Formula I.17 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 965. Formula I.17 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 966. Formula I.17 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 967. Formula I.17 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 968. Formula I.17 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 969. Formula I.17 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 970. Formula I.17 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 971. Formula I.17 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 972. Formula I.17 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 973. Formula I.17 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 974. Formula I.17 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 975. Formula I.17 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 976. Formula I.17 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 977. Formula I.17 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 978. Formula I.17 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 979. Formula I.17 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 980. Formula I.17 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 981. Formula I.17 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 982. Formula I.17 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 983. Formula I.17 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 984. Formula I.17 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 985. Formula I.17 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 986. Formula I.17 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 987. Formula I.17 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 988. Formula I.17 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 989. Formula I.17 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 990. Formula I.17 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 991. Formula I.17 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 992. Formula I.17 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 993. Formula I.17 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 994. Formula I.17 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 995. Formula I.17 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 996. Formula I.17 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 997. Formula I.17 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 998. Formula I.17 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 999. Formula I.17 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1000. Formula I.17 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1001. Formula I.17 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1002. Formula I.17 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1003. Formula I.17 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1004. Formula I.17 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1005. Formula I.17 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1006. Formula I.17 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1007. Formula I.17 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1008. Formula I.17 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1009. Formula I.17 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1010. Formula I.17 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1011. Formula I.17 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1012. Formula I.17 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1013. Formula I.17 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1014. Formula I.17 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1015. Formula I.17 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1016. Formula I.17 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1017. Formula I.17 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1018. Formula I.17 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1019. Formula I.17 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1020. Formula I.17 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1021. Formula I.17 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1022. Formula I.17 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1023. Formula I.17 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1024. Formula I.17 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1025. Formula I.17 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is CH₃, R¹⁰ is H. Table 1026. Formula I.17 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1027. Formula I.17 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1028. Formula I.17 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1029. Formula I.17 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1030. Formula I.17 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1031. Formula I.17 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1032. Formula I.17 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1033. Formula I.17 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1034. Formula I.17 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1035. Formula I.17 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1036. Formula I.17 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1037. Formula I.17 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1038. Formula I.17 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1039. Formula I.17 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1040. Formula I.17 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1041. Formula I.17 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1042. Formula I.17 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1043. Formula I.17 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1044. Formula I.17 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1045. Formula I.17 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1046. Formula I.17 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1047. Formula I.17 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1048. Formula I.17 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1049. Formula I.17 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1050. Formula I.17 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1051. Formula I.17 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1052. Formula I.17 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1053. Formula I.17 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1054. Formula I.17 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1055. Formula I.17 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1056. Formula I.17 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1057. Formula I.17 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1058. Formula I.17 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1059. Formula I.17 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1060. Formula I.17 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1061. Formula I.17 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1062. Formula I.17 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1063. Formula I.17 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1064. Formula I.17 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1065. Formula I.17 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1066. Formula I.17 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1067. Formula I.17 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1068. Formula I.17 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1069. Formula I.17 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1070. Formula I.17 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1071. Formula I.17 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1072. Formula I.17 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1073. Formula I.17 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1074. Formula I.17 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1075. Formula I.17 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1076. Formula I.17 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1077. Formula I.17 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1078. Formula I.17 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1079. Formula I.17 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1080. Formula I.17 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1081. Formula I.18 wherein R¹ is Y-1A, R² is H, R⁹ is H and R¹⁰ is H. Table 1082. Formula I.18 wherein R¹ is Y-1A, R² is H, R⁹ is CH₃ and, R¹⁰ is H. Table 1083. Formula I.18 wherein R¹ is Y-1A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1084. Formula I.18 wherein R¹ is Y-1B, R² is H, R⁹ is H and R¹⁰ is H. Table 1085. Formula I.18 wherein R¹ is Y-1B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1086. Formula I.18 wherein R¹ is Y-1B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1087. Formula I.18 wherein R¹ is Y-2A, R² is H, R⁹ is H and R¹⁰ is H. Table 1088. Formula I.18 wherein R¹ is Y-2A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1089. Formula I.18 wherein R¹ is Y-2A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1090. Formula I.18 wherein R¹ is Y-2B, R² is H, R⁹ is H and R¹⁰ is H. Table 1091. Formula I.18 wherein R¹ is Y-2B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1092. Formula I.18 wherein R¹ is Y-2B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1093. Formula I.18 wherein R¹ is Y-3A, R² is H, R⁹ is H and R¹⁰ is H. Table 1094. Formula I.18 wherein R¹ is Y-3A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1095. Formula I.18 wherein R¹ is Y-3A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1096. Formula I.18 wherein R¹ is Y-3B, R² is H, R⁹ is H and R¹⁰ is H. Table 1097. Formula I.18 wherein R¹ is Y-3B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1098. Formula I.18 wherein R¹ is Y-3B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1099. Formula I.18 wherein R¹ is Y-3C, R² is H, R⁹ is H and R¹⁰ is H. Table 1100. Formula I.18 wherein R¹ is Y-3C, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1101. Formula I.18 wherein R¹ is Y-3C, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1102. Formula I.18 wherein R¹ is Y-3D, R² is H, R⁹ is H and R¹⁰ is H. Table 1103. Formula I.18 wherein R¹ is Y-3D, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1104. Formula I.18 wherein R¹ is Y-3D, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1105. Formula I.18 wherein R¹ is Y-4A, R² is H, R⁹ is H and R¹⁰ is H. Table 1106. Formula I.18 wherein R¹ is Y-4A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1107. Formula I.18 wherein R¹ is Y-4A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1108. Formula I.18 wherein R¹ is Y-4B, R² is H, R⁹ is H and R¹⁰ is H. Table 1109. Formula I.18 wherein R¹ is Y-4B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1110. Formula I.18 wherein R¹ is Y-4B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1111. Formula I.18 wherein R¹ is Y-4C, R² is H, R⁹ is H and R¹⁰ is H. Table 1112. Formula I.18 wherein R¹ is Y-4C, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1113. Formula I.18 wherein R¹ is Y-4C, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1114. Formula I.18 wherein R¹ is Y-4D, R² is H, R⁹ is H and R¹⁰ is H. Table 1115. Formula I.18 wherein R¹ is Y-4D, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1116. Formula I.18 wherein R¹ is Y-4D, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1117. Formula I.18 wherein R¹ is Y-5A, R² is H, R⁹ is H and R¹⁰ is H. Table 1118. Formula I.18 wherein R¹ is Y-5A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1119. Formula I.18 wherein R¹ is Y-5A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1120. Formula I.18 wherein R¹ is Y-5B, R² is H, R⁹ is H and R¹⁰ is H. Table 1121. Formula I.18 wherein R¹ is Y-5B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1122. Formula I.18 wherein R¹ is Y-5B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1123. Formula I.18 wherein R¹ is Y-6A, R² is H, R⁹ is H and R¹⁰ is H. Table 1124. Formula I.18 wherein R¹ is Y-6A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1125. Formula I.18 wherein R¹ is Y-6A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1126. Formula I.18 wherein R¹ is Y-6B, R² is H, R⁹ is H and R¹⁰ is H. Table 1127. Formula I.18 wherein R¹ is Y-6B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1128. Formula I.18 wherein R¹ is Y-6B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1129. Formula I.18 wherein R¹ is Y-7A, R² is H, R⁹ is H and R¹⁰ is H. Table 1130. Formula I.18 wherein R¹ is Y-7A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1131. Formula I.18 wherein R¹ is Y-7A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1132. Formula I.18 wherein R¹ is Y-7B, R² is H, R⁹ is H and R¹⁰ is H. Table 1133. Formula I.18 wherein R¹ is Y-7B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1134. Formula I.18 wherein R¹ is Y-7B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1135. Formula I.18 wherein R¹ is Y-8A, R² is H, R⁹ is H and R¹⁰ is H. Table 1136. Formula I.18 wherein R¹ is Y-8A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1137. Formula I.18 wherein R¹ is Y-8A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1138. Formula I.18 wherein R¹ is Y-8B, R² is H, R⁹ is H and R¹⁰ is H. Table 1139. Formula I.18 wherein R¹ is Y-8B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1140. Formula I.18 wherein R¹ is Y-8B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1141. Formula I.18 wherein R¹ is Y-1A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1142. Formula I.18 wherein R¹ is Y-1A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1143. Formula I.18 wherein R¹ is Y-1A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1144. Formula I.18 wherein R¹ is Y-1B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1145. Formula I.18 wherein R¹ is Y-1B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1146. Formula I.18 wherein R¹ is Y-1B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1147. Formula I.18 wherein R¹ is Y-2A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1148. Formula I.18 wherein R¹ is Y-2A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1149. Formula I.18 wherein R¹ is Y-2A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1150. Formula I.18 wherein R¹ is Y-2B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1151. Formula I.18 wherein R¹ is Y-2B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1152. Formula I.18 wherein R¹ is Y-2B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1153. Formula I.18 wherein R¹ is Y-3A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1154. Formula I.18 wherein R¹ is Y-3A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1155. Formula I.18 wherein R¹ is Y-3A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1156. Formula I.18 wherein R¹ is Y-3B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1157. Formula I.18 wherein R¹ is Y-3B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1158. Formula I.18 wherein R¹ is Y-3B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1159. Formula I.18 wherein R¹ is Y-3C, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1160. Formula I.18 wherein R¹ is Y-3C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1161. Formula I.18 wherein R¹ is Y-3C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1162. Formula I.18 wherein R¹ is Y-3D, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1163. Formula I.18 wherein R¹ is Y-3D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1164. Formula I.18 wherein R¹ is Y-3D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1165. Formula I.18 wherein R¹ is Y-4A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1166. Formula I.18 wherein R¹ is Y-4A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1167. Formula I.18 wherein R¹ is Y-4A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1168. Formula I.18 wherein R¹ is Y-4B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1169. Formula I.18 wherein R¹ is Y-4B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1170. Formula I.18 wherein R¹ is Y-4B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1171. Formula I.18 wherein R¹ is Y-4C, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1172. Formula I.18 wherein R¹ is Y-4C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1173. Formula I.18 wherein R¹ is Y-4C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1174. Formula I.18 wherein R¹ is Y-4D, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1175. Formula I.18 wherein R¹ is Y-4D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1176. Formula I.18 wherein R¹ is Y-4D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1177. Formula I.18 wherein R¹ is Y-5A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1178. Formula I.18 wherein R¹ is Y-5A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1179. Formula I.18 wherein R¹ is Y-5A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1180. Formula I.18 wherein R¹ is Y-5B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1181. Formula I.18 wherein R¹ is Y-5B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1182. Formula I.18 wherein R¹ is Y-5B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1183. Formula I.18 wherein R¹ is Y-6A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1184. Formula I.18 wherein R¹ is Y-6A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1185. Formula I.18 wherein R¹ is Y-6A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1186. Formula I.18 wherein R¹ is Y-6B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1187. Formula I.18 wherein R¹ is Y-6B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1188. Formula I.18 wherein R¹ is Y-6B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1189. Formula I.18 wherein R¹ is Y-7A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1190. Formula I.18 wherein R¹ is Y-7A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1191. Formula I.18 wherein R¹ is Y-7A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1192. Formula I.18 wherein R¹ is Y-7B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1193. Formula I.18 wherein R¹ is Y-7B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1194. Formula I.18 wherein R¹ is Y-7B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1195. Formula I.18 wherein R¹ is Y-8A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1196. Formula I.18 wherein R¹ is Y-8A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1197. Formula I.18 wherein R¹ is Y-8A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1198. Formula I.18 wherein R¹ is Y-8B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1199. Formula I.18 wherein R¹ is Y-8B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1200. Formula I.18 wherein R¹ is Y-8B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1201. Formula I.18 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1202. Formula I.18 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1203. Formula I.18 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1204. Formula I.18 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1205. Formula I.18 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1206. Formula I.18 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1207. Formula I.18 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1208. Formula I.18 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1209. Formula I.18 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1210. Formula I.18 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1211. Formula I.18 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1212. Formula I.18 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1213. Formula I.18 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1214. Formula I.18 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1215. Formula I.18 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1216. Formula I.18 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1217. Formula I.18 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1218. Formula I.18 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1219. Formula I.18 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1220. Formula I.18 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1221. Formula I.18 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1222. Formula I.18 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1223. Formula I.18 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1224. Formula I.18 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1225. Formula I.18 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1226. Formula I.18 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1227. Formula I.18 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1228. Formula I.18 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1229. Formula I.18 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1230. Formula I.18 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1231. Formula I.18 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1232. Formula I.18 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1233. Formula I.18 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1234. Formula I.18 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1235. Formula I.18 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1236. Formula I.18 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1237. Formula I.18 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1238. Formula I.18 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1239. Formula I.18 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1240. Formula I.18 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1241. Formula I.18 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1242. Formula I.18 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1243. Formula I.18 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1244. Formula I.18 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1245. Formula I.18 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1246. Formula I.18 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1247. Formula I.18 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1248. Formula I.18 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1249. Formula I.18 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1250. Formula I.18 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1251. Formula I.18 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1252. Formula I.18 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1253. Formula I.18 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1254. Formula I.18 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1255. Formula I.18 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1256. Formula I.18 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1257. Formula I.18 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1258. Formula I.18 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1259. Formula I.18 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1260. Formula I.18 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1261. Formula I.18 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1262. Formula I.18 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1263. Formula I.18 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1264. Formula I.18 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1265. Formula I.18 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is CH₃, R¹⁰ is H. Table 1266. Formula I.18 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1267. Formula I.18 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1268. Formula I.18 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1269. Formula I.18 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1270. Formula I.18 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1271. Formula I.18 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1272. Formula I.18 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1273. Formula I.18 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1274. Formula I.18 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1275. Formula I.18 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1276. Formula I.18 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1277. Formula I.18 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1278. Formula I.18 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1279. Formula I.18 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1280. Formula I.18 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1281. Formula I.18 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1282. Formula I.18 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1283. Formula I.18 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1284. Formula I.18 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1285. Formula I.18 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1286. Formula I.18 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1287. Formula I.18 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1288. Formula I.18 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1289. Formula I.18 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1290. Formula I.18 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1291. Formula I.18 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1292. Formula I.18 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1293. Formula I.18 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1294. Formula I.18 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1295. Formula I.18 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1296. Formula I.18 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1297. Formula I.18 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1298. Formula I.18 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1299. Formula I.18 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1300. Formula I.18 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1301. Formula I.18 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1302. Formula I.18 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1303. Formula I.18 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1304. Formula I.18 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1305. Formula I.18 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1306. Formula I.18 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1307. Formula I.18 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1308. Formula I.18 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1309. Formula I.18 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1310. Formula I.18 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1311. Formula I.18 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1312. Formula I.18 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1313. Formula I.18 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1314. Formula I.18 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1315. Formula I.18 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1316. Formula I.18 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1317. Formula I.18 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1318. Formula I.18 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1319. Formula I.18 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1320. Formula I.18 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1321. Formula I.19 wherein R¹ is Y-1A, R² is H, R⁹ is H and R¹⁰ is H. Table 1322. Formula I.19 wherein R¹ is Y-1A, R² is H, R⁹ is CH₃ and, R¹⁰ is H. Table 1323. Formula I.19 wherein R¹ is Y-1A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1324. Formula I.19 wherein R¹ is Y-1B, R² is H, R⁹ is H and R¹⁰ is H. Table 1325. Formula I.19 wherein R¹ is Y-1B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1326. Formula I.19 wherein R¹ is Y-1B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1327. Formula I.19 wherein R¹ is Y-2A, R² is H, R⁹ is H and R¹⁰ is H. Table 1328. Formula I.19 wherein R¹ is Y-2A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1329. Formula I.19 wherein R¹ is Y-2A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1330. Formula I.19 wherein R¹ is Y-2B, R² is H, R⁹ is H and R¹⁰ is H. Table 1331. Formula I.19 wherein R¹ is Y-2B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1332. Formula I.19 wherein R¹ is Y-2B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1333. Formula I.19 wherein R¹ is Y-3A, R² is H, R⁹ is H and R¹⁰ is H. Table 1334. Formula I.19 wherein R¹ is Y-3A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1335. Formula I.19 wherein R¹ is Y-3A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1336. Formula I.19 wherein R¹ is Y-3B, R² is H, R⁹ is H and R¹⁰ is H. Table 1337. Formula I.19 wherein R¹ is Y-3B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1338. Formula I.19 wherein R¹ is Y-3B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1339. Formula I.19 wherein R¹ is Y-3C, R² is H, R⁹ is H and R¹⁰ is H. Table 1340. Formula I.19 wherein R¹ is Y-3C, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1341. Formula I.19 wherein R¹ is Y-3C, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1342. Formula I.19 wherein R¹ is Y-3D, R² is H, R⁹ is H and R¹⁰ is H. Table 1343. Formula I.19 wherein R¹ is Y-3D, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1344. Formula I.19 wherein R¹ is Y-3D, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1345. Formula I.19 wherein R¹ is Y-4A, R² is H, R⁹ is H and R¹⁰ is H. Table 1346. Formula I.19 wherein R¹ is Y-4A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1347. Formula I.19 wherein R¹ is Y-4A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1348. Formula I.19 wherein R¹ is Y-4B, R² is H, R⁹ is H and R¹⁰ is H. Table 1349. Formula I.19 wherein R¹ is Y-4B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1350. Formula I.19 wherein R¹ is Y-4B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1351. Formula I.19 wherein R¹ is Y-4C, R² is H, R⁹ is H and R¹⁰ is H. Table 1352. Formula I.19 wherein R¹ is Y-4C, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1353. Formula I.19 wherein R¹ is Y-4C, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1354. Formula I.19 wherein R¹ is Y-4D, R² is H, R⁹ is H and R¹⁰ is H. Table 1355. Formula I.19 wherein R¹ is Y-4D, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1356. Formula I.19 wherein R¹ is Y-4D, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1357. Formula I.19 wherein R¹ is Y-5A, R² is H, R⁹ is H and R¹⁰ is H. Table 1358. Formula I.19 wherein R¹ is Y-5A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1359. Formula I.19 wherein R¹ is Y-5A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1360. Formula I.19 wherein R¹ is Y-5B, R² is H, R⁹ is H and R¹⁰ is H. Table 1361. Formula I.19 wherein R¹ is Y-5B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1362. Formula I.19 wherein R¹ is Y-5B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1363. Formula I.19 wherein R¹ is Y-6A, R² is H, R⁹ is H and R¹⁰ is H. Table 1364. Formula I.19 wherein R¹ is Y-6A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1365. Formula I.19 wherein R¹ is Y-6A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1366. Formula I.19 wherein R¹ is Y-6B, R² is H, R⁹ is H and R¹⁰ is H. Table 1367. Formula I.19 wherein R¹ is Y-6B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1368. Formula I.19 wherein R¹ is Y-6B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1369. Formula I.19 wherein R¹ is Y-7A, R² is H, R⁹ is H and R¹⁰ is H. Table 1370. Formula I.19 wherein R¹ is Y-7A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1371. Formula I.19 wherein R¹ is Y-7A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1372. Formula I.19 wherein R¹ is Y-7B, R² is H, R⁹ is H and R¹⁰ is H. Table 1373. Formula I.19 wherein R¹ is Y-7B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1374. Formula I.19 wherein R¹ is Y-7B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1375. Formula I.19 wherein R¹ is Y-8A, R² is H, R⁹ is H and R¹⁰ is H. Table 1376. Formula I.19 wherein R¹ is Y-8A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1377. Formula I.19 wherein R¹ is Y-8A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1378. Formula I.19 wherein R¹ is Y-8B, R² is H, R⁹ is H and R¹⁰ is H. Table 1379. Formula I.19 wherein R¹ is Y-8B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1380. Formula I.19 wherein R¹ is Y-8B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1381. Formula I.19 wherein R¹ is Y-1A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1382. Formula I.19 wherein R¹ is Y-1A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1383. Formula I.19 wherein R¹ is Y-1A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1384. Formula I.19 wherein R¹ is Y-1B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1385. Formula I.19 wherein R¹ is Y-1B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1386. Formula I.19 wherein R¹ is Y-1B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1387. Formula I.19 wherein R¹ is Y-2A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1388. Formula I.19 wherein R¹ is Y-2A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1389. Formula I.19 wherein R¹ is Y-2A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1390. Formula I.19 wherein R¹ is Y-2B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1391. Formula I.19 wherein R¹ is Y-2B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1392. Formula I.19 wherein R¹ is Y-2B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1393. Formula I.19 wherein R¹ is Y-3A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1394. Formula I.19 wherein R¹ is Y-3A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1395. Formula I.19 wherein R¹ is Y-3A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1396. Formula I.19 wherein R¹ is Y-3B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1397. Formula I.19 wherein R¹ is Y-3B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1398. Formula I.19 wherein R¹ is Y-3B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1399. Formula I.19 wherein R¹ is Y-3C, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1400. Formula I.19 wherein R¹ is Y-3C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1401. Formula I.19 wherein R¹ is Y-3C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1402. Formula I.19 wherein R¹ is Y-3D, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1403. Formula I.19 wherein R¹ is Y-3D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1404. Formula I.19 wherein R¹ is Y-3D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1405. Formula I.19 wherein R¹ is Y-4A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1406. Formula I.19 wherein R¹ is Y-4A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1407. Formula I.19 wherein R¹ is Y-4A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1408. Formula I.19 wherein R¹ is Y-4B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1409. Formula I.19 wherein R¹ is Y-4B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1410. Formula I.19 wherein R¹ is Y-4B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1411. Formula I.19 wherein R¹ is Y-4C, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1412. Formula I.19 wherein R¹ is Y-4C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1413. Formula I.19 wherein R¹ is Y-4C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1414. Formula I.19 wherein R¹ is Y-4D, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1415. Formula I.19 wherein R¹ is Y-4D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1416. Formula I.19 wherein R¹ is Y-4D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1417. Formula I.19 wherein R¹ is Y-5A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1418. Formula I.19 wherein R¹ is Y-5A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1419. Formula I.19 wherein R¹ is Y-5A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1420. Formula I.19 wherein R¹ is Y-5B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1421. Formula I.19 wherein R¹ is Y-5B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1422. Formula I.19 wherein R¹ is Y-5B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1423. Formula I.19 wherein R¹ is Y-6A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1424. Formula I.19 wherein R¹ is Y-6A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1425. Formula I.19 wherein R¹ is Y-6A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1426. Formula I.19 wherein R¹ is Y-6B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1427. Formula I.19 wherein R¹ is Y-6B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1428. Formula I.19 wherein R¹ is Y-6B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1429. Formula I.19 wherein R¹ is Y-7A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1430. Formula I.19 wherein R¹ is Y-7A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1431. Formula I.19 wherein R¹ is Y-7A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1432. Formula I.19 wherein R¹ is Y-7B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1433. Formula I.19 wherein R¹ is Y-7B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1434. Formula I.19 wherein R¹ is Y-7B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1435. Formula I.19 wherein R¹ is Y-8A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1436. Formula I.19 wherein R¹ is Y-8A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1437. Formula I.19 wherein R¹ is Y-8A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1438. Formula I.19 wherein R¹ is Y-8B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1439. Formula I.19 wherein R¹ is Y-8B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1440. Formula I.19 wherein R¹ is Y-8B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1441. Formula I.19 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1442. Formula I.19 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1443. Formula I.19 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1444. Formula I.19 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1445. Formula I.19 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1446. Formula I.19 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1447. Formula I.19 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1448. Formula I.19 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1449. Formula I.19 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1450. Formula I.19 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1451. Formula I.19 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1452. Formula I.19 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1453. Formula I.19 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1454. Formula I.19 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1455. Formula I.19 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1456. Formula I.19 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1457. Formula I.19 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1458. Formula I.19 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1459. Formula I.19 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1460. Formula I.19 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1461. Formula I.19 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1462. Formula I.19 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1463. Formula I.19 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1464. Formula I.19 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1465. Formula I.19 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1466. Formula I.19 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1467. Formula I.19 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1468. Formula I.19 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1469. Formula I.19 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1470. Formula I.19 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1471. Formula I.19 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1472. Formula I.19 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1473. Formula I.19 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1474. Formula I.19 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1475. Formula I.19 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1476. Formula I.19 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1477. Formula I.19 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1478. Formula I.19 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1479. Formula I.19 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1480. Formula I.19 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1481. Formula I.19 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1482. Formula I.19 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1483. Formula I.19 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1484. Formula I.19 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1485. Formula I.19 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1486. Formula I.19 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1487. Formula I.19 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1488. Formula I.19 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1489. Formula I.19 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1490. Formula I.19 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1491. Formula I.19 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1492. Formula I.19 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1493. Formula I.19 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1494. Formula I.19 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1495. Formula I.19 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1496. Formula I.19 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1497. Formula I.19 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1498. Formula I.19 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1499. Formula I.19 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1500. Formula I.19 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1501. Formula I.19 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1502. Formula I.19 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1503. Formula I.19 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1504. Formula I.19 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1505. Formula I.19 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is CH₃, R¹⁰ is H. Table 1506. Formula I.19 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1507. Formula I.19 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1508. Formula I.19 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1509. Formula I.19 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1510. Formula I.19 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1511. Formula I.19 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1512. Formula I.19 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1513. Formula I.19 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1514. Formula I.19 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1515. Formula I.19 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1516. Formula I.19 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1517. Formula I.19 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1518. Formula I.19 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1519. Formula I.19 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1520. Formula I.19 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1521. Formula I.19 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1522. Formula I.19 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1523. Formula I.19 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1524. Formula I.19 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1525. Formula I.19 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1526. Formula I.19 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1527. Formula I.19 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1528. Formula I.19 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1529. Formula I.19 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1530. Formula I.19 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1531. Formula I.19 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1532. Formula I.19 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1533. Formula I.19 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1534. Formula I.19 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1535. Formula I.19 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1536. Formula I.19 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1537. Formula I.19 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1538. Formula I.19 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1539. Formula I.19 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1540. Formula I.19 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1541. Formula I.19 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1542. Formula I.19 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1543. Formula I.19 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1544. Formula I.19 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1545. Formula I.19 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1546. Formula I.19 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1547. Formula I.19 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1548. Formula I.19 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1549. Formula I.19 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1550. Formula I.19 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1551. Formula I.19 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1552. Formula I.19 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1553. Formula I.19 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1554. Formula I.19 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1555. Formula I.19 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1556. Formula I.19 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1557. Formula I.19 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1558. Formula I.19 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1559. Formula I.19 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1560. Formula I.19 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1561. Formula I.20 wherein R¹ is Y-1A, R² is H, R⁹ is H and R¹⁰ is H. Table 1562. Formula I.20 wherein R¹ is Y-1A, R² is H, R⁹ is CH₃ and, R¹⁰ is H. Table 1563. Formula I.20 wherein R¹ is Y-1A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1564. Formula I.20 wherein R¹ is Y-1B, R² is H, R⁹ is H and R¹⁰ is H. Table 1565. Formula I.20 wherein R¹ is Y-1B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1566. Formula I.20 wherein R¹ is Y-1B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1567. Formula I.20 wherein R¹ is Y-2A, R² is H, R⁹ is H and R¹⁰ is H. Table 1568. Formula I.20 wherein R¹ is Y-2A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1569. Formula I.20 wherein R¹ is Y-2A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1570. Formula I.20 wherein R¹ is Y-2B, R² is H, R⁹ is H and R¹⁰ is H. Table 1571. Formula I.20 wherein R¹ is Y-2B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1572. Formula I.20 wherein R¹ is Y-2B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1573. Formula I.20 wherein R¹ is Y-3A, R² is H, R⁹ is H and R¹⁰ is H. Table 1574. Formula I.20 wherein R¹ is Y-3A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1575. Formula I.20 wherein R¹ is Y-3A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1576. Formula I.20 wherein R¹ is Y-3B, R² is H, R⁹ is H and R¹⁰ is H. Table 1577. Formula I.20 wherein R¹ is Y-3B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1578. Formula I.20 wherein R¹ is Y-3B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1579. Formula I.20 wherein R¹ is Y-3C, R² is H, R⁹ is H and R¹⁰ is H. Table 1580. Formula I.20 wherein R¹ is Y-3C, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1581. Formula I.20 wherein R¹ is Y-3C, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1582. Formula I.20 wherein R¹ is Y-3D, R² is H, R⁹ is H and R¹⁰ is H. Table 1583. Formula I.20 wherein R¹ is Y-3D, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1584. Formula I.20 wherein R¹ is Y-3D, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1585. Formula I.20 wherein R¹ is Y-4A, R² is H, R⁹ is H and R¹⁰ is H. Table 1586. Formula I.20 wherein R¹ is Y-4A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1587. Formula I.20 wherein R¹ is Y-4A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1588. Formula I.20 wherein R¹ is Y-4B, R² is H, R⁹ is H and R¹⁰ is H. Table 1589. Formula I.20 wherein R¹ is Y-4B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1590. Formula I.20 wherein R¹ is Y-4B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1591. Formula I.20 wherein R¹ is Y-4C, R² is H, R⁹ is H and R¹⁰ is H. Table 1592. Formula I.20 wherein R¹ is Y-4C, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1593. Formula I.20 wherein R¹ is Y-4C, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1594. Formula I.20 wherein R¹ is Y-4D, R² is H, R⁹ is H and R¹⁰ is H. Table 1595. Formula I.20 wherein R¹ is Y-4D, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1596. Formula I.20 wherein R¹ is Y-4D, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1597. Formula I.20 wherein R¹ is Y-5A, R² is H, R⁹ is H and R¹⁰ is H. Table 1598. Formula I.20 wherein R¹ is Y-5A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1599. Formula I.20 wherein R¹ is Y-5A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1600. Formula I.20 wherein R¹ is Y-5B, R² is H, R⁹ is H and R¹⁰ is H. Table 1601. Formula I.20 wherein R¹ is Y-5B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1602. Formula I.20 wherein R¹ is Y-5B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1603. Formula I.20 wherein R¹ is Y-6A, R² is H, R⁹ is H and R¹⁰ is H. Table 1604. Formula I.20 wherein R¹ is Y-6A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1605. Formula I.20 wherein R¹ is Y-6A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1606. Formula I.20 wherein R¹ is Y-6B, R² is H, R⁹ is H and R¹⁰ is H. Table 1607. Formula I.20 wherein R¹ is Y-6B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1608. Formula I.20 wherein R¹ is Y-6B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1609. Formula I.20 wherein R¹ is Y-7A, R² is H, R⁹ is H and R¹⁰ is H. Table 1610. Formula I.20 wherein R¹ is Y-7A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1611. Formula I.20 wherein R¹ is Y-7A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1612. Formula I.20 wherein R¹ is Y-7B, R² is H, R⁹ is H and R¹⁰ is H. Table 1613. Formula I.20 wherein R¹ is Y-7B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1614. Formula I.20 wherein R¹ is Y-7B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1615. Formula I.20 wherein R¹ is Y-8A, R² is H, R⁹ is H and R¹⁰ is H. Table 1616. Formula I.20 wherein R¹ is Y-8A, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1617. Formula I.20 wherein R¹ is Y-8A, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1618. Formula I.20 wherein R¹ is Y-8B, R² is H, R⁹ is H and R¹⁰ is H. Table 1619. Formula I.20 wherein R¹ is Y-8B, R² is H, R⁹ is CH₃ and R¹⁰ is H. Table 1620. Formula I.20 wherein R¹ is Y-8B, R² is H, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1621. Formula I.20 wherein R¹ is Y-1A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1622. Formula I.20 wherein R¹ is Y-1A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1623. Formula I.20 wherein R¹ is Y-1A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1624. Formula I.20 wherein R¹ is Y-1B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1625. Formula I.20 wherein R¹ is Y-1B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1626. Formula I.20 wherein R¹ is Y-1B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1627. Formula I.20 wherein R¹ is Y-2A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1628. Formula I.20 wherein R¹ is Y-2A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1629. Formula I.20 wherein R¹ is Y-2A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1630. Formula I.20 wherein R¹ is Y-2B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1631. Formula I.20 wherein R¹ is Y-2B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1632. Formula I.20 wherein R¹ is Y-2B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1633. Formula I.20 wherein R¹ is Y-3A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1634. Formula I.20 wherein R¹ is Y-3A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1635. Formula I.20 wherein R¹ is Y-3A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1636. Formula I.20 wherein R¹ is Y-3B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1637. Formula I.20 wherein R¹ is Y-3B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1638. Formula I.20 wherein R¹ is Y-3B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1639. Formula I.20 wherein R¹ is Y-3C, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1640. Formula I.20 wherein R¹ is Y-3C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1641. Formula I.20 wherein R¹ is Y-3C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1642. Formula I.20 wherein R¹ is Y-3D, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1643. Formula I.20 wherein R¹ is Y-3D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1644. Formula I.20 wherein R¹ is Y-3D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1645. Formula I.20 wherein R¹ is Y-4A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1646. Formula I.20 wherein R¹ is Y-4A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1647. Formula I.20 wherein R¹ is Y-4A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1648. Formula I.20 wherein R¹ is Y-4B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1649. Formula I.20 wherein R¹ is Y-4B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1650. Formula I.20 wherein R¹ is Y-4B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1651. Formula I.20 wherein R¹ is Y-4C, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1652. Formula I.20 wherein R¹ is Y-4C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1653. Formula I.20 wherein R¹ is Y-4C, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1654. Formula I.20 wherein R¹ is Y-4D, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1655. Formula I.20 wherein R¹ is Y-4D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1656. Formula I.20 wherein R¹ is Y-4D, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1657. Formula I.20 wherein R¹ is Y-5A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1658. Formula I.20 wherein R¹ is Y-5A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1659. Formula I.20 wherein R¹ is Y-5A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1660. Formula I.20 wherein R¹ is Y-5B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1661. Formula I.20 wherein R¹ is Y-5B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1662. Formula I.20 wherein R¹ is Y-5B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1663. Formula I.20 wherein R¹ is Y-6A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1664. Formula I.20 wherein R¹ is Y-6A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1665. Formula I.20 wherein R¹ is Y-6A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1666. Formula I.20 wherein R¹ is Y-6B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1667. Formula I.20 wherein R¹ is Y-6B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1668. Formula I.20 wherein R¹ is Y-6B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1669. Formula I.20 wherein R¹ is Y-7A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1670. Formula I.20 wherein R¹ is Y-7A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1671. Formula I.20 wherein R¹ is Y-7A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1672. Formula I.20 wherein R¹ is Y-7B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1673. Formula I.20 wherein R¹ is Y-7B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1674. Formula I.20 wherein R¹ is Y-7B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1675. Formula I.20 wherein R¹ is Y-8A, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1676. Formula I.20 wherein R¹ is Y-8A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1677. Formula I.20 wherein R¹ is Y-8A, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1678. Formula I.20 wherein R¹ is Y-8B, R² is CH₃, R⁹ is H and R¹⁰ is H. Table 1679. Formula I.20 wherein R¹ is Y-8B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is H. Table 1680. Formula I.20 wherein R¹ is Y-8B, R² is CH₃, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1681. Formula I.20 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1682. Formula I.20 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1683. Formula I.20 wherein R¹ is Y-1A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1684. Formula I.20 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1685. Formula I.20 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1686. Formula I.20 wherein R¹ is Y-1B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1687. Formula I.20 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1688. Formula I.20 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1689. Formula I.20 wherein R¹ is Y-2A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1690. Formula I.20 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1691. Formula I.20 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1692. Formula I.20 wherein R¹ is Y-2B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1693. Formula I.20 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1694. Formula I.20 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1695. Formula I.20 wherein R¹ is Y-3A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1696. Formula I.20 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1697. Formula I.20 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1698. Formula I.20 wherein R¹ is Y-3B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1699. Formula I.20 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1700. Formula I.20 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1701. Formula I.20 wherein R¹ is Y-3C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1702. Formula I.20 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1703. Formula I.20 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1704. Formula I.20 wherein R¹ is Y-3D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1705. Formula I.20 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1706. Formula I.20 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1707. Formula I.20 wherein R¹ is Y-4A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1708. Formula I.20 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1709. Formula I.20 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1710. Formula I.20 wherein R¹ is Y-4B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1711. Formula I.20 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1712. Formula I.20 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1713. Formula I.20 wherein R¹ is Y-4C, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1714. Formula I.20 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1715. Formula I.20 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1716. Formula I.20 wherein R¹ is Y-4D, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1717. Formula I.20 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1718. Formula I.20 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1719. Formula I.20 wherein R¹ is Y-5A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1720. Formula I.20 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1721. Formula I.20 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1722. Formula I.20 wherein R¹ is Y-5B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1723. Formula I.20 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1724. Formula I.20 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1725. Formula I.20 wherein R¹ is Y-6A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1726. Formula I.20 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1727. Formula I.20 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1728. Formula I.20 wherein R¹ is Y-6B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1729. Formula I.20 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1730. Formula I.20 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1731. Formula I.20 wherein R¹ is Y-7A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1732. Formula I.20 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1733. Formula I.20 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1734. Formula I.20 wherein R¹ is Y-7B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1735. Formula I.20 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1736. Formula I.20 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1737. Formula I.20 wherein R¹ is Y-8A, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1738. Formula I.20 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is H and R¹⁰ is H. Table 1739. Formula I.20 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1740. Formula I.20 wherein R¹ is Y-8B, R² is C₂H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1741. Formula I.20 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1742. Formula I.20 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1743. Formula I.20 wherein R¹ is Y-1A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1744. Formula I.20 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1745. Formula I.20 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is CH₃, R¹⁰ is H. Table 1746. Formula I.20 wherein R¹ is Y-1B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1747. Formula I.20 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1748. Formula I.20 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1749. Formula I.20 wherein R¹ is Y-2A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1750. Formula I.20 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1751. Formula I.20 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1752. Formula I.20 wherein R¹ is Y-2B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1753. Formula I.20 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1754. Formula I.20 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1755. Formula I.20 wherein R¹ is Y-3A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1756. Formula I.20 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1757. Formula I.20 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1758. Formula I.20 wherein R¹ is Y-3B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1759. Formula I.20 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1760. Formula I.20 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1761. Formula I.20 wherein R¹ is Y-3C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1762. Formula I.20 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1763. Formula I.20 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1764. Formula I.20 wherein R¹ is Y-3D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1765. Formula I.20 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1766. Formula I.20 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1767. Formula I.20 wherein R¹ is Y-4A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1768. Formula I.20 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1769. Formula I.20 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1770. Formula I.20 wherein R¹ is Y-4B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1771. Formula I.20 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1772. Formula I.20 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1773. Formula I.20 wherein R¹ is Y-4C, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1774. Formula I.20 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1775. Formula I.20 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1776. Formula I.20 wherein R¹ is Y-4D, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1777. Formula I.20 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1778. Formula I.20 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1779. Formula I.20 wherein R¹ is Y-5A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1780. Formula I.20 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1781. Formula I.20 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1782. Formula I.20 wherein R¹ is Y-5B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1783. Formula I.20 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1784. Formula I.20 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1785. Formula I.20 wherein R¹ is Y-6A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1786. Formula I.20 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1787. Formula I.20 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1788. Formula I.20 wherein R¹ is Y-6B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1789. Formula I.20 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1790. Formula I.20 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1791. Formula I.20 wherein R¹ is Y-7A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1792. Formula I.20 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1793. Formula I.20 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1794. Formula I.20 wherein R¹ is Y-7B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1795. Formula I.20 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1796. Formula I.20 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1797. Formula I.20 wherein R¹ is Y-8A, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1798. Formula I.20 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is H and R¹⁰ is H. Table 1799. Formula I.20 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is H. Table 1800. Formula I.20 wherein R¹ is Y-8B, R² is c-C₃H₅, R⁹ is CH₃ and R¹⁰ is CH₃. Table 1801. Formula I.25 wherein R¹ is Y-1A and R² is H. Table 1802. Formula I.25 wherein R¹ is Y-1B and R² is H. Table 1803. Formula I.25 wherein R¹ is Y-2A and R² is H. Table 1804. Formula I.25 wherein R¹ is Y-2B and R² is H. Table 1805. Formula I.25 wherein R¹ is Y-3A and R² is H. Table 1806. Formula I.25 wherein R¹ is Y-3B and R² is H. Table 1807. Formula I.25 wherein R¹ is Y-3C and R² is H. Table 1808. Formula I.25 wherein R¹ is Y-3D and R² is H. Table 1809. Formula I.25 wherein R¹ is Y-4A and R² is H. Table 1810. Formula I.25 wherein R¹ is Y-4B and R² is H. Table 1811. Formula I.25 wherein R¹ is Y-4C and R² is H. Table 1812. Formula I.25 wherein R¹ is Y-4D and R² is H. Table 1813. Formula I.25 wherein R¹ is Y-5A and R² is H. Table 1814. Formula I.25 wherein R¹ is Y-5B and R² is H. Table 1815. Formula I.25 wherein R¹ is Y-6A and R² is H. Table 1816. Formula I.25 wherein R¹ is Y-6B and R² is H. Table 1817. Formula I.25 wherein R¹ is Y-7A and R² is H. Table 1818. Formula I.25 wherein R¹ is Y-7B and R² is H. Table 1819. Formula I.25 wherein R¹ is Y-8A and R² is H. Table 1820. Formula I.25 wherein R¹ is Y-8B and R² is H. Table 1821. Formula I.25 wherein R¹ is Y-1A and R² is CH₃. Table 1822. Formula I.25 wherein R¹ is Y-1B and R² is CH₃. Table 1823. Formula I.25 wherein R¹ is Y-2A and R² is CH₃. Table 1824. Formula I.25 wherein R¹ is Y-2B and R² is CH₃. Table 1825. Formula I.25 wherein R¹ is Y-3A and R² is CH₃. Table 1826. Formula I.25 wherein R¹ is Y-3B and R² is CH₃. Table 1827. Formula I.25 wherein R¹ is Y-3C and R² is CH₃. Table 1828. Formula I.25 wherein R¹ is Y-3D and R² is CH₃. Table 1829. Formula I.25 wherein R¹ is Y-4A and R² is CH₃. Table 1830. Formula I.25 wherein R¹ is Y-4B and R² is CH₃. Table 1831. Formula I.25 wherein R¹ is Y-4C and R² is CH₃. Table 1832. Formula I.25 wherein R¹ is Y-4D and R² is CH₃. Table 1833. Formula I.25 wherein R¹ is Y-5A and R² is CH₃. Table 1834. Formula I.25 wherein R¹ is Y-5B and R² is CH₃. Table 1835. Formula I.25 wherein R¹ is Y-6A and R² is CH₃. Table 1836. Formula I.25 wherein R¹ is Y-6B and R² is CH₃. Table 1837. Formula I.25 wherein R¹ is Y-7A and R² is CH₃. Table 1838. Formula I.25 wherein R¹ is Y-7B and R² is CH₃. Table 1839. Formula I.25 wherein R¹ is Y-8A and R² is CH₃. Table 1840. Formula I.25 wherein R¹ is Y-8B and R² is CH₃. Table 1841. Formula I.25 wherein R¹ is Y-1A and R² is c-C₃H₅. Table 1842. Formula I.25 wherein R¹ is Y-1B and R² is c-C₃H₅. Table 1843. Formula I.25 wherein R¹ is Y-2A and R² is c-C₃H₅. Table 1844. Formula I.25 wherein R¹ is Y-2B and R² is c-C₃H₅. Table 1845. Formula I.25 wherein R¹ is Y-3A and R² is c-C₃H₅. Table 1846. Formula I.25 wherein R¹ is Y-3B and R² is c-C₃H₅. Table 1847. Formula I.25 wherein R¹ is Y-3C and R² is c-C₃H₅. Table 1848. Formula I.25 wherein R¹ is Y-3D and R² is c-C₃H₅. Table 1849. Formula I.25 wherein R¹ is Y-4A and R² is c-C₃H₅. Table 1850. Formula I.25 wherein R¹ is Y-4B and R² is c-C₃H₅. Table 1851. Formula I.25 wherein R¹ is Y-4C and R² is c-C₃H₅. Table 1852. Formula I.25 wherein R¹ is Y-4D and R² is c-C₃H₅. Table 1853. Formula I.25 wherein R¹ is Y-5A and R² is c-C₃H₅. Table 1854. Formula I.25 wherein R¹ is Y-5B and R² is c-C₃H₅. Table 1855. Formula I.25 wherein R¹ is Y-6A and R² is c-C₃H₅. Table 1856. Formula I.25 wherein R¹ is Y-6B and R² is c-C₃H₅. Table 1857. Formula I.25 wherein R¹ is Y-7A and R² is c-C₃H₅. Table 1858. Formula I.25 wherein R¹ is Y-7B and R² is c-C₃H₅. Table 1859. Formula I.25 wherein R¹ is Y-8A and R² is c-C₃H₅. Table 1860. Formula I.25 wherein R¹ is Y-8B and R² is c-C₃H₅. Table 1861. Formula I.26 wherein R¹ is Y-1A and R² is H. Table 1862. Formula I.26 wherein R¹ is Y-1B and R² is H. Table 1863. Formula I.26 wherein R¹ is Y-2A and R² is H. Table 1864. Formula I.26 wherein R¹ is Y-2B and R² is H. Table 1865. Formula I.26 wherein R¹ is Y-3A and R² is H. Table 1866. Formula I.26 wherein R¹ is Y-3B and R² is H. Table 1867. Formula I.26 wherein R¹ is Y-3C and R² is H. Table 1868. Formula I.26 wherein R¹ is Y-3D and R² is H. Table 1869. Formula I.26 wherein R¹ is Y-4A and R² is H. Table 1870. Formula I.26 wherein R¹ is Y-4B and R² is H. Table 1871. Formula I.26 wherein R¹ is Y-4C and R² is H. Table 1872. Formula I.26 wherein R¹ is Y-4D and R² is H. Table 1873. Formula I.26 wherein R¹ is Y-5A and R² is H. Table 1874. Formula I.26 wherein R¹ is Y-5B and R² is H. Table 1875. Formula I.26 wherein R¹ is Y-6A and R² is H. Table 1876. Formula I.26 wherein R¹ is Y-6B and R² is H. Table 1877. Formula I.26 wherein R¹ is Y-7A and R² is H. Table 1878. Formula I.26 wherein R¹ is Y-7B and R² is H. Table 1879. Formula I.26 wherein R¹ is Y-8A and R² is H. Table 1880. Formula I.26 wherein R¹ is Y-8B and R² is H. Table 1881. Formula I.26 wherein R¹ is Y-1A and R² is CH₃. Table 1882. Formula I.26 wherein R¹ is Y-1B and R² is CH₃. Table 1883. Formula I.26 wherein R¹ is Y-2A and R² is CH₃. Table 1884. Formula I.26 wherein R¹ is Y-2B and R² is CH₃. Table 1885. Formula I.26 wherein R¹ is Y-3A and R² is CH₃. Table 1886. Formula I.26 wherein R¹ is Y-3B and R² is CH₃. Table 1887. Formula I.26 wherein R¹ is Y-3C and R² is CH₃. Table 1888. Formula I.26 wherein R¹ is Y-3D and R² is CH₃. Table 1889. Formula I.26 wherein R¹ is Y-4A and R² is CH₃. Table 1890. Formula I.26 wherein R¹ is Y-4B and R² is CH₃. Table 1891. Formula I.26 wherein R¹ is Y-4C and R² is CH₃. Table 1892. Formula I.26 wherein R¹ is Y-4D and R² is CH₃. Table 1893. Formula I.26 wherein R¹ is Y-5A and R² is CH₃. Table 1894. Formula I.26 wherein R¹ is Y-5B and R² is CH₃. Table 1895. Formula I.26 wherein R¹ is Y-6A and R² is CH₃. Table 1896. Formula I.26 wherein R¹ is Y-6B and R² is CH₃. Table 1897. Formula I.26 wherein R¹ is Y-7A and R² is CH₃. Table 1898. Formula I.26 wherein R¹ is Y-7B and R² is CH₃. Table 1899. Formula I.26 wherein R¹ is Y-8A and R² is CH₃. Table 1900. Formula I.26 wherein R¹ is Y-8B and R² is CH₃. Table 1901. Formula I.26 wherein R¹ is Y-1A and R² is c-C₃H₅. Table 1902. Formula I.26 wherein R¹ is Y-1B and R² is c-C₃H₅. Table 1903. Formula I.26 wherein R¹ is Y-2A and R² is c-C₃H₅. Table 1904. Formula I.26 wherein R¹ is Y-2B and R² is c-C₃H₅. Table 1905. Formula I.26 wherein R¹ is Y-3A and R² is c-C₃H₅. Table 1906. Formula I.26 wherein R¹ is Y-3B and R² is c-C₃H₅. Table 1907. Formula I.26 wherein R¹ is Y-3C and R² is c-C₃H₅. Table 1908. Formula I.26 wherein R¹ is Y-3D and R² is c-C₃H₅. Table 1909. Formula I.26 wherein R¹ is Y-4A and R² is c-C₃H₅. Table 1910. Formula I.26 wherein R¹ is Y-4B and R² is c-C₃H₅. Table 1911. Formula I.26 wherein R¹ is Y-4C and R² is c-C₃H₅. Table 1912. Formula I.26 wherein R¹ is Y-4D and R² is c-C₃H₅. Table 1913. Formula I.26 wherein R¹ is Y-5A and R² is c-C₃H₅. Table 1914. Formula I.26 wherein R¹ is Y-5B and R² is c-C₃H₅. Table 1915. Formula I.26 wherein R¹ is Y-6A and R² is c-C₃H₅. Table 1916. Formula I.26 wherein R¹ is Y-6B and R² is c-C₃H₅. Table 1917. Formula I.26 wherein R¹ is Y-7A and R² is c-C₃H₅. Table 1918. Formula I.26 wherein R¹ is Y-7B and R² is c-C₃H₅. Table 1919. Formula I.26 wherein R¹ is Y-8A and R² is c-C₃H₅. Table 1920. Formula I.26 wherein R¹ is Y-8B and R² is c-C₃H₅. Table 1921. Formula I.29 wherein R¹ is Y-1A and R² is H. Table 1922. Formula I.29 wherein R¹ is Y-1B and R² is H. Table 1923. Formula I.29 wherein R¹ is Y-2A and R² is H. Table 1924. Formula I.29 wherein R¹ is Y-2B and R² is H. Table 1925. Formula I.29 wherein R¹ is Y-3A and R² is H. Table 1926. Formula I.29 wherein R¹ is Y-3B and R² is H. Table 1927. Formula I.29 wherein R¹ is Y-3C and R² is H. Table 1928. Formula I.29 wherein R¹ is Y-3D and R² is H. Table 1929. Formula I.29 wherein R¹ is Y-4A and R² is H. Table 1930. Formula I.29 wherein R¹ is Y-4B and R² is H. Table 1931. Formula I.29 wherein R¹ is Y-4C and R² is H. Table 1932. Formula I.29 wherein R¹ is Y-4D and R² is H. Table 1933. Formula I.29 wherein R¹ is Y-5A and R² is H. Table 1934. Formula I.29 wherein R¹ is Y-5B and R² is H. Table 1935. Formula I.29 wherein R¹ is Y-6A and R² is H. Table 1936. Formula I.29 wherein R¹ is Y-6B and R² is H. Table 1937. Formula I.29 wherein R¹ is Y-7A and R² is H. Table 1938. Formula I.29 wherein R¹ is Y-7B and R² is H. Table 1939. Formula I.29 wherein R¹ is Y-8A and R² is H. Table 1940. Formula I.29 wherein R¹ is Y-8B and R² is H. Table 1941. Formula I.29 wherein R¹ is Y-1A and R² is CH₃. Table 1942. Formula I.29 wherein R¹ is Y-1B and R² is CH₃. Table 1943. Formula I.29 wherein R¹ is Y-2A and R² is CH₃. Table 1944. Formula I.29 wherein R¹ is Y-2B and R² is CH₃. Table 1945. Formula I.29 wherein R¹ is Y-3A and R² is CH₃. Table 1946. Formula I.29 wherein R¹ is Y-3B and R² is CH₃. Table 1947. Formula I.29 wherein R¹ is Y-3C and R² is CH₃. Table 1948. Formula I.29 wherein R¹ is Y-3D and R² is CH₃. Table 1949. Formula I.29 wherein R¹ is Y-4A and R² is CH₃. Table 1950. Formula I.29 wherein R¹ is Y-4B and R² is CH₃. Table 1951. Formula I.29 wherein R¹ is Y-4C and R² is CH₃. Table 1952. Formula I.29 wherein R¹ is Y-4D and R² is CH₃. Table 1953. Formula I.29 wherein R¹ is Y-5A and R² is CH₃. Table 1954. Formula I.29 wherein R¹ is Y-5B and R² is CH₃. Table 1955. Formula I.29 wherein R¹ is Y-6A and R² is CH₃. Table 1956. Formula I.29 wherein R¹ is Y-6B and R² is CH₃. Table 1957. Formula I.29 wherein R¹ is Y-7A and R² is CH₃. Table 1958. Formula I.29 wherein R¹ is Y-7B and R² is CH₃. Table 1959. Formula I.29 wherein R¹ is Y-8A and R² is CH₃. Table 1960. Formula I.29 wherein R¹ is Y-8B and R² is CH₃. Table 1961. Formula I.29 wherein R¹ is Y-1A and R² is c-C₃H₅. Table 1962. Formula I.29 wherein R¹ is Y-1B and R² is c-C₃H₅. Table 1963. Formula I.29 wherein R¹ is Y-2A and R² is c-C₃H₅. Table 1964. Formula I.29 wherein R¹ is Y-2B and R² is c-C₃H₅. Table 1965. Formula I.29 wherein R¹ is Y-3A and R² is c-C₃H₅. Table 1966. Formula I.29 wherein R¹ is Y-3B and R² is c-C₃H₅. Table 1967. Formula I.29 wherein R¹ is Y-3C and R² is c-C₃H₅. Table 1968. Formula I.29 wherein R¹ is Y-3D and R² is c-C₃H₅. Table 1969. Formula I.29 wherein R¹ is Y-4A and R² is c-C₃H₅. Table 1970. Formula I.29 wherein R¹ is Y-4B and R² is c-C₃H₅. Table 1971. Formula I.29 wherein R¹ is Y-4C and R² is c-C₃H₅. Table 1972. Formula I.29 wherein R¹ is Y-4D and R² is c-C₃H₅. Table 1973. Formula I.29 wherein R¹ is Y-5A and R² is c-C₃H₅. Table 1974. Formula I.29 wherein R¹ is Y-5B and R² is c-C₃H₅. Table 1975. Formula I.29 wherein R¹ is Y-6A and R² is c-C₃H₅. Table 1976. Formula I.29 wherein R¹ is Y-6B and R² is c-C₃H₅. Table 1977. Formula I.29 wherein R¹ is Y-7A and R² is c-C₃H₅. Table 1978. Formula I.29 wherein R¹ is Y-7B and R² is c-C₃H₅. Table 1979. Formula I.29 wherein R¹ is Y-8A and R² is c-C₃H₅. Table 1980. Formula I.29 wherein R¹ is Y-8B and R² is c-C₃H₅. Table 1981. Formula I.30 wherein R¹ is Y-1A and R² is H. Table 1982. Formula I.30 wherein R¹ is Y-1B and R² is H. Table 1983. Formula I.30 wherein R¹ is Y-2A and R² is H. Table 1984. Formula I.30 wherein R¹ is Y-2B and R² is H. Table 1985. Formula I.30 wherein R¹ is Y-3A and R² is H. Table 1986. Formula I.30 wherein R¹ is Y-3B and R² is H. Table 1987. Formula I.30 wherein R¹ is Y-3C and R² is H. Table 1988. Formula I.30 wherein R¹ is Y-3D and R² is H. Table 1989. Formula I.30 wherein R¹ is Y-4A and R² is H. Table 1990. Formula I.30 wherein R¹ is Y-4B and R² is H. Table 1991. Formula I.30 wherein R¹ is Y-4C and R² is H. Table 1992. Formula I.30 wherein R¹ is Y-4D and R² is H. Table 1993. Formula I.30 wherein R¹ is Y-5A and R² is H. Table 1994. Formula I.30 wherein R¹ is Y-5B and R² is H. Table 1995. Formula I.30 wherein R¹ is Y-6A and R² is H. Table 1996. Formula I.30 wherein R¹ is Y-6B and R² is H. Table 1997. Formula I.30 wherein R¹ is Y-7A and R² is H. Table 1998. Formula I.30 wherein R¹ is Y-7B and R² is H. Table 1999. Formula I.30 wherein R¹ is Y-8A and R² is H. Table 2000. Formula I.30 wherein R¹ is Y-8B and R² is H. Table 2001. Formula I.30 wherein R¹ is Y-1A and R² is CH₃. Table 2002. Formula I.30 wherein R¹ is Y-1B and R² is CH₃. Table 2003. Formula I.30 wherein R¹ is Y-2A and R² is CH₃. Table 2004. Formula I.30 wherein R¹ is Y-2B and R² is CH₃. Table 2005. Formula I.30 wherein R¹ is Y-3A and R² is CH₃. Table 2006. Formula I.30 wherein R¹ is Y-3B and R² is CH₃. Table 2007. Formula I.30 wherein R¹ is Y-3C and R² is CH₃. Table 2008. Formula I.30 wherein R¹ is Y-3D and R² is CH₃. Table 2009. Formula I.30 wherein R¹ is Y-4A and R² is CH₃. Table 2010. Formula I.30 wherein R¹ is Y-4B and R² is CH₃. Table 2011. Formula I.30 wherein R¹ is Y-4C and R² is CH₃. Table 2012. Formula I.30 wherein R¹ is Y-4D and R² is CH₃. Table 2013. Formula I.30 wherein R¹ is Y-5A and R² is CH₃. Table 2014. Formula I.30 wherein R¹ is Y-5B and R² is CH₃. Table 2015. Formula I.30 wherein R¹ is Y-6A and R² is CH₃. Table 2016. Formula I.30 wherein R¹ is Y-6B and R² is CH₃. Table 2017. Formula I.30 wherein R¹ is Y-7A and R² is CH₃. Table 2018. Formula I.30 wherein R¹ is Y-7B and R² is CH₃. Table 2019. Formula I.30 wherein R¹ is Y-8A and R² is CH₃. Table 2020. Formula I.30 wherein R¹ is Y-8B and R² is CH₃. Table 2021. Formula I.30 wherein R¹ is Y-1A and R² is c-C₃H₅. Table 2022. Formula I.30 wherein R¹ is Y-1B and R² is c-C₃H₅. Table 2023. Formula I.30 wherein R¹ is Y-2A and R² is c-C₃H₅. Table 2024. Formula I.30 wherein R¹ is Y-2B and R² is c-C₃H₅. Table 2025. Formula I.30 wherein R¹ is Y-3A and R² is c-C₃H₅. Table 2026. Formula I.30 wherein R¹ is Y-3B and R² is c-C₃H₅. Table 2027. Formula I.30 wherein R¹ is Y-3C and R² is c-C₃H₅. Table 2028. Formula I.30 wherein R¹ is Y-3D and R² is c-C₃H₅. Table 2029. Formula I.30 wherein R¹ is Y-4A and R² is c-C₃H₅. Table 2030. Formula I.30 wherein R¹ is Y-4B and R² is c-C₃H₅. Table 2031. Formula I.30 wherein R¹ is Y-4C and R² is c-C₃H₅. Table 2032. Formula I.30 wherein R¹ is Y-4D and R² is c-C₃H₅. Table 2033. Formula I.30 wherein R¹ is Y-5A and R² is c-C₃H₅. Table 2034. Formula I.30 wherein R¹ is Y-5B and R² is c-C₃H₅. Table 2035. Formula I.30 wherein R¹ is Y-6A and R² is c-C₃H₅. Table 2036. Formula I.30 wherein R¹ is Y-6B and R² is c-C₃H₅. Table 2037. Formula I.30 wherein R¹ is Y-7A and R² is c-C₃H₅. Table 2038. Formula I.30 wherein R¹ is Y-7B and R² is c-C₃H₅. Table 2039. Formula I.30 wherein R¹ is Y-8A and R² is c-C₃H₅. Table 2040. Formula I.30 wherein R¹ is Y-8B and R² is c-C₃H₅. Table 2041. Formula I.31 wherein R¹ is Y-1A and R² is H. Table 2042. Formula I.31 wherein R¹ is Y-1B and R² is H. Table 2043. Formula I.31 wherein R¹ is Y-2A and R² is H. Table 2044. Formula I.31 wherein R¹ is Y-2B and R² is H. Table 2045. Formula I.31 wherein R¹ is Y-3A and R² is H. Table 2046. Formula I.31 wherein R¹ is Y-3B and R² is H. Table 2047. Formula I.31 wherein R¹ is Y-3C and R² is H. Table 2048. Formula I.31 wherein R¹ is Y-3D and R² is H. Table 2049. Formula I.31 wherein R¹ is Y-4A and R² is H. Table 2050. Formula I.31 wherein R¹ is Y-4B and R² is H. Table 2051. Formula I.31 wherein R¹ is Y-4C and R² is H. Table 2052. Formula I.31 wherein R¹ is Y-4D and R² is H. Table 2053. Formula I.31 wherein R¹ is Y-5A and R² is H. Table 2054. Formula I.31 wherein R¹ is Y-5B and R² is H. Table 2055. Formula I.31 wherein R¹ is Y-6A and R² is H. Table 2056. Formula I.31 wherein R¹ is Y-6B and R² is H. Table 2057. Formula I.31 wherein R¹ is Y-7A and R² is H. Table 2058. Formula I.31 wherein R¹ is Y-7B and R² is H. Table 2059. Formula I.31 wherein R¹ is Y-8A and R² is H. Table 2060. Formula I.31 wherein R¹ is Y-8B and R² is H. Table 2061. Formula I.31 wherein R¹ is Y-1A and R² is CH₃. Table 2062. Formula I.31 wherein R¹ is Y-1B and R² is CH₃. Table 2063. Formula I.31 wherein R¹ is Y-2A and R² is CH₃. Table 2064. Formula I.31 wherein R¹ is Y-2B and R² is CH₃. Table 2065. Formula I.31 wherein R¹ is Y-3A and R² is CH₃. Table 2066. Formula I.31 wherein R¹ is Y-3B and R² is CH₃. Table 2067. Formula I.31 wherein R¹ is Y-3C and R² is CH₃. Table 2068. Formula I.31 wherein R¹ is Y-3D and R² is CH₃. Table 2069. Formula I.31 wherein R¹ is Y-4A and R² is CH₃. Table 2070. Formula I.31 wherein R¹ is Y-4B and R² is CH₃. Table 2071. Formula I.31 wherein R¹ is Y-4C and R² is CH₃. Table 2072. Formula I.31 wherein R¹ is Y-4D and R² is CH₃. Table 2073. Formula I.31 wherein R¹ is Y-5A and R² is CH₃. Table 2074. Formula I.31 wherein R¹ is Y-5B and R² is CH₃. Table 2075. Formula I.31 wherein R¹ is Y-6A and R² is CH₃. Table 2076. Formula I.31 wherein R¹ is Y-6B and R² is CH₃. Table 2077. Formula I.31 wherein R¹ is Y-7A and R² is CH₃. Table 2078. Formula I.31 wherein R¹ is Y-7B and R² is CH₃. Table 2079. Formula I.31 wherein R¹ is Y-8A and R² is CH₃. Table 2080. Formula I.31 wherein R¹ is Y-8B and R² is CH₃. Table 2081. Formula I.31 wherein R¹ is Y-1A and R² is c-C₃H₅. Table 2082. Formula I.31 wherein R¹ is Y-1B and R² is c-C₃H₅. Table 2083. Formula I.31 wherein R¹ is Y-2A and R² is c-C₃H₅. Table 2084. Formula I.31 wherein R¹ is Y-2B and R² is c-C₃H₅. Table 2085. Formula I.31 wherein R¹ is Y-3A and R² is c-C₃H₅. Table 2086. Formula I.31 wherein R¹ is Y-3B and R² is c-C₃H₅. Table 2087. Formula I.31 wherein R¹ is Y-3C and R² is c-C₃H₅. Table 2088. Formula I.31 wherein R¹ is Y-3D and R² is c-C₃H₅. Table 2089. Formula I.31 wherein R¹ is Y-4A and R² is c-C₃H₅. Table 2090. Formula I.31 wherein R¹ is Y-4B and R² is c-C₃H₅. Table 2091. Formula I.31 wherein R¹ is Y-4C and R² is c-C₃H₅. Table 2092. Formula I.31 wherein R¹ is Y-4D and R² is c-C₃H₅. Table 2093. Formula I.31 wherein R¹ is Y-5A and R² is c-C₃H₅. Table 2094. Formula I.31 wherein R¹ is Y-5B and R² is c-C₃H₅. Table 2095. Formula I.31 wherein R¹ is Y-6A and R² is c-C₃H₅. Table 2096. Formula I.31 wherein R¹ is Y-6B and R² is c-C₃H₅. Table 2097. Formula I.31 wherein R¹ is Y-7A and R² is c-C₃H₅. Table 2098. Formula I.31 wherein R¹ is Y-7B and R² is c-C₃H₅. Table 2099. Formula I.31 wherein R¹ is Y-8A and R² is c-C₃H₅. Table 2100. Formula I.31 wherein R¹ is Y-8B and R² is c-C₃H₅. Table 2101. Formula I.32 wherein R¹ is Y-1A and R² is H. Table 2102. Formula I.32 wherein R¹ is Y-1B and R² is H. Table 2103. Formula I.32 wherein R¹ is Y-2A and R² is H. Table 2104. Formula I.32 wherein R¹ is Y-2B and R² is H. Table 2105. Formula I.32 wherein R¹ is Y-3A and R² is H. Table 2106. Formula I.32 wherein R¹ is Y-3B and R² is H. Table 2107. Formula I.32 wherein R¹ is Y-3C and R² is H. Table 2108. Formula I.32 wherein R¹ is Y-3D and R² is H. Table 2109. Formula I.32 wherein R¹ is Y-4A and R² is H. Table 2110. Formula I.32 wherein R¹ is Y-4B and R² is H. Table 2111. Formula I.32 wherein R¹ is Y-4C and R² is H. Table 2112. Formula I.32 wherein R¹ is Y-4D and R² is H. Table 2113. Formula I.32 wherein R¹ is Y-5A and R² is H. Table 2114. Formula I.32 wherein R¹ is Y-5B and R² is H. Table 2115. Formula I.32 wherein R¹ is Y-6A and R² is H. Table 2116. Formula I.32 wherein R¹ is Y-6B and R² is H. Table 2117. Formula I.32 wherein R¹ is Y-7A and R² is H. Table 2118. Formula I.32 wherein R¹ is Y-7B and R² is H. Table 2119. Formula I.32 wherein R¹ is Y-8A and R² is H. Table 2120. Formula I.32 wherein R¹ is Y-8B and R² is H. Table 2121. Formula I.32 wherein R¹ is Y-1A and R² is CH₃. Table 2122. Formula I.32 wherein R¹ is Y-1B and R² is CH₃. Table 2123. Formula I.32 wherein R¹ is Y-2A and R² is CH₃. Table 2124. Formula I.32 wherein R¹ is Y-2B and R² is CH₃. Table 2125. Formula I.32 wherein R¹ is Y-3A and R² is CH₃. Table 2126. Formula I.32 wherein R¹ is Y-3B and R² is CH₃. Table 2127. Formula I.32 wherein R¹ is Y-3C and R² is CH₃. Table 2128. Formula I.32 wherein R¹ is Y-3D and R² is CH₃. Table 2129. Formula I.32 wherein R¹ is Y-4A and R² is CH₃. Table 2130. Formula I.32 wherein R¹ is Y-4B and R² is CH₃. Table 2131. Formula I.32 wherein R¹ is Y-4C and R² is CH₃. Table 2132. Formula I.32 wherein R¹ is Y-4D and R² is CH₃. Table 2133. Formula I.32 wherein R¹ is Y-5A and R² is CH₃. Table 2134. Formula I.32 wherein R¹ is Y-5B and R² is CH₃. Table 2135. Formula I.32 wherein R¹ is Y-6A and R² is CH₃. Table 2136. Formula I.32 wherein R¹ is Y-6B and R² is CH₃. Table 2137. Formula I.32 wherein R¹ is Y-7A and R² is CH₃. Table 2138. Formula I.32 wherein R¹ is Y-7B and R² is CH₃. Table 2139. Formula I.32 wherein R¹ is Y-8A and R² is CH₃. Table 2140. Formula I.32 wherein R¹ is Y-8B and R² is CH₃. Table 2141. Formula I.32 wherein R¹ is Y-1A and R² is c-C₃H₅. Table 2142. Formula I.32 wherein R¹ is Y-1B and R² is c-C₃H₅. Table 2143. Formula I.32 wherein R¹ is Y-2A and R² is c-C₃H₅. Table 2144. Formula I.32 wherein R¹ is Y-2B and R² is c-C₃H₅. Table 2145. Formula I.32 wherein R¹ is Y-3A and R² is c-C₃H₅. Table 2146. Formula I.32 wherein R¹ is Y-3B and R² is c-C₃H₅. Table 2147. Formula I.32 wherein R¹ is Y-3C and R² is c-C₃H₅. Table 2148. Formula I.32 wherein R¹ is Y-3D and R² is c-C₃H₅. Table 2149. Formula I.32 wherein R¹ is Y-4A and R² is c-C₃H₅. Table 2150. Formula I.32 wherein R¹ is Y-4B and R² is c-C₃H₅. Table 2151. Formula I.32 wherein R¹ is Y-4C and R² is c-C₃H₅. Table 2152. Formula I.32 wherein R¹ is Y-4D and R² is c-C₃H₅. Table 2153. Formula I.32 wherein R¹ is Y-5A and R² is c-C₃H₅. Table 2154. Formula I.32 wherein R¹ is Y-5B and R² is c-C₃H₅. Table 2155. Formula I.32 wherein R¹ is Y-6A and R² is c-C₃H₅. Table 2156. Formula I.32 wherein R¹ is Y-6B and R² is c-C₃H₅. Table 2157. Formula I.32 wherein R¹ is Y-7A and R² is c-C₃H₅. Table 2158. Formula I.32 wherein R¹ is Y-7B and R² is c-C₃H₅. Table 2159. Formula I.32 wherein R¹ is Y-8A and R² is c-C₃H₅. Table 2160. Formula I.32 wherein R¹ is Y-8B and R² is c-C₃H₅.

TABLE B Line B¹ B² B³ Ar D 1 CH CH CH Ar¹ R¹¹-1 2 CH CH CH Ar¹ R¹¹-2 3 CH CH CH Ar¹ R¹¹-3 4 CH CH CH Ar¹ R¹¹-4 5 CH CH CH Ar¹ R¹¹-5 6 CH CH CH Ar¹ R¹¹-6 7 CH CH CH Ar¹ R¹¹-7 8 CH CH CH Ar¹ R¹¹-8 9 CH CH CH Ar¹ R¹¹-9 10 CH CH CH Ar¹ R¹¹-10 11 CH CH CH Ar¹ R¹¹-11 12 CH CH CH Ar¹ R¹¹-12 13 CH CH CH Ar¹ R¹¹-13 14 CH CH CH Ar¹ R¹¹-14 15 CH CH CH Ar¹ R¹¹-15 16 CH CH CH Ar¹ R¹¹-16 17 CH CH CH Ar¹ R¹¹-17 18 CH CH CH Ar¹ R¹¹-18 19 CH CH CH Ar¹ R¹¹-19 20 CH CH CH Ar¹ R¹¹-20 21 CH CH CH Ar¹ R¹¹-21 22 CH CH CH Ar¹ R¹¹-22 23 CH CH CH Ar¹ R¹¹-23 24 CH CH CH Ar¹ R¹¹-24 25 CH CH CH Ar¹ R¹¹-25 26 CH CH CH Ar¹ R¹¹-26 27 CH CH CH Ar¹ R¹¹-27 28 CH CH CH Ar¹ R¹¹-28 29 CH CH CH Ar¹ R¹¹-29 30 CH CH CH Ar¹ A¹¹-1 31 CH CH CH Ar¹ A¹¹-2 32 CH CH CH Ar¹ A¹¹-3 33 CH CH CH Ar² R¹¹-1 34 CH CH CH Ar² R¹¹-2 35 CH CH CH Ar² R¹¹-3 36 CH CH CH Ar² R¹¹-4 37 CH CH CH Ar² R¹¹-5 38 CH CH CH Ar² R¹¹-6 39 CH CH CH Ar² R¹¹-7 40 CH CH CH Ar² R¹¹-8 41 CH CH CH Ar² R¹¹-9 42 CH CH CH Ar² R¹¹-10 43 CH CH CH Ar² R¹¹-11 44 CH CH CH Ar² R¹¹-12 45 CH CH CH Ar² R¹¹-13 46 CH CH CH Ar² R¹¹-14 47 CH CH CH Ar² R¹¹-15 48 CH CH CH Ar² R¹¹-16 49 CH CH CH Ar² R¹¹-17 50 CH CH CH Ar² R¹¹-18 51 CH CH CH Ar² R¹¹-19 52 CH CH CH Ar² R¹¹-20 53 CH CH CH Ar² R¹¹-21 54 CH CH CH Ar² R¹¹-22 55 CH CH CH Ar² R¹¹-23 56 CH CH CH Ar² R¹¹-24 57 CH CH CH Ar² R¹¹-25 58 CH CH CH Ar² R¹¹-26 59 CH CH CH Ar² R¹¹-27 60 CH CH CH Ar² R¹¹-28 61 CH CH CH Ar² R¹¹-29 62 CH CH CH Ar² A¹¹-1 63 CH CH CH Ar² A¹¹-2 64 CH CH CH Ar² A¹¹-3 65 CH CH CH Ar³ R¹¹-1 66 CH CH CH Ar³ R¹¹-2 67 CH CH CH Ar³ R¹¹-3 68 CH CH CH Ar³ R¹¹-4 69 CH CH CH Ar³ R¹¹-5 70 CH CH CH Ar³ R¹¹-6 71 CH CH CH Ar³ R¹¹-7 72 CH CH CH Ar³ R¹¹-8 73 CH CH CH Ar³ R¹¹-9 74 CH CH CH Ar³ R¹¹-10 75 CH CH CH Ar³ R¹¹-11 76 CH CH CH Ar³ R¹¹-12 77 CH CH CH Ar³ R¹¹-13 78 CH CH CH Ar³ R¹¹-14 79 CH CH CH Ar³ R¹¹-15 80 CH CH CH Ar³ R¹¹-16 81 CH CH CH Ar³ R¹¹-17 82 CH CH CH Ar³ R¹¹-18 83 CH CH CH Ar³ R¹¹-19 84 CH CH CH Ar³ R¹¹-20 85 CH CH CH Ar³ R¹¹-21 86 CH CH CH Ar³ R¹¹-22 87 CH CH CH Ar³ R¹¹-23 88 CH CH CH Ar³ R¹¹-24 89 CH CH CH Ar³ R¹¹-25 90 CH CH CH Ar³ R¹¹-26 91 CH CH CH Ar³ R¹¹-27 92 CH CH CH Ar³ R¹¹-28 93 CH CH CH Ar³ R¹¹-29 94 CH CH CH Ar³ A¹¹-1 95 CH CH CH Ar³ A¹¹-2 96 CH CH CH Ar³ A¹¹-3 97 CH CH CH Ar⁴ R¹¹-1 98 CH CH CH Ar⁴ R¹¹-2 99 CH CH CH Ar⁴ R¹¹-3 100 CH CH CH Ar⁴ R¹¹-4 101 CH CH CH Ar⁴ R¹¹-5 102 CH CH CH Ar⁴ R¹¹-6 103 CH CH CH Ar⁴ R¹¹-7 104 CH CH CH Ar⁴ R¹¹-8 105 CH CH CH Ar⁴ R¹¹-9 106 CH CH CH Ar⁴ R¹¹-10 107 CH CH CH Ar⁴ R¹¹-11 108 CH CH CH Ar⁴ R¹¹-12 109 CH CH CH Ar⁴ R¹¹-13 110 CH CH CH Ar⁴ R¹¹-14 111 CH CH CH Ar⁴ R¹¹-15 112 CH CH CH Ar⁴ R¹¹-16 113 CH CH CH Ar⁴ R¹¹-17 114 CH CH CH Ar⁴ R¹¹-18 115 CH CH CH Ar⁴ R¹¹-19 116 CH CH CH Ar⁴ R¹¹-20 117 CH CH CH Ar⁴ R¹¹-21 118 CH CH CH Ar⁴ R¹¹-22 119 CH CH CH Ar⁴ R¹¹-23 120 CH CH CH Ar⁴ R¹¹-24 121 CH CH CH Ar⁴ R¹¹-25 122 CH CH CH Ar⁴ R¹¹-26 123 CH CH CH Ar⁴ R¹¹-27 124 CH CH CH Ar⁴ R¹¹-28 125 CH CH CH Ar⁴ R¹¹-29 126 CH CH CH Ar⁴ A¹¹-1 127 CH CH CH Ar⁴ A¹¹-2 128 CH CH CH Ar⁴ A¹¹-3 129 CH CH CH Ar¹⁰ R¹¹-1 130 CH CH CH Ar¹⁰ R¹¹-2 131 CH CH CH Ar¹⁰ R¹¹-3 132 CH CH CH Ar¹⁰ R¹¹-4 133 CH CH CH Ar¹⁰ R¹¹-5 134 CH CH CH Ar¹⁰ R¹¹-6 135 CH CH CH Ar¹⁰ R¹¹-7 136 CH CH CH Ar¹⁰ R¹¹-8 137 CH CH CH Ar¹⁰ R¹¹-9 138 CH CH CH Ar¹⁰ R¹¹-10 139 CH CH CH Ar¹⁰ R¹¹-11 140 CH CH CH Ar¹⁰ R¹¹-12 141 CH CH CH Ar¹⁰ R¹¹-13 142 CH CH CH Ar¹⁰ R¹¹-14 143 CH CH CH Ar¹⁰ R¹¹-15 144 CH CH CH Ar¹⁰ R¹¹-16 145 CH CH CH Ar¹⁰ R¹¹-17 146 CH CH CH Ar¹⁰ R¹¹-18 147 CH CH CH Ar¹⁰ R¹¹-19 148 CH CH CH Ar¹⁰ R¹¹-20 149 CH CH CH Ar¹⁰ R¹¹-21 150 CH CH CH Ar¹⁰ R¹¹-22 151 CH CH CH Ar¹⁰ R¹¹-23 152 CH CH CH Ar¹⁰ R¹¹-24 153 CH CH CH Ar¹⁰ R¹¹-25 154 CH CH CH Ar¹⁰ R¹¹-26 155 CH CH CH Ar¹⁰ R¹¹-27 156 CH CH CH Ar¹⁰ R¹¹-28 157 CH CH CH Ar¹⁰ R¹¹-29 158 CH CH CH Ar¹⁰ A¹¹-1 159 CH CH CH Ar¹⁰ A¹¹-2 160 CH CH CH Ar¹⁰ A¹¹-3 161 CH CH CH Ar¹⁷ R¹¹-1 162 CH CH CH Ar¹⁷ R¹¹-2 163 CH CH CH Ar¹⁷ R¹¹-3 164 CH CH CH Ar¹⁷ R¹¹-4 165 CH CH CH Ar¹⁷ R¹¹-5 166 CH CH CH Ar¹⁷ R¹¹-6 167 CH CH CH Ar¹⁷ R¹¹-7 168 CH CH CH Ar¹⁷ R¹¹-8 169 CH CH CH Ar¹⁷ R¹¹-9 170 CH CH CH Ar¹⁷ R¹¹-10 171 CH CH CH Ar¹⁷ R¹¹-11 172 CH CH CH Ar¹⁷ R¹¹-12 173 CH CH CH Ar¹⁷ R¹¹-13 174 CH CH CH Ar¹⁷ R¹¹-14 175 CH CH CH Ar¹⁷ R¹¹-15 176 CH CH CH Ar¹⁷ R¹¹-16 177 CH CH CH Ar¹⁷ R¹¹-17 178 CH CH CH Ar¹⁷ R¹¹-18 179 CH CH CH Ar¹⁷ R¹¹-19 180 CH CH CH Ar¹⁷ R¹¹-20 181 CH CH CH Ar¹⁷ R¹¹-21 182 CH CH CH Ar¹⁷ R¹¹-22 183 CH CH CH Ar¹⁷ R¹¹-23 184 CH CH CH Ar¹⁷ R¹¹-24 185 CH CH CH Ar¹⁷ R¹¹-25 186 CH CH CH Ar¹⁷ R¹¹-26 187 CH CH CH Ar¹⁷ R¹¹-27 188 CH CH CH Ar¹⁷ R¹¹-28 189 CH CH CH Ar¹⁷ R¹¹-29 190 CH CH CH Ar¹⁷ A¹¹-1 191 CH CH CH Ar¹⁷ A¹¹-2 192 CH CH CH Ar¹⁷ A¹¹-3 193 CH CH CH Ar¹⁸ R¹¹-1 194 CH CH CH Ar¹⁸ R¹¹-2 195 CH CH CH Ar¹⁸ R¹¹-3 196 CH CH CH Ar¹⁸ R¹¹-4 197 CH CH CH Ar¹⁸ R¹¹-5 198 CH CH CH Ar¹⁸ R¹¹-6 199 CH CH CH Ar¹⁸ R¹¹-7 200 CH CH CH Ar¹⁸ R¹¹-8 201 CH CH CH Ar¹⁸ R¹¹-9 202 CH CH CH Ar¹⁸ R¹¹-10 203 CH CH CH Ar¹⁸ R¹¹-11 204 CH CH CH Ar¹⁸ R¹¹-12 205 CH CH CH Ar¹⁸ R¹¹-13 206 CH CH CH Ar¹⁸ R¹¹-14 207 CH CH CH Ar¹⁸ R¹¹-15 208 CH CH CH Ar¹⁸ R¹¹-16 209 CH CH CH Ar¹⁸ R¹¹-17 210 CH CH CH Ar¹⁸ R¹¹-18 211 CH CH CH Ar¹⁸ R¹¹-19 212 CH CH CH Ar¹⁸ R¹¹-20 213 CH CH CH Ar¹⁸ R¹¹-21 214 CH CH CH Ar¹⁸ R¹¹-22 215 CH CH CH Ar¹⁸ R¹¹-23 216 CH CH CH Ar¹⁸ R¹¹-24 217 CH CH CH Ar¹⁸ R¹¹-25 218 CH CH CH Ar¹⁸ R¹¹-26 219 CH CH CH Ar¹⁸ R¹¹-27 220 CH CH CH Ar¹⁸ R¹¹-28 221 CH CH CH Ar¹⁸ R¹¹-29 222 CH CH CH Ar¹⁸ A¹¹-1 223 CH CH CH Ar¹⁸ A¹¹-2 224 CH CH CH Ar¹⁸ A¹¹-3

As used herein, the term “compound(s) of the present invention” or “compound(s) according to the invention” refers to the compound(s) of formula (I) as defined above, which are also referred to as “compound(s) of formula I” or “compound(s) I” or “formula I compound(s)”, and includes their salts, tautomers, stereoisomers, and N-oxides.

The present invention also relates to a mixture of at least one compound of the present invention with at least one mixing partner as defined herein after. Preferred are binary mixtures of one compound of the present invention as component I with one mixing partner as defined herein after as component II. Preferred weight ratios for such binary mixtures are from 5000:1 to 1:5000, preferably from 1000:1 to 1:1000, more preferably from 100:1 to 1:100, particularly preferably from 10:1 to 1:10. In such binary mixtures, components I and II may be used in equal amounts, or an excess of component I, or an excess of component II may be used.

Mixing partners can be selected from pesticides, in particular insecticides, nematicides, and acaricides, fungicides, herbicides, plant growth regulators, fertilizers, and the like. Preferred mixing partners are insecticides, nematicides and fungicides.

The following list M of pesticides, grouped and numbered according the Mode of Action Classification of the Insecticide Resistance Action Committee (IRAC), together with which the compounds of the present invention can be used and with which potential synergistic effects might be produced, is intended to illustrate the possible combinations, but not to impose any limitation:

M.1 Acetylcholine esterase (AChE) inhibitors from the class of: M.1A carbamates, for example aldicarb, alanycarb, bendiocarb, benfuracarb, butocarboxim, butoxycarboxim, carbaryl, carbofuran, carbosulfan, ethiofencarb, fenobucarb, formetanate, furathiocarb, isoprocarb, methiocarb, methomyl, metolcarb, oxamyl, pirimicarb, propoxur, thiodicarb, thiofanox, trimethacarb, XMC, xylylcarb and triazamate; or from the class of M.1B organophosphates, for example acephate, azamethiphos, azinphos-ethyl, azinphosmethyl, cadusafos, chlorethoxyfos, chlorfenvinphos, chlormephos, chlorpyrifos, chlorpyrifos-methyl, coumaphos, cyanophos, demeton-S-methyl, diazinon, dichlorvos/DDVP, dicrotophos, dimethoate, dimethylvinphos, disulfoton, EPN, ethion, ethoprophos, famphur, fenamiphos, fenitrothion, fenthion, fosthiazate, heptenophos, imicyafos, isofenphos, isopropyl O-(methoxyaminothio-phosphoryl) salicylate, isoxathion, malathion, mecarbam, methamidophos, methidathion, mevinphos, monocrotophos, naled, omethoate, oxydemeton-methyl, parathion, parathion-methyl, phenthoate, phorate, phosalone, phosmet, phosphamidon, phoxim, pirimiphos-methyl, profenofos, propetamphos, prothiofos, pyraclofos, pyridaphenthion, quinalphos, sulfotep, tebupirimfos, temephos, terbufos, tetrachlorvinphos, thiometon, triazophos, trichlorfon and vamidothion;

M.2. GABA-gated chloride channel antagonists such as: M.2A cyclodiene organochlorine compounds, as for example endosulfan or chlordane; or M.2B fiproles (phenylpyrazoles), as for example ethiprole, fipronil, flufiprole, pyrafluprole and pyriprole;

M.3 Sodium channel modulators from the class of M.3A pyrethroids, for example acrinathrin, allethrin, d-cis-trans allethrin, d-trans allethrin, bifenthrin, bioallethrin, bioallethrin S-cylclopentenyl, bioresmethrin, cycloprothrin, cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda-cyhalothrin, gamma-cyhalothrin, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, cyphenothrin, deltamethrin, empenthrin, esfenvalerate, etofenprox, fenpropathrin, fenvalerate, flucythrinate, flumethrin, tau-fluvalinate, halfenprox, heptafluthrin, imiprothrin, meperfluthrin, metofluthrin, momfluorothrin, permethrin, phenothrin, prallethrin, profluthrin, pyrethrin (pyrethrum), resmethrin, silafluofen, tefluthrin, tetramethylfluthrin, tetramethrin, tralomethrin and transfluthrin; or M.3B sodium channel modulators such as DDT or methoxychlor;

M.4 Nicotinic acetylcholine receptor agonists (nAChR) from the class of M.4A neonicotinoids, for example acetamiprid, clothianidin, cycloxaprid, dinotefuran, imidacloprid, nitenpyram, thiacloprid and thiamethoxam; or the compounds M.4A.2: (2E-)-1-[(6-Chloropyridin-3-yl)methyl]-N′-nitro-2-pentylidenehydrazinecarboximidamide; or M4.A.3: 1-[(6-Chloropyridin-3-yl)methyl]-7-methyl-8-nitro-5-propoxy-1,2,3,5,6,7-hexahydroimidazo[1,2-a]pyridine; or from the class M.4B nicotine;

M.5 Nicotinic acetylcholine receptor allosteric activators from the class of spinosyns, for example spinosad or spinetoram;

M.6 Chloride channel activators from the class of avermectins and milbemycins, for example abamectin, emamectin benzoate, ivermectin, lepimectin or milbemectin;

M.7 Juvenile hormone mimics, such as M.7A juvenile hormone analogues as hydroprene, kinoprene and methoprene; or others as M.7B fenoxycarb or M.7C pyriproxyfen;

M.8 miscellaneous non-specific (multi-site) inhibitors, for example M.8A alkyl halides as methyl bromide and other alkyl halides, or M.8B chloropicrin, or M.8C sulfuryl fluoride, or M.8D borax, or M.8E tartar emetic;

M.9 Selective homopteran feeding blockers, for example M.9B pymetrozine, or M.9C flonicamid;

M.10 Mite growth inhibitors, for example M.10A clofentezine, hexythiazox and diflovidazin, or M.10B etoxazole;

M.11 Microbial disruptors of insect midgut membranes, for example Bacillus thuringiensis or Bacillus sphaericus and the insecticdal proteins they produce such as Bacillus thuringiensis subsp. israelensis, Bacillus sphaericus, Bacillus thuringiensis subsp. aizawai, Bacillus thuringiensis subsp. kurstaki and Bacillus thuringiensis subsp. tenebrionis, or the Bt crop proteins: Cry1Ab, Cry1Ac, Cry1Fa, Cry2Ab, mCry3A, Cry3Ab, Cry3Bb and Cry34/35Ab1;

M.12 Inhibitors of mitochondrial ATP synthase, for example M.12A diafenthiuron, or M.12B organotin miticides such as azocyclotin, cyhexatin or fenbutatin oxide, or M.12C propargite, or M.12D tetradifon;

M.13 Uncouplers of oxidative phosphorylation via disruption of the proton gradient, for example chlorfenapyr, DNOC or sulfluramid;

M.14 Nicotinic acetylcholine receptor (nAChR) channel blockers, for example nereistoxin analogues as bensultap, cartap hydrochloride, thiocyclam orthiosultap sodium;

M.15 Inhibitors of the chitin biosynthesis type 0, such as benzoylureas as for example bistrifluron, chlorfluazuron, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron or triflumuron;

M.16 Inhibitors of the chitin biosynthesis type 1, as for example buprofezin;

M.17 Moulting disruptors, Dipteran, as for example cyromazine;

M.18 Ecdyson receptor agonists such as diacylhydrazines, for example methoxyfenozide, tebufenozide, halofenozide, fufenozide or chromafenozide;

M.19 Octopamin receptor agonists, as for example amitraz;

M.20 Mitochondrial complex III electron transport inhibitors, for example M.20A hydramethylnon, or M.20B acequinocyl, or M.20C fluacrypyrim;

M.21 Mitochondrial complex I electron transport inhibitors, for example M.21A METI acaricides and insecticides such as fenazaquin, fenpyroximate, pyrimidifen, pyridaben, tebufenpyrad or tolfenpyrad, or M.21B rotenone;

M.22 Voltage-dependent sodium channel blockers, for example M.22A indoxacarb, or M.22B metaflumizone, or M.22B.1: 2-[2-(4-Cyanophenyl)-1-[3-(trifluoromethyl)phenyl]-ethylidene]-N-[4-(difluoromethoxy)phenyl]-hydrazinecarboxamide or M.22B.2: N-(3-Chloro-2-methylphenyl)-2-[(4-chlorophenyl)[4-[methyl(methylsulfonyl)amino]phenyl]methylene]-hydrazinecarboxamide;

M.23 Inhibitors of the of acetyl CoA carboxylase, such as Tetronic and Tetramic acid derivatives, for example spirodiclofen, spiromesifen or spirotetramat;

M.24 Mitochondrial complex IV electron transport inhibitors, for example M.24A phosphine such as aluminium phosphide, calcium phosphide, phosphine or zinc phosphide, or M.24B cyanide;

M.25 Mitochondrial complex II electron transport inhibitors, such as beta-ketonitrile derivatives, for example cyenopyrafen or cyflumetofen;

M.28 Ryanodine receptor-modulators from the class of diamides, as for example flubendiamide, chlorantraniliprole (Rynaxypyr®), cyantraniliprole (Cyazypyr®), tetraniliprole, or the phthalamide compounds M.28.1: (R)-3-Chlor-N1-{2-methyl-4-[1,2,2,2-tetrafluor-1-(trifluormethyl)ethyl]phenyl}-N2-(1-methyl-2-methylsulfonylethyl)phthalamid and M.28.2: (S)-3-Chlor-N1-{2-methyl-4-[1,2,2,2-tetrafluor-1-(trifluormethyl)ethyl]phenyl}-N2-(1-methyl-2-methylsulfonylethyl)phthalamid, or the compound M.28.3: 3-bromo-N-{2-bromo-4-chloro-6-[(1-cyclopropylethyl)carbamoyl]phenyl}-1-(3-chlorpyridin-2-yl)-1H-pyrazole-5-carboxamide (proposed ISO name: cyclaniliprole), or the compound M.28.4: methyl-2-[3,5-dibromo-2-({[3-bromo-1-(3-chlorpyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)benzoyl]-1,2-dimethylhydrazinecarboxylate; or a compound selected from M.28.5a) to M.28.5d) and M.28.5h) to M.28.5l): M.28.5a) N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)-carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5b) N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5c) N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5d) N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5h) N-[4,6-dibromo-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5i) N-[2-(5-Amino-1,3,4-thiadiazol-2-yl)-4-chloro-6-methylphenyl]-3-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide; M.28.5j) 3-Chloro-1-(3-chloro-2-pyridinyl)-N-[2,4-dichloro-6-[[(1-cyano-1-methylethyl)amino]carbonyl]phenyl]-1H-pyrazole-5-carboxamide; M.28.5k) 3-Bromo-N-[2,4-dichloro-6-(methylcarbamoyl)phenyl]-1-(3,5-dichloro-2-pyridyl)-1H-pyrazole-5-carboxamide; M.28.5l) N-[4-Chloro-2-[[(1,1-dimethylethyl)amino]carbonyl]-6-methylphenyl]-1-(3-chloro-2-pyridinyl)-3-(fluoromethoxy)-1H-pyrazole-5-carboxamide; or

M.28.6: cyhalodiamide; or;

M.29. insecticidal active compounds of unknown or uncertain mode of action, as for example afidopyropen, afoxolaner, azadirachtin, amidoflumet, benzoximate, bifenazate, broflanilide, bromopropylate, chinomethionat, cryolite, dicloromezotiaz, dicofol, flufenerim, flometoquin, fluensulfone, fluhexafon, fluopyram, flupyradifurone, fluralaner, metoxadiazone, piperonyl butoxide, pyflubumide, pyridalyl, pyrifluquinazon, sulfoxaflor, tioxazafen, triflumezopyrim, or the compounds

M.29.3: 11-(4-chloro-2,6-dimethylphenyl)-12-hydroxy-1,4-dioxa-9-azadispiro[4.2.4.2]-tetradec-11-en-10-one, or the compound

M.29.4: 3-(4′-fluoro-2,4-dimethylbiphenyl-3-yl)-4-hydroxy-8-oxa-1-azaspiro[4.5]dec-3-en-2-one, or the compound

M.29.5: 1-[2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenyl]-3-(trifluoromethyl)-1H-1,2,4-triazole-5-amine, or actives on basis of Bacillus firmus (Votivo, I-1582); or

a compound selected from the of M.29.6, wherein the compound M.29.6a) to M.29.6k): M.29.6a) (E/Z)—N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide; M.29.6b) (E/Z)—N-[1-[(6-chloro-5-fluoro-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide; M.29.6c) (E/Z)-2,2,2-trifluoro-N-[1-[(6-fluoro-3-pyridyl)methyl]-2-pyridylidene]acetamide; M.29.6d) (E/Z)—N-[1-[(6-bromo-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide; M.29.6e) (E/Z)—N-[1-[1-(6-chloro-3-pyridyl)ethyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide; M.29.6f) (E/Z)—N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2-difluoro-acetamide; M.29.6g) (E/Z)-2-chloro-N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2-difluoro-acetamide; M.29.6h) (E/Z)—N-[1-[(2-chloropyrimidin-5-yl)methyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide; M.29.6i) (E/Z)—N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2,3,3,3-pentafluoro-propanamide.); M.29.6j) N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-thioacetamide; or M.29.6k) N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-N′-isopropyl-acetamidine; or the compounds

M.29.8: fluazaindolizine; or the compounds

M.29.9.a): 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isoxazol-3-yl]-2-methyl-N-(1-oxothietan-3-yl)benzamide; or M.29.9.b): fluxametamide; or

M.29.10: 5-[3-[2,6-dichloro-4-(3,3-dichloroallyloxy)phenoxy]propoxy]-1H-pyrazole; or a compound selected from the of M.29.11, wherein the compound M.29.11 b) to M.29.11p): M.29.11.b) 3-(benzoylmethylamino)-N-[2-bromo-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]-6-(trifluoromethyl)phenyl]-2-fluoro-benzamide; M.29.11.c) 3-(benzoyl-methylamino)-2-fluoro-N-[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoro-methyl)phenyl]-benzamide; M.29.11.d) N-[3-[[[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-N-methyl-benzamide; M.29.11.e) N-[3-[[[2-bromo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]amino]carbonyl]-2-fluorophenyl]-4-fluoro-N-methyl-benzamide; M.29.11.f) 4-fluoro-N-[2-fluoro-3-[[[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-N-methyl-benzamide; M.29.11.g) 3-fluoro-N-[2-fluoro-3-[[[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoro-methyl)phenyl]amino]carbonyl]phenyl]-N-methyl-benzamide; M.29.11.h) 2-chloro-N-[3-[[[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-3-pyridinecarboxamide; M.29.11.i) 4-cyano-N-[2-cyano-5-[[2,6-dibromo-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]phenyl]carbamoyl]phenyl]-2-methyl-benzamide; M.29.11.j) 4-cyano-3-[(4-cyano-2-methyl-benzoyl)amino]-N-[2,6-dichloro-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]phenyl]-2-fluoro-benzamide; M.29.11.k) N-[5-[[2-chloro-6-cyano-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]phenyl]carbamoyl]-2-cyano-phenyl]-4-cyano-2-methyl-benzamide; M.29.11.l) N-[5-[[2-bromo-6-chloro-4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]carbamoyl]-2-cyano-phenyl]-4-cyano-2-methyl-benzamide; M.29.11.m) N-[5-[[2-bromo-6-chloro-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]phenyl]carbamoyl]-2-cyano-phenyl]-4-cyano-2-methyl-benzamide; M.29.11.n) 4-cyano-N-[2-cyano-5-[[2,6-dichloro-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)-propyl]phenyl]carbamoyl]phenyl]-2-methyl-benzamide; M.29.11.o) 4-cyano-N-[2-cyano-5-[[2,6-dichloro-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]carbamoyl]phenyl]-2-methyl-benzamide; M.29.11.p) N-[5-[[2-bromo-6-chloro-4-[1,2,2,2-tetrafluoro-1-(trifluoro-methyl)ethyl]phenyl]carbamoyl]-2-cyano-phenyl]-4-cyano-2-methyl-benzamide; or

a compound selected from the of M.29.12, wherein the compound M.29.12a) to M.29.12m): M.29.12.a) 2-(1,3-Dioxan-2-yl)-6-[2-(3-pyridinyl)-5-thiazolyl]-pyridine; M.29.12.b) 2-[6-[2-(5-Fluoro-3-pyridinyl)-5-thiazolyl]-2-pyridinyl]-pyrimidine; M.29.12.c) 2-[6-[2-(3-Pyridinyl)-5-thiazolyl]-2-pyridinyl]-pyrimidine; M.29.12.d) N-Methylsulfonyl-6-[2-(3-pyridyl)thiazol-5-yl]pyridine-2-carboxamide; M.29.12.e) N-Methylsulfonyl-6-[2-(3-pyridyl)thiazol-5-yl]pyridine-2-carboxamide; M.29.12.f) N-Ethyl-N-[4-methyl-2-(3-pyridyl)thiazol-5-yl]-3-methylthio-propanamide; M.29.12.g) N-Methyl-N-[4-methyl-2-(3-pyridyl)thiazol-5-yl]-3-methylthio-propanamide; M.29.12.h) N,2-Dimethyl-N-[4-methyl-2-(3-pyridyl)thiazol-5-yl]-3-methylthio-propanamide; M.29.12.i) N-Ethyl-2-methyl-N-[4-methyl-2-(3-pyridyl)thiazol-5-yl]-3-methylthio-propanamide; M.29.12.j) N-[4-Chloro-2-(3-pyridyl)thiazol-5-yl]-N-ethyl-2-methyl-3-methylthio-propanamide; M.29.12.k) N-[4-Chloro-2-(3-pyridyl)thiazol-5-yl]-N,2-dimethyl-3-methylthio-propanamide; M.29.12.l) N-[4-Chloro-2-(3-pyridyl)thiazol-5-yl]-N-methyl-3-methylthio-propanamide; M.29.12.m) N-[4-Chloro-2-(3-pyridyl)thiazol-5-yl]-N-ethyl-3-methylthio-propanamide; or the compounds

M.29.14a) 1-[(6-Chloro-3-pyridinyl)methyl]-1,2,3,5,6,7-hexahydro-5-methoxy-7-methyl-8-nitro-imidazo[1,2-a]pyridine; or M.29.14b) 1-[(6-Chloropyridin-3-yl)methyl]-7-methyl-8-nitro-1,2,3,5,6,7-hexahydroimidazo[1,2-a]pyridin-5-ol; or the compounds

M.29.16a) 1-isopropyl-N,5-dimethyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; or M.29.16b) 1-(1,2-dimethylpropyl)-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; M.29.16c) N,5-dimethyl-N-pyridazin-4-yl-1-(2,2,2-trifluoro-1-methyl-ethyl)pyrazole-4-carboxamide; M.29.16d) 1-[1-(1-cyanocyclopropyl)ethyl]-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; M.29.16e) N-ethyl-1-(2-fluoro-1-methyl-propyl)-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; M.29.16f) 1-(1,2-dimethylpropyl)-N,5-dimethyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; M.29.16g) 1-[1-(1-cyanocyclopropyl)ethyl]-N,5-dimethyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; M.29.16h) N-methyl-1-(2-fluoro-1-methyl-propyl]-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; M.29.16i) 1-(4,4-difluorocyclohexyl)-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; or M.29.16j) 1-(4,4-difluoro-cyclohexyl)-N,5-dimethyl-N-pyridazin-4-yl-pyrazole-4-carboxamide, or

M.29.17 a compound selected from the compounds M.29.17a) to M.29.17j): M.29.17a) N-(1-methylethyl)-2-(3-pyridinyl)-2H-indazole-4-carboxamide; M.29.17b) N-cyclopropyl-2-(3-pyridinyl)-2H-indazole-4-carboxamide; M.29.17c) N-cyclohexyl-2-(3-pyridinyl)-2H-indazole-4-carboxamide; M.29.17d) 2-(3-pyridinyl)-N-(2,2,2-trifluoroethyl)-2H-indazole-4-carboxamide; M.29.17e) 2-(3-pyridinyl)-N-[(tetrahydro-2-furanyl)methyl]-2H-indazole-5-carboxamide; M.29.17f) methyl 2-[[2-(3-pyridinyl)-2H-indazol-5-yl]carbonyl]hydrazinecarboxylate; M.29.17g) N-[(2,2-difluorocyclopropyl)methyl]-2-(3-pyridinyl)-2H-indazole-5-carboxamide; M.29.17h) N-(2,2-difluoropropyl)-2-(3-pyridinyl)-2H-indazole-5-carboxamide; M.29.17i) 2-(3-pyridinyl)-N-(2-pyrimidinylmethyl)-2H-indazole-5-carboxamide; M.29.17j) N-[(5-methyl-2-pyrazinyl)methyl]-2-(3-pyridinyl)-2H-indazole-5-carboxamide, or

M.29.18 a compound selected from the compounds M.29.18a) to M.29.18d): M.29.18a) N-[3-chloro-1-(3-pyridyl)pyrazol-4-yl]-N-ethyl-3-(3,3,3-trifluoropropylsulfanyl)propanamide; M.29.18b) N-[3-chloro-1-(3-pyridyl)pyrazol-4-yl]-N-ethyl-3-(3,3,3-trifluoropropylsulfinyl)propanamide; M.29.18c) N-[3-chloro-1-(3-pyridyl)pyrazol-4-yl]-3-[(2,2-difluorocyclopropyl)methylsulfanyl]-N-ethyl-propanamide; M.29.18d) N-[3-chloro-1-(3-pyridyl)pyrazol-4-yl]-3-[(2,2-difluorocyclopropyl)methylsulfinyl]-N-ethyl-propanamide; or the compound

M.29.19 sarolaner, or the compound

M.29.20 lotilaner.

The commercially available compounds of the M listed above may be found in The Pesticide Manual, 16th Edition, C. MacBean, British Crop Protection Council (2013) among other publications. The online Pesticide Manual is updated regularly and is accessible through http://bcpcdata.com/pesticide-manual.html.

Another online data base for pesticides providing the ISO common names is http://www.alanwood.net/pesticides.

The M.4 neonicotinoid cycloxaprid is known from WO2010/069266 and WO2011/069456, the neonicotinoid M.4A.2, sometimes also to be named as guadipyr, is known from WO2013/003977, and the neonicotinoid M.4A.3 (approved as paichongding in China) is known from WO2007/101369. The metaflumizone analogue M.22B.1 is described in CN10171577 and the analogue M.22B.2 in CN102126994. The phthalamides M.28.1 and M.28.2 are both known from WO2007/101540. The anthranilamide M.28.3 is described in WO2005/077934. The hydrazide compound M.28.4 is described in WO2007/043677. The anthranilamides M.28.5a) to M.28.5d) and M.28.5h) are described in WO 2007/006670, WO2013/024009 and WO2013/024010, the anthranilamide M.28.5i) is described in WO2011/085575, M.28.5j) in WO2008/134969, M.28.5k) in US2011/046186 and M.28.5l) in WO2012/034403. The diamide compound M.28.6 can be found in WO2012/034472. The spiroketal-substituted cyclic ketoenol derivative M.29.3 is known from WO2006/089633 and the biphenyl-substituted spirocyclic ketoenol derivative M.29.4 from WO2008/067911. The triazoylphenylsulfide M.29.5 is described in WO2006/043635, and biological control agents on the basis of Bacillus firmus are described in WO2009/124707. The compounds M.29.6a) to M.29.6i) listed under M.29.6 are described in WO2012/029672, and M.29.6j) and M.29.6k) in WO2013/129688. The nematicide M.29.8 is known from WO2013/055584. The isoxazoline M.29.9.a) is described in WO2013/050317. The isoxazoline M.29.9.b) is described in WO2014/126208. The pyridalyl-type analogue M.29.10 is known from WO2010/060379. The carboxamides broflanilide and M.29.11.b) to M.29.11.h) are described in WO2010/018714, and the carboxamides M.29.11i) to M.29.11.p) in WO2010/127926. The pyridylthiazoles M.29.12.a) to M.29.12.C) are known from WO2010/006713, M.29.12.d) and M.29.12.e) are known from WO2012/000896, and M.29.12.f) to M.29.12.m) from WO2010/129497. The compounds M.29.14a) and M.29.14b) are known from WO2007/101369. The pyrazoles M.29.16.a) to M.29.16h) are described in WO2010/034737, WO2012/084670, and WO2012/143317, respectively, and the pyrazoles M.29.16i) and M.29.16j) are described in U.S. 61/891,437. The pyridinylindazoles M.29.17a) to M.29.17.j) are described in WO2015/038503. The pyridylpyrazoles M.29.18a) to M.29.18d) are described in US2014/0213448. The isoxazoline M.29.19 is described in WO2014/036056. The isoxazoline M.29.20 is known from WO2014/090918.

The following list of fungicides, in conjunction with which the compounds of the present invention can be used, is intended to illustrate the possible combinations but does not limit them:

A) Respiration inhibitors

-   -   Inhibitors of complex III at Q_(o) site (e. g. strobilurins):         azoxystrobin (A.1.1), coumethoxystrobin (A.1.2), coumoxystrobin         (A.1.3), dimoxystrobin (A.1.4), enestroburin (A.1.5),         fenaminstrobin (A.1.6), fenoxystrobin/flufenoxystrobin (A.1.7),         fluoxastrobin (A.1.8), kresoxim-methyl (A.1.9), mandestrobin         (A.1.10), metominostrobin (A.1.11), orysastrobin (A.1.12),         picoxy.strobin (A.1.13), pyraclostrobin (A.1.14),         pyrametostrobin (A.1.15), pyraoxystrobin (A.1.16),         trifloxystrobin (A.1.17),         2-(2-(3-(2,6-dichlorophenyl)-1-methyl-allylideneaminooxymethyl)-phenyl)-2-methoxyimino-N-methyl-acetamide         (A.1.18), pyribencarb (A.1.19), triclopyricarb/chlorodincarb         (A.1.20), famoxadone (A.1.21), fenamidone (A.1.21),         methyl-/V-[2-[(1,4-dimethyl-5-phenyl-pyrazol-3-yl)oxylmethyl]phenyl]-N-methoxy-carbamate         (A.1.22),         1-[3-chloro-2-[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxymethyl]phenyl]-4-methyl-tetrazol-5-one         (A.1.23),         1-[3-bromo-2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]phenyl]-4-methyl-tetrazol-5-one         (A.1.24),         1-[2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]-3-methyl-phenyl]-4-methyl-tetrazol-5-one         (A.1.25),         1-[2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]-3-fluoro-phenyl]-4-methyl-tetrazol-5-one         (A.1.26),         1-[2-[[1-(2,4-dichloro-phenyl)pyrazol-3-yl]oxymethyl]-3-fluoro-phenyl]-4-methyl-tetrazol-5-one         (A.1.27),         1-[2-[[4-(4-chlorophenyl)thiazol-2-yl]oxymethyl]-3-methyl-phenyl]-4-methyl-tetrazol-5-one         (A.1.28),         1-[3-chloro-2-[[4-(p-tolyl)thiazol-2-yl]oxymethyl]phenyl]-4-methyl-tetrazol-5-one         (A.1.29),         1-[3-cyclopropyl-2-[[2-methyl-4-(1-methylpyrazol-3-yl)phenoxy]methyl]phenyl]-4-methyl-tetrazol-5-one         (A.1.30),         1-[3-(difluoromethoxy)-2-[[2-methyl-4-(1-methylpyrazol-3-yl)phenoxy]methyl]phenyl]-4-methyl-tetrazol-5-one         (A.1.31),         1-methyl-4-[3-methyl-2-[[2-methyl-4-(1-methylpyrazol-3-yl)phenoxy]methyl]phenyl]tetrazol-5-one         (A.1.32),         1-methyl-4-[3-methyl-2-[[1-[3-(trifluoromethyl)phenyl]-ethylideneamino]oxymethyl]phenyl]tetrazol-5-one         (A.1.33),         (Z,2E)-5-[1-(2,4-dichlorophenyl)pyrazol-3-yl]oxy-2-methoxyimino-N,3-dimethyl-pent-3-enamide         (A.1.34),         (Z,2E)-5-[1-(4-chlorophenyl)pyrazol-3-yl]oxy-2-methoxyimino-N,3-dimethyl-pent-3-enamide         (A.1.35),         (Z,2E)-5-[1-(4-chloro-2-fluoro-phenyl)pyrazol-3-yl]oxy-2-methoxyimino-N,3-dimethyl-pent-3-enamide         (A.1.36),     -   inhibitors of complex III at Qi site: cyazofamid (A.2.1),         amisulbrom (A.2.2),         [(3S,6S,7R,8R)-8-benzyl-3-[(3-acetoxy-4-methoxy-pyridine-2-carbonyl)amino]-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl]         2-methylpropanoate (A.2.3),         [(3S,6S,7R,8R)-8-benzyl-3-[[3-(acetoxymethoxy)-4-methoxy-pyridine-2-carbonyl]amino]-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl]2-methylpropanoate         (A.2.4),         [(3S,6S,7R,8R)-8-benzyl-3-[(3-isobutoxycarbonyloxy-4-meth-oxy-pyridine-2-carbonyl)amino]-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl]         2-methylpropanoate (A.2.5),         [(3S,6S,7R,8R)-8-benzyl-3-[[3-(1,3-benzodioxol-5-ylmethoxy)-4-methoxy-pyridine-2-carbonyl]amino]-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl]         2-methylpropanoate (A.2.6);         (3S,6S,7R,8R)-3-[[(3-hydroxy-4-methoxy-2-pyridinyl)carbonyl]amino]-6-methyl-4,9-dioxo-8-(phenylmethyl)-1,5-dioxonan-7-yl         2-methylpropanoate (A.2.7),         (3S,6S,7R,8R)-8-benzyl-3-[3-[(isobutyryloxy)methoxy]-4-methoxypicolinamido]-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl         isobutyrate (A.2.8);     -   inhibitors of complex II (e. g. carboxamides): benodanil         (A.3.1), benzovindiflupyr (A.3.2), bixafen (A.3.3), boscalid         (A.3.4), carboxin (A.3.5), fenfuram (A.3.6), fluopyram (A.3.7),         flutolanil (A.3.8), fluxapyroxad (A.3.9), furametpyr (A.3.10),         isofetamid (A.3.11), iso-pyrazam (A.3.12), mepronil (A.3.13),         oxycarboxin (A.3.14), penflufen (A.3.14), penthiopyrad (A.3.15),         sedaxane (A.3.16), tecloftalam (A.3.17), thifluzamide (A.3.18),         N-(4′-trifluoromethylthiobiphenyl-2-yl)-3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxamide         (A.3.19),         N-(2-(1,3,3-trimethyl-butyl)-phenyl)-1,3-dimethyl-5-fluoro-1H-pyrazole-4-carboxamide         (A.3.20),         3-(difluoromethyl)-1-methyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide         (A.3.21),         3-(trifluoromethyl)-1-methyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide         (A.3.22),         1,3-dimethyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide         (A.3.23),         3-(trifluoromethyl)-1,5-dimethyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide         (A.3.24),         1,3,5-trimethyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide         (A.3.25),         N-(7-fluoro-1,1,3-trimethyl-indan-4-yl)-1,3-dimethyl-pyrazole-4-carboxamide         (A.3.26),         N-[2-(2,4-dichlorophenyl)-2-methoxy-1-methyl-ethyl]-3-(difluoromethyl)-1-methyl-pyrazole-4-carboxamide         (A.3.27);     -   other respiration inhibitors (e. g. complex I, uncouplers):         diflumetorim (A.4.1),         (5,8-difluoroquinazolin-4-yl)-{2-[2-fluoro-4-(4-trifluoromethylpyridin-2-yloxy)-phenyl]-ethyl}-amine         (A.4.2); nitrophenyl derivates: binapacryl (A.4.3), dinobuton         (A.4.4), dinocap (A.4.5), fluazinam (A.4.6); ferimzone (A.4.7);         organometal compounds: fentin salts, such as fentin-acetate         (A.4.8), fentin chloride (A.4.9) or fentin hydroxide (A.4.10);         ametoctradin (A.4.11); and silthiofam (A.4.12);

B) Sterol biosynthesis inhibitors (SBI fungicides)

-   -   C14 demethylase inhibitors (DMI fungicides): triazoles:         azaconazole (B.1.1), bitertanol (B.1.2), bromuconazole (B.1.3),         cyproconazole (B.1.4), difenoconazole (B.1.5), diniconazole         (B.1.6), diniconazole-M (B.1.7), epoxiconazole (B.1.8),         fenbuconazole (B.1.9), fluquinconazole (B.1.10), flusilazole         (B.1.11), flutriafol (B.1.12), hexaconazole (B.1.13),         imibenconazole (B.1.14), ipconazole (B.1.15), metconazole         (B.1.17), myclobutanil (B.1.18), oxpoconazole (B.1.19),         paclobutrazole (B.1.20), penconazole (B.1.21), propiconazole         (B.1.22), prothioconazole (B.1.23), simeconazole (B.1.24),         tebuconazole (B.1.25), tetraconazole (B.1.26), triadimefon         (B.1.27), triadimenol (B.1.28), triticonazole (B.1.29),         uniconazole (B.1.30),         1-[rel-(2S;3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)-oxiranylmethyl]-5-thiocyanato-1H-[1,2,4]triazolo         (B.1.31),         2-[rel-(2S;3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)-oxiranylmethyl]-2H-[1,2,4]triazole-3-thiol         (B.1.32),         2-[2-chloro-4-(4-chlorophenoxy)phenyl]-1-(1,2,4-triazol-1-yl)pentan-2-ol         (B.1.33),         1-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-cyclopropyl-2-(1,2,4-triazol-1-yl)ethanol         (B.1.34),         2-[4-(4-chloro-phenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)butan-2-ol         (B.1.35),         2-[2-chloro-4-(4-chlorophenoxy)phenyl]-1-(1,2,4-triazol-1-yl)butan-2-ol         (B.1.36),         2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-3-methyl-1-(1,2,4-triazol-1-yl)butan-2-ol         (B.1.37),         2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol         (B.1.38),         2-[2-chloro-4-(4-chlorophenoxy)phenyl]-3-methyl-1-(1,2,4-triazol-1-yl)butan-2-ol         (B.1.39),         2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)pentan-2-ol         (B.1.40),         2-[4-(4-fluorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol         (B.1.41),         2-[2-chloro-4-(4-chlorophenoxy)phenyl]-1-(1,2,4-triazol-1-yl)pent-3-yn-2-ol         (B.1.51); imidazoles: imazalil (B.1.42), pefurazoate (B.1.43),         prochloraz (B.1.44), triflumizol (B.1.45); pyrimidines,         pyridines and piperazines: fenarimol (B.1.46), nuarimol         (B.1.47), pyrifenox (B.1.48), triforine (B.1.49),         [3-(4-chloro-2-fluoro-phenyl)-5-(2,4-difluorophenyl)isoxazol-4-yl]-(3-pyridyl)methanol         (B.1.50);     -   Delta14-reductase inhibitors: aldimorph (B.2.1), dodemorph         (B.2.2), dodemorph-acetate (B.2.3), fenpropimorph (B.2.4),         tridemorph (B.2.5), fenpropidin (B.2.6), piperalin (B.2.7),         spiroxamine (B.2.8);     -   Inhibitors of 3-keto reductase: fenhexamid (B.3.1);

C) Nucleic acid synthesis inhibitors

-   -   phenylamides or acyl amino acid fungicides: benalaxyl (C.1.1),         benalaxyl-M (C.1.2), kiralaxyl (C.1.3), metalaxyl (C.1.4),         metalaxyl-M (mefenoxam, C.1.5), ofurace (C.1.6), oxadixyl         (C.1.7);     -   others: hymexazole (C.2.1), octhilinone (C.2.2), oxolinic acid         (C.2.3), bupirimate (C.2.4), 5-fluorocytosine (C.2.5),         5-fluoro-2-(p-tolylmethoxy)pyrimidin-4-amine (C.2.6),         5-fluoro-2-(4-fluorophenylmethoxy)pyrimidin-4-amine (C.2.7);

D) Inhibitors of cell division and cytoskeleton

-   -   tubulin inhibitors, such as benzimidazoles, thiophanates:         benomyl (D1.1), carbendazim (D1.2), fuberidazole (D1.3),         thiabendazole (D1.4), thiophanate-methyl (D1.5);         triazolopyrimidines:         5-chloro-7-(4-methylpiperidin-1-yl)-6-(2,4,6-trifluorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidine         (D1.6);     -   other cell division inhibitors: diethofencarb (D2.1), ethaboxam         (D2.2), pencycuron (D2.3), fluopicolide (D2.4), zoxamide (D2.5),         metrafenone (D2.6), pyriofenone (D2.7); E) Inhibitors of amino         acid and protein synthesis methionine synthesis inhibitors         (anilino-pyrimidines): cyprodinil (E.1.1), mepanipyrim (E.1.2),         pyrimethanil (E.1.3);     -   protein synthesis inhibitors: blasticidin-S (E.2.1), kasugamycin         (E.2.2), kasugamycin hydrochloride-hydrate (E.2.3), mildiomycin         (E.2.4), streptomycin (E.2.5), oxytetracyclin (E.2.6), polyoxine         (E.2.7), validamycin A (E.2.8);

F) Signal transduction inhibitors

-   -   MAP/histidine kinase inhibitors: fluoroimid (F.1.1), iprodione         (F.1.2), procymidone (F.1.3), vinclozolin (F.1.4), fenpiclonil         (F.1.5), fludioxonil (F.1.6);     -   G protein inhibitors: quinoxyfen (F.2.1);

G) Lipid and membrane synthesis inhibitors

-   -   Phospholipid biosynthesis inhibitors: edifenphos (G.1.1),         iprobenfos (G.1.2), pyrazophos (G.1.3), isoprothiolane (G.1.4);     -   lipid peroxidation: dicloran (G.2.1), quintozene (G.2.2),         tecnazene (G.2.3), tolclofos-methyl (G.2.4), biphenyl (G.2.5),         chloroneb (G.2.6), etridiazole (G.2.7);     -   phospholipid biosynthesis and cell wall deposition: dimethomorph         (G.3.1), flumorph (G.3.2), mandipropamid (G.3.3), pyrimorph         (G.3.4), benthiavalicarb (G.3.5), iprovalicarb (G.3.6),         valifenalate (G.3.7) and         N-(1-(1-(4-cyano-phenyl)ethanesulfonyl)-but-2-yl) carbamic         acid-(4-fluorophenyl) ester (G.3.8);     -   compounds affecting cell membrane permeability and fatty acides:         propamocarb (G.4.1);     -   fatty acid amide hydrolase inhibitors: oxathiapiprolin (G.5.1),         2-{3-[2-(1-{[3,5-bis(di-fluoromethyl-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}phenyl         methanesulfonate (G.5.2),         2-{3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)         1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenyl         methanesulfonate (G.5.3);

H) Inhibitors with Multi Site Action

-   -   inorganic active substances: Bordeaux mixture (H.1.1), copper         acetate (H.1.2), copper hydroxide (H.1.3), copper oxychloride         (H.1.4), basic copper sulfate (H.1.5), sulfur (H.1.6);     -   thio- and dithiocarbamates: ferbam (H.2.1), mancozeb (H.2.2),         maneb (H.2.3), metam (H.2.4), metiram (H.2.5), propineb (H.2.6),         thiram (H.2.7), zineb (H.2.8), ziram (H.2.9);     -   organochlorine compounds (e. g. phthalimides, sulfamides,         chloronitriles): anilazine (H.3.1), chlorothalonil (H.3.2),         captafol (H.3.3), captan (H.3.4), folpet (H.3.5), dichlofluanid         (H.3.6), dichlorophen (H.3.7), hexachlorobenzene (H.3.8),         pentachlorphenole (H.3.9) and its salts, phthalide (H.3.10),         tolylfluanid (H.3.11),         N-(4-chloro-2-nitro-phenyl)-N-ethyl-4-methyl-benzenesulfonamide         (H.3.12);     -   guanidines and others: guanidine (H.4.1), dodine (H.4.2), dodine         free base (H.4.3), guazatine (H.4.4), guazatine-acetate (H.4.5),         iminoctadine (H.4.6), iminoctadine-triacetate (H.4.7),         iminoctadine-tris(albesilate) (H.4.8), dithianon (H.4.9),         2,6-dimethyl-1H,5H-[1,4]dithiino[2,3-c:5,6-c′]dipyrrole-1,3,5,7(2H,6H)-tetraone         (H.4.10);

I) Cell wall synthesis inhibitors

-   -   inhibitors of glucan synthesis: validamycin (1.1.1), polyoxin B         (1.1.2);     -   melanin synthesis inhibitors: pyroquilon (1.2.1), tricyclazole         (1.2.2), carpropamid (I.2.3), dicyclomet (I.2.4), fenoxanil         (1.2.5);

J) Plant defence inducers

-   -   acibenzolar-S-methyl (J.1.1), probenazole (J.1.2), isotianil         (J.1.3), tiadinil (J.1.4), prohexadione-calcium (J.1.5);         phosphonates: fosetyl (J.1.6), fosetyl-aluminum (J.1.7),         phosphorous acid and its salts (J.1.8), potassium or sodium         bicarbonate (J.1.9);

K) Unknown mode of action

-   -   bronopol (K.1.1), chinomethionat (K.1.2), cyflufenamid (K.1.3),         cymoxanil (K.1.4), dazomet (K.1.5), debacarb (K.1.6),         diclomezine (K.1.7), difenzoquat (K.1.8),         difenzoquat-methylsulfate (K.1.9), diphenylamin (K.1.10),         fenpyrazamine (K.1.11), flumetover (K.1.12), flusulfamide         (K.1.13), flutianil (K. 1.14), methasulfocarb (K.1.15),         nitrapyrin (K.1.16), nitrothal-isopropyl (K.1.18),         oxathiapiprolin (K.1.19), tolprocarb (K.1.20), oxin-copper         (K.1.21), proquinazid (K.1.22), tebufloquin (K.1.23),         tecloftalam (K.1.24), triazoxide (K.1.25),         2-butoxy-6-iodo-3-propylchromen-4-one (K.1.26),         2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]-1-[4-(4-{5-[2-(prop-2-yn-1-yloxy)phenyl]-4,5-dihydro-1,2-oxazol-3-yl}-1,3-thiazol-2-yl)piperidin-1-yl]ethanone         (K.1.27),         2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]-1-[4-(4-{5-[2-fluoro-6-(prop-2-yn-1-yloxy)phenyl]-4,5-dihydro-1,2-oxazol-3-yl}-1,3-thiazol-2-yl)piperidin-1-yl]ethanone         (K.1.28),         2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]-1-[4-(4-{5-[2-chloro-6-(prop-2-yn-1-yloxy)phenyl]-4,5-dihydro-1,2-oxazol-3-yl}-1,3-thiazol-2-yl)piperidin-1-yl]ethanone         (K.1.29),         N-(cyclo-propylmethoxyimino-(6-difluoro-methoxy-2,3-difluoro-phenyl)-methyl)-2-phenyl         acetamide (K.1.30),         N′-(4-(4-chloro-3-trifluoromethyl-phenoxy)-2,5-dimethyl-phenyl)-N-ethyl-N-methyl         formamidine (K. 1.31),         N′-(4-(4-fluoro-3-trifluoromethyl-phenoxy)-2,5-dimethyl-phenyl)-N-ethyl-N-methyl         formamidine (K.1.32),         N′-(2-methyl-5-trifluoromethyl-4-(3-trimethylsilanyl-prop-oxy)-phenyl)-N-ethyl-N-methyl         formamidine (K.1.33),         N′-(5-difluoromethyl-2-methyl-4-(3-tri-methylsilanyl-propoxy)-phenyl)-N-ethyl-N-methyl         formamidine (K.1.34), methoxy-acetic acid         6-tert-butyl-8-fluoro-2,3-dimethyl-quinolin-4-yl ester (K.1.35),         3-[5-(4-methylphenyl)-2,3-dimethyl-isoxazolidin-3-yl]-pyridine         (K.1.36),         3-[5-(4-chloro-phenyl)-2,3-dimethyl-isoxazolidin-3-yl]-pyridine         (pyrisoxazole) (K.1.37), N-(6-methoxy-pyridin-3-yl)         cyclopropanecarboxylic acid amide (K.1.38),         5-chloro-1-(4,6-dimethoxy-pyrimidin-2-yl)-2-methyl-1H-benzoimidazole         (K.1.39),         2-(4-chloro-phenyl)-N-[4-(3,4-dimethoxy-phenyl)-isoxazol-5-yl]-2-prop-2-ynyloxy-acetamide,         ethyl (Z)-3-amino-2-cyano-3-phenyl-prop-2-enoate (K.1.40),         picarbutrazox (K.1.41), pentyl         N-[6-[[(Z)-[(1-methyltetrazol-5-yl)-phenyl-methylene]amino]oxymethyl]-2-pyridyl]carbamate         (K.1.42),         2-[2-[(7,8-difluoro-2-methyl-3-quinolyl)oxy]-6-fluoro-phenyl]propan-2-ol         (K.1.43),         2-[2-fluoro-6-[(8-fluoro-2-methyl-3-quinolyl)oxy]phen-yl]propan-2-ol         (K.1.44),         3-(5-fluoro-3,3,4,4-tetramethyl-3,4-dihydroisoquinolin-1-yl)quinoline         (K.1.45),         3-(4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)quinoline         (K.1.46),         3-(4,4,5-trifluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)quinoline         (K.1.47),         9-fluoro-2,2-dimethyl-5-(3-quinolyl)-3H-1,4-benzoxazepine         (K.1.48).

The fungicides described by common names, their preparation and their activity e.g. against harmful fungi is known (cf.: http://www.alanwood.net/pesticides/); these substances are commercially available.

The fungicides described by IUPAC nomenclature, their preparation and their pesticidal activity is also known (cf. Can. J. Plant Sci. 48(6), 587-94, 1968; EP-A 141 317; EP-A 152 031; EP-A 226 917; EP-A 243 970; EP-A 256 503; EP-A 428 941; EP-A 532 022; EP-A 1 028 125; EP-A 1 035 122; EP-A 1 201 648; EP-A 1 122 244, JP 2002316902; DE 19650197; DE 10021412; DE 102005009458; U.S. Pat. Nos. 3,296,272; 3,325,503; WO 98/46608; WO 99/14187; WO 99/24413; WO 99/27783; WO 00/29404; WO 00/46148; WO 00/65913; WO 01/54501; WO 01/56358; WO 02/22583; WO 02/40431; WO 03/10149; WO 03/11853; WO 03/14103; WO 03/16286; WO 03/53145; WO 03/61388; WO 03/66609; WO 03/74491; WO 04/49804; WO 04/83193; WO 05/120234; WO 05/123689; WO 05/123690; WO 05/63721; WO 05/87772; WO 05/87773; WO 06/15866; WO 06/87325; WO 06/87343; WO 07/82098; WO 07/90624, WO 11/028657, WO2012/168188, WO 2007/006670, WO 2011/77514; WO13/047749, WO 10/069882, WO 13/047441, WO 03/16303, WO 09/90181, WO 13/007767, WO 13/010862, WO 13/127704, WO 13/024009, WO 13/024010 and WO 13/047441, WO 13/162072, WO 13/092224, WO 11/135833).

Biopesticides

Suitable mixing partners for the compounds of the present invention also include biopesticides.

Biopesticides have been defined as a form of pesticides based on micro-organisms (bacteria, fungi, viruses, nematodes, etc.) or natural products (compounds, such as metabolites, proteins, or extracts from biological or other natural sources) (U.S. Environmental Protection Agency: http://www.epa.gov/pesticides/biopesticides/). Biopesticides fall into two major classes, microbial and biochemical pesticides:

(1) Microbial pesticides consist of bacteria, fungi or viruses (and often include the metabolites that bacteria and fungi produce). Entomopathogenic nematodes are also classified as microbial pesticides, even though they are multi-cellular.

(2) Biochemical pesticides are naturally occurring substances or or structurally-similar and functionally identical to a naturally-occurring substance and extracts from biological sources that control pests or provide other crop protection uses as defined below, but have non-toxic mode of actions (such as growth or developmental regulation, attractents, repellents or defence activators (e.g. induced resistance) and are relatively non-toxic to mammals.

Biopesticides for use against crop diseases have already established themselves on a variety of crops. For example, biopesticides already play an important role in controlling downy mildew diseases. Their benefits include: a 0-Day Pre-Harvest Interval, the ability to use under moderate to severe disease pressure, and the ability to use in mixture or in a rotational program with other registered pesticides.

A major growth area for biopesticides is in the area of seed treatments and soil amendments. Biopesticidal seed treatments are e.g. used to control soil borne fungal pathogens that cause seed rots, damping-off, root rot and seedling blights. They can also be used to control internal seed borne fungal pathogens as well as fungal pathogens that are on the surface of the seed. Many biopesticidal products also show capacities to stimulate plant host defenses and other physiological processes that can make treated crops more resistant to a variety of biotic and abiotic stresses or can regulate plant growth. Many biopesticidal products also show capacities to stimulate plant health, plant growth and/or yield enhancing activity.

The following list of biopesticides, in conjunction with which the compounds of the present invention can be used, is intended to illustrate the possible combinations but does not limit them:

L) Biopesticides

L1) Microbial pesticides with fungicidal, bactericidal, viricidal and/or plant defense activator activity: Ampeiomyces quisqualis, Aspergillus flavus, Aureobasidium pullulans, Bacillus altitudinis, B. amyloliquefaciens, B. megaterium, B. mojavensis, B. mycoides, B. pumilus, B. simplex, B. solisalsi, B. subtilis, B. subtilis var. amyloliquefaciens, Candida oleophila, C. saitoana, Clavibacter michiganensis (bacteriophages), Coniothyrium minitans, Cryphonectria parasitica, Cryptococcus albidus, Dilophosphora alopecuri, Fusarium oxysporum, Clonostachys rosea f. catenulate (also named Gliocladium catenulatum), Gliocladium roseum, Lysobacter antibioticus, L. enzymogenes, Metschnikowia fructicola, Microdochium dimerum, Microsphaeropsis ochracea, Muscodor albus, Paenibacillus alvei, Paenibacillus polymyxa, Pantoea vagans, Penicillium bilaiae, Phlebiopsis gigantea, Pseudomonas sp., Pseudomonas chloraphis, Pseudozyma flocculosa, Pichia anomala, Pythium oligandrum, Sphaerodes mycoparasitica, Streptomyces griseoviridis, S. lydicus, S. violaceusniger, Talaromyces flavus, Trichoderma asperelloides, T. asperellum, T. atroviride, T. fertile, T. gamsii, T. harmatum, T. harzianum, T. polysporum, T. stromaticum, T. virens, T. viride, Typhula phacorrhiza, Ulocladium oudemansii, Verticillium dahlia, zucchini yellow mosaic virus (avirulent strain);

L2) Biochemical pesticides with fungicidal, bactericidal, viricidal and/or plant defense activator activity: harpin protein, Reynoutria sachalinensis extract;

L3) Microbial pesticides with insecticidal, acaricidal, molluscidal and/or nematicidal activity: Agrobacterium radiobacter, Bacillus cereus, B. firmus, B. thuringiensis, B. thuringiensis ssp. aizawai, B. t. ssp. israelensis, B. t. ssp. galleriae, B. t. ssp. kurstaki, B. t. ssp. tenebrionis, Beauveria bassiana, B. brongniartii, Burkholderia spp., Chromobacterium subtsugae, Cydia pomonella granulovirus (CpGV), Cryptophlebia leucotreta granulovirus (CrleGV), Flavobacterium spp., Helicoverpa armigera nucleopolyhedrovirus (HearNPV), Helicoverpa zea nucleopolyhedrovirus (HzNPV), Helicoverpa zea single capsid nucleopolyhedrovirus (HzSNPV), Heterorhabditis bacteriophora, Isaria fumosorosea, Lecanicillium longisporum, L. muscarium, Metarhizium anisopliae, Metarhizium anisopliae var. anisopliae, M. anisopliae var. acridum, Nomuraea rileyi, Paecilomyces fumosoroseus, P. lilacinus, Paenibacillus popilliae, Pasteuria spp., P. nishizawae, P. penetrans, P. ramosa, P. thornea, P. usgae, Pseudomonas fluorescens, Spodoptera littoralis nucleopolyhedrovirus (SpliNPV), Steinernema carpocapsae, S. feltiae, S. kraussei, Streptomyces galbus, S. microflavus;

L4) Biochemical pesticides with insecticidal, acaricidal, molluscidal, pheromone and/or nematicidal activity: L-carvone, citral, (E,Z)-7,9-dodecadien-1-yl acetate, ethyl formate, (E,Z)-2,4-ethyl decadienoate (pear ester), (Z,Z,E)-7,11,13-hexadecatrienal, heptyl butyrate, isopropyl myristate, lavanulyl senecioate, cis-jasmone, 2-methyl 1-butanol, methyl eugenol, methyl jasmonate, (E,Z)-2,13-octadecadien-1-ol, (E,Z)-2,13-octadecadien-1-ol acetate, (E,Z)-3,13-octadecadien-1-ol, R-1-octen-3-ol, pentatermanone, (E,Z,Z)-3,8,11-tetradecatrienyl acetate, (Z,E)-9,12-tetradecadien-1-yl acetate, Z-7-tetradecen-2-one, Z-9-tetradecen-1-yl acetate, Z-11-tetradecenal, Z-11-tetradecen-1-ol, extract of Chenopodium ambrosiodes, Neem oil, Quillay extract;

L5) Microbial pesticides with plant stress reducing, plant growth regulator, plant growth promoting and/or yield enhancing activity: Azospirillum amazonense, A. brasiiense, A. lipoferum, A. irakense, A. haiopraeferens, Bradyrhizobium spp., B. elkanii, B. japonicum, B. liaoningense, B. lupini, Delftia addovorans, Glomus intraradices, Mesorhizobium spp., Rhizobium leguminosarum bv. phaseoli, R. l. bv. trifolii, R. l. bv. viciae, R. tropici, Sinorhizobium meliloti.

The biopesticides from L1) and/or L2) may also have insecticidal, acaricidal, molluscidal, pheromone, nematicidal, plant stress reducing, plant growth regulator, plant growth promoting and/or yield enhancing activity. The biopesticides from L3) and/or L4) may also have fungicidal, bactericidal, viricidal, plant defense activator, plant stress reducing, plant growth regulator, plant growth promoting and/or yield enhancing activity. The biopesticides from L5) may also have fungicidal, bactericidal, viricidal, plant defense activator, insecticidal, acaricidal, molluscidal, pheromone and/or nematicidal activity.

Many of these biopesticides have been deposited under deposition numbers mentioned herein (the prefices such as ATCC or DSM refer to the acronym of the respective culture collection, for details see e. g. here: http://www.wfcc.info/ccinfo/collection/bv acronym/), are referred to in literature, registered and/or are commercially available: mixtures of Aureobasidium pullulans DSM 14940 and DSM 14941 isolated in 1989 in Konstanz, Germany (e. g. blastospores in Blossom Protect® from bio-ferm GmbH, Austria), Azospirillum brasiiense Sp245 originally isolated in wheat reagion of South Brazil (Passo Fundo) at least prior to 1980 (BR 11005; e. g. GELFIX® Grarmneas from BASF Agricultural Specialties Ltd., Brazil), A. brasiiense strains Ab-V5 and Ab-V6 (e. g. in AzoMax from Novozymes BioAg Produtos papra Agricultura Ltda., Quattro Barras, Brazil or Simbiose-Maiz® from Simbiose-Agro, Brazil; Plant Soil 331, 413-425, 2010), Bacillus amyloliquefaciens strain AP-188 (NRRL B-50615 and B-50331; U.S. Pat. No. 8,445,255); B. amyloliquefaciens spp. plantarum D747 isolated from air in Kikugawa-shi, Japan (US 20130236522 A1; FERM BP-8234; e. g. Double Nickel™ 55 WDG from Certis LLC, USA), B. amyloliquefaciens spp. piantarum FZB24 isolated from soil in Brandenburg, Germany (also called SB3615; DSM 96-2; J. Plant Dis. Prot. 105, 181-197, 1998; e. g. Taegro® from Novozyme Biologicals, Inc., USA), B. amyloliquefaciens ssp. piantarum FZB42 isolated from soil in Brandenburg, Germany (DSM 23117; J. Plant Dis. Prot. 105, 181-197, 1998; e. g. RhizoVital® 42 from AbiTEP GmbH, Germany), B. amyloliquefaciens ssp. plantarum MBI600 isolated from faba bean in Sutton Bonington, Nottinghamshire, U.K. at least before 1988 (also called 1430; NRRL B-50595; US 2012/0149571 A1; e. g. Integral® from BASF Corp., USA), B. amyloliquefaciens spp. plantarum QST-713 isolated from peach orchard in 1995 in California, U.S.A. (NRRL B-21661; e. g. Serenade® MAX from Bayer Crop Science LP, USA), B. amyloliquefaciens spp. plantarum TJ1000 isolated in 1992 in South Dakoda, U.S.A. (also called 1BE; ATCC BAA-390; CA 2471555 A1; e. g. QuickRoots™ from TJ Technologies, Watertown, S. Dak., USA), B. firmus CNCM I-1582, a variant of parental strain EIP-N1 (CNCM I-1556) isolated from soil of central plain area of Israel (WO 2009/126473, U.S. Pat. No. 6,406,690; e. g. Votivo® from Bayer CropScience LP, USA), B. pumilus GHA 180 isolated from apple tree rhizosphere in Mexico (IDAC 260707-01; e. g. PRO-MIX® BXfrom Premier Horticulture, Quebec, Canada), B. pumilus INR-7 otherwise referred to as BU-F₂₂ and BU-F₃₃ isolated at least before 1993 from cucumber infested by Erwinia tracheiphila (NRRL B-50185, NRRL B-50153; U.S. Pat. No. 8,445,255), B. pumilus QST 2808 was isolated from soil collected in Pohnpei, Federated States of Micronesia, in 1998 (NRRL B-30087; e. g. Sonata® or Ballad® Plus from Bayer Crop Science LP, USA), B. simplex ABU 288 (NRRL B-50304; U.S. Pat. No. 8,445,255), B. subtilis FB17 also called UD 1022 or UD10-22 isolated from red beet roots in North America (ATCC PTA-11857; System. Appl. Microbiol. 27, 372-379, 2004; US 2010/0260735; WO 2011/109395); B. thuringiensis ssp. aizawai ABTS-1857 isolated from soil taken from a lawn in Ephraim, Wis., U.S.A., in 1987 (also called ABG-6346; ATCC SD-1372; e. g. XenTari® from BioFa AG, Münsingen, Germany), B. t. ssp. kurstaki ABTS-351 identical to HD-1 isolated in 1967 from diseased Pink Bollworm black larvae in Brownsville, Tex., U.S.A. (ATCC SD-1275; e. g. Dipel® DF from Valent BioSciences, IL, USA), B. t. ssp. tenebrionis NB-176-1, a mutant of strain NB-125, a wild type strain isolated in 1982 from a dead pupa of the beetle Tenebrio molitor(DSM 5480; EP 585 215 B1; e. g. Novodor® from Valent BioSciences, Switzerland), Beauveria bassiana GHA (ATCC 74250; e. g. BotaniGard® 22WGP from Laverlam Int. Corp., USA), B. bassiana JW-1 (ATCC 74040; e. g. Naturalis® from CBC (Europe) S.r.l., Italy), Bradyrhizobium elkanii strains SEMIA 5019 (also called 29W) isolated in Rio de Janeiro, Brazil and SEMIA 587 isolated in 1967 in the State of Rio Grande do Sul, from an area previously inoculated with a North American isolate, and used in commercial inoculants since 1968 (Appl. Environ. Microbiol. 73(8), 2635, 2007; e. g. GELFIX 5 from BASF Agricultural Specialties Ltd., Brazil), B. japonicum 532c isolated from Wisconsin field in U.S.A. (Nitragin 61A152; Can. J. Plant. Sci. 70, 661-666, 1990; e. g. in Rhizoflo®, Histick®, Hicoat® Super from BASF Agricultural Specialties Ltd., Canada), B. japonicum E-109 variant of strain USDA 138 (INTA E109, SEMIA 5085; Eur. J. Soil Biol. 45, 28-35, 2009; Biol. Fertil. Soils 47, 81-89, 2011); B. japonicum strains deposited at SEMIA known from Appl. Environ. Microbiol. 73(8), 2635, 2007: SEMIA 5079 isolated from soil in Cerrados region, Brazil by Embrapa-Cerrados used in commercial inoculants since 1992 (CPAC 15; e. g. GELFIX 5 or ADHERE 60 from BASF Agricultural Specialties Ltd., Brazil), B. japonicum SEMIA 5080 obtained under lab condtions by Embrapa-Cerrados in Brazil and used in commercial inoculants since 1992, being a natural variant of SEMIA 586 (CB1809) originally isolated in U.S.A. (CPAC 7; e. g. GELFIX 5 or ADHERE 60 from BASF Agricultural Specialties Ltd., Brazil); Burkholderia sp. A396 isolated from soil in Nikko, Japan, in 2008 (NRRL B-50319; WO 2013/032693; Marrone Bio Innovations, Inc., USA), Coniothyrium minitans CON/M/91-08 isolated from oilseed rape (WO 1996/021358; DSM 9660; e. g. Contans® WG, Intercept® WG from Bayer CropScience AG, Germany), harpin (alpha-beta) protein (Science 257, 85-88, 1992; e. g. Messenger™ or HARP—N-Tek from Plant Health Care pic, U.K.), Helicoverpa armigera nucleopolyhedrovirus (HearNPV) (J. Invertebrate Pathol. 107, 112-126, 2011; e. g. Helicovex® from Adermatt Biocontrol, Switzerland; Diplomata® from Koppert, Brazil; Vivus® Max from AgBiTech Pty Ltd., Queensland, Australia), Helicoverpa zea single capsid nucleopolyhedrovirus (HzSNPV) (e. g. Gemstar® from Certis LLC, USA), Helicoverpa zea nucleopolyhedrovirus ABA-NPV-U (e. g. Heligen® from AgBiTech Pty Ltd., Queensland, Australia), Heterorhabditis bacteriophora (e. g. Nemasys® G from BASF Agricultural Specialities Limited, UK), Isaria fumosorosea Apopka-97 isolated from mealy bug on gynura in Apopka, Fla., U.S.A. (ATCC 20874; Biocontrol Science Technol. 22(7), 747-761, 2012; e. g. PFR-97™ or PreFeRal® from Certis LLC, USA), Metarhizium anisopliae var. anisopliae F₅₂ also called 275 or V275 isolated from codling moth in Austria (DSM 3884, ATCC 90448; e. g. Met52® Novozymes Biologicals BioAg Group, Canada), Metschnikowia fructicola 277 isolated from grapes in the central part of Israel (U.S. Pat. No. 6,994,849; NRRL Y-30752; e. g. formerly Shemer® from Agrogreen, Israel), Paecilomyces ilacinus 251 isolated from infected nematode eggs in the Philippines (AGAL 89/030550; WO1991/02051; Crop Protection 27, 352-361, 2008; e. g. BioAct® from Bayer CropScience AG, Germany and MeloCon® from Certis, USA), Pasteuria nishizawae Pn1 isolated from a soybean field in the mid-2000s in Illinois, U.S.A. (ATCC SD-5833; Federal Register 76(22), 5808, Feb. 2, 2011; e.g. Clariva™ PN from Syngenta Crop Protection, LLC, USA), Penicillium bilaiae (also called P. bilaii) strains ATCC 18309 (=ATCC 74319), ATCC 20851 and/or ATCC 22348 (=ATCC 74318) originally isolated from soil in Alberta, Canada (Fertilizer Res. 39, 97-103, 1994; Can. J. Plant Sci. 78(1), 91-102, 1998; U.S. Pat. No. 5,026,417, WO 1995/017806; e. g. Jump Start®, Provide® from Novozymes Biologicals BioAg Group, Canada), Reynoutria sachalinensis extract (EP 0307510 B1; e. g. Regalia® SC from Marrone Bioinnovations, Davis, Calif., USA or Milsana® from BioFa AG, Germany), Steinernema carpocapsae (e. g. Millenium® from BASF Agricultural Specialities Limited, UK), S. feltiae (e. g. Nemashield® from BioWorks, Inc., USA; Nemasys® from BASF Agricultural Specialities Limited, UK), Streptomyces microflavus NRRL B-50550 (WO 2014/124369; Bayer CropScience, Germany), T. harzianum T-22 also called KRL-AG2 (ATCC 20847; BioControl 57, 687-696, 2012; e. g. Plantshield® from BioWorks Inc., USA or SabrEx™ from Advanced Biological Marketing Inc., Van Wert, Ohio, USA).

According to the invention, the solid material (dry matter) of the biopesticides (with the exception of oils such as Neem oil) are considered as active components (e.g. to be obtained after drying or evaporation of the extraction or suspension medium in case of liquid formulations of the microbial pesticides).

In accordance with the present invention, the weight ratios and percentages used herein for a biological extract such as Quillay extract are based on the total weight of the dry content (solid material) of the respective extract(s).

The total weight ratios of compositions comprising at least one microbial pesticide in the form of viable microbial cells including dormant forms, can be determined using the amount of CFU of the respective microorganism to calculate the total weight of the respective active component with the following equation that 1×10¹⁰ CFU equals one gram of total weight of the respective active component. Colony forming unit is measure of viable microbial cells, in particular fungal and bacterial cells. In addition, here “CFU” may also be understood as the number of (juvenile) individual nematodes in case of (entomopathogenic) nematode biopesticides, such as Steinernema feltiae.

When mixtures comprising microbial pesticides are employed in crop protection, the application rates preferably range from about 1×106 to 5×1015 (or more) CFU/ha, preferably from about 1×108 to about 1×1013 CFU/ha, and even more preferably from about 1×109 to about 1×1012 CFU/ha. In the case of (entomopathogenic) nematodes as microbial pesticides (e. g. Steinernema feltiae), the application rates preferably range inform about 1×105 to 1×1012 (or more), more preferably from 1×108 to 1×1011, even more preferably from 5×108 to 1×1010 individuals (e. g. in the form of eggs, juvenile or any other live stages, preferably in an infetive juvenile stage) per ha.

When mixtures comprising microbial pesticides are employed in seed treatment, the application rates with respect to plant propagation material preferably range from about 1×106 to 1×1012 (or more) CFU/seed. Preferably, the concentration is about 1×106 to about 1×109 CFU/seed. In the case of the microbial pesticides II, the application rates with respect to plant propagation material also preferably range from about 1×107 to 1×1014 (or more) CFU per 100 kg of seed, preferably from 1×109 to about 1×1012 CFU per 100 kg of seed.

The invention also relates to agrochemical compositions comprising an auxiliary and at least one compound of the present invention or a mixture thereof.

An agrochemical composition comprises a pesticidally effective amount of a compound of the present invention or a mixture thereof. The term “pesticidally effective amount” is defined below.

The compounds of the present invention or the mixtures thereof can be converted into customary types of agro-chemical compositions, e. g. solutions, emulsions, suspensions, dusts, powders, pastes, granules, pressings, capsules, and mixtures thereof. Examples for composition types are suspensions (e.g. SC, OD, FS), emulsifiable concentrates (e.g. EC), emulsions (e.g. EW, EO, ES, ME), capsules (e.g. CS, ZC), pastes, pastilles, wettable powders or dusts (e.g. WP, SP, WS, DP, DS), pressings (e.g. BR, TB, DT), granules (e.g. WG, SG, GR, FG, GG, MG), insecticidal articles (e.g. LN), as well as gel formulations for the treatment of plant propagation materials such as seeds (e.g. GF). These and further compositions types are defined in the “Catalogue of pesticide formulation types and international coding system”, Technical Mono-graph No. 2, 6th Ed. May 2008, CropLife International.

The compositions are prepared in a known manner, such as described by Mollet and Grube-mann, Formulation technology, Wiley VCH, Weinheim, 2001; or Knowles, New developments in crop protection product formulation, Agrow Reports DS243, T&F Informa, London, 2005.

Examples for suitable auxiliaries are solvents, liquid carriers, solid carriers or fillers, surfactants, dispersants, emulsifiers, wetters, adjuvants, solubilizers, penetration enhancers, protec-tive colloids, adhesion agents, thickeners, humectants, repellents, attractants, feeding stimu-lants, compatibilizers, bactericides, anti-freezing agents, anti-foaming agents, colorants, tackifi-ers and binders.

Suitable solvents and liquid carriers are water and organic solvents, such as mineral oil frac-tions of medium to high boiling point, e.g. kerosene, diesel oil; oils of vegetable or animal origin; aliphatic, cyclic and aromatic hydrocarbons, e. g. toluene, paraffin, tetrahydronaphthalene, al-kylated naphthalenes; alcohols, e.g. ethanol, propanol, butanol, benzylalcohol, cyclo¬hexanol; glycols; DMSO; ketones, e.g. cyclohexanone; esters, e.g. lactates, carbonates, fatty acid esters, gamma-butyrolactone; fatty acids; phosphonates; amines; amides, e.g. N-methylpyrrolidone, fatty acid dimethylamides; and mixtures thereof.

Suitable solid carriers or fillers are mineral earths, e.g. silicates, silica gels, talc, kaolins, limestone, lime, chalk, clays, dolomite, diatomaceous earth, bentonite, calcium sulfate, magnesium sulfate, magnesium oxide; polysaccharide powders, e.g. cellulose, starch; fertilizers, e.g. ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas; products of vegetable origin, e.g. cereal meal, tree bark meal, wood meal, nutshell meal, and mixtures thereof.

Suitable surfactants are surface-active compounds, such as anionic, cationic, nonionic and amphoteric surfactants, block polymers, polyelectrolytes, and mixtures thereof. Such surfactants can be used as emusifier, dispersant, solubilizer, wetter, penetration enhancer, protective colloid, or adjuvant. Examples of surfactants are listed in McCutcheon's, Vol. 1: Emulsifiers & Detergents, McCutcheon's Directories, Glen Rock, USA, 2008 (International Ed. or North American Ed.).

Suitable anionic surfactants are alkali, alkaline earth or ammonium salts of sulfonates, sulfates, phosphates, carboxylates, and mixtures thereof. Examples of sulfonates are alkylaryl-sulfonates, diphenylsulfonates, alpha-olefin sulfonates, lignine sulfonates, sulfonates of fatty acids and oils, sulfonates of ethoxylated alkylphenols, sulfonates of alkoxylated arylphenols, sulfonates of condensed naphthalenes, sulfonates of dodecyl- and tridecylbenzenes, sulfonates of naphthalenes and alkyhnaphthalenes, sulfosuccinates or sulfosuccinamates. Examples of sulfates are sulfates of fatty acids and oils, of ethoxylated alkylphenols, of alcohols, of ethox-ylated alcohols, or of fatty acid esters. Examples of phosphates are phosphate esters. Exam-pies of carboxylates are alkyl carboxylates, and carboxylated alcohol or alkylphenol eth-oxylates.

Suitable nonionic surfactants are alkoxylates, N-substituted fatty acid amides, amine oxides, esters, sugar-based surfactants, polymeric surfactants, and mixtures thereof. Examples of alkoxylates are compounds such as alcohols, alkylphenols, amines, amides, arylphenols, fatty acids or fatty acid esters which have been alkoxylated with 1 to 50 equivalents. Ethylene oxide and/or propylene oxide may be employed for the alkoxylation, preferably ethylene oxide. Exam-pies of N-substituted fatty acid amides are fatty acid glucamides or fatty acid alkanolamides. Examples of esters are fatty acid esters, glycerol esters or monoglycerides. Examples of sugar-based surfactants are sorbitans, ethoxylated sorbitans, sucrose and glucose esters or alkylpolyglucosides. Examples of polymeric surfactants are homo- or copolymers of vinylpyrrolidone, vinylalcohols, or vinylacetate.

Suitable cationic surfactants are quaternary surfactants, for example quaternary ammonium compounds with one or two hydrophobic groups, or salts of long-chain primary amines. Suitable amphoteric surfactants are alkylbetains and imidazolines. Suitable block polymers are block polymers of the A-B or A-B-A type comprising blocks of polyethylene oxide and polypropylene oxide, or of the A-B-C type comprising alkanol, polyethylene oxide and polypropylene oxide. Suitable polyelectrolytes are polyacids or polybases. Examples of polyacids are alkali salts of polyacrylic acid or polyacid comb polymers. Examples of polybases are polyvinylamines or polyethyleneamines.

Suitable adjuvants are compounds, which have a neglectable or even no pesticidal activity themselves, and which improve the biological performance of the compounds of the present invention on the target. Examples are surfactants, mineral or vegetable oils, and other auxilaries. Further examples are listed by Knowles, Adjuvants and additives, Agrow Reports DS256, T&F Informa UK, 2006, chapter 5.

Suitable thickeners are polysaccharides (e.g. xanthan gum, carboxymethylcellulose), anorganic clays (organically modified or unmodified), polycarboxylates, and silicates.

Suitable bactericides are bronopol and isothiazolinone derivatives such as alkylisothiazolinones and benzisothiazolinones.

Suitable anti-freezing agents are ethylene glycol, propylene glycol, urea and glycerin.

Suitable anti-foaming agents are silicones, long chain alcohols, and salts of fatty acids.

Suitable colorants (e.g. in red, blue, or green) are pigments of low water solubility and water-soluble dyes. Examples are inorganic colorants (e.g. iron oxide, titan oxide, iron hexacyanofer-rate) and organic colorants (e.g. alizarin-, azo- and phthalocyanine colorants).

Suitable tackifiers or binders are polyvinylpyrrolidons, polyvinylacetates, polyvinyl alcohols, polyacrylates, biological or synthetic waxes, and cellulose ethers.

Examples for composition types and their preparation are:

i) Water-soluble concentrates (SL, LS)

10-60 wt % of a compound I according to the invention and 5-15 wt % wetting agent (e.g. alcohol alkoxylates) are dissolved in water and/or in a water-soluble solvent (e.g. alcohols) up to 100 wt %. The active substance dissolves upon dilution with water.

ii) Dispersible concentrates (DC)

5-25 wt % of a compound I according to the invention and 1-10 wt % dispersant (e. g. polyvinylpyrrolidone) are dissolved in up to 100 wt % organic solvent (e.g. cyclohexanone). Dilution with water gives a dispersion.

iii) Emulsifiable concentrates (EC)

15-70 wt % of a compound I according to the invention and 5-10 wt % emulsifiers (e.g. calcium dodecylbenzenesulfonate and castor oil ethoxylate) are dissolved in up to 100 wt % water-insoluble organic solvent (e.g. aromatic hydrocarbon). Dilution with water gives an emulsion.

iv) Emulsions (EW, EO, ES)

5-40 wt % of a compound I according to the invention and 1-10 wt % emulsifiers (e.g. calcium dodecylbenzenesulfonate and castor oil ethoxylate) are dissolved in 20-40 wt % water-insoluble organic solvent (e.g. aromatic hydrocarbon). This mixture is introduced into up to 100 wt % water by means of an emulsifying machine and made into a homogeneous emulsion. Dilution with water gives an emulsion.

v) Suspensions (SC, OD, FS)

In an agitated ball mill, 20-60 wt % of a compound I according to the invention are comminuted with addition of 2-10 wt % dispersants and wetting agents (e.g. sodium lignosulfonate and alcohol ethoxylate), 0.1-2 wt % thickener (e.g. xanthan gum) and up to 100 wt % water to give a fine active substance suspension. Dilution with water gives a stable suspension of the active sub-stance. For FS type composition up to 40 wt % binder (e.g. polyvinylalcohol) is added.

vi) Water-dispersible granules and water-soluble granules (WG, SG)

50-80 wt % of a compound I according to the invention are ground finely with addition of up to 100 wt % dispersants and wetting agents (e.g. sodium lignosulfonate and alcohol ethoxylate) and prepared as water-dispersible or water-soluble granules by means of technical appliances (e. g. extrusion, spray tower, fluidized bed). Dilution with water gives a stable dispersion or solution of the active substance.

vii) Water-dispersible powders and water-soluble powders (WP, SP, WS)

50-80 wt % of a compound I according to the invention are ground in a rotor-stator mill with ad-dition of 1-5 wt % dispersants (e.g. sodium lignosulfonate), 1-3 wt % wetting agents (e.g. alcohol ethoxylate) and up to 100 wt % solid carrier, e.g. silica gel. Dilution with water gives a stable dis-persion or solution of the active substance.

viii) Gel (GW, GF)

In an agitated ball mill, 5-25 wt % of a compound I according to the invention are comminuted with addition of 3-10 wt % dispersants (e.g. sodium lignosulfonate), 1-5 wt % thickener (e.g. car-boxymethylcellulose) and up to 100 wt % water to give a fine suspension of the active sub-stance. Dilution with water gives a stable suspension of the active substance.

ix) Microemulsion (ME)

5-20 wt % of a compound I according to the invention are added to 5-30 wt % organic solvent blend (e.g. fatty acid dimethylamide and cyclohexanone), 10-25 wt % surfactant blend (e.g. alkohol ethoxylate and arylphenol ethoxylate), and water up to 100%. This mixture is stirred for 1 h to produce spontaneously a thermodynamically stable microemulsion.

x) Microcapsules (CS)

An oil phase comprising 5-50 wt % of a compound I according to the invention, 0-40 wt % water insoluble organic solvent (e.g. aromatic hydrocarbon), 2-15 wt % acrylic monomers (e.g. methylmethacrylate, methacrylic acid and a di- or triacrylate) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl alcohol). Radical polymerization initiated by a radi-cal initiator results in the formation of poly(meth)acrylate microcapsules. Alternatively, an oil phase comprising 5-50 wt % of a compound I according to the invention, 0-40 wt % water insolu-ble organic solvent (e.g. aromatic hydrocarbon), and an isocyanate monomer (e.g. diphenylme-thene-4,4′-diisocyanatae) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl alcohol). The addition of a polyamine (e.g. hexamethylenediamine) results in the for-mation of a polyurea microcapsule. The monomers amount to 1-10 wt %. The wt % relate to the total CS composition.

xi) Dustable powders (DP, DS)

1-10 wt % of a compound I according to the invention are ground finely and mixed intimately with up to 100 wt % solid carrier, e.g. finely divided kaolin.

xii) Granules (GR, FG)

0.5-30 wt % of a compound I according to the invention is ground finely and associated with up to 100 wt % solid carrier (e.g. silicate). Granulation is achieved by extrusion, spray-drying or the fluidized bed.

xiii) Ultra-low volume liquids (UL)

1-50 wt % of a compound I according to the invention are dissolved in up to 100 wt % organic solvent, e.g. aromatic hydrocarbon.

The compositions types i) to xi) may optionally comprise further auxiliaries, such as 0.1-1 wt % bactericides, 5-15 wt % anti-freezing agents, 0.1-1 wt % anti-foaming agents, and 0.1-1 wt % colorants.

The agrochemical compositions generally comprise between 0.01 and 95%, preferably between 0.1 and 90%, and most preferably between 0.5 and 75%, by weight of active sub-stance. The active substances are employed in a purity of from 90% to 100%, preferably from 95% to 100% (according to NMR spectrum).

Various types of oils, wetters, adjuvants, fertilizer, or micronutrients, and other pesticides (e.g. herbicides, insecticides, fungicides, growth regulators, safeners) may be added to the active substances or the compositions comprising them as premix or, if appropriate not until immediately prior to use (tank mix). These agents can be admixed with the compositions according to the invention in a weight ratio of 1:100 to 100:1, preferably 1:10 to 10:1.

The user applies the composition according to the invention usually from a predosage de-vice, a knapsack sprayer, a spray tank, a spray plane, or an irrigation system. Usually, the agrochemical composition is made up with water, buffer, and/or further auxiliaries to the desired application concentration and the ready-to-use spray liquor or the agrochemical composition according to the invention is thus obtained. Usually, 20 to 2000 liters, preferably 50 to 400 liters, of the ready-to-use spray liquor are applied per hectare of agricultural useful area.

According to one embodiment, individual components of the composition according to the in-vention such as parts of a kit or parts of a binary or ternary mixture may be mixed by the user himself in a spray tank and further auxiliaries may be added, if appropriate.

In a further embodiment, either individual components of the composition according to the invention or partially premixed components, e. g. components comprising compounds of the present invention and/or mixing partners as defined above, may be mixed by the user in a spray tank and further auxiliaries and additives may be added, if appropriate.

In a further embodiment, either individual components of the composition according to the in-vention or partially premixed components, e. g. components comprising compounds of the present invention and/or mixing partners as defined above, can be applied jointly (e.g. after tank mix) or consecutively.

The compounds of the present invention are suitable for use in protecting crops, plants, plant propagation materials, such as seeds, or soil or water, in which the plants are growing, from attack or infestation by animal pests. Therefore, the present invention also relates to a plant protection method, which comprises contacting crops, plants, plant propagation materials, such as seeds, or soil or water, in which the plants are growing, to be protected from attack or infestation by animal pests, with a pesticidally effective amount of a compound of the present invention.

The compounds of the present invention are also suitable for use in combating or controlling animal pests. Therefore, the present invention also relates to a method of combating or controlling animal pests, which comprises contacting the animal pests, their habitat, breeding ground, or food supply, or the crops, plants, plant propagation materials, such as seeds, or soil, or the area, material or environment in which the animal pests are growing or may grow, with a pesticidally effective amount of a compound of the present invention.

The compounds of the present invention are effective through both contact and ingestion. Furthermore, the compounds of the present invention can be applied to any and all developmental stages, such as egg, larva, pupa, and adult.

The compounds of the present invention can be applied as such or in form of compositions comprising them as defined above. Furthermore, the compounds of the present invention can be applied together with a mixing partner as defined above or in form of compositions comprising said mixtures as defined above. The components of said mixture can be applied simultaneously, jointly or separately, or in succession, that is immediately one after another and thereby creating the mixture “in situ” on the desired location, e.g. the plant, the sequence, in the case of separate application, generally not having any effect on the result of the control measures.

The application can be carried out both before and after the infestation of the crops, plants, plant propagation materials, such as seeds, soil, or the area, material or environment by the pests.

Suitable application methods include inter alia soil treatment, seed treatment, in furrow application, and foliar application. Soil treatment methods include drenching the soil, drip irrigation (drip application onto the soil), dipping roots, tubers or bulbs, or soil injection. Seed treatment techniques include seed dressing, seed coating, seed dusting, seed soaking, and seed pelleting. In furrow applications typically include the steps of making a furrow in cultivated land, seeding the furrow with seeds, applying the pesticidally active compound to the furrow, and closing the furrow. Foliar application refers to the application of the pesticidally active compound to plant foliage, e.g. through spray equipment. For foliar applications, it can be advantageous to modify the behavior of the pests by use of pheromones in combination with the compounds of the present invention. Suitable pheromones for specific crops and pests are known to a skilled person and publicly available from databases of pheromones and semiochemicals, such as http://www.pherobase.com.

As used herein, the term “contacting” includes both direct contact (applying the compounds/compositions directly on the animal pest or plant—typically to the foliage, stem or roots of the plant) and indirect contact (applying the compounds/compositions to the locus, i.e. habitat, breeding ground, plant, seed, soil, area, material or environment in which a pest is growing or may grow, of the animal pest or plant).

The term “animal pest” includes arthropods, gastropods, and nematodes. Preferred animal pests according to the invention are arthropods, preferably insects and arachnids, in particular insects. Insects, which are of particular relevance for crops, are typically referred to as crop insect pests.

The term “crop” refers to both, growing and harvested crops.

The term “plant” includes cereals, e.g. durum and other wheat, rye, barley, triticale, oats, rice, or maize (fodder maize and sugar maize/sweet and field corn); beet, e.g. sugar beet or fodder beet; fruits, such as pomes, stone fruits or soft fruits, e.g. apples, pears, plums, peaches, nectarines, almonds, cherries, papayas, strawberries, raspberries, blackberries or gooseberries; leguminous plants, such as beans, lentils, peas, alfalfa or soybeans; oil plants, such as rapeseed (oilseed rape), turnip rape, mustard, olives, sunflowers, coconut, cocoa beans, castor oil plants, oil palms, ground nuts or soybeans; cucurbits, such as squashes, pumpkins, cucumber or melons; fiber plants, such as cotton, flax, hemp or jute; citrus fruit, such as oranges, lemons, grapefruits or mandarins; vegetables, such as eggplant, spinach, lettuce (e.g. iceberg lettuce), chicory, cabbage, asparagus, cabbages, carrots, onions, garlic, leeks, tomatoes, potatoes, cucurbits or sweet peppers; lauraceous plants, such as avocados, cinnamon or camphor; energy and raw material plants, such as corn, soybean, rapeseed, sugar cane or oil palm; tobacco; nuts, e.g. walnuts; pistachios; coffee; tea; bananas; vines (table grapes and grape juice grape vines); hop; sweet leaf (also called Stevia); natural rubber plants or ornamental and forestry plants, such as flowers (e.g. carnation, petunias, geranium/pelargoniums, pansies and impatiens), shrubs, broad-leaved trees (e.g. poplar) or evergreens, e.g. conifers; eucalyptus; turf; lawn; grass such as grass for animal feed or ornamental uses. Preferred plants include potatoes sugar beets, tobacco, wheat, rye, barley, oats, rice, corn, cotton, soybeans, rapeseed, legumes, sunflowers, coffee or sugar cane; fruits; vines; ornamentals; or vegetables, such as cucumbers, tomatoes, beans or squashes.

The term “plant” is to be understood as including wild type plants and plants, which have been modified by either conventional breeding, or mutagenesis or genetic engineering, or by a combination thereof.

Plants, which have been modified by mutagenesis or genetic engineering, and are of particular commercial importance, include alfalfa, rapeseed (e.g. oilseed rape), bean, carnation, chicory, cotton, eggplant, eucalyptus, flax, lentil, maize, melon, papaya, petunia, plum, poplar, potato, rice, soybean, squash, sugar beet, sugarcane, sunflower, sweet pepper, tobacco, tomato, and cereals (e.g. wheat), in particular maize, soybean, cotton, wheat, and rice. In plants, which have been modified by mutagenesis or genetic engineering, one or more genes have been mutagenized or integrated into the genetic material of the plant. The one or more mutagenized or integrated genes are preferably selected from pat, epsps, cry1Ab, bar, cry1Fa2, cry1Ac, cry34Ab1, cry35AB1, cry3A, cryF, cry1F, mcry3a, cry2Ab2, cry3Bb1, cry1A.105, dfr, barnase, vip3Aa20, barstar, als, bxn, bp40, asn1, and ppo5. The mutagenesis or integration of the one or more genes is performed in order to improve certain properties of the plant. Such properties, also known as traits, include abiotic stress tolerance, altered growth/yield, disease resistance, herbicide tolerance, insect resistance, modified product quality, and pollination control. Of these properties, herbicide tolerance, e.g. imidazolinone tolerance, glyphosate tolerance, or glufosinate tolerance, is of particular importance. Several plants have been rendered tolerant to herbicides by mutagenesis, for example Clearfield® oilseed rape being tolerant to imidazolinones, e.g. imazamox. Alternatively, genetic engineering methods have been used to render plants, such as soybean, cotton, corn, beets and oil seed rape, tolerant to herbicides, such as glyphosate and glufosinate, some of which are commercially available under the trade names RoundupReady® (glyphosate) and LibertyLink® (glufosinate). Furthermore, insect resistance is of importance, in particular lepidopteran insect resistance and coleopteran insect resistance. Insect resistance is typically achieved by modifying plants by integrating cry and/or vip genes, which were isolated from Bacillus thuringiensis (Bt), and code for the respective Bt toxins. Genetically modified plants with insect resistance are commercially available under trade names including WideStrike®, Bollgard®, Agrisure®, Herculex®, YieldGard®, Genuity®, and Intacta®. Plants may be modified by mutagenesis or genetic engineering either in terms of one property (singular traits) or in terms of a combination of properties (stacked traits). Stacked traits, e.g. the combination of herbicide tolerance and insect resistance, are of increasing importance. In general, all relevant modified plants in connection with singular or stacked traits as well as detailed information as to the mutagenized or integrated genes and the respective events are available from websites of the organizations “International Service for the Acquisition of Agri-biotech Applications (ISAAA)” (http://www.isaaa.org/gmapprovaldatabase) and “Center for Environmental Risk Assessment (CERA)” (http://cera-qmc.org/GMCropDatabase).

It has surprisingly been found that the pesticidal activity of the compounds of the present invention may be enhanced by the insecticidal trait of a modified plant. Furthermore, it has been found that the compounds of the present invention are suitable for preventing insects to become resistant to the insecticidal trait or for combating pests, which already have become resistant to the insecticidal trait of a modified plant. Moreover, the compounds of the present invention are suitable for combating pests, against which the insecticidal trait is not effective, so that a complementary insecticidal activity can advantageously be used.

The term “plant propagation material” refers to all the generative parts of the plant such as seeds and vegetative plant material such as cuttings and tubers (e.g. potatoes), which can be used for the multiplication of the plant. This includes seeds, roots, fruits, tubers, bulbs, rhizomes, shoots, sprouts and other parts of plants. Seedlings and young plants, which are to be transplanted after germination or after emergence from soil, may also be included. These plant propagation materials may be treated prophylactically with a plant protection compound either at or before planting or transplanting.

The term “seed” embraces seeds and plant propagules of all kinds including but not limited to true seeds, seed pieces, suckers, corms, bulbs, fruit, tubers, grains, cuttings, cut shoots and the like, and means in a preferred embodiment true seeds.

In general, “pesticidally effective amount” means the amount of active ingredient needed to achieve an observable effect on growth, including the effects of necrosis, death, retardation, prevention, and removal, destruction, or otherwise diminishing the occurrence and activity of the target organism. The pesticidally effective amount can vary for the various compounds/compositions used in the invention. A pesticidally effective amount of the compositions will also vary according to the prevailing conditions such as desired pesticidal effect and duration, weather, target species, locus, mode of application, and the like.

In the case of soil treatment, in furrow application or of application to the pests dwelling place or nest, the quantity of active ingredient ranges from 0.0001 to 500 g per 100 m², preferably from 0.001 to 20 g per 100 m².

For use in treating crop plants, e.g. by foliar application, the rate of application of the active ingredients of this invention may be in the range of 0.0001 g to 4000 g per hectare, e.g. from 1 g to 2 kg per hectare or from 1 g to 750 g per hectare, desirably from 1 g to 100 g per hectare, more desirably from 10 g to 50 g per hectare, e.g., 10 to 20 g per hectare, 20 to 30 g per hectare, 30 to 40 g per hectare, or 40 to 50 g per hectare.

The compounds of the present invention are particularly suitable for use in the treatment of seeds in order to protect the seeds from insect pests, in particular from soil-living insect pests, and the resulting seedling's roots and shoots against soil pests and foliar insects. The present invention therefore also relates to a method for the protection of seeds from insects, in particular from soil insects, and of the seedling's roots and shoots from insects, in particular from soil and foliar insects, said method comprising treating the seeds before sowing and/or after pregermination with a compound of the present invention. The protection of the seedling's roots and shoots is preferred. More preferred is the protection of seedling's shoots from piercing and sucking insects, chewing insects and nematodes.

The term “seed treatment” comprises all suitable seed treatment techniques known in the art, such as seed dressing, seed coating, seed dusting, seed soaking, seed pelleting, and in-furrow application methods. Preferably, the seed treatment application of the active compound is carried out by spraying or by dusting the seeds before sowing of the plants and before emergence of the plants.

The present invention also comprises seeds coated with or containing the active compound. The term “coated with and/or containing” generally signifies that the active ingredient is for the most part on the surface of the propagation product at the time of application, although a greater or lesser part of the ingredient may penetrate into the propagation product, depending on the method of application. When the said propagation product is (re)planted, it may absorb the active ingredient.

Suitable seed is for example seed of cereals, root crops, oil crops, vegetables, spices, ornamentals, for example seed of durum and other wheat, barley, oats, rye, maize (fodder maize and sugar maize/sweet and field corn), soybeans, oil crops, crucifers, cotton, sunflowers, bananas, rice, oilseed rape, turnip rape, sugarbeet, fodder beet, eggplants, potatoes, grass, lawn, turf, fodder grass, tomatoes, leeks, pumpkin/squash, cabbage, iceberg lettuce, pepper, cucumbers, melons, Brassica species, melons, beans, peas, garlic, onions, carrots, tuberous plants such as potatoes, sugar cane, tobacco, grapes, petunias, geranium/pelargoniums, pansies and impatiens.

In addition, the active compound may also be used for the treatment of seeds from plants, which have been modified by mutagenisis or genetic engineering, and which e.g. tolerate the action of herbicides or fungicides or insecticides. Such modified plants have been described in detail above.

Conventional seed treatment formulations include for example flowable concentrates FS, solutions LS, suspoemulsions (SE), powders for dry treatment DS, water dispersible powders for slurry treatment WS, water-soluble powders SS and emulsion ES and EC and gel formulation GF. These formulations can be applied to the seed diluted or undiluted. Application to the seeds is carried out before sowing, either directly on the seeds or after having pregerminated the latter. Preferably, the formulations are applied such that germination is not included.

The active substance concentrations in ready-to-use formulations, which may be obtained after two-to-tenfold dilution, are preferably from 0.01 to 60% by weight, more preferably from 0.1 to 40% by weight.

In a preferred embodiment a FS formulation is used for seed treatment. Typically, a FS formulation may comprise 1-800 g/l of active ingredient, 1-200 g/l Surfactant, 0 to 200 g/l antifreezing agent, 0 to 400 g/l of binder, 0 to 200 g/l of a pigment and up to 1 liter of a solvent, preferably water.

Especially preferred FS formulations of the compounds of the present invention for seed treatment usually comprise from 0.1 to 80% by weight (1 to 800 g/l) of the active ingredient, from 0.1 to 20% by weight (1 to 200 g/l) of at least one surfactant, e.g. 0.05 to 5% by weight of a wetter and from 0.5 to 15% by weight of a dispersing agent, up to 20% by weight, e.g. from 5 to 20% of an anti-freeze agent, from 0 to 15% by weight, e.g. 1 to 15% by weight of a pigment and/or a dye, from 0 to 40% by weight, e.g. 1 to 40% by weight of a binder (sticker/adhesion agent), optionally up to 5% by weight, e.g. from 0.1 to 5% by weight of a thickener, optionally from 0.1 to 2% of an anti-foam agent, and optionally a preservative such as a biocide, antioxidant or the like, e.g. in an amount from 0.01 to 1% by weight and a filler/vehicle up to 100% by weight.

In the treatment of seed, the application rates of the compounds of the invention are generally from 0.1 g to 10 kg per 100 kg of seed, preferably from 1 g to 5 kg per 100 kg of seed, more preferably from 1 g to 1000 g per 100 kg of seed and in particular from 1 g to 200 g per 100 kg of seed, e.g. from 1 g to 100 g or from 5 g to 100 g per 100 kg of seed.

The invention therefore also relates to seed comprising a compound of the present invention, or an agriculturally useful salt thereof, as defined herein. The amount of the compound of the present invention or the agriculturally useful salt thereof will in general vary from 0.1 g to 10 kg per 100 kg of seed, preferably from 1 g to 5 kg per 100 kg of seed, in particular from 1 g to 1000 g per 100 kg of seed. For specific crops such as lettuce the rate can be higher.

The invention also relates to composition comprising seed and a compound of the present invention, or an agriculturally useful salt thereof, as defined herein. The amount of the compound of the present invention or the agriculturally useful salt thereof will in general vary from 0.1 g to 10 kg per 100 kg of seed, preferably from 1 g to 5 kg per 100 kg of seed, in particular from 1 g to 1000 g per 100 kg of seed. For specific crops such as lettuce the rate can be higher.

The compounds of the present invention may also be used for improving the health of a plant. Therefore, the present invention also relates to a method for improving plant health by treating a plant, plant propagation material and/or the locus where the plant is growing or is to grow with an effective and non-phytotoxic amount of a compound of the present invention.

As used herein “an effective and non-phytotoxic amount” means that the compound is used in a quantity which allows to obtain the desired effect but which does not give rise to any phytotoxic symptom on the treated plant or on the plant grown from the treated propagule or treated soil.

The terms “plant” and “plant propagation material” are defined above.

“Plant health” is defined as a condition of the plant and/or its products which is determined by several aspects alone or in combination with each other such as yield (for example increased biomass and/or increased content of valuable ingredients), quality (for example improved content or composition of certain ingredients or shelf life), plant vigour (for example improved plant growth and/or greener leaves (“greening effect”), tolerance to abiotic (for example drought) and/or biotic stress (for example disease) and production efficiency (for example, harvesting efficiency, processability).

The above identified indicators for the health condition of a plant may be interdependent and may result from each other. Each indicator is defined in the art and can be determined by methods known to a skilled person.

The compounds of the invention are also suitable for use against non-crop insect pests. For use against said non-crop pests, compounds of the present invention can be used as bait composition, gel, general insect spray, aerosol, as ultra-low volume application and bed net (impregnated or surface applied). Furthermore, drenching and rodding methods can be used.

As used herein, the term “non-crop insect pest” refers to pests, which are particularly relevant for non-crop targets, such as ants, termites, wasps, flies, ticks, mosquitos, crickets, or cockroaches.

The bait can be a liquid, a solid or a semisolid preparation (e.g. a gel). The bait employed in the composition is a product, which is sufficiently attractive to incite insects such as ants, termites, wasps, flies, mosquitos, crickets etc. or cockroaches to eat it. The attractiveness can be manipulated by using feeding stimulants or sex pheromones. Food stimulants are chosen, for example, but not exclusively, from animal and/or plant proteins (meat-, fish- or blood meal, insect parts, egg yolk), from fats and oils of animal and/or plant origin, or mono-, oligo- or polyorganosaccharides, especially from sucrose, lactose, fructose, dextrose, glucose, starch, pectin or even molasses or honey. Fresh or decaying parts of fruits, crops, plants, animals, insects or specific parts thereof can also serve as a feeding stimulant. Sex pheromones are known to be more insect specific. Specific pheromones are described in the literature (e.g. http://www.pherobase.com), and are known to those skilled in the art.

For use in bait compositions, the typical content of active ingredient is from 0.001 weight % to 15 weight %, desirably from 0.001 weight % to 5% weight % of active compound.

Formulations of the compounds of the present invention as aerosols (e.g in spray cans), oil sprays or pump sprays are highly suitable for the non-professional user for controlling pests such as flies, fleas, ticks, mosquitos or cockroaches. Aerosol recipes are preferably composed of the active compound, solvents, furthermore auxiliaries such as emulsifiers, perfume oils, if appropriate stabilizers, and, if required, propellants.

The oil spray formulations differ from the aerosol recipes in that no propellants are used.

For use in spray compositions, the content of active ingredient is from 0.001 to 80 weights %, preferably from 0.01 to 50 weight % and most preferably from 0.01 to 15 weight %.

The compounds of the present invention and its respective compositions can also be used in mosquito and fumigating coils, smoke cartridges, vaporizer plates or long-term vaporizers and also in moth papers, moth pads or other heat-independent vaporizer systems.

Methods to control infectious diseases transmitted by insects (e.g. malaria, dengue and yellow fever, lymphatic filariasis, and leishmaniasis) with compounds of the present invention and its respective compositions also comprise treating surfaces of huts and houses, air spraying and impregnation of curtains, tents, clothing items, bed nets, tsetse-fly trap or the like. Insecticidal compositions for application to fibers, fabric, knitgoods, nonwovens, netting material or foils and tarpaulins preferably comprise a mixture including the insecticide, optionally a repellent and at least one binder.

The compounds of the present invention and its compositions can be used for protecting wooden materials such as trees, board fences, sleepers, frames, artistic artifacts, etc. and buildings, but also construction materials, furniture, leathers, fibers, vinyl articles, electric wires and cables etc. from ants and/or termites, and for controlling ants and termites from doing harm to crops or human being (e.g. when the pests invade into houses and public facilities).

Customary application rates in the protection of materials are, for example, from 0.001 g to 2000 g or from 0.01 g to 1000 g of active compound per m² treated material, desirably from 0.1 g to 50 g per m².

Insecticidal compositions for use in the impregnation of materials typically contain from 0.001 to 95 weight %, preferably from 0.1 to 45 weight %, and more preferably from 1 to 25 weight % of at least one repellent and/or insecticide.

The compounds of the the present invention are especially suitable for efficiently combating animal pests such as arthropods, gastropods and nematodes including but not limited to:

insects from the order of Lepidoptera, for example Achroia grisella, Acleris spp. such as A. fimbriana, A. gloverana, A. variana; Acrolepiopsis assectella, Acronicta major, Adoxophyes spp. such as A. cyrtosema, A. orana; Aedia leucomelas, Agrotis spp. such as A. exclamationis, A. fucosa, A. ipsiion, A. orthogoma, A. segetum, A. subterranea; Alabama argillacea, Aleurodicus dispersus, Alsophila pometaria, Ampelophaga rubiginosa, Amyeiois transitella, Anacampsis sarcitella, Anagasta kuehniella, Anarsia lineatella, Anisota senatoria, Antheraea pernyi, Anticarsia (=Thermesia) spp. such as A. gemmatalis; Apamea spp., Aproaerema modicella, Archips spp. such as A. argyrospila, A. fuscocupreanus, A. rosana, A. xyloseanus; Argyresthia conjugella, Argyroploce spp., Argyrotaenia spp. such as A. velutinana; Athetis mindara, Austroasca viridigrisea, Autographa gamma, Autographa nigrisigna, Barathra brassicae, Bedellia spp., Bonagota salubricola, Borbo cinnara, Bucculatrix thurberiella, Bupalus piniarius, Busseola spp., Cacoecia spp. such as C. murinana, C. podana; Cactoblastis cactorum, Cadra cautella, Calingo braziliensis, Caloptilis theivora, Capua reticulana, Carposina spp. such as C. niponensis, C. sasakii; Cephus spp., Chaetocnema aridula, Cheimatobia brumata, Chilo spp. such as C. indicus, C. suppressalis, C. partellus; Choreutis pariana, Choristoneura spp. such as C. conflictana, C. fumiferana, C. longicellana, C. murinana, C. occidentalis, C. rosaceana; Chrysodeixis (=Pseudoplusia) spp. such as C. eriosoma, C. includens; Cirphis unipuncta, Clysia ambiguella, Cnaphalocerus spp., Cnaphalocrocis medinalis, Cnephasia spp., Cochylis hospes, Coleophora spp., Colias eurytheme, Conopomorpha spp., Conotrachelus spp., Copitarsia spp., Corcyra cephalonica, Crambus caliginosellus, Crambus teterrellus, Crocidosema (=Epinotia) aporema, Cydalima (=Diaphania) perspectalis, Cydia (=Carpocapsa) spp. such as C. pomonella, C. latiferreana; Dalaca noctuides, Datana integerrima, Dasychira pinicola, Dendrolimus spp. such as D. pini, D. spectabilis, D. sibiricus; Desmia funeralis, Diaphania spp. such as D. nitidalis, D. hyalinata; Diatraea grandiosella, Diatraea saccharalis, Diphthera festiva, Earias spp. such as E. insulana, E. vittella; Ecdytolopha aurantianu, Egira (=Xylomyges) curialis, Elasmopalpus lignosellus, Eldana saccharina, Endopiza viteana, Ennomos subsignaria, Eoreuma loftini, Ephestia spp. such as E. cautella, E. elutella, E. kuehniella; Epinotia aporema, Epiphyas postvittana, Erannis tiliaria, Erionota thrax, Etiella spp., Eulia spp., Eupoecilia ambiguella, Euproctis chrysorrhoea, Euxoa spp., Evetria bouliana, Faronta albilinea, Feltia spp. such as F. subterranean; Galleria mellonella, Gracillaria spp., Grapholita spp. such as G. funebrana, G. molesta, G. inopinata; Halysidota spp., Harrisina americana, Hedylepta spp., Helicoverpa spp. such as H. armigera (=Heliothis armigera), H. zea (=Heliothis zea); Heliothis spp. such as H. assulta, H. subflexa, H. virescens; Hellula spp. such as H. undalis, H. rogatalis; Helocoverpa gelotopoeon, Flemileuca oliviae, Herpetogramma licarsisalis, Hibernia defoliaria, Hofmannophila pseudospretella, Homoeosoma electellum, Homona magnanima, Hypena scabra, Hyphantria cunea, Hyponomeuta padella, Hyponomeuta malinellus, Kakivoria flavofasciata, Keiferia lycopersicella, Lambdina fiscellaria fiscellaria, Lambdina fiscellaria lugubrosa, Lamprosema indicata, Laspeyresia molesta, Leguminivora glycinivorella, Lerodea eufala, Leucinodes orbonalis, Leucoma salicis, Leucoptera spp. such as L. coffeella, L. scitella; Leuminivora lycinivorella, Lithocolletis blancardella, Lithophane antennata, Llatiia octo (=Amyna axis), Lobesia botrana, Lophocampa spp., Loxagrotis albicosta, Loxostege spp. such as L. sticticalis, L cereralis; Lymantria spp. such as L. dispar, L. monacha; Lyonetia clerkella, Lyonetia prunifoliella, Malacosoma spp. such as M. americanum, M. californicum, M. constrictum, M. neustria; Mamestra spp. such as M. brassicae, M. configurata; Mamstra brassicae, Manduca spp. such as M. quinquemaculata, M. sexta; Marasmia spp, Marmara spp., Maruca testulalis, Megalopyge lanata, Melanchra picta, Melanitis leda, Mods spp. such as M. lapites, M. repanda; Mods latipes, Monochroa fragariae, Mythimna separata, Nemapogon doacella, Neoleudnodes elegantalis, Nepytia spp., Nymphula spp., Oiketicus spp., Omiodes indicata, Omphisa anastomosalis, Operophtera brumata, Orgyia pseudotsugata, Oria spp., Orthaga thyrisalis, Ostrinia spp. such as O. nubilalis; Oulema oryzae, Paleacrita vernata, Panolis fiammea, Parnara spp., Papaipema nebris, Papilio cresphontes, Paramyelois transitella, Paranthrene regalis, Paysandisia archon, Pedinophora spp. such as P. gossypiella; Peridroma sauda, Perileucoptera spp., such as P. coffeella; Phalera bucephala, Phryganidia californica, Phthorimaea spp. such as P. operculella; Phyllocnistis dtrella, Phyllonoryder spp. such as P. blancardella, P. crataegella, P. issikii, P. ringoniella; Pieris spp. such as P. brassicae, P. rapae, P. napi; Pilocrocis tripunctata, Plathypena scabra, Platynota spp. such as P. flavedana, P. idaeusalis, P. stultana; Platyptilia carduidactyla, Plebejus argus, Plodia interpunctella, Plusia spp, Plutella maculipennis, Plutella xylostella, Pontia protodica, Prays spp., Prodenia spp., Proxenus lepigone, Pseudaletia spp. such as P. sequax, P. unipuncta; Pyrausta nubilalis, Rachiplusia nu, Richia albicosta, Rhizobius ventralis, Rhyacionia frustrana, Sabulodes aegrotata, Schizura concinna, Schoenobius spp., Schreckensteinia festaliella, Scirpophaga spp. such as S. incertulas, S. innotata; Scotia segetum, Sesamia spp. such as S. inferens, Seudyra subflava, Sitotroga cerealella, Sparganothis pilleriana, Spilonota lechriaspis, S. ocellana, Spodoptera (=Lamphygma) spp. such as S. cosmoides, S. eridania, S. exigua, S. frugiperda, S. latisfascia, S. littoralis, S. litura, S. omithogalli; Stigmella spp., Stomopteryx subsecivella, Strymon bazochii, Sylepta derogata, Synanthedon spp. such as S. exitiosa, Tecia solanivora, Telehin licus, Thaumatopoea pityocampa, Thaumatotibia (=Cryptophlebia) leucotreta, Thaumetopoea pityocampa, Theda spp., Theresimima ampelophaga, Thyrinteina spp, Tildenia inconspicuella, Tinea spp. such as T. doacella, T. pellionella; Tineola bisselliella, Tortrix spp. such as T. viridana; Trichophaga tapetzella, Trichoplusia spp. such as T. ni; Tuta (=Scrobipalpula) absoluta, Udea spp. such as U. rubigalis, U. rubigalis; Virachola spp., Yponomeuta padella, and Zeiraphera canadensis;

insects from the order of Coleoptera, for example Acalymma vitiatum, Acanthoscehdes obtectus, Adoretus spp., Agelastica alni, Agrilus spp. such as A. anxius, A. planipennis, A. sinuatus; Agriotes spp. such as A. fuscicollis, A. lineatus, A. obscurus; Alphitobius diaperinus, Amphimallus solstitialis, Anisandrus dispar, Anisoplia austriaca, Anobium punctatum, Anomala corpulenta, Anomala rufocuprea, Anoplophora spp. such as A. glabripennis; Anthonomus spp. such as A. eugenii, A. grandis, A. pomorum; Anthrenus spp., Aphthona euphoridae, Apion spp., Apogonia spp., Athous haemorrhoidalis, Atomaria spp. such as A. linearis; Atiagenus spp., Aulacophora femoralis, Blastophagus piniperda, Blitophaga undata, Bruchidius obtectus, Bruchus spp. such as B. lentis, B. pisorum, B. rufimanus; Byctiscus betulae, Callidiellum rufipenne, Callopistria floridensis, Callosobruchus chinensis, Cameraria ohridella, Cassida nebulosa, Cerotoma trifurcata, Cetonia aurata, Ceuthorhynchus spp. such as C. assimilis, C. napi; Chaetocnema tibialis, Cleonus mendicus, Conoderus spp. such as C. vespertinus; Conotrachelus nenuphar, Cosmopolites spp., Costelytra zealandica, Crioceris asparagi, Cryptolestes ferrugineus, Cryptorhynchus lapathi, Ctenicera spp. such as C. destructor; Curculio spp., Cylindrocopturus spp., Cyclocephala spp., Dactylispa balyi, Dectes texanus, Dermestes spp., Diabrotica spp. such as D. undecimpunctata, D. speciosa, D. longicornis, D. semipunctata, D. virgifera; Diaprepes abbreviates, Dichocrocis spp., Dicladispa armigera, Diloboderus abderus, Diocalandra frumenti (Diocalandra stigmaticollis), Enaphalodes rufulus, Epilachna spp. such as E. varivestis, E. vigintioctomaculata; Epitrix spp. such as E. hirtipennis, E. similaris; Eutheola humilis, Eutinobothrus brasiliensis, Faustinus cubae, Gibbium psylloides, Gnathocerus cornutus, Hellula undalis, Heteronychus arator, Hyiamorpha elegans, Hylobius abietis, Hylotrupes bajulus, Hypera spp. such as H. brunneipennis, H. postica; Hypomeces squamosus, Hypothenemus spp., Ips typographus, Lachnosterna consanguinea, Lasioderma serricorne, Latheticus oryzae, Lathridius spp., Lema spp. such as L. bilineata, L. melanopus; Leptinotarsa spp. such as L. decemlineata; Leptispa pygmaea, Limonius californicus, Lissorhoptrus oryzophilus, Lixus spp., Luperodes spp., Lyctus spp. such as L. bruneus; Liogenys fuscus, Macrodactylus spp. such as M. subspinosus; Maladera matrida, Megaplatypus mutates, Megascelis spp., Melanotus communis, Meligethes spp. such as M. aeneus; Melolontha spp. such as M. hippocastani, M. melolontha; Metamasius hemipterus, Microtheca spp., Migdolus spp. such as M. fryanus, Monochamus spp. such as M. alternatus; Naupactus xanthographus, Niptus hololeucus, Oberia brevis, Oemona hirta, Oryctes rhinoceros, Oryzaephilus surinamensis, Oryzaphagus oryzae, Otiorrhynchus sulcatus, Otiorrhynchus ovatus, Otiorrhynchus sulcatus, Oulema melanopus, Oulema oryzae, Oxycetonia jucunda, Phaedon spp. such as P. brassicae, P. cochleariae; Phoracantha recurva, Phyllobius pyri, Phyllopertha horticola, Phyllophaga spp. such as P. helleri; Phyllotreta spp. such as P. chrysocephala, P. nemorum, P. striolata, P. vittula; Phyllopertha horticola, Popillia japonica, Premnotrypes spp., Psacothea hilaris, Psylliodes chrysocephala, Prostephanus truncates, Psylliodes spp., Ptinus spp., Pulga saltona, Rhizopertha dominica, Rhynchophorus spp. such as R. billineatus, R. ferrugineus, R. paimarum, R. phoenicis, R. vulneratus; Saperda Candida, Scolytus schevyrewi, Scyphophorus acupunctatus, Sitona lineatus, Sitophilus spp. such as S. granaria, S. oryzae, S. zeamais; Sphenophorus spp. such as S. levis; Stegobium paniceum, Sternechus spp. such as S. subsignatus; Strophomorphus ctenotus, Symphyletes spp., Tanymecus spp., Tenebrio molitop Tenebrioides mauretanicus, Tribolium spp. such as T. castaneum; Trogoderma spp., Tychius spp., Xylotrechus spp. such as X. pyrrhoderus; and, Zabrus spp. such as Z. tenebrioides;

insects from the order of Diptera for example Aedes spp. such as A. aegypti, A. albopictus, A. vexans; Anastrepha ludens, Anopheles spp. such as A. albimanus, A. crucians, A. freeborni, A. gambiae, A. leucosphyrus, A. maculipennis, A. minimus, A. quadrimaculatus, A. sinensis; Bactrocera invadens, Bibio hortulanus, Calliphora erythrocephala, Calliphora vicina, Ceratitis capitata, Chrysomyia spp. such as C. bezziana, C. hominivorax, C. maceiiaria; Chrysops atlanticus, Chrysops discalis, Chrysops silacea, Cochliomyia spp. such as C. hominivorax; Contarinia spp. such as C. sorghicola; Cordylobia anthropophaga, Culex spp. such as C. nigripalpus, C. pipiens, C. quinquefasciatus, C. tarsalis, C. tritaeniorhynchus; Culicoides furens, Culiseta inornata, Culiseta melanura, Cuterebra spp., Dacus cucurbitae, Dacus oleae, Dasineura brassicae, Dasineura oxycoccana, Delia spp. such as D. antique, D. coarctata, D. platura, D. radicum; Dermatobia hominis, Drosophila spp. such as D. suzukii, Fannia spp. such as F. canicularis; Gastraphilus spp. such as G. intestinalis; Geomyza tipunctata, Glossina spp. such as G. fuscipes, G. morsitans, G. palpalis, G. tachinoides; Haematobia irritans, Haplodiplosis equestris, Hippelates spp., Hylemyia spp. such as H. platura; Hypoderma spp. such as H. lineata; Hyppobosca spp., Hydrellia philippina, Leptoconops torrens, Liriomyza spp. such as L. sativae, L trifolii; Lucilia spp. such as L. caprina, L. cuprina, L. sericata; Lycoria pectoralis, Mansonia titillanus, Mayetiola spp. such as M. destructor; Musca spp. such as M. autumnalis, M. domestica; Muscina stabulans, Oestrus spp. such as O. ovis; Opomyza florum, Oscinella spp. such as O. frit; Orseolia oryzae, Pegomya hysocyami, Phlebotomus argentipes, Phorbia spp. such as P. antiqua, P. brassicae, P. coarctata; Phytomyza gymnostoma, Prosimulium mixtum, Psila rosae, Psorophora columbiae, Psorophora discolor, Rhagoletis spp. such as R. cerasi, R. cingulate, R. indifferens, R. mendax, R. pomonella; Rivellia quadrifasciata, Sarcophaga spp. such as S. haemorrhoidalis; Simulium vittatum, Sitodiplosis moseiiana, Stomoxys spp. such as S. calcitrans; Tabanus spp. such as T. atratus, T. bovinus, T. lineola, T. similis; Tannia spp., Thecodiplosis japonensis, Tipula oleracea, Tipula paludosa, and Wohlfahrtia spp;

insects from the order of Thysanoptera for example, Baliothrips biformis, Dichromothrips corbetti, Dichromothrips ssp., Echinothrips americanus, Enneothrips flavens, Frankliniella spp. such as F. fusca, F. occidentalis, F. tritici; Heliothrips spp., Hercinothrips femoralis, Kakothrips spp., Microcephalothrips abdominalis, Neohydatothrips samayunkur, Pezothrips kellyanus, Rhipiphorothrips cruentatus, Sciriothrips spp. such as S. citri, S. dorsalis, S. perseae; Stenchaetothrips spp, Taeniothrips cardamoni, Taeniothrips inconsequens, Thrips spp. such as T. imagines, T. hawaiiensis, T. oryzae, T. palmi, T. parvispinus, T. tabaci;

insects from the order of Hemiptera for example, Acizzia jamatonica, Acrosternum spp. such as A. hilare; Acyrthosipon spp. such as A. onobrychis, A. pisum; Adelges laricis, Adelges tsugae, Adelphocoris spp., such as A. rapidus, A. superbus; Aeneolamia spp., Agonoscena spp., Aulacorthum solani, Aleurocanthus woglumi, Aleurodes spp., Aleurodicus disperses, Aleurolobus barodensis, Aleurothrixus spp., Amrasca spp., Anasa tristis, Antestiopsis spp., Anuraphis cardui, Aonidiella spp., Aphanostigma pin, Aphidula nasturtii, Aphis spp. such as A. cracdvora, A. fabae, A. forbesi, A. gossypii, A. grossulariae, A. maidiradids, A. pomi, A. sambud, A. schneideri, A. spiraecola; Arboridia apicalis, Arilus critatus, Aspidiella spp., Aspidiotus spp., Atanus spp., Aulacaspis yasumatsui, Aulacorthum solani, Bactericera cockerelli (Paratrioza cockerelli), Bemisia spp. such as B. argentifolii, B. tabaci (Aleurodes tabaci); Blissus spp. such as B. leucopterus; Brachycaudus spp. such as B. cardui, B. helichrysi, B. persicae, B. prunicola; Brachycolus spp., Brachycorynella asparagi, Brevicoryne brassicae, Cacopsylla spp. such as C. fulguralis, C. pyricola (Psylla pin); Calligypona marginata, Calocoris spp., Campylomma livida, Capitophorus horni, Carneocephala fulgida, Cavelerius spp., Ceraplastes spp., Ceratovacuna lanigera, Ceroplastes ceriferus, Cerosipha gossypii, Chaetosiphon fragaefolii, Chionaspis tegalensis, Chlorita onukii, Chromaphis juglandicola, Chrysomphalus ficus, Cicadulina mbila, Cimex spp. such as C. hemipterus, C. lectularius; Coccomytilus halli, Coccus spp. such as C. hesperidum, C. pseudomagnoliarum; Corythucha arcuata, Creontiades dilutus, Cryptomyzus ribis, Chrysomphalus aonidum, Cryptomyzus ribis, Ctenarytaina spatulata, Cyrtopeltis notatus, Dalbulus spp., Dasynus piperis, Dialeurodes spp. such as D. citrifolii; Dalbulus maidis, Diaphorina spp. such as D. citri; Diaspis spp. such as D. bromeliae; Dichelops furcatus, Diconocoris hewetti, Doralis spp., Dreyfusia nordmannianae, Dreyfusia piceae, Drosicha spp., Dysaphis spp. such as D. plantaginea, D. pyri, D. radicola; Dysaulacorthum pseudosolani, Dysdercus spp. such as D. cingulatus, D. intermedius; Dysmicoccus spp., Edessa spp., Geocoris spp., Empoasca spp. such as E. fabae, E. solana; Epidiaspis leperii, Eriosoma spp. such as E. lanigerum, E. pyricola; Erythroneura spp., Eurygaster spp. such as E. integriceps; Euscelis bilobatus, Euschistus spp. such as E. heros, E. impictiventris, E. servus; Fiorinia theae, Geococcus coffeae, Glycaspis brimblecombei, Halyomorpha spp. such as H. halys; Heliopeltis spp., Homalodisca vitripennis (=H. coagulata), Horcias nobilellus, Hyalopterus pruni, Hyperomyzus lactucae, Icerya spp. such as I. purchase; Idiocerus spp., Idioscopus spp., Laodelphax striatellus, Lecanium spp., Lecanoideus floccissimus, Lepidosaphes spp. such as L. ulmi; Leptocorisa spp., Leptoglossus phyllopus, Lipaphis erysimi, Lygus spp. such as L. hesperus, L lineolaris, L pratensis; Maconellicoccus hirsutus, Marchalina hellenica, Macropes excavatus, Macrosiphum spp. such as M. rosae, M. avenae, M. euphorbiae; Macrosteles quadrilineatus, Mahanarva fimbriolata, Megacopta cribraria, Megoura viciae, Melanaphis pyrarius, Melanaphis sacchari, Melanocallis (=Tinocallis) caryaefoliae, Metcafiella spp., Metopolophium dirhodum, Monellia costalis, Monelliopsis pecanis, Myzocallis coryli, Murgantia spp., Myzus spp. such as M. ascalonicus, M. cerasi, M. nicotianae, M. persicae, M. varians; Nasonovia ribis-nigri, Neotoxoptera formosana, Neomegalotomus spp, Nephotettix spp. such as N. malayanus, N. nigropictus, N. parvus, N. virescens; Nezara spp. such as N. viridula; Nilaparvata lugens, Nysius huttoni, Oebalus spp. such as O. pugnax; Oncometopia spp., Orthezia praeionga, Oxycaraenus hyalinipennis, Parabemisia myricae, Parlatoria spp., Parthenolecanium spp. such as P. corni, P. persicae; Pemphigus spp. such as P. bursarius, P. populivenae; Peregrinus maidis, Perkinsiella saccharicida, Phenacoccus spp. such as P. aceris, P. gossypii; Phloeomyzus passerinii, Phorodon humuli, Phylloxera spp. such as P. devastatrix, Piesma quadrata, Piezodorus spp. such as P. guildinii; Pirmaspis aspidistrae, Pianococcus spp. such as P. citri, P. ficus; Prosapia bicincta, Protopulvinaria pyriformis, Psallus seriatus, Pseudacysta persea, Pseudaulacaspis pentagona, Pseudococcus spp. such as P. comstocki; Psylla spp. such as P. mali; Pteromalus spp., Pulvinaria amygdali, Pyrilla spp., Quadraspidiotus spp., such as Q. perniciosus; Quesada gigas, Rastrococcus spp., Reduvius senilis, Rhizoecus americanus, Rhodnius spp., Rhopalomyzus ascalonicus, Rhopalosiphum spp. such as R. pseudobrassicas, R. insertum, R. maidis, R. padi; Sagatodes spp., Sahlbergella singularis, Saissetia spp., Sappaphis mala, Sappaphis mali, Scaptocoris spp., Scaphoides titanus, Schizaphis graminum, Schizoneura lanuginosa, Scotinophora spp., Selenaspidus articulatus, Sitobion avenae, Sogata spp., Sogatella furcifera, Solubea insularis, Spissistilus festinus (=Stictocephala festina), Stephanitis nashi, Stephanitis pyrioides, Stephanitis takeyai, Tenaiaphara malayensis, Tetraleurodes perseae, Therioaphis maculate, Thyanta spp. such as T. accerra, T. perditor; Tibraca spp., Tomaspis spp., Toxoptera spp. such as T. aurantii; Trialeurodes spp. such as T. abutilonea, T. ricini, T. vaporariorum; Triatoma spp., Trioza spp., Typhlocyba spp., Unaspis spp. such as U. citri, U. yanonensis; and Viteus vitifolii,

Insects from the order Hymenoptera for example Acanthomyops interjectus, Athalia rosae, Atta spp. such as A. capiguara, A. cephalotes, A. cephalotes, A. laevigata, A. robusta, A. sexdens, A. texana, Bombus spp., Brachymyrmex spp., Camponotus spp. such as C. floridanus, C. pennsylvanicus, C. modoc; Cardiocondyla nuda, Chalibion sp, Crematogaster spp., Dasymutilla occidentalis, Diprion spp., Dolichovespula maculata, Dorymyrmex spp., Dryocosmus kuriphilus, Formica spp., Hoplocampa spp. such as H. minuta, H. testudinea; Iridomyrmex humilis, Lasius spp. such as L. nigep Linepithema humile, Liometopum spp., Leptocybe invasa, Monomorium spp. such as M. pharaonis, Monomorium, Nylandria fulva, Pachycondyla chinensis, Paratrechina longicornis, Paravespula spp., such as P. germanica, P. pennsylvanica, P. vulgaris; Pheidole spp. such as P. megacephala; Pogonomyrmex spp. such as P. barbatus, P. californicus, Polistes rubiginosa, Prenolepis impairs, Pseudomyrmex gracilis, Schelipron spp., Sirex cyaneus, Solenopsis spp. such as S. geminata, Sjnvicta, S. molesta, S. richteri, S. xyloni, Sphecius speciosus, Sphex spp., Tapinoma spp. such as T. melanocephalum, T. sessile; Tetramorium spp. such as T. caespitum, T. bicarinatum, Vespa spp. such as V. crabro; Vespula spp. such as V. squamosal; Wasmarmia auropunctata, Xylocopa sp;

Insects from the order Orthoptera for example Acheta domesticus, Calliptamus italicus, Chortoicetes terminifera, Ceuthophilus spp., Diastrammena asynamora, Dociostaurus maroccanus, Gryllotalpa spp. such as G. africana, G. gryllotalpa; Gryllus spp., Hieroglyph us daganensis, Kraussaria angulifera, Locusta spp. such as L. migratoria, L. pardalina; Meianopius spp. such as M. bivittatus, M. femurrubrum, M. mexicanus, M. sanguinipes, M. spretus; Nomadacris septemfasciata, Oedaleus senegalensis, Scapteriscus spp., Schistocerca spp. such as S. amencana, S. gregaria, Stemopelmatus spp., Tachycines asynamorus, and Zonozerus variegatus;

Pests from the Class Arachnida for example Acari, e.g. of the families Argasidae, Ixodidae and Sarcoptidae, such as Amblyomma spp. (e.g. A. americanum, A. variegatum, A. maculatum), Argas spp. such as A. persicu), Boophilus spp. such as B. armulatus, B. decoloratus, B. microplus, Dermacentor spp. such as D. silvarum, D. andersoni, D. variabilis, Hyalomma spp. such as H. truncatum, Ixodes spp. such as I. ricinus, I. rubicundus, I. scapularis, I. holocyclus, I. pacificus, Rhipicephalus sanguineus, Ornithodorus spp. such as O. moubata, O. hermsi, O. turicata, Ornithonyssus bacoti, Otobius megnini, Dermanyssus gallinae, Psoroptes spp. such as P. ovis, Rhipicephalus spp. such as R. sanguineus, R. appendiculatus, Rhipicephalus evertsi, Rhizoglyphus spp., Sarcoptes spp. such as S. scabiei; and Family Eriophyidae including Aceria spp. such as A. sheldoni, A. anthocoptes, Acallitus spp., Aculops spp. such as A. lycopersici, A. pelekassk Aculus spp. such as A. schlechtendali; Colomerus vitis, Epitrimerus pyri, Phyllocoptruta oleivora; Eriophytes ribis and Eriophyes spp. such as Eriophyes sheldoni; Family Tarsonemidae including Hemitarsonemus spp., Phytonemus pallidus and Polyphagotarsonemus latus, Stenotarsonemus spp. Steneotarsonemus spinki; Family Tenuipalpidae including Brevipalpus spp. such as B. phoenicis; Family Tetranychidae including Eotetranychus spp., Eutetranychus spp., Oligonychus spp., Petrobia latens, Tetranychus spp. such as T. cinnabarinus, T. evansi, T. kanzawai, T, pacificus, T. phaseulus, T. telarius and T. urticae; Bryobia praetiosa; Panonychus spp. such as P. ulmi, P. citri; Metatetranychus spp. and Oligonychus spp. such as O. pratensis, O. perseae, Vasates lycopersici; Raoiella indica, Family Carpoglyphidae including Carpoglyphus spp.; Penthaleidae spp. such as Halotydeus destructor; Family Demodicidae with species such as Demodex spp.; Family Trombicidea including Trombicula spp.; Family Macronyssidae including Ornothonyssus spp.; Family Pyemotidae including Pyemotes tritici; Tyrophagus putrescentiae; Family Acaridae including Acarus siro; Family Araneida including Latrodectus mactans, Tegenaria agrestis, Chiracanthium sp, Lycosa sp Achaearanea tepidariorum and Loxosceles reclusa;

Pests from the Phylum Nematoda, for example, plant parasitic nematodes such as rootknot nematodes, Meloidogyne spp. such as M. hapla, M. incognita, M. javanica; cyst-forming nematodes, Globodera spp. such as G. rostochiensis; Heterodera spp. such as H. avenae, H. glycines, H. schachtii, H. trifolii; Seed gall nematodes, Anguina spp.; Stem and foliar nematodes, Aphelenchoides spp. such as A. besseyi; Sting nematodes, Belonolaimus spp. such as B. longicaudatus; Pine nematodes, Bursaphelenchus spp. such as B. lignicolus, B. xylophilus; Ring nematodes, Criconema spp., Criconemella spp. such as C. xenoplax and C. ornata; and, Criconemoides spp. such as Criconemoides informis; Mesocriconema spp.; Stem and bulb nematodes, Ditylenchus spp. such as D. destructor, D. dipsaci; Awl nematodes, Dolichodorus spp.; Spiral nematodes, Heliocotylenchus multicinctus; Sheath and sheathoid nematodes, Hemicycliophora spp. and Hemicriconemoides spp.; Hirshmanniella spp.; Lance nematodes, Hoploaimus spp.; False rootknot nematodes, Nacobbus spp.; Needle nematodes, Longidorus spp. such as L. elongatus; Lesion nematodes, Pratylenchus spp. such as P. brachyurus, P. neglectus, P. penetrans, P. curvitatus, P. goodeyi; Burrowing nematodes, Radopholus spp. such as R. similis; Rhadopholus spp.; Rhodopholus spp.; Reniform nematodes, Rotylenchus spp. such as R. robustus, R. reniformis; Scutellonema spp.; Stubby-root nematode, Trichodorus spp. such as T. obtusus, T. primitivus; Paratrichodorus spp. such as P. minor; Stunt nematodes, Tylenchorhynchus spp. such as T. claytoni, T. dubius; Citrus nematodes, Tylenchulus spp. such as T. semipenetrans; Dagger nematodes, Xiphinema spp.; and other plant parasitic nematode species;

Insects from the order Isoptera for example Calotermes flavicollis, Coptotermes spp. such as C. formosanus, C. gestroi, C. acinaciformis; Cornitermes cumulans, Cryptotermes spp. such as C. brevis, C. cavifrons; Globitermes sulfureus, Heterotermes spp. such as H. aureus, H. longiceps, H. tenuis; Leucotermes flavipes, Odontotermes spp., Incisitermes spp. such as I. minor, I. snyder; Marginitermes hubbardi, Mastotermes spp. such as M. darwiniensis Neocapritermes spp. such as N. opacus, N. parvus; Neotermes spp., Procornitermes spp., Zootermopsis spp. such as Z. angusticollis, Z. nevadensis, Reticulitermes spp. such as R. hesperus, R. tibialis, R. speratus, R. flavipes, R. grassei, R. lucifugus, R. santonensis, R. virginicus; Termes natalensis,

Insects from the order Blattaria for example Blatta spp. such as B. orientalis, B. lateralis; Blattella spp. such as B. asahinae, B. germanica; Leucophaea maderae, Panchlora nivea, Periplaneta spp. such as P. americana, P. australasiae, P. brunnea, P. fuligginosa, P. japonica; Supella longipalpa, Parcoblatta pennsylvanica, Eurycotis floridana, Pycnoscelus surinamensis,

Insects from the order Siphonoptera for example Cediopsylla simples, Ceratophyllus spp., Ctenocephalides spp. such as C. felis, C. canis, Xenopsylla cheopis, Pulex irritans, Trichodectes canis, Tunga penetrans, and Nosopsyllus fasciatus,

Insects from the order Thysanura for example Lepisma saccharina, Ctenolepisma urbana, and Thermobia domestica,

Pests from the class Chilopoda for example Geophilus spp., Scutigera spp. such as Scutigera coleoptrata;

Pests from the class Diplopoda for example Blaniulus guttulatus, Julus spp., Narceus spp.,

Pests from the class Symphyla for example Scutigerella immaculata,

Insects from the order Dermaptera, for example Forficula auricularia,

Insects from the order Collembola, for example Onychiurus spp., such as Onychiurus armatus,

Pests from the order Isopoda for example, Armadillidium vulgare, Oniscus asellus, Porcelllio scaber,

Insects from the order Phthiraptera, for example Damalinia spp., Pediculus spp. such as Pediculus humanus capitis, Pediculus humanus corporis, Pediculus humanus humanus; Pthirus pubis, Haematopinus spp. such as Haematopinus eurysternus, Haematopinus suis; Linognathus spp. such as Linognathus vituli; Bovicola bovis, Menopon gallinae, Menacanthus stramineus and Solenopotes capillatus, Trichodectes spp.,

Examples of further pest species which may be controlled by compounds of formula (I) include: from the Phylum Mollusca, class Bivalvia, for example, Dreissena spp.; class Gastropoda, for example, Arion spp., Biomphalaria spp., Bulinus spp., Deroceras spp., Galba spp., Lymnaea spp., Oncomelania spp., Pomacea canaliclata, Succinea spp.; from the class of the helminths, for example, Ancylostoma duodenale, Ancylostoma ceylanicum, Acylostoma braziliensis, Ancylostoma spp., Ascaris lumbricoides, Ascaris spp., Brugia malayi, Brugia timori, Bunostomum spp., Chabertia spp., Clonorchis spp., Cooperia spp., Dicrocoelium spp., Dictyocaulus filaria, Diphyllobothrium latum, Dracunculus medinensis, Echinococcus granulosus, Echinococcus multilocularis, Enterobius vermicularis, Faciola spp., Haemonchus spp. such as Haemonchus contortus; Heterakis spp., Hymenolepis nana, Hyostrongulus spp., Loa Loa, Nematodirus spp., Oesophagostomum spp., Opisthorchis spp., Onchocerca volvulus, Ostertagia spp., Paragonimus spp., Schistosomen spp., Strongyloides fuelleborni, Strongyloides stercoralis, Stronyloides spp., Taenia saginata, Taenia solium, Trichinella spiralis, Trichinella nativa, Trichinella britovi, Trichinella nelsoni, Trichinella pseudopsiralis, Trichostrongulus spp., Trichuris trichiura, Wuchereria bancrofti.

The compounds of the present invention are suitable for use in treating or protecting animals against infestation or infection by parasites. Therefore, the present invention also relates to the use of a compound of the present invention for the manufacture of a medicament for the treatment or protection of animals against infestation or infection by parasites. Furthermore, the present invention relates to a method of treating or protecting animals against infestation and infection by parasites, which comprises orally, topically or parenterally administering or applying to the animals a parasiticidally effective amount of a compound of the present invention.

The present invention also relates to the non-therapeutic use of compounds of the present invention for treating or protecting animals against infestation and infection by parasites. Moreover, the present invention relates to a non-therapeutic method of treating or protecting animals against infestation and infection by parasites, which comprises applying to a locus a parasiticidally effective amount of a compound of the present invention.

The compounds of the present invention are further suitable for use in combating or controlling parasites in and on animals. Furthermore, the present invention relates to a method of combating or controlling parasites in and on animals, which comprises contacting the parasites with a parasitically effective amount of a compound of the present invention.

The present invention also relates to the non-therapeutic use of compounds of the present invention for controlling or combating parasites. Moreover, the present invention relates to a non-therapeutic method of combating or controlling parasites, which comprises applying to a locus a parasiticidally effective amount of a compound of the present invention.

The compounds of the present invention can be effective through both contact (via soil, glass, wall, bed net, carpet, blankets or animal parts) and ingestion (e.g. baits). Furthermore, the compounds of the present invention can be applied to any and all developmental stages.

The compounds of the present invention can be applied as such or in form of compositions comprising the compounds of the present invention.

The compounds of the present invention can also be applied together with a mixing partner, which acts against pathogenic parasites, e.g. with synthetic coccidiosis compounds, polyetherantibiotics such as Amprolium, Robenidin, Toltrazuril, Monensin, Salinomycin, Maduramicin, Lasalocid, Narasin or Semduramicin, or with other mixing partners as defined above, or in form of compositions comprising said mixtures.

The compounds of the present invention and compositions comprising them can be applied orally, parenterally or topically, e.g. dermally. The compounds of the present invention can be systemically or non-systemically effective.

The application can be carried out prophylactically, therapeutically or non-therapeutically. Furthermore, the application can be carried out preventively to places at which occurrence of the parasites is expected.

As used herein, the term “contacting” includes both direct contact (applying the compounds/compositions directly on the parasite, including the application directly on the animal or excluding the application directly on the animal, e.g. at it's locus for the latter) and indirect contact (applying the compounds/compositions to the locus of the parasite). The contact of the parasite through application to its locus is an example of a non-therapeutic use of the compounds of the present invention.

The term “locus” means the habitat, food supply, breeding ground, area, material or environment in which a parasite is growing or may grow outside of the animal.

As used herein, the term “parasites” includes endo- and ectoparasites. In some embodiments of the present invention, endoparasites can be preferred. In other embodiments, ectoparasites can be preferred. Infestations in warm-blooded animals and fish include, but are not limited to, lice, biting lice, ticks, nasal bots, keds, biting flies, muscoid flies, flies, myiasitic fly larvae, chiggers, gnats, mosquitoes and fleas.

The compounds of the present invention are especially useful for combating parasites of the following orders and species, respectively:

fleas (Siphonaptera), e.g. Ctenocephalides felis, Ctenocephalides canis, Xenopsylla cheopis, Pulex irritans, Tunga penetrans, and Nosopsyllus fasciatus; cockroaches (Blattaria—Blattodea), e.g. Blattella germanica, Blattella asahinae, Periplaneta americana, Periplaneta japonica, Periplaneta brunnea, Periplaneta fuligginosa, Periplaneta australasiae, and Blatta orientalis; flies, mosquitoes (Diptera), e.g. Aedes aegypti, Aedes albopictus, Aedes vexans, Anastrepha ludens, Anopheles maculipennis, Anopheles crucians, Anopheles albimanus, Anopheles gambiae, Anopheles freeborni, Anopheles leucosphyrus, Anopheles minimus, Anopheles quadrimaculatus, Calliphora vicina, Chrysomya bezziana, Chrysomya hominivorax, Chrysomya macellaria, Chrysops discalis, Chrysops silacea, Chrysops atlanticus, Cochliomyia hominivorax, Cordylobia anthropophaga, Culicoides furens, Culex pipiens, Culex nigripalpus, Culex quinquefasciatus, Culex tarsalis, Culiseta inornata, Culiseta melanura, Dermatobia hominis, Fannia canicularis, Gasterophilus intestinalis, Glossina morsitans, Glossina palpalis, Glossina fuscipes, Glossina tachinoides, Haematobia irritans, Haplodiplosis equestris, Hippelates spp., Hypoderma lineata, Leptoconops torrens, Lucilia caprina, Lucilia cuprina, Lucilia sericata, Lycoria pectoralis, Mansonia spp., Musca domestica, Muscina stabulans, Oestrus ovis, Phlebotomus argentipes, Psorophora columbiae, Psorophora discolor, Prosimulium mixtum, Sarcophaga haemorrhoidalis, Sarcophaga sp., Simulium vittatum, Stomoxys calcitrans, Tabanus bovinus, Tabanus atratus, Tabanus lineola, and Tabanus similis; lice (Phthiraptera), e.g. Pediculus humanus capitis, Pediculus humanus corporis, Pthirus pubis, Haematopinus eurysternus, Haematopinus suis, Linognathus vituli, Bovicola bovis, Menopon gallinae, Menacanthus stramineus and Solenopotes capillatus; ticks and parasitic mites (Parasitiformes): ticks (Ixodida), e.g. Ixodes scapularis, Ixodes holocyclus, Ixodes pacificus, Rhiphicephalus sanguineus, Dermacentor andersoni, Dermacentor variabilis, Amblyomma americanum, Ambryomma maculatum, Ornithodorus hermsi, Ornithodorus turicata and parasitic mites (Mesostigmata), e.g. Ornithonyssus bacoti and Dermanyssus gallinae; Actinedida (Prostigmata) und Acaridida (Astigmata), e.g. Acarapis spp., Cheyletiella spp., Ornithocheyletia spp., Myobia spp., Psorergates spp., Demodex spp., Trombicula spp., Listrophorus spp., Acarus spp., Tyrophagus spp., Caloglyphus spp., Hypodectes spp., Pterolichus spp., Psoroptes spp., Chorioptes spp., Otodectes spp., Sarcoptes spp., Notoedres spp.,Knemidocoptes spp., Cytodites spp., and Laminosioptes spp; Bugs (Heteropterida): Cimex lectularius, Cimex hemipterus, Reduvius senilis, Triatoma spp., Rhodnius ssp., Panstrongylus ssp., and Arilus critatus; Anoplurida, e.g. Haematopinus spp., Linognathus spp., Pediculus spp., Phtirus spp., and Solenopotes spp.; Mallophagida (suborders Arnblycerina and Ischnocerina), e.g. Trimenopon spp., Menopon spp., Trinoton spp., Bovicola spp., Werneckiella spp., Lepikentron spp., Trichodectes spp., and Felicola spp.; Roundworms Nematoda: Wipeworms and Trichinosis (Trichosyringida), e.g. Trichinellidae (Trichinella spp.), (Trichuridae) Trichuris spp., Capillaria spp.; Rhabditida, e.g. Rhabditis spp., Strongyloides spp., Helicephalobus spp.; Strongylida, e.g. Strongylus spp., Ancylostoma spp., Necator americanus, Bunostomum spp. (Hookworm), Trichostrongylus spp., Haemonchus contortus, Ostertagia spp., Cooperia spp., Nematodirus spp., Dictyocaulus spp., Cyathostoma spp., Oesophagostomum spp., Stephanurus dentatus, Ollulanus spp., Chabertia spp., Stephanurus dentatus, Syngamus trachea, Ancylostoma spp., Uncinaria spp., Globocephalus spp., Necator spp., Metastrongylus spp., Muellerius capillaris, Protostrongylus spp., Angiostrongylus spp., Parelaphostrongylus spp., Aleurostrongylus abstrusus, and Dioctophyma renale; Intestinal roundworms (Ascaridida), e.g. Ascaris lumbricoides, Ascaris suum, Ascaridia galli, Parascaris equorum, Enterobius vermicularis (Threadworm), Toxocara canis, Toxascaris leonine, Skrjabinema spp., and Oxyuris equi; Camallanida, e.g. Dracunculus medinensis (guinea worm); Spirurida, e.g. Thelazia spp., Wuchereria spp., Brugia spp., Onchocerca spp., Dirofilari spp.a, Dipetalonema spp., Setaria spp., Elaeophora spp., Spirocerca lupi, and Habronema spp.; Thorny headed worms (Acanthocephala), e.g. Acanthocephalus spp., Macracanthorhynchus hirudinaceus and Oncicola spp.; Planarians (Plathelminthes): Flukes (Trematoda), e.g. Faciola spp., Fascioloides magna, Paragonimus spp., Dicrocoelium spp., Fasciolopsis buski, Clonorchis sinensis, Schistosoma spp., Trichobilharzia spp., Alaria alata, Paragonimus spp., and Nanocyetes spp.; Cercomeromorpha, in particular Cestoda (Tapeworms), e.g. Diphyllobothrium spp., Tenia spp., Echinococcus spp., Dipylidium caninum, Multiceps spp., Hymenolepis spp., Mesocestoides spp., Vampirolepis spp., Moniezia spp., Anoplocephala spp., Sirometra spp., Anoplocephala spp., and Hymenolepis spp.

As used herein, the term “animal” includes warm-blooded animals (including humans) and fish. Preferred are mammals, such as cattle, sheep, swine, camels, deer, horses, pigs, poultry, rabbits, goats, dogs and cats, water buffalo, donkeys, fallow deer and reindeer, and also in fur-bearing animals such as mink, chinchilla and raccoon, birds such as hens, geese, turkeys and ducks and fish such as fresh- and salt-water fish such as trout, carp and eels. Particularly preferred are domestic animals, such as dogs or cats.

In general, “parasiticidally effective amount” means the amount of active ingredient needed to achieve an observable effect on growth, including the effects of necrosis, death, retardation, prevention, and removal, destruction, or otherwise diminishing the occurrence and activity of the target organism. The parasiticidally effective amount can vary for the various compounds/compositions used in the invention. A parasiticidally effective amount of the compositions will also vary according to the prevailing conditions such as desired parasiticidal effect and duration, target species, mode of application, and the like.

Generally, it is favorable to apply the compounds of the present invention in total amounts of 0.5 mg/kg to 100 mg/kg per day, preferably 1 mg/kg to 50 mg/kg per day.

For oral administration to warm-blooded animals, the formula I compounds may be formulated as animal feeds, animal feed premixes, animal feed concentrates, pills, solutions, pastes, suspensions, drenches, gels, tablets, boluses and capsules. In addition, the formula I compounds may be administered to the animals in their drinking water. For oral administration, the dosage form chosen should provide the animal with 0.01 mg/kg to 100 mg/kg of animal body weight per day of the formula I compound, preferably with 0.5 mg/kg to 100 mg/kg of animal body weight per day.

Alternatively, the formula I compounds may be administered to animals parenterally, for example, by intraruminal, intramuscular, intravenous or subcutaneous injection. The formula I compounds may be dispersed or dissolved in a physiologically acceptable carrier for subcutaneous injection. Alternatively, the formula I compounds may be formulated into an implant for subcutaneous administration. In addition the formula I compound may be transdermally administered to animals. For parenteral administration, the dosage form chosen should provide the animal with 0.01 mg/kg to 100 mg/kg of animal body weight per day of the formula I compound.

The formula I compounds may also be applied topically to the animals in the form of dips, dusts, powders, collars, medallions, sprays, shampoos, spot-on and pour-on formulations and in ointments or oil-in-water or water-in-oil emulsions. For topical application, dips and sprays usually contain 0.5 ppm to 5,000 ppm and preferably 1 ppm to 3,000 ppm of the formula I compound. In addition, the formula I compounds may be formulated as ear tags for animals, particularly quadrupeds such as cattle and sheep.

Suitable preparations are:

-   -   Solutions such as oral solutions, concentrates for oral         administration after dilution, solutions for use on the skin or         in body cavities, pouring-on formulations, gels;     -   Emulsions and suspensions for oral or dermal administration;         semi-solid preparations;     -   Formulations wherein the active compound is processed in an         ointment base or in an oil-in-water or water-in-oil emulsion         base;     -   Solid preparations such as powders, premixes or concentrates,         granules, pellets, tablets, boluses, capsules; aerosols and         inhalants, and active compound-containing shaped articles.

Compositions suitable for injection are prepared by dissolving the active ingredient in a suitable solvent and optionally adding further auxiliaries such as acids, bases, buffer salts, preservatives, and solubilizers. Suitable auxiliaries for injection solutions are known in the art. The solutions are filtered and filled sterile.

Oral solutions are administered directly. Concentrates are administered orally after prior dilution to the use concentration. Oral solutions and concentrates are prepared according to the state of the art and as described above for injection solutions, sterile procedures not being necessary.

Solutions for use on the skin are trickled on, spread on, rubbed in, sprinkled on or sprayed on. Solutions for use on the skin are prepared according to the state of the art and according to what is described above for injection solutions, sterile procedures not being necessary.

Gels are applied to or spread on the skin or introduced into body cavities. Gels are prepared by treating solutions which have been prepared as described in the case of the injection solutions with sufficient thickener that a clear material having an ointment-like consistency results. Suitable thickeners are known in the art.

Pour-on formulations are poured or sprayed onto limited areas of the skin, the active compound penetrating the skin and acting systemically. Pour-on formulations are prepared by dissolving, suspending or emulsifying the active compound in suitable skin-compatible solvents or solvent mixtures. If appropriate, other auxiliaries such as colorants, bioabsorption-promoting substances, antioxidants, light stabilizers, adhesives are added. Suitable such auxiliaries are known in the art.

Emulsions can be administered orally, dermally or as injections. Emulsions are either of the water-in-oil type or of the oil-in-water type. They are prepared by dissolving the active compound either in the hydrophobic or in the hydrophilic phase and homogenizing this with the solvent of the other phase with the aid of suitable emulsifiers and, if appropriate, other auxiliaries such as colorants, absorption-promoting substances, preservatives, antioxidants, light stabilizers, viscosity-enhancing substances. Suitable hydrophobic phases (oils), suitable hydrophilic phases, suitable emulsifiers, and suitable further auxiliaries for emulsions are known in the art.

Suspensions can be administered orally or topically/dermally. They are prepared by suspending the active compound in a suspending agent, if appropriate with addition of other auxiliaries such as wetting agents, colorants, bioabsorption-promoting substances, preservatives, antioxidants, light stabilizers. Suitable suspending agents, and suitable other auxiliaries for suspensions including wetting agents are known in the art.

Semi-solid preparations can be administered orally or topically/dermally. They differ from the suspensions and emulsions described above only by their higher viscosity.

For the production of solid preparations, the active compound is mixed with suitable excipients, if appropriate with addition of auxiliaries, and brought into the desired form. Suitable auxiliaries for this purpose are known in the art.

The compositions which can be used in the invention can comprise generally from about 0.001 to 95% of the compound of the present invention.

Ready-to-use preparations contain the compounds acting against parasites, preferably ectoparasites, in concentrations of 10 ppm to 80 percent by weight, preferably from 0.1 to 65 percent by weight, more preferably from 1 to 50 percent by weight, most preferably from 5 to 40 percent by weight.

Preparations which are diluted before use contain the compounds acting against ectoparasites in concentrations of 0.5 to 90 percent by weight, preferably of 1 to 50 percent by weight.

Furthermore, the preparations comprise the compounds of formula I against endoparasites in concentrations of 10 ppm to 2 percent by weight, preferably of 0.05 to 0.9 percent by weight, very particularly preferably of 0.005 to 0.25 percent by weight.

Topical application may be conducted with compound-containing shaped articles such as collars, medallions, ear tags, bands for fixing at body parts, and adhesive strips and foils.

Generally it is favorable to apply solid formulations which release compounds of the present invention in total amounts of 10 mg/kg to 300 mg/kg, preferably 20 mg/kg to 200 mg/kg, most preferably 25 mg/kg to 160 mg/kg body weight of the treated animal in the course of three weeks.

EXAMPLES

With appropriate modification of the starting materials, the procedures as described in the preparation examples below were used to obtain further compounds of formula I. The compounds obtained in this manner are listed in the table that follows, together with physical data.

Compounds can be characterized e.g. by coupled High Performance Liquid Chromatography/mass spectrometry (HPLC/MS), by ¹H-NMR and/or by their melting points.

Analytical HPLC/MS—Method 1: Agilent Eclipse Plus C18, 50×4.6 mm, ID 5 μm; Elution: A=10 mM Amm. Formate (0.1% Formic Acid), B=Acetonitrile (0.1% Formic Acid), Flow=1.25 ml/min. at 40° C.; Gradient: 10% B to 100% B—1.5 min, hold for 1 min, 1 min—100% B. Run Time=3.5 min.

Analytical HPLC/MS—Method 2: Kinetex XB C18 1.7μ 50×2.1 mm; A=Water+0.1% TFA, B=Acetonitrile, Flow=0.8 ml/min-1.0 ml/min in 1.5 min. at 60° C.; Gradient: 5% B to 100% B—1.5 min.

¹H-NMR: The signals are characterized by chemical shift (ppm, δ[delta]) vs. tetramethylsilane respectively, CDCl₃ for ¹³C-NMR, by their multiplicity and by their integral (relative number of hydrogen atoms given). The following abbreviations are used to characterize the multiplicity of the signals: m=multiplet, h=heptet, q=quartet, t=triplet, d=doublet and s=singlet.

Abbreviations used are: d for day(s), h for hour(s), min for minute(s), r.t./room temperature for 20-25° C., R_(t) for retention time; DMSO for dimethyl sulfoxide, OAc for acetate, EtOAc for ethyl acetate, THE for tetrahydrofuran, t-BuOH for tert-butanol, dppfPdCl for [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium(II), DIPEA for diisopropylethylamine, DCM for dichloromethane and DMAP for 4-Dimethylaminopyridine

Preparation Examples Example C-1: 6-[(E)-[(2-isopropylphenyl)carbamothioylhydrazono]methyl]-N-[4-(trifluoromethoxy)phenyl]isoquinoline-1-carboxamide (C-1) Step 1: 6-bromo-N-[4-(trifluoromethoxy)phenyl]isoquinoline-1-carboxamide

To a stirred solution of 6-bromoisoquinoline-1-carboxylic acid (1.68 g) and 4-(trifluoromethoxy)aniline (1.2 g) in CH₂Cl₂ (20 mL) were added EDCl (1.53 g) and DMAP (0.81 g) and the reaction mixture was stirred at r.t. for 16 h. An additional portion of and 4-(trifluoromethoxy)aniline (0.9 mL) and EDCl (0.2 g) were added and the reaction was stirred for an additional 20 h. The reaction mixture was then quenched with a solution of aq. HCl (1 M) then extracted with CH₂Cl₂. The organic phase was dried over MgSO₄, filtered and concentrated and used without further purification (2.5 g). LC/MS (method 1): Rt: 1.47 min; MS: m/z=410 (M+).

Step 2: 6-[(E)-prop-1-enyl]-N-[4-(trifluoromethoxy)phenyl]isoquinoline-1-carboxamide

A stirred suspension of 6-bromo-N-[4-(trifluoromethoxy)phenyl]isoquinoline-1-carboxamide (2.5 g, 6.1 mmol), [(E)-prop-1-enyl]boronic acid (0.79 g), dppfPdCl₂ (0.22 g), K₂CO₃ (1.69 g) in DME/H₂O (25 mL, 2:1) was heated at 110° C. for 16 h. The reaction mixture was allowed to cool to r.t. then extracted with EtOAc. The organic phase was dried over MgSO4, filtered and concentrated. Purification by silica gel chromatography eluting with a gradient of CH/EE afforded the title compound (2.0 g). LC/MS (method 1): Rt: 1.54 min; MS: m/z=373 (M+).

Step 3: 6-formyl-N-[4-(trifluoromethoxy)phenyl]isoquinoline-1-carboxamide

To a stirred solution of 6-[(E)-prop-1-enyl]-N-[4-(trifluoromethoxy)phenyl]isoquinoline-1-carboxamide (2.0 g) and OsO₄ (1.3 mL, 2.5% in t-BuOH) in THE/H₂O (80 mL, 1:1) at 0° C. was added NaIO₄ (2.3 g) and the reaction mixture was stirred from 0° C. to r.t. over 16 h. The reaction mixture was then diluted with water and a saturated solution of NaS₂O₃ (100 mL) then extracted with EtOAc. The organic phase was dried over MgSO4, filtered and concentrated and the resultant crude material was purified by trituration with diisopropyl ether to afford 6-formyl-N-[4-(trifluoromethoxy)phenyl]isoquinoline-1-carboxamide (1.55 g, 80% yield). LC/MS (method 1): Rt: 1.27 min; MS: m/z=361 (M+).

Step 4: 6-[(E)-[(2-isopropylphenyl)carbamothioylhydrazono]methyl]-N-[4-(trifluoromethoxy)phenyl]isoquinoline-1-carboxamide

A solution of 6-formyl-N-[4-(trifluoromethoxy)phenyl]isoquinoline-1-carboxamide (1.55 g) and 1-amino-3-(2-isopropylphenyl)thiourea (1.1 g) in EtOH (30 mL) was stirred at 60° C. for 4 h. The reaction mixture was then allowed to cool to r.t. and the crude product was isolated by filtration and purified by trituration with diisopropyl ether to afford 6-[(E)-[(2-isopropylphenyl)carbamothioylhydrazono]methyl]-N-[4-(trifluoromethoxy)phenyl]isoquinoline-1-carboxamide (C-1) (1.81 g, 76% yield). LC/MS (method 1): Rt: 1.45 min; MS: m/z=552 (M+). ¹H NMR (400 MHz, THF-d₈) δ 11.13 (s, 1H), 10.66 (s, 1H), 9.63-9.55 (m, 2H), 8.58 (d, J=5.5 Hz, 1H), 8.36 (dd, J=9.2, 1.7 Hz, 1H), 8.18 (d, J=2.6 Hz, 2H), 8.07-7.93 (m, 3H), 7.42 (dd, J=7.8, 1.4 Hz, 1H), 7.36-7.25 (m, 3H), 7.25-7.12 (m, 2H), 3.58 (dp, J=2.3, 1.1 Hz, 6H), 3.26 (p, J=6.9 Hz, 1H), 2.51 (s, 4H), 1.72 (pt, J=2.0, 0.9 Hz, 8H), 1.27 (d, J=6.9 Hz, 6H).

Example C-2: 6-[(E)-[(Z)-[3-(2-isopropylphenyl)-4-oxo-thiazolidin-2-ylidene]hydrazono]methyl]-N-[4-(trifluoromethoxy)phenyl]isoquinoline-1-carboxamide

A solution of 6-[(E)-[(2-isopropylphenyl)carbamothioylhydrazono]methyl]-N-[4-(trifluoromethoxy)phenyl]isoquinoline-1-carboxamide (C-1) (1.65 g), methyl bromoacetate (0.59 mL) and NaOAc (0.98 g) in EtOH (100 mL) was stirred at 50° C. for 16 h. The resultant precipate was isolated by filtration to afford 6-[(E)-[(Z)-[3-(2-isopropylphenyl)-4-oxo-thiazolidin-2-ylidene]hydrazono]methyl]-N-[4-(trifluoromethoxy)phenyl]isoquinoline-1-carboxamide (1.44 g, 81% yield). LC/MS (method 1): Rt: 1.49 min; MS: m/z=592 (M+). ¹H NMR (400 MHz, THE-d₈) δ 10.65 (s, 1H), 9.60 (dd, J=9.2, 0.9 Hz, 1H), 8.57 (d, J=5.5 Hz, 1H), 8.24 (dd, J=9.1, 1.7 Hz, 1H), 8.13-8.08 (m, 1H), 8.07-7.96 (m, 3H), 7.50-7.37 (m, 2H), 7.28 (ddd, J=14.8, 7.5, 1.3 Hz, 3H), 7.16 (dd, J=7.9, 1.3 Hz, 1H), 4.14-3.99 (m, 2H), 3.57 (dq, J=2.2, 1.1 Hz, 6H), 2.88 (hept, J=6.9 Hz, 1H), 2.51 (s, 5H), 1.72 (ddp, J=3.1, 2.0, 1.0 Hz, 8H), 1.20 (dd, J=7.9, 6.9 Hz, 6H).

Comp Ar

A¹ A² A³ B¹ B² B³ R¹ t_(R) (min) M+ (m/z) C-1

CH CH N CH CH CH

1.472 552.1 C-2

CH CH N CH CH CH

1.509 592.1 C-3

N CH N CH CH CH

1.144 539.1 C-4

N CH N CH CH CH

1.082 578.9 C-5

N CH N CH CH CH

1.026 551.2 C-6

N CH N CH CH CH

2.037 538 C-7

N CH N CH CH CH

2.123 580.2 C-8

N CH N CH CH CH

2.069 577.9 C-9

CH N N CH CH CH

1.367 553  C-10

CH N N CH CH CH

1.392 593.1  C-11

CH N N CH CH CH

1.425 593  C-12

CH N N CH CH CH

1.403 567.2  C-13

CH N N CH CH CH

1.273 565.2  C-14

CH N N CH CH CH

1.425 607.1

Biological Examples

If not otherwise specified, the test solutions are prepared as follows:

The active compound is dissolved at the desired concentration in a mixture of 1:1 (vol:vol) distilled water:acetone. The test solution is prepared at the day of use.

Test solutions are prepared in general at concentrations of 1000 ppm, 500 ppm, 300 ppm, 100 ppm and 30 ppm (wt/vol).

B.1. Boll Weevil (Anthonomus grandis)

For evaluating control of boll weevil (Anthonomus grandis) the test unit consisted of 96-well-microtiter plates containing an insect diet and 5-10 A. grandis eggs.

The compounds were formulated using a solution containing 75% v/v water and 25% v/v DMSO. Different concentrations of formulated compounds were sprayed onto the insect diet at 5 μl, using a custom built micro atomizer, at two replications.

After application, microtiter plates were incubated at about 25±1° C. and about 75±5% relative humidity for 5 days. Egg and larval mortality was then visually assessed.

In this test, the following compounds at 800 ppm showed over 75% mortality in comparison with untreated controls: C-1, C-2, C-3.

B.2. Diamond Back Moth (Plutella xylostella)

The active compound is dissolved at the desired concentration in a mixture of 1:1 (vol:vol) distilled water:acetone. Surfactant (Alkamuls® EL 620) is added at a rate of 0.1% (vol/vol). The test solution is prepared at the day of use.

Leaves of cabbage were dipped in test solution and air-dried. Treated leaves were placed in petri dish enlined with moist filter paper and inoculated with ten 3^(rd) instar larvae. Mortality was recorded 72 hours after treatment. Feeding damages were also recorded using a scale of 0-100%.

In this test, the following compounds at 300 ppm showed over 75% mortality in comparison with untreated controls: C-1, C-2, C-3, C-4, C-6, C-8, C-9, C-10, C-11, C-12, C-13, C-14.

B.3 Silverleaf Whitefly (Bemisia argentifolii) (Adults)

The active compounds were formulated in cyclohexanone as a 10,000 ppm solution supplied in tubes. The tubes were inserted into an automated electrostatic sprayer equipped with an atomizing nozzle and they served as stock solutions for which lower dilutions were made in 50% acetone:50% water (v/v). A non-ionic surfactant (Kinetic®) was included in the solution at a volume of 0.01% (v/v).

Cotton plants at the cotyledon stage (one plant per pot) were sprayed by an automated electrostatic plant sprayer equipped with an atomizing spray nozzle. The plants were dried in the sprayer fume hood and then removed from the sprayer. Each pot was placed into a plastic cup and about 10 to 12 whitefly adults (approximately 3-5 days old) were introduced. The insects were collected using an aspirator and a nontoxic Tygon® tubing connected to a barrier pipette tip. The tip, containing the collected insects, was then gently inserted into the soil containing the treated plant, allowing insects to crawl out of the tip to reach the foliage for feeding. Cups were covered with a reusable screened lid. Test plants were maintained in a growth room at about 25° C. and about 20-40% relative humidity for 3 days, avoiding direct exposure to fluorescent light (24-hour photoperiod) to prevent trapping of heat inside the cup. Mortality was assessed 3 days after treatment, compared to untreated control plants.

In this test, the following compounds at 300 ppm showed over 75% mortality in comparison with untreated controls: C-2.

B.4. Southern Armyworm (Spodoptera eridania), 2nd Instar Larvae

The active compounds were formulated in cyclohexanone as a 10,000 ppm solution supplied in tubes. The tubes were inserted into an automated electrostatic sprayer equipped with an atomizing nozzle and they served as stock solutions for which lower dilutions were made in 50% acetone:50% water (v/v). A nonionic surfactant (Kinetic®) was included in the solution at a volume of 0.01% (v/v).

Lima bean plants (variety Sieva) were grown 2 plants to a pot and selected for treatment at the 1^(st) true leaf stage. Test solutions were sprayed onto the foliage by an automated electrostatic plant sprayer equipped with an atomizing spray nozzle. The plants were dried in the sprayer fume hood and then removed from the sprayer. Each pot was placed into perforated plastic bags with a zip closure. About 10 to 11 armyworm larvae were placed into the bag and the bags zipped closed. Test plants were maintained in a growth room at about 25° C. and about 20-40% relative humidity for 4 days, avoiding direct exposure to fluorescent light (24 hour photoperiod) to prevent trapping of heat inside the bags. Mortality and reduced feeding were assessed 4 days after treatment, compared to untreated control plants.

In this test, the following compounds at 300 ppm showed over 75% mortality in comparison with untreated controls: C-1, C-2.

B.5. Tobacco Budworm (Heliothis virescens)

For evaluating control of tobacco budworm (Heliothis virescens) the test unit consisted of 96-well-microtiter plates containing an insect diet and 15-25 H. virescens eggs.

The compounds were formulated using a solution containing 75% v/v water and 25% v/v DMSO. Different concentrations of formulated compounds were sprayed onto the insect diet at 10 μl, using a custom built micro atomizer, at two replications.

After application, microtiter plates were incubated at about 28±1° C. and about 80±5% relative humidity for 5 days. Egg and larval mortality was then visually assessed.

In this test, the following compounds at 800 ppm showed over 75% mortality in comparison with untreated controls: C-1, C-2, C-3, C-6, C-7, C-8, C-9, C-10, C-11, C-12, C-13, C-14.

B.6. Yellow Fever Mosquito (Aedes aegypti)

For evaluating control of yellow fever mosquito (Aedes aegypti) the test unit consisted of 96-well-microtiter plates containing 200 μl of tap water per well and 5-15 freshly hatched A. aegypti larvae. The active compounds were formulated using a solution containing 75% (v/v) water and 25% (v/v) DMSO. Different concentrations of formulated compounds or mixtures were sprayed onto the insect diet at 2.5 μl, using a custom built micro atomizer, at two replications.

After application, microtiter plates were incubated at 28+1° C., 80+5% RH for 2 days. Larval mortality was then visually assessed.

In this test, the following compounds at 800 ppm showed over 75% mortality in comparison with untreated controls: C-1, C-2, C-9, C-10, C-11, C-13, C-14.

B.7. Orchid Thrips (Dichromothrips corbetti)

Dichromothrips corbetti adults used for bioassay were obtained from a colony maintained continuously under laboratory conditions. For testing purposes, the test compound is diluted in a 1:1 mixture of acetone:water (vol:vol), plus Kinetic® HV at a rate of 0.01% v/v.

Thrips potency of each compound was evaluated by using a floral-immersion technique. All petals of individual, intact orchid flowers were dipped into treatment solution and allowed to dry in Petri dishes. Treated petals were placed into individual re-sealable plastic along with about 20 adult thrips. All test arenas were held under continuous light and a temperature of about 28° C. for duration of the assay. After 3 days, the numbers of live thrips were counted on each petal. The percent mortality was recorded 72 hours after treatment.

In this test, the following compounds at 300 ppm showed over 75% mortality in comparison with untreated controls: C-1, C-2, C-10, C-11, C-12, C-13, C-14.

B.9. Western Flower Thrips (Frankliniella occidentalis)

The active compounds were formulated by a Tecan liquid handler in 100% cyclohexanone as a 10,000 ppm solution supplied in tubes. The 10,000 ppm solution was serially diluted in 100% cyclohexanone to make interim solutions. These served as stock solutions for which final dilutions were made by the Tecan in 50% acetone:50% water (v/v) into 10 or 20 ml glass vials. A nonionic surfactant (Kinetic®) was included in the solution at a volume of 0.01% (v/v). The vials were then inserted into an automated electrostatic sprayer equipped with an atomizing nozzle for application to plants/insects.

Small (˜2″ in height) cotton plants are sprayed with test compounds at concentrations ranging from 300 to 0.01 ppm in acetone/water through the automated VPS. After drying, cotton leaves are removed and circular leaf discs (−1 cm diameter) are punched from the treated surface and transferred to clean 20 mL scintillation vials. Ten Western flower thrips (FRANOC) are aspirated into each scintillation vial. The vials with the leaf discs and thrips are kept in an upright incubator at 25° C. and 50% relative humidity with a 14:10 light:dark photoperiod. Each treatment is replicated twice.

Thrips mortality is assessed at 2 DAT (days after treatment), counting all thrips both dead and alive. [The average absolute mortality is calculated for each treatment.]

In this test, the following compounds at 300 ppm showed over 75% mortality in comparison with untreated controls: C-1, C-2, C-10. 

1. Compounds A compound of formula I

wherein A¹ is N or CR^(A1); A² is N or CR^(A2); A³ is N or CR^(A3); wherein at least one of the A¹, A², A³ is N; B¹ is CR^(B1); B² is CR^(B2); B³ is CR^(B3); R^(A1), R^(A2), and R^(A3) independently of each other are selected from H, halogen, N₃, OH, CN, NO₂, —SCN, —SF₅, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, tri-C₁-C₆-alkylsilyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₁-C₆-alkoxy-C₁-C₄-alkoxy, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkoxy, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₁-C₄-alkyl-C₃-C₆-cycloalkoxy, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,  C(═O)—OR^(a), NR^(b)R^(c), C₁-C₆-alkylene-NR^(b)R^(c), O—C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN, NH—C₁-C₆-alkylene-NR^(b)R^(c), C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), or S(═O)_(m)R^(e), phenyl, phenoxy, phenylcarbonyl, phenylthio, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f); R^(B1), R^(B2), and R^(B3), independently of each other are H, halogen, N₃, OH, CN, NO₂, —SCN, —SF₅, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, tri-C₁-C₆-alkylsilyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₁-C₆-alkoxy-C₁-C₄-alkoxy, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkoxy, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₁-C₄-alkyl-C₃-C₆-cycloalkoxy, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,  C(═O)—OR^(a), NR^(b)R^(c), C₁-C₆-alkylene-NR^(b)R^(c), O—C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN, NH—C₁-C₆-alkylene-NR^(b)R^(c), C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), or S(═O)_(m)R^(e), phenyl, phenoxy, phenylcarbonyl, phenylthio, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f); Q is —N═C(X)—, —N(R²)—C(═NR)—, or —N(R²)—C(═S)—, —C(R⁴R⁵)—O—, —C(═O)—O—, —S(═O)_(m)—C(R⁷R⁸)—, —N(R²)—S(═O)_(m)—, —N(R²)—C(R⁹R¹⁰)—, —C(═O)—C(R¹⁹R²⁰)—, —N(R²)—C(═O)—, —C(R¹³R¹⁴)—C(R¹⁵R¹⁶)—, or —C(R¹⁷)═C(R¹⁸)—; wherein Ar is bound to either side of Q; X is identical or different, H, halogen, SR⁷, OR⁸, N(R³)₂, —CR⁴═N(OCH₃), CN, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₃-C₆-cycloalkyl, wherein the alkyl, alkenyl, alkynyl and cycloalkyl moieties are unsubstituted or substituted with halogen; phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f); R is identical or different, H, CN, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₃-C₆-cycloalkyl, wherein the alkyl, alkenyl, alkynyl and cycloalkyl moieties are unsubstituted or substituted with halogen,  SR⁷, OR⁸, N(R³)₂, phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f); R² is H, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,  C(O)—OR^(a), C₁-C₆-alkylen-NR^(b)R^(c), C₁-C₆-alkylen-CN, C(O)—NR^(b)R^(c), C(O)—R^(d), SO₂NR^(b)R^(c), S(═O)_(m)R^(e), phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f); R³ is H, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, or C₃-C₆-cycloalkoxy-C₁-C₄-alkyl, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,  C₁-C₆-alkylene-CN, phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f); R⁴, R⁵, R⁷, R⁸, R⁹, R¹⁰, R¹³, R¹⁴, R¹⁵, R¹⁶, R¹⁷, R¹⁸, R¹⁹, R²⁰ are, identical or different, H, halogen, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,  C(═O)—OR^(a), C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN, C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), S(═O)_(m)R^(e), phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f); R⁶ is H, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,  C(═O)—OR^(a), C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN, C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), S(═O)_(m)R^(e), phenyl, —CH₂—C(═O)—OR^(a), or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f); Ar is phenyl or 5- or 6-membered hetaryl, which are unsubstituted or substituted with R^(Ar), wherein R^(Ar) is halogen, N₃, OH, CN, NO₂, —SCN, —SF₅, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, tri-C₁-C₆-alkylsilyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₁-C₆-alkoxy-C₁-C₄-alkoxy, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkoxy, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,  C(═O)—OR^(a), NR^(b)R^(c), C₁-C₆-alkylene-NR^(b)R^(c), O—C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN, NH—C₁-C₆-alkylene-NR^(b)R^(c), C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), or S(═O)_(m)R^(e), phenyl, phenoxy, phenylcarbonyl, phenylthio or —CH₂-phenyl, wherein phenyl rings are unsubstituted or substituted with R^(f); R¹ is a moiety of formula Y—Z-T-R¹¹ or Y—Z-T-R¹²; wherein Y is —CR^(ya)═N—, wherein the N is bound to Z; —NR^(yc)—C(═O)—, wherein C(═O) is bound to Z; or —NR^(yc)—C(═S)—, wherein C(═S) is bound to Z; Z is a single bond; —NR^(zc)—C(═O)—, wherein C(═O) is bound to T; —NR^(zc)—C(═S)—, wherein C(═S) is bound to T; —N═C(S—R^(za))—, wherein T is bound to the carbon atom; —O—C(═O)—, wherein T is bound to the carbon atom; or —NR^(zc)—C(S—R^(za))═, wherein T is bound to the carbon atom; T is O, N or N—R^(T); R¹¹ is C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₁-C₄-alkyl-C₃-C₆-cycloalkoxy, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,  C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN, C(═O)—NR^(b)R^(c), C(═O)—R^(d), aryl, aryl-carbonyl, aryl-C₁-C₄-alkyl, aryloxy-C₁-C₄-alkyl, heteroaryl, carbonyl-heteroaryl, heteroaryl-C₁-C₄-alkyl or heteroaryloxy-C₁-C₄-alkyl, wherein the phenyl rings are unsubstituted or substituted with R^(g) and wherein the heteroaryl is a 5- or 6-membered monocyclic heteroaryl or a 8-, 9- or 10-membered bicyclic heteroaryl; R¹² is a radical of the formula A¹;

wherein # indicates the point of attachment to T; R¹²¹, R¹²², R¹²³ are, identical or different, H, halogen, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyloxy, C₂-C₆-alkynyloxy, C₁-C₆-alkoxy-C₁-C₄-alkoxy, C₁-C₆-alkylcarbonlyoxy, C₁-C₆-alkenylcarbonlyoxy, C₃-C₆-cycloalkylcarbonlyoxy, wherein the alkyl, alkoxy, alkenyl, alkenyloxy, alkynyl, alkynyloxy and cycloalkyl moieties are unsubstituted or substituted with halogen, or NR^(b)R^(c), or one of R¹²¹, R¹²², R¹²³ may also be oxo; R¹²⁴ is H, C₁-C₆-alkyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₁-C₆-alkoxy, or C₂-C₆-alkenyloxy, wherein the alkyl, alkoxy, alkenyl and alkenyloxy moieties are unsubstituted or substituted with halogen; and where R^(ya) is H, halogen, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl, C₁-C₄-alkyl-C₃-C₆-cycloalkyl, C₁-C₄-alkyl-C₃-C₆-cycloalkoxy, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,  C(═O)—OR^(a), C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN, C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), S(═O)_(m)R^(e), phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f); R^(yc), R^(zc) are, identical or different, H, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₄-alkyl-C₁-C₆-alkoxy, C₃-C₆-cycloalkyl, C₁-C₄-alkyl-C₃-C₆-cycloalkyl, or C₁-C₄-alkyl-C₃-C₆-cycloalkoxy, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen; R^(T) is H, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₄-alkyl-C₁-C₆-alkoxy, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,  C(═O)—OR^(a), C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN, C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), S(═O)_(m)R^(e), phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f); R^(zc) together with R^(T) if present, may form C₁-C₆-alkylene or a linear C₂-C₆-alkenylene group, where in the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene a CH₂ moiety may be replaced by a carbonyl or a C═N—R′ and/or wherein 1 or 2 CH₂ moieties may be replaced by O or S and/or wherein the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene may be unsubstituted or substituted with R^(h); R^(za) is H, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, tri-C₁-C₆-alkylsilyl, C₂-C₆-alkynyl, C₁-C₄-alkyl-C₁-C₆-alkoxy, C₃-C₆-cycloalkyl, C₁-C₄-alkyl-C₃-C₆-cycloalkoxy, C₁-C₄-alkyl-C₃-C₆-cycloalkyl, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,  C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN, C(═O)—NR^(b)R^(c), C(═O)—R^(d), phenyl, phenylcarbonyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f); R^(za) together with R^(T) if present, may form C₁-C₆-alkylene or a linear C₂-C₆-alkenylene group, where in the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene a CH₂ moiety may be replaced by a carbonyl or a C═N—R′ and/or wherein 1 or 2 CH₂ moieties may be replaced by O or S and/or wherein the linear C₁-C₆-alkylene and the linear C₂-C₆-alkenylene may be unsubstituted or substituted with R^(h); R^(a), R^(b) and R^(c) are, identical or different, H, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen, C₁-C₆-alkylene-CN, phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f); R^(b) and R^(c) together with the nitrogen they are attached may form 5- or 6-membered saturated, partially or fully unsaturated heterocyclic ring; R^(d) is H, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,  phenyl, or —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f); R^(e) is C₁-C₆-alkyl, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, wherein the alkyl, cycloalkyl moieties are unsubstituted or substituted with halogen,  phenyl and —CH₂-phenyl, wherein the phenyl rings are unsubstituted or substituted with R^(f); R^(f) is halogen, N₃, OH, CN, NO₂, —SCN, —SF₅, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, tri-C₁-C₆-alkylsilyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₁-C₆-alkoxy-C₁-C₄-alkoxy, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkoxy, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxyx-C₁-C₄-alkyl, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,  C(═O)—OR^(a), NR^(b)R^(c), C₁-C₆-alkylene-NR^(b)R^(c), O—C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN, NH—C₁-C₆-alkylene-NR^(b)R^(c), C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), or S(═O)_(m)R^(e); R^(g) is halogen, N₃, OH, CN, NO₂, —SCN, —SF₅, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, tri-C₁-C₆-alkylsilyl, C₂-C₆-alkynyl, C₁-C₆-alkoxy-C₁-C₄-alkyl, C₁-C₆-alkoxy-C₁-C₄-alkoxy, C₃-C₆-cycloalkyl, C₃-C₆-cycloalkoxy, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, C₃-C₆-cycloalkoxy-C₁-C₄-alkyl, wherein the alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl and cycloalkoxy moieties are unsubstituted or substituted with halogen,  C(═O)—OR^(a), NR^(b)R^(c), C₁-C₆-alkylene-NR^(b)R^(c), O—C₁-C₆-alkylene-NR^(b)R^(c), C₁-C₆-alkylene-CN, NH—C₁-C₆-alkylene-NR^(b)R^(c), C(═O)—NR^(b)R^(c), C(═O)—R^(d), SO₂NR^(b)R^(c), or S(═O)_(m)R^(e); R^(h) is halogen, OH, C₁-C₆-alkyl, C₃-C₆-cycloalkyl, or CN; m is 0, 1, or 2; and the N-oxides, stereoisomers, tautomers and agriculturally or veterinarily acceptable salts thereof.
 2. The compound of formula I according to claim 1, wherein A¹ is CR^(A1), A² is CR^(A2), A³ is N.
 3. The compound of formula I according to claim 1, wherein A¹ is CR^(A1), A² is N, A³ is CR^(A3).
 4. The compound of formula I according to claim 11, wherein A¹ is CR^(A1), A² is N, A³ is N.
 5. The compound of formula I according to claim 1, wherein R^(B1), R^(B2), and R^(B3), independently of each other are H, halogen, or C₁-C₆-alkyl.
 6. The compound of formula I according to claim 1, wherein R¹ is a formula YZT-1 to YZT-9, wherein

denotes attachment to the 10 membered hetaryl;

wherein R¹¹, R¹², R^(T), R^(ya), R^(yc), R^(za) and R^(zc) are as defined in claim
 1. 7. The compound of formula I according to claim 1, wherein Ar are formulas Ar-1 to Ar-20


8. A composition comprising compound of formula I according to claim 1, an N-oxide or an agriculturally acceptable salt thereof, and a further active substance.
 9. A method for combating or controlling invertebrate pests comprising contacting the pest or its food supply, habitat or breeding grounds with a pesticidally effective amount of at least one compound according to claim
 1. 10. A method for protecting growing plants from attack or infestation by invertebrate pests comprising contacting a plant, or soil or water wherein the plant is growing, with a pesticidally effective amount of at least one compound according to claim
 1. 11. A seed comprising a compound according to claim 1, or the enantiomers, diastereomers or salts thereof, in an amount of from 0.1 g to 10 kg per 100 kg of seed.
 12. (canceled)
 13. A method for treating or protecting an animal from infestation or infection by invertebrate pests comprising bringing the animal in contact with a pesticidally effective amount of at least one compound of the formula I according to claim 1 to 7, a stereoisomer thereof and/or at least one veterinarily acceptable salt thereof. 